Retroviral Enzymes
A special issue of Viruses (ISSN 1999-4915). This special issue belongs to the section "Animal Viruses".
Deadline for manuscript submissions: closed (30 December 2009) | Viewed by 238543
Special Issue Editor
Interests: HIV; reverse transcription; drug resistance; genetic variation; proteolytic processing; HIV protease
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
The retroviral RNA genome encodes for three enzymes essential for virus replication: (i) the viral protease (PR), that converts the immature virion into a mature virus through the cleavage of precursor polypeptides; (ii) the reverse transcriptase (RT), responsible for the conversion of the single-stranded genomic RNA into double-stranded proviral DNA; and (iii) the integrase (IN) that inserts the proviral DNA into the host cell genome. All of them are important targets for therapeutic intervention. Knowledge on their structure and mechanism of action should help us to design better drugs against AIDS and other diseases caused by retroviruses.
Dr. Luis Menéndez-Arias
Guest Editor
Keywords
- aspartyl-proteases
- reverse transcription
- integration
- virus maturation
- antiretroviral drugs
- drug targets
- viral mutation and variability
Benefits of Publishing in a Special Issue
- Ease of navigation: Grouping papers by topic helps scholars navigate broad scope journals more efficiently.
- Greater discoverability: Special Issues support the reach and impact of scientific research. Articles in Special Issues are more discoverable and cited more frequently.
- Expansion of research network: Special Issues facilitate connections among authors, fostering scientific collaborations.
- External promotion: Articles in Special Issues are often promoted through the journal's social media, increasing their visibility.
- e-Book format: Special Issues with more than 10 articles can be published as dedicated e-books, ensuring wide and rapid dissemination.
Further information on MDPI's Special Issue polices can be found here.