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Lifestyle, Diet, Wine and Health

A special issue of Nutrients (ISSN 2072-6643). This special issue belongs to the section "Nutrition and Public Health".

Deadline for manuscript submissions: 5 July 2026 | Viewed by 104

Special Issue Editors


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Guest Editor
Consorci Sanitari Integral, University of Barcelona, Barcelona, Spain
Interests: cardiovascular disease; heart failure; acute cardiovascular care

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Guest Editor
Department of Internal Medicine, Institut d'Investigacions Biomèdiques August Pi Sunyer (IDIBAPS), Hospital Clinic, University of Barcelona, Barcelona, Spain
Interests: mediterranean diet; nutrition; wine; olive oil; nuts; cardiovascular disease; stroke; cancer; hypertension; metabolic syndrome; diabetes; blood pressure; echocardiography; heart failure; abdominal obesity; lipoproteins

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Guest Editor
Unit of Digestive Trait Endoscopy, CDI (Centro Diagnostico Italiano), Milan, Italy
Interests: gastroenterology; tumors and precancers of the digestive system; Crohn's disease; ulcerative colitis; celiac disease; diverticulosis; hiatal hernia and gastroesophageal reflux disease; constipation and diarrhea; oncology; clinical nutrition
Special Issues, Collections and Topics in MDPI journals

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Guest Editor Assistant
Deutsche Weinakademie, Bodenheim, Germany
Interests: diet; nutrition; wine & health

Special Issue Information

Dear Colleagues,

The role of moderate wine consumption in a healthy diet and lifestyle remains uncertain. Recent studies question the existence of the J-curve, which suggests lower risk at low-to-moderate wine consumption and higher risk at higher amounts. They imply that there may be no safe level of wine consumption. Few studies have differentiated between types of alcoholic beverages, examined drinking patterns, or considered diet and other lifestyle factors. Although alcohol is a carcinogen, wine also contains substantial amounts of bioactive compounds, known as polyphenols, with antioxidant and anti-inflammatory effects, which produce multiple beneficial biological effects on the body. Scientific evidence shows that moderate wine and other alcoholic beverage consumption is one of several lifestyle factors, alongside not smoking, maintaining a healthy diet, engaging in regular physical activity, and avoiding being overweight, that are linked to longer life expectancy, a lower incidence of chronic diseases, and better physical and mental health.

The influence of lifestyle factors, drinking and dietary patterns, and beverage-specific components on health risks and longevity has been a key topic at the first and second Lifestyle, Diet, Wine and Health Congresses. Leading international experts presented the latest scientific evidence on moderate wine consumption and lifestyle factors that can promote healthy ageing and extend life expectancy.

This Special Issue of Nutrients aims to summarise the latest scientific evidence presented at both congresses, focusing on the role of moderate wine consumption within the Mediterranean diet, its bioactive ingredients, consumption patterns, interaction with other dietary and lifestyle factors, and the associated health outcomes.

We invite original articles, reviews and short communications.

Dr. Josep Masip
Prof. Dr. Ramón Estruch
Prof. Dr. Attilio Giacosa
Guest Editors

Ursula Fradera
Guest Editor Assistant

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 250 words) can be sent to the Editorial Office for assessment.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Nutrients is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2900 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • wine
  • alcohol
  • mediterranean diet
  • polyphenols
  • cardiovascular disease
  • lifestyle factors
  • diabetes
  • anti-oxidants
  • longevity

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Published Papers (1 paper)

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9 pages, 195 KB  
Viewpoint
The Unfinished Debate on Wine and Other Alcoholic Beverages: Conflicting Evidence, Public Health Messages and the Missing Trial
by Miguel Angel Alvarez-Mon, Diego Martínez-Urbistondo, María Barbería-Latasa, Zenaida Vázquez-Ruiz, Miguel Ruiz-Canela, Maira Bes-Rastrollo and Miguel Ángel Martínez-González
Nutrients 2026, 18(3), 529; https://doi.org/10.3390/nu18030529 - 5 Feb 2026
Abstract
The overall health impact of alcohol remains controversial. The Global Burden of Disease (GBD) study made headlines in 2018 by stating that zero alcohol was the safest option. However, its 2022 update introduced age-specific adaptations, asserting that moderate drinking may offer net benefits [...] Read more.
The overall health impact of alcohol remains controversial. The Global Burden of Disease (GBD) study made headlines in 2018 by stating that zero alcohol was the safest option. However, its 2022 update introduced age-specific adaptations, asserting that moderate drinking may offer net benefits in some populations. The 2025 U.S. Surgeon General report also discouraged any alcohol intake because of associated cancer risks, but a simultaneous report by the National Academies emphasized tailoring recommendations to individual risks. Mendelian randomization (MR) studies found no health benefits and highlighted increased risks—even at low alcohol doses—challenging dozens of conventional epidemiologic findings in large observational cohorts, some of them of high methodological quality. Given these contradictions, there is a pressing need for large randomized controlled trials in drinkers promoting cessation versus moderation. While small trials have shown some metabolic and cardiovascular benefits of moderate red wine consumption, no large-scale randomized trial has yet assessed hard clinical outcomes comprehensively. Without such evidence, debates will persist. Current guidelines appropriately discourage alcohol in certain populations, but generalizations such as “no safe level of alcohol” might lack sufficient empirical support and perhaps they need a tailored and practical strategy in the context of precision medicine. A balanced, evidence-based approach—free from bias, independent of the industry and grounded in rigorous research—is essential for informed public health policy decisions. Full article
(This article belongs to the Special Issue Lifestyle, Diet, Wine and Health)
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