Skip to Content
You are currently on the new version of our website. Access the old version .

1,172 Results Found

  • Article
  • Open Access
1 Citations
1,849 Views
15 Pages

Extraction of Arbors from Terrestrial Laser Scanning Data Based on Trunk Axis Fitting

  • Song Liu,
  • Yuncheng Deng,
  • Jianpeng Zhang,
  • Jinliang Wang and
  • Di Duan

13 July 2024

Accurate arbor extraction is an important element of forest surveys. However, the presence of shrubs can interfere with the extraction of arbors. Addressing the issues of low accuracy and weak generalizability in existing Terrestrial Laser Scanning (...

(This article belongs to the Section Forest Inventory, Modeling and Remote Sensing)
  • Article
  • Open Access
40 Citations
5,555 Views
19 Pages

28 November 2020

Global inspection of large-scale tunnels is a fundamental yet challenging task to ensure the structural stability of tunnels and driving safety. Advanced LiDAR scanners, which sample tunnels into 3D point clouds, are making their debut in the Tunnel...

(This article belongs to the Section Remote Sensors)
  • Article
  • Open Access
3 Citations
2,339 Views
30 Pages

Natural Extract Combination Modulates Intestinal Barrier and Hepatic Cholesterol via the Gut–Liver Axis In Vitro

  • Francesca Uberti,
  • Simone Mulè,
  • Francesca Parini,
  • Matteo Musu and
  • Rebecca Galla

Background/Objectives: The gut–liver axis plays a central role in cholesterol homeostasis, linking intestinal absorption, microbial metabolites, and hepatic lipid regulation. Dysregulation of this axis contributes to hypercholesterolemia and ca...

(This article belongs to the Section Physical Pharmacy and Formulation)
  • Article
  • Open Access
5 Citations
2,180 Views
22 Pages

Therapeutic Benefits of Nano-Echinacea Extract on Reproductive Injury Induced by Polystyrene Plastic Materials in Rat Model via Regulating Gut–Brain Axis

  • Yi-Yuh Hwang,
  • Sabri Sudirman,
  • Pei-Xuan Tsai,
  • Chine-Feng Mao and ,
  • Athira Johnson,
  • Tai-Yuan Chen,
  • Deng-Fwu Hwang and
  • Zwe-Ling Kong
  • + 3 authors+ 0 author

Plastics pollution is a critical global environmental issue, with growing concern over the increasing presence of nanoplastic particles. Plastics are major environmental pollutants that adversely affect human health, particularly when plastics from f...

(This article belongs to the Section Molecular Pharmacology)
  • Article
  • Open Access
16 Citations
10,119 Views
17 Pages

Effects of Saffron Extract (Affron®) with 100 mg/kg and 200 mg/kg on Hypothalamic–Pituitary–Adrenal Axis and Stress Resilience in Chronic Mild Stress-Induced Depression in Wistar Rats

  • Chae-Young Kim,
  • Kayoung Ko,
  • Seo-Hee Choi,
  • Miri Jo and ,
  • Jinhye Kim,
  • Sunmi Yoon,
  • Isaac Jinwon Yi,
  • María Inés Morán-Valero,
  • Min-Young Kwon and
  • Sun-Shin Yi
  • + 6 authors+ 1 author

21 November 2023

Stress-related symptoms are a global concern, impacting millions of individuals, yet effective and safe treatments remain scarce. Although multiple studies have highlighted the stress- alleviating properties of saffron extract, the underlying mechani...

(This article belongs to the Section Nutrition and Public Health)
  • Article
  • Open Access
12 Citations
3,870 Views
23 Pages

3 September 2025

Neuroinflammation plays a central role in the pathogenesis of Alzheimer’s disease (AD), with amyloid-β (Aβ) deposition and neurofibrillary tangles driving both central and peripheral inflammatory responses. This study investigated the...

(This article belongs to the Special Issue Molecular Mechanisms of Alzheimer’s Disease)
  • Article
  • Open Access
3 Citations
3,752 Views
28 Pages

10 December 2025

Polyphenols, as natural compounds abundant in plant-derived foods, have been recognised for their human health benefits. This study evaluates the multifunctional properties of BiombalanceTM (BB), a grape seed extract rich in oligomeric procyanidins,...

