In this study, the methods and results of numerical simulations to estimate the motion performance of a newly developed lightweight light buoy in waves and to check the effect of conceptually developed appendages on that performance were introduced....
In the conventional FDEM (Combined Finite and Discrete Element Method), each contact pair might have multiple contact points where friction forces are applied, leading to non-unique friction force assignments and potentially introducing computational...
(1) Background: Gastroretentive systems are an interesting option for enhancing the bioavailability of weak bases and poorly soluble drugs. The aim of this study was to formulate supramolecular organogels based on cinnarizine (CIN) as a potential gas...
A new interatomic potential for the pure tin (Sn) system is developed on the basis of the second-nearest-neighbor modified embedded-atom-method formalism. The potential parameters were optimized based on the force-matching method utilizing the densit...
A new second nearest-neighbor modified embedded-atom model-based PtTi binary interatomic potential was developed by improving the pure Pt unary descriptions of the pre-existing interatomic potential. Specifically, the interatomic potential was develo...
Formation flight is one potential measure to increase the efficiency of aviation. Flying in the upwash region of an aircraft’s wake vortex field is aerodynamically advantageous. It saves fuel and concomitantly reduces the carbon foot print. How...
Background: Acute myeloid leukemia (AML) is a heterogeneous hematologic malignancy characterized by impaired differentiation, apoptosis resistance, and metabolic reprogramming, which collectively contribute to therapeutic resistance and poor clinical...
The formation of functionally versatile protein complexes underlies almost every biological process. The estimation of how fast these complexes can be formed has broad implications for unravelling the mechanism of biomolecular recognition. This kinet...
Here, we assess the projected changes in photovoltaic power generation potential (PVpot) in Greece for the 21st century. Our analysis is based on an ensemble of high-resolution Regional Climate Model (RCM) simulations from the EURO-CORDEX initiative...
Understanding fusion mechanisms employed by SARS-CoV-2 spike protein entails realistic transmembrane domain (TMD) models, while no reliable approaches towards predicting the 3D structure of transmembrane (TM) trimers exist. Here, we propose a compreh...
Antimicrobial resistance (AMR) is an emerging global health concern that demands the identification of novel drug targets and bioactive molecules to combat resistant bacterial pathogens. In the present study, AmvR, a TetR family transcriptional regul...
Background/Objectives: Eumycetoma, caused by Madurella mycetomatis, is a chronic fungal infection with limited treatment options and increasing drug resistance. CYP51, a key enzyme in ergosterol biosynthesis, is a well-established target for azole an...
Obesity is a pandemic and a serious health problem in developed and undeveloped countries. Activation of estrogen receptor beta (ERβ) has been shown to promote weight loss without modifying caloric intake, making it an attractive target for deve...
Crop production potential is an index used to evaluate crop productivity capacity in one region. The spatial production potential can help give the maximum value of crop yield and visually clarify the prospects of agricultural development. The DSSAT...
Since water shortage has been a serious challenge in Iran, long-term investigations of alternative water resources are vital. In this study, we performed long-term (1979–2018) model simulation at seven locations (costal, desert, mountain, and urban c...
Pre-alkalization caused by dietary supplements such as sodium bicarbonate improves anaerobic exercise performance. However, the influence of a base-forming nutrition on anaerobic performance in hypoxia remains unknown. Herein, we investigated the eff...
In this paper, we investigate our mobility-assisted and adaptive broadcast routing mechanism, called Mobility Tolerant Firework Routing (MTFR), which utilizes the concept of potentials for routing and improves node reachability, especially in situati...
Risk assessments (RAs) are frequently conducted to assess the potential effect of process parameters (PPs) on product quality attributes (e.g., a critical quality attribute (CQA)). To evaluate the PPs criticality the risk priority number (RPN) for ea...
Polyimide (PI) is widely used in aerospace applications due to its excellent properties. However, the high concentration of atomic oxygen (AO) in low-earth orbit (LEO) significantly degrades its performance. This study employs reactive molecular dyna...
A quantitative assessment of food-water-energy interactions is important to assess pathways and scenarios towards a holistically sustainable regional development. While a range of tools and methods exist that assess energetic demands and potentials o...
This paper investigates the formation tracking control of multiple agents with a double-integrator model and presents a novel distributed control framework composed of three items: a potential-based gradient term, a formation term, and a navigation t...
