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7,951 Results Found

  • Article
  • Open Access
11 Citations
9,722 Views
10 Pages

A Low Power Low Phase Noise Oscillator for MICS Transceivers

  • Dawei Li,
  • Dongsheng Liu,
  • Chaojian Kang and
  • Xuecheng Zou

12 January 2017

A low-power, low-phase-noise quadrature oscillator for Medical Implantable Communications Service (MICS) transceivers is presented. The proposed quadrature oscillator generates 349~689 MHz I/Q (In-phase and Quadrature) signals covering the MICS band....

(This article belongs to the Special Issue Smart Sensor Interface Circuits and Systems)
  • Review
  • Open Access
202 Views
30 Pages

Brassica spp. and Antimicrobial Power: A Review of MICs of Their Plant Extracts

  • Angel Montero Lage,
  • Alexandre Lamas Freire,
  • Emiliano J. Quinto,
  • Carlos M. Franco and
  • Beatriz I. Vázquez

27 October 2026

Background/Objectives: Brassica spp. constitute an important group of edible plants. Over the last century, the important power of these plants as bioactive producers with anticancer, anti-inflammatory, antioxidant or cardioprotective properties has...

(This article belongs to the Special Issue Natural Compounds as Antimicrobial Agents, 3rd Edition)
  • Article
  • Open Access
17 Citations
4,098 Views
13 Pages

26 October 2022

An implantable stacked planar inverted-F antenna (PIFA) for biotelemetric communication in the 402–405 MHz Medical Implant Communications Service (MICS) frequency band is designed and fabricated. With the proposed PIFA structure, a slot on each...

(This article belongs to the Section Physical Sensors)
  • Article
  • Open Access
10 Citations
3,302 Views
17 Pages

Background: Antibiotics at sub-inhibitory concentrations can rewire bacterial regulatory networks, impacting virulence. Objective: The way that exposure to selected antibiotics (ciprofloxacin, amikacin, azithromycin, ceftazidime, and meropenem) below...

(This article belongs to the Special Issue Advancing and Standardising Antimicrobial Susceptibility and Resistance Detection Methodology)
  • Article
  • Open Access
9 Citations
8,838 Views
18 Pages

Outcomes of Elongated Styloid Process Syndrome Treated with Minimally Invasive Cervical Styloidectomy (MICS)—A Single-Center Retrospective Study

  • Jakub Bargiel,
  • Michał Gontarz,
  • Krzysztof Gąsiorowski,
  • Tomasz Marecik and
  • Grażyna Wyszyńska-Pawelec

25 October 2024

Background: Stylohyoid syndrome, also known as classical Eagle syndrome (ES), is a rare condition characterized by elongation of the styloid process (SP) or calcification of the stylohyoid chain, presenting numerous non-specific symptoms. Most papers...

(This article belongs to the Section Dentistry, Oral Surgery and Oral Medicine)
  • Article
  • Open Access
3 Citations
1,826 Views
12 Pages

Development of an Immunochromatographic Test with Recombinant MIC2-MIC3 Fusion Protein for Serological Detection of Toxoplasma gondii

  • Jianzhong Wang,
  • Yi Zhao,
  • Jicheng Qiu,
  • Jing Liu and ,
  • Rui Zhou,
  • Xialin Ma,
  • Xiaojie Wu,
  • Xiaoguang Li,
  • Wei Mao and
  • Heng Zhang
  • + 6 authors+ 1 author

Toxoplasma gondii is a globally significant zoonotic pathogen responsible for severe parasitic diseases in humans and animals. This study aimed to design, develop, and evaluate a novel immunochromatographic test (ICT) using a recombinant MIC2-MIC3 fu...

(This article belongs to the Section Veterinary Microbiology, Parasitology and Immunology)
  • Article
  • Open Access
1 Citations
1,353 Views
9 Pages

Background: Minimally invasive off-pump coronary artery bypass grafting (MICS-OPCAB) offers potential advantages over conventional sternotomy, including reduced trauma and faster recovery. This study evaluates the safety and feasibility of MICS-OPCAB...