(This article belongs to the Special Issue Antioxidant Activity of Grape and Grape By-Products)
  • Article
  • Open Access
1 Citations
755 Views
15 Pages

Aging-Feature-Extraction Method Based on the Short-Axis Diameter Ratio of Serviced Rubber Strips

  • Yujia Chen,
  • Bo Xu,
  • Yun Tan,
  • Jia He and ,
  • Youchun Pi,
  • Hu Li,
  • Chunyu Meng,
  • Yiyi Liang,
  • Mengyue Bai and
  • Yuansi Wei
  • + 5 authors+ 0 author

6 March 2026

In this paper, aiming at the aging problem of rubber sealing strips in key parts of hydropower units under long-term load, this study proposes a quantitative aging-feature-extraction technique centered on the ratio of the short-axis length to the ori...

(This article belongs to the Special Issue Aging Behavior and Durability of Polymer Materials, 2nd Edition)
  • Article
  • Open Access
1,464 Views
13 Pages

6 August 2024

The operational state of a rotor system directly affects its working efficiency, and the axis trajectory can accurately characterize this state. Therefore, a method for extracting axis motion trajectory characteristics based on distance sequence repr...

  • Article
  • Open Access
15 Citations
2,279 Views
22 Pages

28 December 2023

For the problem that the fault states of parallel shaft gearboxes are difficult to identify, a diagnostic method is proposed to optimize variational modal decomposition (VMD) and t-distributed stochastic neighbor embedding (t-SNE) using an improved d...

(This article belongs to the Special Issue Practical Applications of New Optimization Methods and Intelligent Control)
  • Article
  • Open Access
3 Citations
1,889 Views
16 Pages

Online Optical Axis Parallelism Measurement Method for Continuous Zoom Camera Based on High-Precision Spot Center Positioning Algorithm

  • Chanchan Kang,
  • Yao Fang,
  • Huawei Wang,
  • Feng Zhou and ,
  • Zeyue Ren and
  • Feixiang Han
  • + 1 author+ 0 author

29 October 2024

Ensuring precise alignment of the optical axis is critical for achieving high-quality imaging in continuous zoom cameras. However, existing methods for measuring optical axis parallelism often lack accuracy and fail to assess parallelism across the e...

(This article belongs to the Special Issue Advancements in Optical Measurement Techniques and Applications)
  • Article
  • Open Access
1 Citations
434 Views
56 Pages

An Integrated Engineering Methodology for the Design and Industrial Validation of a Three-Axis Cartesian Manipulator for Automated Injection Runner Extraction

  • João Barros,
  • Francisco J. G. Silva,
  • Raul D. S. G. Campilho,
  • Naiara P. V. Sebbe and ,
  • Rúben D. F. S. Costa,
  • André F. V. Pedroso and
  • Arnaldo G. Pinto
  • + 2 authors+ 0 author

26 September 2026

Industrial automation systems operating within geometrically constrained manufacturing environments require engineering approaches capable of integrating functional requirements, mechanical design, numerical verification, and industrial implementatio...

(This article belongs to the Special Issue Digital Transformation Technologies for Smart and Advanced Manufacturing)
  • Article
  • Open Access
1,222 Views
36 Pages

9 June 2026

Accurately capturing the Kuroshio’s main axis and its multiscale frontal variations remains challenging due to the constraints of traditional fixed-section extraction methods. Here, we develop an adaptive iterative tracking algorithm utilizing...

(This article belongs to the Special Issue Recent Progress in Ocean Fronts)
  • Article
  • Open Access
3 Citations
1,645 Views
25 Pages

16 April 2025

Metformin disinfection byproducts Y and C have emerged as pollutants of concern in drinking water systems and are suspected to possess significant toxicity to mammals. However, effective strategies to mitigate the effects of Y and C exposure in mamma...

  • Article
  • Open Access
653 Views
26 Pages

20 July 2026

Air-gap variation in elevator brakes affects armature actuation, brake-shoe release/contact processes, and transient vibration responses, making it an important indicator for brake condition monitoring. However, long-duration vibration recordings acq...

