Special Issue "Insights into Antisense Long Non-Coding RNAs Metabolism and Expression"

A special issue of Non-Coding RNA (ISSN 2311-553X).

Deadline for manuscript submissions: 30 September 2021.

Special Issue Editor

Dr. Maxime Wery
E-Mail Website
Guest Editor
ncRNA, Epigenetic and Genome Fluidity, Institut Curie, Sorbonne Université, CNRS UMR 3244, Paris, France

Special Issue Information

Dear Colleagues,

While initially considered as pervasive transcripts devoid of any regulatory function, long non-coding (lnc)RNAs have progressively emerged as key players involved in multiple cellular processes.

Among the different classes of lncRNAs, “antisense” (as)lncRNAs are synthesized from the DNA strand opposite to “sense” genes. Over the last few years, they have attracted a lot of attention given their potential to regulate gene expression.

Despite their regulatory importance, aslncRNAs still remain poorly characterized. One reason for this lack of global information on aslncRNAs appears to be their low cellular abundance. In fact, pioneering studies in yeast have highlighted the role of evolutionarily conserved RNA decay machineries in tightly controlling aslncRNAs levels.

In this context, this Special Issue will focus on the expression and the metabolism of aslncRNAs, including antisense transcription, the regulation of aslncRNAs expression and decay, the interactions of aslncRNAs with RNA/DNA, aslncRNAs as regulators of gene expression and other processes, aslncRNAs expression in cancer and diseases, and evolutionary aspects of aslncRNAs.

Manuscripts reporting original research, short communications, methods, and reviews will be considered.

Dr. Maxime Wery
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All papers will be peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Non-Coding RNA is an international peer-reviewed open access quarterly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 1600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.


  • Antisense transcription
  • aslncRNAs expression and decay
  • aslncRNAs metabolism
  • Regulatory aslncRNAs
  • aslncRNAs in cancer and disease

Published Papers

This special issue is now open for submission, see below for planned papers.

Planned Papers

The below list represents only planned manuscripts. Some of these manuscripts have not been received by the Editorial Office yet. Papers submitted to MDPI journals are subject to peer-review.

Title: Antisense long non-coding RNAs located next to transcription factors and their roles in participation in transcriptional regulation
Authors: Yifan Bao; Anagha Gogate; Rajvi Parikh; Shiv Patel; Ross Bernstein; Xiao-bo Zhong
Affiliation: Department of Pharmaceutical Sciences, School of Pharmacy, University of Connecticut, Storrs, CT 06269, USA

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