(This article belongs to the Special Issue New Advances in Minimally Invasive Coronary Surgery)
  • Communication
  • Open Access
5 Citations
3,590 Views
11 Pages

1 July 2021

The enteric human adenoviruses of species F (HAdVs-F), which comprise HAdV-F40 and HAdV-F41, are significant pathogens that cause acute gastroenteritis in children worldwide. The early transcription unit 3 (E3) of HAdVs-F is markedly different from t...

(This article belongs to the Special Issue Adenovirus Cell and Immune Interactions)
  • Article
  • Open Access
3 Citations
2,807 Views
12 Pages

Circulatory MIC-1 as a Determinant of Prostate Cancer Racial Disparity

  • Dev Karan,
  • Jo Wick,
  • Seema Dubey,
  • Ossama Tawfik and
  • Peter Van Veldhuizen

18 October 2020

In this study, we investigated the potential of MIC-1 (macrophage inhibitory cytokine-1) on the severity of prostate cancer between African American men and Caucasians. Differences between the races were examined using Mann–Whitney tests for co...

  • Article
  • Open Access
12 Citations
5,699 Views
15 Pages

Predicting Salmonella MIC and Deciphering Genomic Determinants of Antibiotic Resistance and Susceptibility

  • Moses B. Ayoola,
  • Athish Ram Das,
  • B. Santhana Krishnan,
  • David R. Smith and ,
  • Bindu Nanduri and
  • Mahalingam Ramkumar
  • + 1 author+ 0 author

Salmonella spp., a leading cause of foodborne illness, is a formidable global menace due to escalating antimicrobial resistance (AMR). The evaluation of minimum inhibitory concentration (MIC) for antimicrobials is critical for characterizing AMR. The...

(This article belongs to the Section Food Microbiology)
  • Article
  • Open Access
32 Citations
12,856 Views
11 Pages

The assessment of minimum inhibitory concentration (MIC) is a conventional technique used for the screening of microbial resistance against antibiotics, biocides, and contaminants such as heavy metals. However, as part of our ongoing work, we have ob...

  • Article
  • Open Access
8 Citations
2,907 Views
22 Pages

MIC19 Exerts Neuroprotective Role via Maintaining the Mitochondrial Structure in a Rat Model of Intracerebral Hemorrhage

  • Siyuan Yang,
  • Xulong Yin,
  • Jiahe Wang,
  • Haiying Li and ,
  • Haitao Shen,
  • Qing Sun and
  • Xiang Li
  • + 2 authors+ 0 author

As an essential constituent of the mitochondrial contact site and cristae organization system (MICOS), MIC19 plays a crucial role in maintaining the stability of mitochondrial function and microstructure. However, the mechanisms and functions of MIC1...

(This article belongs to the Special Issue Trends in Neuroscience: From Molecular Mechanisms to Innovative Therapeutics)
  • Article
  • Open Access
231 Views
19 Pages

Background/Objectives: Antigen-specific adoptive CD8+ T-cell therapy has demonstrated promising clinical activity in selected cancers; however, its broader efficacy against solid tumors remains limited by the immunosuppressive tumor microenvironment...

(This article belongs to the Section Immunology and Immunotherapy)
  • Article
  • Open Access
6 Citations
5,660 Views
11 Pages

On-chip MIC by Combining Concentration Gradient Generator and Flanged Chamber Arrays

  • Xiao-Yan Zhang,
  • Zhe-Yu Li,
  • Kose Ueno,
  • Hiroaki Misawa and ,
  • Nan-Qi Ren and
  • Kai Sun
  • + 1 author+ 0 author

17 February 2020

Minimum inhibition concentration (MIC) of antibiotic is an effective value to ascertain the agent and minimum dosage of inhibiting bacterial growth. However, current techniques to determine MIC are labor intensive and time-consuming, and require skil...