(This article belongs to the Section Physical Sensors)
  • Article
  • Open Access
3 Citations
2,512 Views
24 Pages

9 September 2025

This study presents a high-precision underwater 3D reconstruction system based on rotating laser scanning. The system adopts a modeling framework that combines air-based camera calibration with refraction compensation. A five-stage image preprocessin...

(This article belongs to the Section Optical Sensors)
  • Article
  • Open Access
4 Citations
2,071 Views
21 Pages

27 May 2024

Vortex electromagnetic wave radar carrying orbital angular momentum can compensate for the deficiency of planar electromagnetic wave radar in detecting motion parameters perpendicular to the direction of electromagnetic wave propagation, thus providi...

(This article belongs to the Topic Radar Signal and Data Processing with Applications)
  • Article
  • Open Access
16 Citations
5,655 Views
34 Pages

Impact of Lyophilized Milk Kefir-Based Self-Nanoemulsifying System on Cognitive Enhancement via the Microbiota–Gut–Brain Axis

  • Mai M. Anwar,
  • Amira A. Boseila,
  • Abeer A. Mabrouk,
  • Abdelfattah A. Abdelkhalek and
  • Amr Amin

7 October 2024

Chronic inflammatory bowel disorders (IBDs) are characterized by altered intestinal permeability, prompting inflammatory, oxidative stress, and immunological factors. Gut microbiota disorders impact brain function via the bidirectional gut–brai...

  • Article
  • Open Access
4 Citations
1,540 Views
29 Pages

DualHet-YOLO: A Dual-Backbone Heterogeneous YOLO Network for Inspection Robots to Recognize Yellow-Feathered Chicken Behavior in Floor-Raised House

  • Yaobo Zhang,
  • Linwei Chen,
  • Hongfei Chen,
  • Tao Liu and ,
  • Jinlin Liu,
  • Qiuhong Zhang,
  • Mingduo Yan,
  • Kaiyue Zhao,
  • Shixiu Zhang and
  • Xiuguo Zou
  • + 5 authors+ 0 author

The behavior of floor-raised chickens is closely linked to their health status and environmental comfort. As a type of broiler chicken with special behaviors, understanding the daily actions of yellow-feathered chickens is crucial for accurately chec...

(This article belongs to the Special Issue Key Technology Research and Applications of Agricultural Inspection Robots Based on Machine Vision and Artificial Intelligence)
  • Article
  • Open Access
1 Citations
1,285 Views
29 Pages

From Microbiota to Metabolomics: How Corylus heterophylla Fisch. Male Flower Extract Shields Mice from Cognitive Decline

  • Wei Lu,
  • Yujie Li,
  • Xinyuan Liao,
  • Han Hu and ,
  • Bolin Zhang,
  • Lisong Liang and
  • Haina Gao
  • + 2 authors+ 0 author

18 December 2025

Background/Objectives: Emerging evidence suggests that hippocampal neuroinflammation (HNF) drives cognitive decline via dysregulation of the microbiota-gut-brain axis. Corylus heterophylla Fisch. male flower extract (CFE), a flavonoid-rich by-product...

(This article belongs to the Special Issue Effects of Plant Extracts on Human Health—2nd Edition)
  • Article
  • Open Access
1 Citations
1,097 Views
18 Pages

Rapid Inspection of Large-Span Roofs Using Un-Manned Aerial Vehicle Oblique Photography and Point Cloud Data

  • Wentao Li,
  • Hongbiao Zhu,
  • Tianqi Yi,
  • Shuai Wang and ,
  • Haokai Huang,
  • Hui Wang and
  • Xiaoxiong Zha
  • + 2 authors+ 0 author

19 November 2025

Traditional methods for inspecting large-span roofs face challenges such as extensive measurement areas, difficult positioning, low efficiency, and insufficient utilization of secondary analysis of inspection data. To address these issues, this study...

