Unsmooth reversing is one of the most common faults in the four-way reversing valve of the air conditioning system, and the airflow in the valve chamber and the shape of the slider of the reversing valve are the main factors in unsmooth reversing. In...
Background: Type 2 diabetes (T2D) has long been identified as an incurable chronic disease based on traditional means of treatment. Research now exists that suggests reversal is possible through other means that have only recently been embraced in th...
HIV-1 infection cannot be cured due to the presence of HIV-1 latently infected cells. These cells do not produce the virus, but they can resume virus production at any time in the absence of antiretroviral therapy. Therefore, people living with HIV (...
In this work, we propose both an improvement and extensions of a reverse Jensen inequality due to Wunder et al. (2021). The new proposed inequalities are fairly tight and reasonably easy to use in a wide variety of situations, as demonstrated in seve...
The latent viral reservoir represents one of the major barriers to curing HIV-1. Focus on the “kick and kill” (also called “shock and kill”) approach, in which virus expression is reactivated, and then cells producing virus ar...
According to a study by the Insurance Institute for Highway Safety (IIHS), the driving collision rate of using only the reversing camera system is lower than that of using both the reversing camera system and the reversing radar. In this article, we...
Human T-cell leukemia virus type 1 (HTLV-1), the cause of adult T-cell leukemia/lymphoma (ATLL), is a retrovirus, which integrates into the host genome and persistently infects CD4+ T-cells. Virus propagation is stimulated by (1) clonal expansion of...
The overexpression of ATP-binding cassette (ABC) transporters is a common cause of multidrug resistance (MDR) in cancers. The intracellular drug concentration of cancer cells can be decreased relative to their normal cell counterparts due to increase...
This technical procedure demonstrates a 4-step completely digital workflow for the fabrication of complete dentures in edentulous patients. The digital scan data of the edentulous arches were obtained using an intraoral scanner, followed by the fabri...
Multidrug resistance (MDR) is a central cause of chemotherapy failure and tumor recurrence and metastasis, and its mechanism involves enhanced drug efflux, target mutation, upregulation of DNA repair and remodeling of the tumor microenvironment. ABC...
Antiretroviral therapy (ART) controls human immunodeficiency virus 1 (HIV-1) replication and prevents disease progression but does not eradicate HIV-1. The persistence of a reservoir of latently infected cells represents the main barrier to a cure. “...
In recent years, control design for unmanned systems, especially a tractor–trailer system, has gained popularity among researchers. The emergence of such interest is caused by the potential reduction in cost and shortage of number of workers and labo...
Two new (1, 2 viz Rubracin D and E) and sixteen known Glyceroglycolipids (3–18) in the saprophytic fungus Tubeufia rubra (PF02-2) from decaying wood in freshwater habitat were isolated and identified. Their chemical structures were elucidated v...
Environmental perception and information processing are two key steps of active safety for vehicle reversing. Single-sensor environmental perception cannot meet the need for vehicle reversing safety due to its low reliability. In this paper, we prese...
Nucleosomes positioned on the HIV-1 5′ long terminal repeat (LTR) regulate sense transcription as well as the establishment and maintenance of latency. A negative-sense promoter (NSP) in the 3′ LTR expresses antisense transcripts with cod...
In order to improve the low efficiency and malfunction caused by the FWRV (four-way reversing valve) when the working mode of the heat pump air conditioning system changes in refrigeration and heating, it is of great significance to study the structu...
Chronic atrophic gastritis (CAG) is a key precursor in the Correa cascade leading to gastric cancer and is driven by long-standing Helicobacter pylori infection, autoimmune reactions, environmental exposures, and persistent inflammation. Emerging evi...
As interest in Internet of Things environments rapidly increases throughout the IT convergence field, compatibility with mobile devices must be provided to enable personalized services. The security of mobile platforms and applications is critical be...
Natural products originating from marine and plant materials are a rich source of chemical diversity and unique antimicrobials. Using an established in vitro model of HIV-1 latency, we screened 257 pure compounds from a marine natural product library...
Multidrug resistance (MDR) that occurs in cancer cells constitutes one of the major reasons for chemotherapy failure. The main molecular mechanism of MDR is overexpression of protein transporters from the ATP-binding cassette (ABC) superfamily, such...
Despite the success of combination antiretroviral therapy (cART), HIV persists in low- and middle-income countries (LMIC) due to emerging drug resistance and insufficient drug accessibility. Furthermore, cART does not target latently-infected CD4+ T...
We aimed to determine if not using residual neuromuscular blockade (RNB) analysis to guide neuromuscular blockade reversal administration in the postsurgical ICU resulted in consequences related to residual weakness. This single-center, prospective s...
Latently infected resting CD4+ T cells represent the principal barrier to HIV eradication. Their immunological quiescence renders them invisible to combination antiretroviral therapy (cART) and host immune surveillance, sustaining a reservoir that ma...
Recent efforts to employ ectopic Tat as a latency-reversal strategy can benefit from the identification of Tat variants with more efficient transactivation activity. Tat primarily serves as a recruiter of the host transcription elongation factor P-TE...
AIDS first emerged decades ago; however, its cure, i.e., eliminating all virus sources, is still unachievable. A critical burden of AIDS therapy is the evasive nature of HIV-1 in face of host immune responses, the so-called “latency.” Recently, a pro...
