Clinical Pharmacokinetics and Pharmacodynamics of Antimicrobial Therapy

Dear Colleagues,

We are pleased to invite you to contribute an original research article or review to this Special Issue of Pharmaceutics, entitled “Clinical Pharmacokinetics and Pharmacodynamics of Antimicrobial Therapy”.

Nowadays, an alarming rate of resistance against multiple currently available antimicrobial treatments is being observed. As misuse or abuse of this therapy is a key factor in the development of resistance, optimizing this therapy is pivotal to addressing this problem. The success of antimicrobial therapy depends on the pathogen, the therapy, and the patient. Given the variability in clinical practice, understanding the PK/PD of these treatments is crucial to achieving suitable concentrations for maximum efficacy and minimizing resistance development. Translational PK/PD, therapeutic drug monitoring (TDM), and model-informed precision dosing (MIPD) have emerged as key tools in guiding optimal dosing regimens. Furthermore, PK/PD analysis and modeling of antimicrobial therapy are important for informing dosage regimen selection, particularly in community medicine or critical situations where the pathogen or its susceptibility is unknown.

This Special Issue aims to provide readers with an understanding of how contemporary tools can guide the optimization of antimicrobial therapy. Research areas may include, but are not limited to, the following: special populations such as pediatrics, those who are critically ill, or the elderly, and treatments related to multidrug-resistant pathogens and clinical practice in humans or animals.

Dr. Hinojal Zazo
Dr. Amelia Ramon-Lopez
Dr. José Germán Sánchez-Hernández
Dr. Arantxa Isla
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 250 words) can be sent to the Editorial Office for assessment.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-anonymized peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Pharmaceutics is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2900 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.