(This article belongs to the Section Building Structures)
  • Article
  • Open Access
1 Citations
937 Views
17 Pages

An Approach for Spectrum Extraction Based on Canny Operator-Enabled Adaptive Edge Extraction and Centroid Localization

  • Ao Li,
  • Xinlan Ge,
  • Zeyu Gao,
  • Qiang Yuan and ,
  • Yong Chen,
  • Chao Yang,
  • Licheng Zhu,
  • Shiqing Ma,
  • Shuai Wang and
  • Ping Yang
  • + 5 authors+ 0 author

10 February 2026

In adaptive optics systems, high spatial resolution detection is a core prerequisite for achieving accurate wavefront correction. High spatial resolution wavefront measurement based on the traditional Shack-Hartmann technique is limited by the densit...

(This article belongs to the Special Issue Challenges and Future Directions in Adaptive Optics Technology, 2nd Edition)
  • Essay
  • Open Access
443 Views
13 Pages

This paper proposes a novel shielded quad-axis differential through-silicon via (SQDTSV) structure. Initially, the parasitic parameters are extracted, and the applicability of the equivalent circuit model and analytical formulas is verified through a...

(This article belongs to the Section Circuit and Signal Processing)
  • Article
  • Open Access
1 Citations
379 Views
20 Pages

Camellia nitidissima Flower Extract Alleviates Dermal Papilla Cell Dysfunction by Regulating 11β-HSD1 and the TGF-β2/Smad and Wnt/β-Catenin Pathways

  • Meng Zhang,
  • Zhenyu Qin,
  • Timson Chen,
  • Zhizhen Li and ,
  • Ya Chen,
  • Ling Ma,
  • Guangli Wang and
  • Jing Wang
  • + 3 authors+ 0 author

Psychological stress activates the local hypothalamic–pituitary–adrenal (HPA)-like axis in hair follicles, leading to cortisol overproduction and dysfunction of dermal papilla cells (DPCs). However, effective natural ingredients targeting...

(This article belongs to the Section Bioorganic Chemistry and Medicinal Chemistry)
  • Article
  • Open Access
736 Views
24 Pages

Grape Seed Proanthocyanidins Enhance Time-Dependent HO-1 Activation and Improve Redox Homeostasis in Obesity-Induced Hepatic Dysfunction

  • María Zamora-Úbeda,
  • Aina Gironès-Garreta,
  • Julieta Cirasino,
  • Josep M. Del Bas and ,
  • Jorge R. Soliz-Rueda,
  • Miquel Mulero and
  • Enrique Calvo
  • + 2 authors+ 0 author

Metabolic dysfunction-associated steatotic liver disease (MASLD) is characterized by impaired metabolic flexibility, oxidative stress, and disruption of the temporal coordination of hepatic processes. Obesogenic diets contribute to this dysfunction b...

(This article belongs to the Special Issue Oxidative Stress in Hepatic Diseases)
  • Article
  • Open Access
544 Views
29 Pages

Protective Effects of Fructus mume Extract Against Deoxynivalenol-Induced Intestinal and Liver Injury in Mice

  • Jiali Liu,
  • Shipeng Liu,
  • Xiaowei Zhou,
  • Zhaoran Zhong and ,
  • Qingyue Hu,
  • Qinjin Li,
  • Zhaoyan Lin,
  • Xiaohong Huang and
  • Bohan Zheng
  • + 4 authors+ 0 author

16 July 2026

Deoxynivalenol (DON), a prevalent mycotoxin, induces intestinal and hepatic injury. Fructus mume extract (FME) possesses bioactive properties, yet its protective role against DON remains unclear. This study aimed to investigate the protective mechani...

(This article belongs to the Section Microbiology)
  • Article
  • Open Access
307 Views
21 Pages

28 September 2026

Endothelial cell senescence is a key contributor to vascular ageing and cardiovascular diseases. Asiaticoside, a pentacyclic triterpenoid saponin from Centella asiatica, exhibits anti-inflammatory and antioxidant activities, yet its potential to modu...

(This article belongs to the Special Issue Advances in Chemical Biology of Blood Vessels: From Molecular Interactions to Prospective Targets)
  • Article
  • Open Access
5,237 Views
7 Pages

Inonotus obliquus, which is parasitic on birch and other trees, is a fungus in the family Hymenochaetaceae. In this study, we investigated whether Inonotus obliquus extracts used in traditional medicine were decreased in the expression of matrix meta...