(This article belongs to the Collection Lab-on-a-Chip)
  • Article
  • Open Access
8 Citations
4,767 Views
10 Pages

Effects of Aging on Expression of Mic60 and OPA1 and Mitochondrial Morphology in Myocardium of Tibetan Sheep

  • Guan Wang,
  • Yuzhu Luo,
  • Jiang Hu,
  • Jiqing Wang and ,
  • Xiu Liu and
  • Shaobin Li
  • + 1 author+ 0 author

20 November 2020

In order to investigate the effects of aging on the expression of Mic60 and OPA1 and mitochondrial morphology in plateau animals, the expression of Mic60 and OPA1 genes and proteins, and the morphology of mitochondria in the myocardium of adult and a...

(This article belongs to the Special Issue Immunohistochemical and Physiological Research on Farm Animals)
  • Article
  • Open Access
36 Citations
4,729 Views
12 Pages

Vancomycin is an antibiotic commonly used for the treatment of enterococcal infections. However, there is no clear correlation regarding of vancomycin area under the curve/minimum inhibitory concentration (AUC/MIC) ratio and clinical outcomes for the...

(This article belongs to the Special Issue Therapeutic Drug Monitoring as a Useful Tool in Therapy Improvement)
  • Communication
  • Open Access
6 Citations
6,398 Views
6 Pages

Discrepancy in Vancomycin AUC/MIC Ratio Targeted Attainment Based upon the Susceptibility Testing in Staphylococcus aureus

  • Seenae Eum,
  • Robert L. Bergsbaken,
  • Craig L. Harvey,
  • J. Bryan Warren and
  • John C. Rotschafer

This study demonstrated a statistically significant difference in vancomycin minimum inhibitory concentration (MIC) for Staphylococcus aureus between a common automated system (Vitek 2) and the E-test method in patients with S. aureus bloodstream inf...

  • Article
  • Open Access
613 Views
18 Pages

Robust Fitting Polarization Curves of X70 Steel Under MIC and AC Interference

  • Shouxin Zhang,
  • Yingfan Cheng,
  • Yuanyu Wang,
  • Junfei Zheng and ,
  • Huizhong Xu,
  • Bingyuan Hong,
  • Daiwei Liu,
  • Zhiwei Chen and
  • Baikang Zhu
  • + 4 authors+ 0 author

3 March 2026

Extracting reliable corrosion kinetic parameters from polarization curves is particularly challenging for X70 steel under the synergistic effect of microbiologically influenced corrosion (MIC) and alternating current (AC) interference, as both factor...

  • Article
  • Open Access
10 Citations
3,680 Views
15 Pages

EUCAST Ibrexafungerp MICs and Wild-Type Upper Limits for Contemporary Danish Yeast Isolates

  • Karin M. Jørgensen,
  • Karen M. T. Astvad,
  • Rasmus K. Hare and
  • Maiken C. Arendrup

20 October 2022

Ibrexafungerp is a novel triterpenoid antifungal that inhibits glucan synthase and thus fungal cell wall synthesis. We examined the in vitro activity against contemporary clinical yeast, investigated inter-laboratory and intra-laboratory variability,...

(This article belongs to the Section Fungal Pathogenesis and Disease Control)
  • Article
  • Open Access
820 Views
15 Pages

Real-World Comparison of Trough- and Online-Bayesian-Calculator-Derived AUC0–24/MIC Target Attainment for Vancomycin Monitoring in Critically Ill Patients

  • Sufyan Alomair,
  • Zahra Alsultan,
  • Fatimah Alsultan,
  • Fatimah Alghadeer and ,
  • Alzahraa Aljafar,
  • Anas Alkhawaldeh,
  • Ayat Alherz and
  • Batool Alhassan
  • + 3 authors+ 0 author

18 July 2026

Introduction: The preferred PK/PD goal for vancomycin is now AUC0–24/MIC-guided dosing, which requires two blood samples, additional time, increased cost, and possibly specialized staff, potentially limiting its use. Our study compared vancomyc...

