Feature Papers in Gastrointestinal Disorders in 2025–2026

A special issue of Gastrointestinal Disorders (ISSN 2624-5647).

Deadline for manuscript submissions: 31 December 2026 | Viewed by 105

Special Issue Editor


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Guest Editor
1. Department of Medicine, Texas Tech University Health Sciences Center, El Paso, TX 79905, USA
2. Department of Internal Medicine, Texas Tech University Medical Center, Paul L. Foster School of Medicine, El Paso, TX 79905, USA
3. School of Medicine, University of Queensland, Brisbane, Australia
Interests: the physiology, pathophysiology and pharmacology of gastrointestinal smooth muscles; the role of the enteric nervous system and electrical activity relating to GI motility disorders; the brain–gut integration and gut microbiota in functional GI disorders as well as the development of electrical stimulation and new pharmacology in treating these entities
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Special Issue Information

Dear Colleagues,

In 2023–2024, we launched the Special Issue “Feature Papers in Gastrointestinal Disorders in 2023–2024” and compiled 17 interesting papers.

In the new version, we aim to curate high-quality original research and review articles highlighting cutting-edge developments in gastroenterology between 2025 and 2026. We welcome submissions addressing, but not limited to, the following themes:

  • Inflammatory bowel disease;
  • Gastrointestinal cancer (colorectal cancer, esophageal cancer, etc.);
  • Coeliac disease;
  • Diet;
  • Crohn’s disease;
  • Gastroparesis;
  • Hepatocellular carcinoma;
  • Gut microbiota;
  • Irritable bowel syndrome;
  • Metabolic syndrome;
  • Gut–brain axis.

Prof. Dr. Richard W. McCallum
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Gastrointestinal Disorders is an international peer-reviewed open access quarterly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 1400 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • inflammatory bowel disease
  • gastrointestinal cancer
  • coeliac disease
  • diet
  • Crohn’s disease
  • gastroparesis
  • hepatocellular carcinoma
  • gut microbiota
  • irritable bowel syndrome
  • metabolic syndrome
  • gut–brain axis

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Published Papers (1 paper)

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12 pages, 616 KiB  
Systematic Review
Spontaneous Hyperinflation of Intragastric Balloons: A Systematic Review
by Mina Guirgis, Parveen Kumar, Jason Laurens and Brijesh Madhok
Gastrointest. Disord. 2025, 7(3), 55; https://doi.org/10.3390/gidisord7030055 (registering DOI) - 24 Aug 2025
Abstract
Background: Spontaneous intragastric balloon hyperinflation (SIBH) is a rare and concerning complication of intragastric balloons (IGBs). The mechanisms underlying SIBH remain unclear. This systematic review aims to synthesise the current evidence regarding the clinical presentation, management, complications, and hypothesised aetiologies of SIBH. [...] Read more.
Background: Spontaneous intragastric balloon hyperinflation (SIBH) is a rare and concerning complication of intragastric balloons (IGBs). The mechanisms underlying SIBH remain unclear. This systematic review aims to synthesise the current evidence regarding the clinical presentation, management, complications, and hypothesised aetiologies of SIBH. Methods: A comprehensive literature search was conducted using PubMed, EMBASE, MEDLINE, and Ebsco databases. Studies reporting on cases of SIBH were identified and reviewed. Data points were extracted on patient presentation, management strategies, complications, outcomes, and proposed mechanisms. Results: Eighteen publications describing 29 patients with SIBH were included. The most common clinical presentation was gastric outlet obstruction (86%). Emergency endoscopy was required in 96% of cases, with balloon removal performed in 82%. Reported complications included acute pancreatitis and mucosal erosions; however, neither long-term morbidity nor mortality was observed. Microbial colonisation was hypothesised as the underlying cause in 62% of publications, supported by culture findings from balloon contents in 90% of cases, most commonly isolating gas-producing organisms such as Candida (80%) and anaerobic bacteria (40%). Conclusions: SIBH most frequently presents with gastric outlet obstruction and typically necessitates emergency endoscopic intervention. Gas-producing microbial colonisation of the balloon is the predominant hypothesised aetiology. Preventive strategies targeting microbial colonisation may be crucial in reducing the incidence of SIBH. Full article
(This article belongs to the Special Issue Feature Papers in Gastrointestinal Disorders in 2025–2026)
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