(This article belongs to the Special Issue Feature Papers in Cosmetics in 2020)
  • Article
  • Open Access
48 Citations
8,521 Views
17 Pages

7 December 2020

Human Activity Recognition (HAR) using embedded sensors in smartphones and smartwatch has gained popularity in extensive applications in health care monitoring of elderly people, security purpose, robotics, monitoring employees in the industry, and o...

(This article belongs to the Special Issue Selected Papers from IEEE ICKII 2020)
  • Article
  • Open Access
8 Citations
2,301 Views
20 Pages

Spinach Extract Reduces Kidney Damage in Diabetic Rats by Impairing the AGEs/RAGE Axis

  • Javier Flores-Estrada,
  • Agustina Cano-Martínez,
  • Luz Ibarra-Lara,
  • Adriana Jiménez and ,
  • Carmen Palacios-Reyes,
  • Luis J. Pinto García,
  • María G. Ortiz-López,
  • Olga Nelly Rodríguez-Peña and
  • Luis Barbo Hernández-Portilla
  • + 4 authors+ 0 author

The interaction between advanced glycation end products (AGEs) and their RAGE receptor (AGEs/RAGE axis) triggers several signaling pathways that lead to the development of diabetic nephropathy (DN). One of the most studied AGEs is Nε-(1-Carbo...

(This article belongs to the Section Bioactives and Nutraceuticals)
  • Article
  • Open Access
26 Citations
10,260 Views
26 Pages

Hericium erinaceus Extract Exerts Beneficial Effects on Gut–Neuroinflammaging–Cognitive Axis in Elderly Mice

  • Erica Cecilia Priori,
  • Daniela Ratto,
  • Fabrizio De Luca,
  • Anna Sandionigi and ,
  • Elena Savino,
  • Francesca Giammello,
  • Marcello Romeo,
  • Federico Brandalise,
  • Elisa Roda and
  • Paola Rossi
  • + 5 authors+ 0 author

28 December 2023

Ageing is a biological phenomenon that determines the impairment of cognitive performances, in particular, affecting memory. Inflammation and cellular senescence are known to be involved in the pathogenesis of cognitive decline. The gut microbiota&nd...

(This article belongs to the Collection Molecular Mechanisms of Aging)
  • Article
  • Open Access
12 Citations
3,805 Views
18 Pages

29 January 2023

Ulcerative colitis is a chronic inflammatory bowel disease characterized by colonic mucosal inflammation, intestinal microflora imbalance, and intestinal permeability. It is essential to develop natural compounds with anti-inflammatory and intestinal...

(This article belongs to the Special Issue Functional Food and Chronic Disease II)
  • Article
  • Open Access
462 Views
20 Pages

Green Pomegranate Waste Extract Modulates Macrophage Immunometabolism by Suppressing the ACLY–ME1 Axis and Promotes Pro-Resolving Macrophage Functions

  • Paolo Convertini,
  • Simona Todisco,
  • Michela Marsico,
  • Alessandro Santarsiere and ,
  • Ernesto Santoro,
  • Antonio Evidente,
  • Pierluigi Reveglia,
  • Lucia Lecce,
  • Stefano Superchi and
  • Vittoria Infantino
  • + 6 authors+ 1 author

Background: Immunometabolic reprogramming is increasingly recognized as a fundamental driver of macrophage inflammatory activation. Although pomegranate polyphenols have been widely investigated for their anti-inflammatory activity, the underlying me...

(This article belongs to the Special Issue Immune Cell Reprogramming: Molecular Mechanisms and Therapeutic Approaches)
  • Review
  • Open Access
22 Citations
6,559 Views
18 Pages

The Beneficial Effects of Natural Extracts and Bioactive Compounds on the Gut-Liver Axis: A Promising Intervention for Alcoholic Liver Disease

  • Liang Zhao,
  • Shaoxuan Wang,
  • Nanhai Zhang,
  • Jingxuan Zhou and ,
  • Arshad Mehmood,
  • Rifat Nowshin Raka,
  • Feng Zhou and
  • Lei Zhao
  • + 3 authors+ 0 author

Alcoholic liver disease (ALD) is a major cause of morbidity and mortality worldwide. It can cause fatty liver (steatosis), steatohepatitis, fibrosis, cirrhosis, and liver cancer. Alcohol consumption can also disturb the composition of gut microbiota,...