(This article belongs to the Special Issue Innovative Tools for Drug Analysis and Therapeutic Drug Monitoring (TDM): 2nd Edition)
  • Article
  • Open Access
648 Views
18 Pages

Disruption of Fructose 1,6-Bisphosphatase 2 Proximity to MIC60 Correlates with Mitochondrial Ultrastructural Changes

  • Łukasz Pietras,
  • Marta Migocka-Patrzałek,
  • Bartosz Budziak,
  • Dariusz Rakus and
  • Agnieszka Gizak

20 May 2026

Fructose 1,6-bisphosphatase 2 (FBP2) is a multifunctional protein whose cellular functions depend on its oligomeric state. Forced FBP2 tetramerization has been linked to microtubule disruption and impaired mitochondrial trafficking, accompanied by ab...

(This article belongs to the Section Mitochondria)
  • Article
  • Open Access
230 Views
18 Pages

Network Analysis of Antimicrobial MIC Profiles Reveals Extensive Covariation in Chicken-Associated Escherichia coli from Large-Scale Breeding Flocks in Central Hungary

  • Ádám Kerek,
  • Gergely Álmos Tornyos,
  • Edit Szarka,
  • Levente Hunor Husz and ,
  • Máté Hetyésy,
  • László Kovács and
  • Ákos Jerzsele
  • + 2 authors+ 0 author

Background: The surveillance of non-clinical bacteria from food-producing animals can reveal antimicrobial selection patterns without conditioning sampling on clinical disease, but categorical resistance estimates are difficult to compare when organi...

(This article belongs to the Special Issue Antimicrobial Stewardship in Human and Veterinary Medicine)
  • Article
  • Open Access
2 Citations
1,790 Views
13 Pages

False Data Injection Attacks Detection Based on Stacking and MIC-DCXGB

  • Tong Li,
  • Tian Xia,
  • Haoming Zhang,
  • Dongyang Liu and ,
  • Hai Zhao and
  • Zhuolin Liu
  • + 1 author+ 0 author

7 November 2024

With the integration of sustainable energy, the power grid has become increasingly information-intensive and complex. To address the issue of power grid cyber-physical systems being unable to operate securely and stably when systems suffer false data...

(This article belongs to the Section Energy Sustainability)
  • Systematic Review
  • Open Access
551 Views
36 Pages

Bacteriocins for Safety of Animal-Derived Foods: Systematic Mapping, Multilevel MIC Analysis, Food-Matrix Applications, and Emerging Antiparasitic Evidence

  • Rosario De Fazio,
  • Pierluigi Aldo Di Ciccio,
  • Rosangela Odore,
  • Vincenzo Musella and ,
  • Paola Roncada and
  • Cristian Piras
  • + 1 author+ 0 author

9 October 2026

Foodborne bacterial hazards remain a major challenge for animal-derived food chains, whereas evidence for antiparasitic effects of bacteriocins is much smaller and mechanistically heterogeneous. This systematic review, reported in accordance with PRI...

(This article belongs to the Special Issue Pathogens in Foods in the One Health Approach: Identification, Risk Assessment, Management and Data Sharing)
  • Review
  • Open Access
488 Views
31 Pages

9 September 2026

The rise in carbapenem resistance is well documented, but a less conspicuous trend has received far less attention: the gradual upward shift in minimum inhibitory concentration (MIC) values among isolates that remain phenotypically “susceptible...

(This article belongs to the Special Issue Pharmacokinetic and Dosing Optimization of Antibiotics in Clinical Infections)
  • Article
  • Open Access
51 Citations
14,457 Views
16 Pages

29 January 2023

Construction is a major source of carbon emissions. Moreover, it faces various other sustainability challenges, such as construction waste, construction noise, vehicular traffic near construction sites, dust and other air and water pollutants, and sa...