Terpenes constitute one of the largest groups of natural products. They exhibit a wide range of biological activities including antioxidant, anticancer, and drug resistance modulating properties. Saffron extract and its terpene constituents have been...
The inference of causal relations between observable phenomena is paramount across scientific disciplines; however, the means for such enterprise without experimental manipulation are limited. A commonly applied principle is that of the cause precedi...
Marine toxins (MTs) are a group of structurally complex natural products with unique toxicological and pharmacological activities. In the present study, two common shellfish toxins, okadaic acid (OA) (1) and OA methyl ester (2), were isolated from th...
The impact of sewage discharge on water quality in reversing rivers has rarely received attention. This study simulated water quality changes in Maoergang River (a water body with counter flow conditions) affected by effluent discharge from Yangjiabu...
The magnetic structure of Wiegand wires cannot be evaluated using conventional magnetization hysteresis curves. We analyzed the magnetization reversal of a Wiegand wire by measuring the first-order reversal curves (FORCs). A FeCoV Wiegand wire with a...
Geomagnetic field measurements indicate that at present we may be on the brink of the Earth’s magnetic field reversal, potentially resulting in all the accompanying negative consequences for the mankind. Mathematical modelling is necessary in o...
Stock prices are well known to exhibit behaviors that are difficult to model mathematically. Individual stocks are observed to exhibit short term price reversals and long term momentum, while their industries only exhibit momentum. Here we show that...
In this work we use the normal form theory to establish an algorithm to determine if a planar vector field is orbitally reversible. In previous works only algorithms to determine the reversibility and conjugate reversibility have been given. The proc...
There is ample evidence that synthesis of HIV-1 proviral DNA from the viral RNA genome during reverse transcription requires host factors. However, only a few cellular proteins have been described in detail that affect reverse transcription and inter...
The ‘shock-and-kill’ strategy to purge the latent HIV reservoir relies on latency-reversing agents (LRAs) to reactivate the provirus and subsequent immune-mediated killing of HIV-expressing cells. Yet, clinical trials employing histone deacetylase in...
We investigate the bridge problem for stochastic processes, that is, we analyze the statistical properties of trajectories constrained to begin and terminate at a fixed position within a time interval
Reverse logistics has become a competitive need for sustainability. Lack of resources to apply reverse logistics solutions has severely impacted many supply chains’ costs and customer service, making it impossible to meet the expectations of re...
Abstract: In the debate about the direction of time in physics, the concept of time reversal has been central. Tradition has it that time-reversal invariant laws are sufficient to state that the direction of time is non-fundamental or emergent. In th...
Background and Objectives: Metabolic and bariatric surgery (MBS) is practiced worldwide. Sugammadex was proven to have multiple benefits in reversing neuromuscular blockade (NMB) for patients with obesity undergoing MBS, but its effects on complicati...
Porcine epidemic diarrhea virus (PEDV) has continuously caused severe economic losses to the global swine industries; however, no successful vaccine against PEDV has been developed. In this study, we generated four autologous recombinant viruses, inc...
The effects of quantum mechanics dominate nanoscale devices, where Moore’s law no longer holds true. Additionally, with the recent rapid development of quantum computers, the development of reversible gates to overcome the problems of energy an...
Reversible emulsion drilling fluids can concentrate the advantages of water-based drilling fluids and oil-based drilling fluids. Most of the existing reversible emulsion drilling fluid systems are surfactant-based emulsifier systems, which have the d...
This paper is interested in establishing some new reverse Hilbert-type inequalities, by using chain rule on time scales, reverse Jensen’s, and reverse Hölder’s with Specht’s ratio and mean inequalities. To get the results, we u...
COVID-19 is caused by severe acute respiratory syndrome virus type 2 (SARS-CoV-2), which can infect both humans and animals. SARS-CoV-2 originated from bats and can affect various species capable of crossing the species barrier due to active mutation...
Topological indices collect information from the graph of molecule and help to predict properties of the underlying molecule. Zagreb indices are among the most studied topological indices due to their applications in chemistry. In this paper, we comp...
This work explores the notion of axis-reversible rings, a generalization of axis-commutative rings. The objective is to investigate their characteristics and relevance within the wider context of ring theory. This paper defines axis-reversibility and...
Background/Objectives: Hartmann’s procedure is commonly employed to manage complications of acute sigmoid diverticulitis, such as perforation or abscess formation. However, determining the optimal timing for colostomy reversal remains a topic o...
Metabolic syndrome is a constellation of five risk factors comprising central obesity, hyperglycaemia, dyslipidaemia, and hypertension, which predispose a person to cardiometabolic diseases. Many studies reported the beneficial effects of honey in re...
Reverse transcription describes the process of the transformation of single-stranded RNA into double-stranded DNA via an RNA/DNA duplex intermediate, and is catalyzed by the viral enzyme reverse transcriptase (RT). This event is a pivotal step in the...
We present linear-time algorithms computing the reversed Lempel–Ziv factorization [Kolpakov and Kucherov, TCS’09] within the space bounds of two different suffix tree representations. We can adapt these algorithms to compute the longest previous non-...
of 763