Special Issue "Epigenetics and Viral infection"

A special issue of Viruses (ISSN 1999-4915).

Deadline for manuscript submissions: 30 September 2020.

Special Issue Editor

Dr. Italo Tempera
Website
Guest Editor
Gene Expression and Regulation, The Wistar Institute, 3601 Spruce Street, 19104 Philadelphia, PA, USA
Interests: epigenetic regulation of herpesviruses infection

Special Issue Information

Dear Colleagues,

It is well known that to support infection, viruses co-opt cellular mechanisms that control transcription. Chromatin composition and chromatin structure are important regulators of gene expression. In the past years, the role of chromatin and chromatin-modifying enzymes has been explored in the context of virus-host interaction demonstrating the importance of viral infection on the host epigenome and the role of epigenetics in controlling viral replication. The goal of this Special Issue is to provide a collection of the most significant advances in the field of epigenetics and viral infection. We expect to receive manuscripts outlining how viruses and their host each attempt to use epigenetics to gain control of the other’s transcription to achieve their own ends.

Dr. Italo Tempera
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All papers will be peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Viruses is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2000 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • epigenetics
  • chromatin
  • gene regulation
  • viral infection
  • chromatin structure
  • virus-host interactions

Published Papers (1 paper)

Order results
Result details
Select all
Export citation of selected articles as:

Review

Open AccessReview
Regulation of the Human Papillomavirus Life Cycle by DNA Damage Repair Pathways and Epigenetic Factors
Viruses 2020, 12(7), 744; https://doi.org/10.3390/v12070744 (registering DOI) - 10 Jul 2020
Abstract
Human papillomaviruses are the causative agents of cervical and other anogenital cancers along with approximately 60% of oropharyngeal cancers. These small double-stranded DNA viruses infect stratified epithelia and link their productive life cycles to differentiation. HPV proteins target cellular factors, such as those [...] Read more.
Human papillomaviruses are the causative agents of cervical and other anogenital cancers along with approximately 60% of oropharyngeal cancers. These small double-stranded DNA viruses infect stratified epithelia and link their productive life cycles to differentiation. HPV proteins target cellular factors, such as those involved in DNA damage repair, as well as epigenetic control of host and viral transcription to regulate the productive life cycle. HPVs constitutively activate the ATM and ATR DNA repair pathways and preferentially recruit these proteins to viral genomes to facilitate productive viral replication. In addition, the sirtuin deacetylases along with histone acetyltransferases, including Tip60, are targeted in HPV infections to regulate viral transcription and replication. These pathways provide potential targets for drug therapy to treat HPV-induced disease. Full article
(This article belongs to the Special Issue Epigenetics and Viral infection)
Back to TopTop