Topic Editors

1. Faculty of Agricultural, Environmental and Food Sciences, Free University of Bozen-Bolzano, 39100 Bolzano, Italy
2. ICOFF, International Competence Centre on Food Fermentations, Free University of Bozen-Bolzano, 39100 Bolzano, Italy
Dr. Edoardo Longo
Faculty of Agricultural, Environmental and Food Sciences, Free University of Bozen-Bolzano, 39100 Bolzano, Italy
Dr. Alberto Ceccon
Laimburg Research Center, 39100 Bolzano, Italy

Bioactive Compounds from Agricultural and Agro-Industrial By-Products: Recovery, Characterization, and Health-Promoting Applications

Abstract submission deadline
28 February 2027
Manuscript submission deadline
31 May 2027
Viewed by
941

Topic Information

Dear Colleagues,

Agricultural and agro-industrial by-products represent a vast and underutilized source of bioactive natural products, including polyphenols, carotenoids, peptides, dietary fibers, and other phytochemicals with potentially high added value. Their sustainable recovery and valorization offer innovative opportunities to develop functional ingredients, nutraceuticals, and food products with potential health-promoting effects.

The growing interest in natural bioactive materials is driven by their documented antioxidant, anti-inflammatory, metabolic, and disease-preventive properties. Compounds extracted from agricultural and agro-industrial residues have shown promising biological activities that may support human health across multiple domains, including cardiometabolic health, gut health, immune function, cognitive performance, and healthy aging.

With this topic, we aim to highlight multidisciplinary research integrating food science and technology, analytical chemistry, metabolomics, sensory science, and biomedical approaches to explore the recovery, characterization, formulation, and biological effects of bioactive compounds from agricultural and agro-industrial by-products. Particular emphasis is placed on sustainable and green extraction technologies, as well as on state-of-the-art analytical tools (e.g., LC–MS/MS, HRMS, NMR, metabolomics, chemometrics) for compound profiling, authentication, and biomarker discovery.

Contributions addressing the development of functional foods, nutraceuticals, and novel ingredients—including stabilization, encapsulation, and formulation strategies—are strongly encouraged. Studies on sensory quality, consumer perception, and product acceptance are also welcome, as they are essential for the successful market implementation of sustainable bioactive products.

Both in vitro and in vivo investigations, as well as clinical and nutritional studies, are invited to elucidate the mechanisms of action and health-promoting potential of bioactive compounds derived from agricultural sources.

This Topic aligns with current European and international priorities on sustainability, circular bioeconomy, and health promotion, including large-scale initiatives such as the ERDF (EFRE–FESR) ZeroResidue project, which focuses on the valorization of agricultural and agro-industrial by-products through advanced extraction technologies and the development of high-value bioactive compounds.

Dr. Emanuele Boselli
Dr. Edoardo Longo
Dr. Alberto Ceccon
Topic Editors

Keywords

  • agricultural by-products
  • agro-industrial by-products
  • circular bioeconomy
  • bioactive compounds
  • green technologies
  • chemometrics
  • food formulations
  • nutraceuticals
  • sensory analysis
  • metabolomics
  • ZeroResidue ERDF
  • healthy aging
  • food authentication
  • phytochemicals
  • food fermentations

Participating Journals

Journal Name Impact Factor CiteScore Launched Year First Decision (median) APC
Analytica
analytica
3.6 3.7 2020 19 Days CHF 1200 Submit
Antioxidants
antioxidants
6.6 12.4 2012 18.7 Days CHF 2900 Submit
AppliedChem
appliedchem
- 2.9 2021 20.9 Days CHF 1200 Submit
Chemistry
chemistry
2.4 3.9 2019 15 Days CHF 1800 Submit
Foods
foods
5.1 8.7 2012 15 Days CHF 2900 Submit
Metabolites
metabolites
3.7 6.9 2011 16.7 Days CHF 2700 Submit
Molecules
molecules
4.6 8.6 1996 15.1 Days CHF 2700 Submit
Nutrients
nutrients
5.0 9.1 2009 15 Days CHF 2900 Submit

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Published Papers (1 paper)

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16 pages, 1616 KB  
Article
Changes in Active Components, Antioxidant Activity and Alcohol Dehydrogenase Activity of Penthorum chinense Pursh at Different Harvest Times
by Zhuoya Xiang, Hongchun Liang, Qian Lai, Junlin Deng, Lu Gan, Yongqing Zhu, Yinghao Yuan, Chen Xia and Manyou Yu
Foods 2026, 15(8), 1371; https://doi.org/10.3390/foods15081371 - 15 Apr 2026
Viewed by 375
Abstract
This study aims to establish a time-resolved harvesting standard for Penthorum chinense. To achieve this, we systematically integrated growth phenology, phytochemical accumulation dynamics, and antioxidant activity across six key developmental stages. The contents of total phenolics, flavonoids, proanthocyanidins, and tannins exhibited a [...] Read more.
This study aims to establish a time-resolved harvesting standard for Penthorum chinense. To achieve this, we systematically integrated growth phenology, phytochemical accumulation dynamics, and antioxidant activity across six key developmental stages. The contents of total phenolics, flavonoids, proanthocyanidins, and tannins exhibited a biphasic fluctuation pattern, which was closely correlated with variations in antioxidant capacity. Principal component analysis identified the optimal harvest windows: flowers achieved the highest integrated score at the full blooming stage, whereas leaves scored highest at the early fruiting stage. These periods also corresponded with greater fresh biomass, supporting favorable economic returns. Accordingly, we recommend the full blooming stage as the optimal harvest time for flowers and the early fruiting stage for leaves and stems. Future research should focus on elucidating how environmental factors regulate the accumulation of bioactive compounds, which will further refine cultivation and harvest strategies to enhance the quality of this medicinal herb. Full article
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