(This article belongs to the Special Issue Smart and Digital Construction in AEC Industry)
  • Article
  • Open Access
5 Citations
3,285 Views
10 Pages

The Rapid Phenotypic Susceptibility Testing in Real-Life Experience: How the MIC Values Impact on Sepsis Fast Diagnostic Workflow

  • Giuseppe Migliorisi,
  • Maddalena Calvo,
  • Antonina Collura,
  • Francesca Di Bernardo and ,
  • Marianna Perez,
  • Guido Scalia and
  • Stefania Stefani
  • + 2 authors+ 0 author

The MIC value definition faithfully reflects antimicrobial sensitivity, profoundly impacting the infection's clinical outcome. Our study aimed to evaluate the Accelerate PhenoTM System in defining the importance of fast phenotypic susceptibility data...

(This article belongs to the Special Issue Laboratory Diagnosis in Microbial Diseases, 2nd Edition)
  • Communication
  • Open Access
7 Citations
3,626 Views
16 Pages

4 June 2021

In light of the growth in demand for multiband antennas for medical applications, this research proposes a MICS/ISM meander-line microstrip antenna encapsulated in an oblong-shaped pod for use in diagnoses of the gastrointestinal tract. The proposed...

(This article belongs to the Section Physical Sensors)
  • Article
  • Open Access
2 Citations
1,479 Views
12 Pages

15 August 2025

Background: Toxoplasma gondii (T. gondii) infection causes serious diseases in immunocompromised patients and causes congenital toxoplasmosis in infants. T. gondii microneme protein 8 (MIC8) and apical membrane antigen 1 (AMA1) are essential pro...

(This article belongs to the Special Issue Virus-Like Particle Vaccine Development)
  • Review
  • Open Access
3 Citations
3,792 Views
28 Pages

Rapid Antimicrobial Susceptibility Testing (AST): Overview of New Commercially Available Automated Phenotypic Tools for Minimum Inhibitory Concentration (MIC) Determination

  • Giorgia Piccinini,
  • Antonio Curtoni,
  • Alessandro Bondi,
  • Mattia Genco and ,
  • Fabio Longo,
  • Carlotta Polizzi,
  • Paolo Valesella,
  • Silvia Corcione,
  • Francesco Giuseppe De Rosa and
  • Cristina Costa
  • + 5 authors+ 0 author

Antimicrobial resistance (AMR) represents one of the most urgent global health threats, significantly impacting patient outcomes, healthcare systems, and economic sustainability. Rapid and accurate antimicrobial susceptibility testing (AST) are essen...

(This article belongs to the Special Issue Antimicrobial Resistance: From Surveillance to New Therapies)
  • Review
  • Open Access
74 Citations
20,307 Views
19 Pages

17 October 2018

Pyrrole and its polysubstituted derivatives are important five-membered heterocyclic compounds, which exist alone or as a core framework in many pharmaceutical and natural product structures, some of which have good biological activities. The Van Leu...

(This article belongs to the Collection Heterocyclic Compounds)
  • Article
  • Open Access
9 Citations
4,117 Views
7 Pages

Do Candida albicans Isolates with Borderline Resistant Micafungin MICs Always Harbor FKS1 Hot Spot Mutations?

  • Kathrin Spettel,
  • Sonia Galazka,
  • Richard Kriz,
  • Iris Camp and
  • Birgit Willinger

28 January 2021

Antifungal susceptibility testing is important in guiding patient therapy due to an increasing number of resistant Candida isolates. In the clinical strain collection of the Austrian resistance report (AURES), a high number of micafungin-resistant C....

(This article belongs to the Special Issue Epidemiology, Diagnosis of Fungal Infections)
  • Article
  • Open Access
23 Citations
7,929 Views
23 Pages

6 September 2022

In recent years, the performance of free-and-open-source software (FOSS) for image processing has significantly increased. This trend, as well as technological advancements in the unmanned aerial vehicle (UAV) industry, have opened blue skies for bot...

(This article belongs to the Special Issue Unconventional Drone-Based Surveying)
  • Article
  • Open Access
10 Citations
4,482 Views
11 Pages

25 January 2025

Cutaneous fungal infections represent a significant burden worldwide with a high impact on public health. Accurate identification of dermatophyte species causing these infections is vital for an appropriate treatment. Terbinafine is the primary agent...