(This article belongs to the Special Issue Diet and Resident Microbiota: The Protective Effects of Natural Antioxidants on the Intestinal Mucosa)
  • Article
  • Open Access
4 Citations
4,368 Views
26 Pages

Amelioration of Alcoholic Liver Disease by Activating PXR-Cytochrome P450s Axis with Blackberry Extract

  • Ting Xiao,
  • Zhenghong Guo,
  • Min Fu,
  • Jiaoyan Huang and ,
  • Xiaowei Wang,
  • Yuqing Zhao,
  • Ling Tao and
  • Xiangchun Shen
  • + 3 authors+ 0 author

Blackberry is widely used in diets for its rich biological phytochemicals and health benefits. However, the relationship between the effect of blackberry extract (BBE) on ameliorating alcoholic liver disease (ALD) and the PXR-Cytochrome P450s axis in...

(This article belongs to the Topic Discovery of Bioactive Compounds from Natural Organisms and Their Molecular Mechanisms against Diseases)
  • Review
  • Open Access
1,490 Views
19 Pages

24 September 2026

Population ageing is associated with a rising burden of cognitive decline, dementia and late-life affective disorders. Grape- and wine-derived (poly)phenols represent a chemically diverse group of bioactives whose biological relevance is shaped by st...

(This article belongs to the Special Issue Lifestyle, Diet, Wine and Health)
  • Article
  • Open Access
1,055 Views
18 Pages

Modulation of the Gut–Liver Axis and Nrf2/HO-1-Mediated Antioxidant Defense by Styela plicata Extract Against Alcoholic Liver Injury

  • Qiuzhe Li,
  • Yuanyuan Liu,
  • Shuo Shan,
  • Yuxi Wen and ,
  • Xue Wu,
  • Siquan Xie,
  • Bin Liu,
  • Chao Zhao and
  • Weichao Chen
  • + 4 authors+ 0 author

Styela plicata, an edible ascidian rich in diverse bioactive constituents, represents a promising source of marine natural products for therapeutic discovery. Here, bioactive components from a 95% ethanol extract of S. plicata (ESP) were characterize...

(This article belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)
  • Article
  • Open Access
2 Citations
2,236 Views
25 Pages

Background/Objectives: Botanical and nutraceutical approaches have increasingly been considered as alternatives or complements to conventional lipid-lowering therapies, particularly in individuals with mild-to-moderate dyslipidemia or statin intolera...

(This article belongs to the Section Cell Biology and Pathology)
  • Article
  • Open Access
1 Citations
1,280 Views
21 Pages

Aqueous Extract of Fructus Choerospondiatis Peel Suppresses Vascular Inflammation and Alleviates Atherosclerosis via AKT/c-FOS/IL-6 Axis

  • Andong Wu,
  • Jiayi Dong,
  • Jiankun Liu,
  • Xueting Gong and ,
  • Xueer Li,
  • Bingbing Zhou,
  • Ming Wan,
  • Weixin Lv,
  • Jiayu Qiu and
  • Xiao-Li Tian
  • + 8 authors+ 3 authors

19 December 2025

Background: Atherosclerosis is the pathological basis for lethal cardio-cerebral vascular diseases, such as coronary artery disease and stroke. Fructus Choerospondiatis (FC) has demonstrated cardiac protective effects in multiple ethnomedicine. Wheth...

(This article belongs to the Special Issue Preventive and Therapeutic Nutraceuticals)
  • Article
  • Open Access
2 Citations
953 Views
23 Pages

1 March 2026

Background: The regulation of glucose metabolism is contingent on a multifaceted interaction between intestinal absorption, pancreatic endocrine function, and the hepatic response to insulin. Axis disruption contributes to insulin resistance and type...

