Clinical Pharmacokinetics and Pharmacodynamics of Antimicrobial Therapy
A special issue of Pharmaceutics (ISSN 1999-4923). This special issue belongs to the section "Clinical Pharmaceutics".
Deadline for manuscript submissions: 31 May 2026 | Viewed by 92
Special Issue Editors
Interests: pharmacokinetics; PBPK model; PKPD modeling; drug monitoring; pharmacodynamics
Interests: pharmacokinetics; drug monitoring; model-informed precision dosing
Special Issues, Collections and Topics in MDPI journals
Interests: therapeutic drug monitoring; pharmacodynamics; pharmacokinetics
Interests: antibiotics; pharmacokinetics; pharmacodynamics; antimicrobials; MIPD
Special Issue Information
Dear Colleagues,
We are pleased to invite you to contribute an original research article or review to this Special Issue of Pharmaceutics, entitled “Clinical Pharmacokinetics and Pharmacodynamics of Antimicrobial Therapy”.
Nowadays, an alarming rate of resistance against multiple currently available antimicrobial treatments is being observed. As misuse or abuse of this therapy is a key factor in the development of resistance, optimizing this therapy is pivotal to addressing this problem. The success of antimicrobial therapy depends on the pathogen, the therapy, and the patient. Given the variability in clinical practice, understanding the PK/PD of these treatments is crucial to achieving suitable concentrations for maximum efficacy and minimizing resistance development. Translational PK/PD, therapeutic drug monitoring (TDM), and model-informed precision dosing (MIPD) have emerged as key tools in guiding optimal dosing regimens. Furthermore, PK/PD analysis and modeling of antimicrobial therapy are important for informing dosage regimen selection, particularly in community medicine or critical situations where the pathogen or its susceptibility is unknown.
This Special Issue aims to provide readers with an understanding of how contemporary tools can guide the optimization of antimicrobial therapy. Research areas may include, but are not limited to, the following: special populations such as pediatrics, those who are critically ill, or the elderly, and treatments related to multidrug-resistant pathogens and clinical practice in humans or animals.
Dr. Hinojal Zazo
Dr. Amelia Ramon-Lopez
Dr. José Germán Sánchez-Hernández
Dr. Arantxa Isla
Guest Editors
Manuscript Submission Information
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Keywords
- antimicrobial
- antibacterial
- antibiotics
- antifungal
- pharmacokinetics
- pharmacodynamics
- PK/PD
- MIPD
- drug monitoring
- TDM
- gentamicin
- vancomycin
- meropenem
- daptomycin
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