(This article belongs to the Special Issue An Update on Fungal Infections)
  • Communication
  • Open Access
11 Citations
3,806 Views
6 Pages

The Emergence of Echinocandin-Resistant Candida glabrata Exhibiting High MICs and Related FKS Mutations in Turkey

  • Ali Korhan Sig,
  • Meliha Cagla Sonmezer,
  • Dolunay Gülmez,
  • Serhat Duyan and ,
  • Ömrüm Uzun and
  • Sevtap Arikan-Akdagli
  • + 1 author+ 0 author

26 August 2021

The frequency of invasive fungal infections shows a rising trend as well as a high morbidity and mortality. Among the causative agents, a shift toward the non-albicans Candida species including Candida glabrata species complex is being observed in se...

(This article belongs to the Special Issue Antifungal Resistance)
  • Article
  • Open Access
2 Citations
1,670 Views
19 Pages

Genotype–Phenotype Links Between Aminoglycoside-Modifying Enzymes and Aminoglycoside MICs in Aminoglycoside-Resistant Klebsiella pneumoniae in a Southern Vietnam Tertiary Hospital

  • Tuan Huu Ngoc Nguyen,
  • Huy Quang Nguyen,
  • Tham Thi Hong Ho,
  • Hung Cao Dinh and ,
  • Huong Thi Nguyen,
  • Tam Bui Thanh Pham and
  • Ha Minh Nguyen
  • + 2 authors+ 0 author

Aminoglycosides remain important components of combination therapy for complicated Klebsiella pneumoniae infections in Vietnam; however, gene-level evidence linking aminoglycoside-modifying enzymes (AMEs) with minimum inhibitory concentrations (MICs)...

(This article belongs to the Special Issue Advances in Clinical Infections and Antimicrobial Resistance)
  • Article
  • Open Access
16 Citations
6,657 Views
29 Pages

21 December 2021

Accurate quality prediction can find and eliminate quality hazards. It is difficult to construct an accurate quality mathematical model for the production of small samples with high dimensionality due to the influence of quality characteristics and t...

(This article belongs to the Special Issue Smart Service Technology for Industrial Applications)
  • Article
  • Open Access
14 Citations
6,491 Views
35 Pages

Laboratory Assessment for Determining Microplastics in Freshwater Systems—Characterization and Identification along the Somesul Mic River

  • Stefania Gheorghe,
  • Catalina Stoica,
  • Anca Maria Harabagiu,
  • Dorian-Gabriel Neidoni and ,
  • Emanuel Daniel Mighiu,
  • Costel Bumbac,
  • Ioana Alexandra Ionescu,
  • Aida Pantazi,
  • Laura-Bianca Enache and
  • Marius Enachescu
  • + 5 authors+ 0 author

9 January 2024

Microplastics (MPs) pollution has become a persisting problem over the last decades and is a critical issue for environmental protection and human health. In this context, scientific data able to reveal MPs presence and improve the characterization a...

(This article belongs to the Section Water Quality and Contamination)
  • Article
  • Open Access
3 Citations
2,395 Views
21 Pages

Optimizing Low-Cost Gas Analysis with a 3D Printed Column and MiCS-6814 Sensor for Volatile Compound Detection

  • Nela Skowronkova,
  • Martin Adamek,
  • Magdalena Zvonkova,
  • Jiri Matyas and ,
  • Anna Adamkova,
  • Stepan Dlabaja,
  • Martin Buran,
  • Veronika Sevcikova,
  • Jiri Mlcek and
  • Martina Cernekova
  • + 6 authors+ 1 author

13 October 2024

This paper explores an application of 3D printing technology on the food industry. Since its inception in the 1980s, 3D printing has experienced a huge rise in popularity. This study uses cost-effective, flexible, and sustainable components that enab...