(This article belongs to the Section Phytochemicals and Human Health)
  • Article
  • Open Access
7 Citations
2,694 Views
22 Pages

Liupao Tea Extract Alleviates Rheumatoid Arthritis in Mice by Regulating the Gut–Joint Axis Mediated via Fatty Acid Metabolism

  • Ying Tong,
  • Zhiyong She,
  • Xueting Lin,
  • Jichu Luo and ,
  • Xuan Guan,
  • Mingsen Wen,
  • Li Huang,
  • Bao Yang,
  • Xiaoying Liang and
  • Qisong Zhang
  • + 11 authors+ 6 authors

18 August 2025

As a highly disabling chronic inflammatory disease, rheumatoid arthritis (RA) necessitates novel interventions. Liupao tea is a traditional Chinese dark tea known for its favorable anti-inflammatory properties. This study aims to elucidate the active...

(This article belongs to the Section Nutraceuticals, Functional Foods, and Novel Foods)
  • Review
  • Open Access
17 Citations
5,514 Views
26 Pages

Recent Technological Advances in Phenolic Compounds Recovery and Applications: Source of Nutraceuticals for the Management of Diabetes

  • Marisol Dias,
  • Marina Romaní-Pérez,
  • Aloia Romaní,
  • Aimara de la Cruz and ,
  • Lorenzo Pastrana,
  • Pablo Fuciños and
  • Isabel R. Amado
  • + 2 authors+ 0 author

15 September 2022

Background: Phenolic compounds are food-derived bioactive compounds well-known for their antioxidant and anti-inflammatory properties. They are in the spotlight for the management of diabetes due to their positive effects on glucose homeostasis. Mate...

(This article belongs to the Section Food Science and Technology)
  • Article
  • Open Access
572 Views
30 Pages

Thymus serpyllum Extract Improves Gastrointestinal Symptoms and Modulates Fecal Gut Microbiome Composition in a Multicenter, Randomized, Placebo-Controlled Clinical Trial

  • Raquel López-Zambrano,
  • Jorge García-García,
  • Laura López-Escánez,
  • Teresa Vezza and ,
  • Luckman Gbati,
  • Rafael Palacios-López,
  • Benita Martin-Castaño,
  • Gonzalo Vargas-Castillo,
  • Margarita Martínez-Zaldivar and
  • Julio Gálvez
  • + 15 authors+ 10 authors

28 September 2026

Background/Objectives: Functional gastrointestinal discomfort is highly prevalent and affects up to 40% of the global population and remains challenging to manage due to its multifactorial nature. Usual interventions include dietary and lifestyle mod...

(This article belongs to the Section Endocrinology and Metabolic Diseases)
  • Article
  • Open Access
384 Views
21 Pages

Formononetin Alleviates Cigarette Smoke Extract-Induced Lung Injury in Mice with Gut Microbiota and Taurine/SLC6A6/NF-κB Modulation

  • Zheng Ma,
  • Sen Hu,
  • Zhongting Lv,
  • Shuang Liu and ,
  • Jia Yu,
  • Jie Zhang,
  • Hui Tian and
  • Li Ren
  • + 3 authors+ 0 author

3 September 2026

Cigarette smoke exposure is a major preventable risk factor for respiratory disease and drives oxidative and inflammatory lung injury, highlighting the urgent need for safe, multi-target interventions beyond conventional anti-inflammatory therapy. Fo...

(This article belongs to the Special Issue Feature Papers in Food Chemistry—4th Edition)
  • Article
  • Open Access
8 Citations
15,059 Views
13 Pages

Acute Effect of a Saffron Extract (Safr’InsideTM) and Its Main Volatile Compound on the Stress Response in Healthy Young Men: A Randomized, Double Blind, Placebo-Controlled, Crossover Study

  • Camille Pouchieu,
  • Line Pourtau,
  • Julie Brossaud,
  • David Gaudout and ,
  • Jean-Benoit Corcuff,
  • Lucile Capuron,
  • Nathalie Castanon and
  • Pierre Philip
  • + 3 authors+ 0 author

27 June 2023

According to animal studies, saffron and its main volatile compound safranal may reduce biological and behavioral signs of acute stress. However, little is known about its impact in humans. This study investigated the acute effect of a saffron extrac...

(This article belongs to the Special Issue Nutraceuticals and Human Health and Disease)
  • Article
  • Open Access
1 Citations
10,332 Views
17 Pages

Calcium Supplement Combined with Dietary Supplement Kidtal Can Promote Longitudinal Growth of Long Bone in Calcium-Deficient Adolescent Rats

  • Haosheng Xie,
  • Mingxuan Zhang,
  • Zhengyuan Zhou,
  • Hongyang Guan and ,
  • Kunmei Shan,
  • Shiwei Mi,
  • Xinfa Ye,
  • Zhihui Liu,
  • Jun Yin and
  • Na Han
  • + 5 authors+ 0 author

10 June 2025

Objective: Growth retardation in adolescents caused by nutritional deficiency requires effective intervention. A novel dietary supplement containing bamboo shoot extract, amino acids, and calcium citrate (Kidtal + Ca, KDTCa) was evaluated for its gro...

(This article belongs to the Section Micronutrients and Human Health)
  • Review
  • Open Access
11 Citations
6,138 Views
49 Pages

Harnessing Dietary Tryptophan: Bridging the Gap Between Neurobiology and Psychiatry in Depression Management

  • Amanda Chabrour Chehadi,
  • Enzo Pereira de Lima,
  • Cláudia Rucco Penteado Detregiachi,
  • Rafael Santos de Argollo Haber and ,
  • Virgínia Maria Cavallari Strozze Catharin,
  • Lucas Fornari Laurindo,
  • Vitor Engracia Valenti,
  • Cristiano Machado Galhardi,
  • Masaru Tanaka and
  • Sandra Maria Barbalho
  • + 5 authors+ 0 author

Major depressive disorder remains a leading cause of disability worldwide, with conventional antidepressants offering incomplete and often transient relief. Mounting evidence highlights disturbances in tryptophan (Trp) metabolism as a key biological...

(This article belongs to the Special Issue New Insights into Tryptophan Metabolism)
  • Article
  • Open Access
114 Views
32 Pages

Concurrent Changes in Facial Skin Parameters, Sleep, and the Salivary Melatonin Day–Night Difference During Topical Use of a Clock-Oriented Six-Botanical Formulation: An Exploratory 4-Week, Single-Arm Pilot Study

  • Miji Yeom,
  • Youngsu Jang,
  • Kyungeun Jeon,
  • Yoon Ji Jeong and ,
  • Soeun Cho,
  • Heetae Kim,
  • Sunhong Moon,
  • De-Hun Ryu,
  • Eunae Cho and
  • Eunsun Jung
  • + 6 authors+ 1 author

4 November 2026

Insufficient sleep can disrupt circadian organization and adversely affect skin condition. Perturbation of the cutaneous clock, which governs skin homeostasis, may contribute to this deterioration. In our study, a six-botanical mixture extract increa...

(This article belongs to the Section Cosmetic Dermatology)
  • Article
  • Open Access
1,637 Views
19 Pages

Lysimachia christinae Hance Extract Mitigates Kidney Stone Formation: Association with NOX2/ROS Axis Modulation and Ferroptosis

  • Lian Xia,
  • Zhaoguo Zhou,
  • Chen Luo,
  • Yan Yang and ,
  • Daike Zou,
  • Hanyue Zhang,
  • Kaizhi Hu and
  • Xianqin Luo
  • + 3 authors+ 0 author

Kidney stone disease is a common urinary system disorder with a continuously rising global incidence, posing a major public health challenge. As a classic traditional Chinese medicine for the treatment of kidney stones, Lysimachia christinae Hance (L...

(This article belongs to the Special Issue Molecular Mechanisms and Treatment of Kidney Diseases)
  • Article
  • Open Access
548 Views
26 Pages

30 August 2026

Metabolic syndrome, driven by obesity, poses a significant global health burden. P. incarnata leaf polyphenol extract (PP), a crude 70% ethanol extract, exhibits potential bioactive properties, yet its efficacy and underlying mechanisms against metab...

(This article belongs to the Topic Bioactive Compounds from Agricultural and Agro-Industrial By-Products: Recovery, Characterization, and Health-Promoting Applications)

of 24