(This article belongs to the Special Issue Gas Recognition in E-Nose System)
  • Article
  • Open Access
17 Citations
3,831 Views
15 Pages

31 December 2019

We derived a closed-form expression of the maximum power transfer efficiency (MPTE) between a transmitting antenna inside the brain and a receiving antenna outside the head using spherical wave expansion. The derived expression was validated using a...

(This article belongs to the Special Issue Wireless Body Area Networks: Applications and Technologies)
  • Article
  • Open Access
24 Citations
5,105 Views
17 Pages

Improving Bearing Fault Diagnosis Using Maximum Information Coefficient Based Feature Selection

  • Xianghong Tang,
  • Jiachen Wang,
  • Jianguang Lu,
  • Guokai Liu and
  • Jiadui Chen

2 November 2018

Effective feature selection can help improve the classification performance in bearing fault diagnosis. This paper proposes a novel feature selection method based on bearing fault diagnosis called Feature-to-Feature and Feature-to-Category- Maximum I...

(This article belongs to the Special Issue Fault Detection and Diagnosis in Mechatronics Systems)
  • Article
  • Open Access
1 Citations
755 Views
26 Pages

3 April 2026

This study proposes a data-driven framework with post hoc interpretability analysis for one-step-ahead crystal diameter prediction in the Czochralski (CZ) silicon single-crystal growth process. To address the strong multivariable coupling, nonlinear...

(This article belongs to the Section AI-Enabled Process Engineering)
  • Article
  • Open Access
10 Citations
4,567 Views
12 Pages

Meropenem MICs at Standard and High Inocula and Mutant Prevention Concentration Inter-Relations: Comparative Study with Non-Carbapenemase-Producing and OXA-48-, KPC- and NDM-Producing Klebsiella pneumoniae

  • Maria V. Golikova,
  • Elena N. Strukova,
  • Kamilla N. Alieva,
  • Vladimir A. Ageevets and ,
  • Alisa A. Avdeeva,
  • Ofeliia S. Sulian and
  • Stephen H. Zinner
  • + 2 authors+ 0 author

The minimal inhibitory concentration (MIC) is conventionally used to define in vitro levels of susceptibility or resistance of a specific bacterial strain to an antibiotic and to predict its clinical efficacy. Along with MIC, other measures of bacter...

(This article belongs to the Section Mechanism and Evolution of Antibiotic Resistance)
  • Article
  • Open Access
2 Citations
879 Views
12 Pages

Oritavancin Multiple Dosing for Complex Infections: A Pharmacokinetic/Pharmacodynamic Simulation Study

  • Ana Alarcia-Lacalle,
  • Miguel Ángel Morán-Rodríguez,
  • Laura Morata,
  • Arantxa Isla and ,
  • Andrés Canut-Blasco and
  • Alicia Rodríguez-Gascón
  • + 1 author+ 0 author

Background/Objectives: Oritavancin therapy for complex infections remains challenging due to the lack of well-established dosing regimens. The objective of this work was to apply PK/PD modeling and Monte Carlo simulation considering different PK/PD t...

(This article belongs to the Special Issue Clinical Pharmacokinetics and Pharmacodynamics of Antimicrobial Therapy)
  • Article
  • Open Access
13 Citations
5,376 Views
13 Pages

Pharmacokinetics and Pharmacodynamics of Florfenicol in Plasma and Synovial Fluid of Pigs at a Dose of 30 mg/kgbw Following Intramuscular Administration

  • Zoltán Somogyi,
  • Patrik Mag,
  • Réka Simon,
  • Ádám Kerek and ,
  • Pál Szabó,
  • Ervin Albert,
  • Imre Biksi and
  • Ákos Jerzsele
  • + 3 authors+ 0 author

A major problem of our time is the ever-increasing resistance to antimicrobial agents in bacterial populations. One of the most effective ways to prevent these problems is to target antibacterial therapies for specific diseases. In this study, we inv...

(This article belongs to the Special Issue Epidemiology, Impact and Mitigation of Antimicrobial Resistance in Veterinary Medicine, 2nd Edition)
  • Article
  • Open Access
2 Citations
4,607 Views
15 Pages

15 October 2025

Background: Candida albicans infects most reproductive-aged women, causing a prevalent infection known as Vulvovaginal Candida. As there has been an increase in resistance to widely used antifungal agents, particularly fluconazole, used in infec...

(This article belongs to the Section Pharmacology)
  • Article
  • Open Access
13 Citations
5,498 Views
20 Pages

Receptor Heterodimerization and Co-Receptor Engagement in TLR2 Activation Induced by MIC1 and MIC4 from Toxoplasma gondii

  • Flávia Costa Mendonça-Natividade,
  • Carla Duque Lopes,
  • Rafael Ricci-Azevedo,
  • Aline Sardinha-Silva and ,
  • Camila Figueiredo Pinzan,
  • Ana Claudia Paiva Alegre-Maller,
  • Lilian L. Nohara,
  • Alan B. Carneiro,
  • Ademilson Panunto-Castelo and
  • Maria Cristina Roque-Barreira
  • + 6 authors+ 1 author

10 October 2019

The microneme organelles of Toxoplasma gondii tachyzoites release protein complexes (MICs), including one composed of the transmembrane protein MIC6 plus MIC1 and MIC4. In this complex, carbohydrate recognition domains of MIC1 and MIC4 are exposed an...

(This article belongs to the Special Issue The Role of Glycosylation in Host-Microbial Interactions)
  • Article
  • Open Access
5 Citations
3,124 Views
13 Pages

Microneme Protein 6 Is Involved in Invasion and Egress by Neospora caninum

  • Xianmei Wang,
  • Di Tang,
  • Fei Wang,
  • Gaowei Jin and ,
  • Lifang Wang,
  • Qun Liu and
  • Jing Liu
  • + 2 authors+ 0 author

13 February 2021

Background: Neospora caninum, is the etiological agent of neosporosis, an infection that causes abortions in cattle and nervous system dysfunction in dogs. Invasion and egress are the key steps of the pathogenesis of N. caninum infection. Microneme p...

(This article belongs to the Special Issue Parasitic Diseases of Domestic, Wild, and Exotic Animals)
  • Article
  • Open Access
12 Citations
5,052 Views
12 Pages

Self-Reported Parental Interactions through Play with Young Children in Thailand: An Analysis of the 2019 Multiple Indicator Cluster Survey (MICS)

  • Thitikorn Topothai,
  • Rapeepong Suphanchaimat,
  • Chompoonut Topothai,
  • Viroj Tangcharoensathien and ,
  • Nisachol Cetthakrikul and
  • Orratai Waleewong
  • + 1 author+ 0 author

Parental interactions through play contributes significantly to child development of cognitive and executive functioning skills. In Thailand, there is little evidence of factors contributing to parental–child interactions. In response to SDG ta...

(This article belongs to the Special Issue The Role of Parenting in Typical and Atypical Child Development)
  • Article
  • Open Access
13 Citations
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12 Pages

Species Distribution of Candidemia and Their Susceptibility in a Single Japanese University Hospital: Prior Micafungin Use Affects the Appearance of Candida parapsilosis and Elevation of Micafungin MICs in Non-parapsilosis Candida Species

  • Yasutaka Sakamoto,
  • Kazuhiro Kawabe,
  • Tomoyo Suzuki,
  • Kayoko Sano and ,
  • Kazuo Ide,
  • Tetsuta Nishigaki,
  • Yuki Enoki,
  • Kazuaki Taguchi,
  • Hirofumi Koike and
  • Kazuaki Matsumoto
  • + 7 authors+ 2 authors

23 July 2021

Introduction: Micafungin is a recommended echinocandin antifungal agent for candidemia treatment and prophylaxis. However, overuse of echinocandin antifungals may cause resistance. There is currently no information available regarding the low suscept...

(This article belongs to the Section Fungal Pathogenesis and Disease Control)

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