Research on the development of plants grown for energy purposes is important for ensuring the global energy supply and reducing greenhouse gas emissions, and simulation is an important method to study its potential. This paper evaluated the marginal...
Urban population potential is a good measure of urban spatial interactions. However, previous studies often assigned population data to the administrative point of the government or the centroid of the region, such as the county, ward or village. In...
Behaviour Demand Response (BDR) is an approach that enables the adaptation of operation of the district heating assets to dynamic market and capacity constraints by asking building occupants to participate and temporarily alter their demand profiles....
This study aimed to develop a physiologically based pharmacokinetic (PBPK) model of tegoprazan and to predict the drug–drug interaction (DDI) potential between tegoprazan and cytochrome P450 (CYP) 3A4 perpetrators. The PBPK model of tegoprazan was de...
The assessment of regional bioenergy potentials from different types of natural land cover is an integral part of simulation tools that aim to assess local renewable energy systems. This work introduces a new workflow, which evaluates regional bioene...
In this paper, a field–circuit combined simulation method, based on the magnetic scalar potential volume integral equation (MSP-VIE) and its fast algorithms, are proposed for the transient simulation and nonlinear distortion analysis of the mag...
This study investigates the degradation potential of metakaolin-based geopolymer (GP) composites when exposed to real and simulated acidic environments. Traditional OPC concrete, commonly used in wastewater treatment facilities, faces considerable de...
A new vertical axis-symmetrical dish-shaped autonomous underwater vehicle (AUV) with excellent maneuverability, known as the autonomous underwater hovering vehicle (AUH), is proposed. This study investigates an important working model of the AUH appr...
The crop model based on physiology and ecology has been widely applied to the simulation of regional potential productivity. By determining the appropriate spatial resolution of meteorological data required for model simulation for different regions,...
Potentilla nepalensis Hook is a perennial Himalayan medicinal herb of the Rosaceae family. The present study aimed to evaluate biological activities such as the antioxidant, antibacterial, and anticancer activities of roots and shoots of P. nepalensi...
Presently, there is increasing interest in autonomous ships to reduce human errors and support intelligent navigation, where automatic collision avoidance and path planning is a key problem, especially in restricted waters. To solve this problem, a p...
As an indispensable branch of machine learning (ML), reinforcement learning (RL) plays a prominent role in the decision-making process of autonomous driving (AD), which enables autonomous vehicles (AVs) to learn an optimal driving strategy through co...
This work addresses the effects of blade tip-rake reformation on the performance of marine propellers using a low-cost potential-based vortex-lattice method (VLM) and the high fidelity artificial compressibility CFD-RANS solver MaPFlow. The primary f...
Computer-based simulation (CBS) is an interactive pedagogical training method that has seen increased interest, especially in recent years. There is some evidence that CBS in pharmacy education is not as widely adopted compared to other healthcare di...
In this paper, we address the thermal rise and Quality-of-Service (QoS) provisioning issue for an intra-body Wireless Body Area Network (WBAN) having in-vivo sensor nodes. We propose a thermal-aware QoS routing protocol, called TLQoS, that facilitate...
To address the challenges posed by multiple uncertainties in modern power systems to the market bidding of Virtual Power Plants (VPPs), this paper proposes an adaptive bidding strategy based on Deep Reinforcement Learning (DRL). First, a heterogeneou...
Avian coccidiosis, caused by protozoan parasites of the genus Eimeria, poses a major threat to the poultry industry worldwide, leading to severe economic losses through reduced growth rates, poor feed efficiency, and increased mortality. Although the...
Rechargeable magnesium ion batteries have recently received considerable attention as an alternative to Li- or Na-ion batteries. Understanding defects and ion transport is a key step in designing high performance electrode materials for Mg-ion batter...
In this study, the nucleon density distributions of tungsten isotopes were calculated using the Skyrme interaction within Hartree–Fock approximation model based on the Woods–Saxon potential. Then, using these densities, the interaction po...
Toroidal propellers have emerged as a promising substitute for next-generation marine propulsors due to their potential advantages in hydrodynamic efficiency and noise control. This article presents a hydrodynamic analysis of toroidal propellers usin...
Due to their excellent specific strength and lightweight characteristics, Al-Cu-Li alloys are widely used in aerospace applications. The newly developed three-stage creep aging (CA) process ensures both the formability and high performance of the Al...
Placing porous media in a water tank can change the dynamic characteristics of the sloshing fluid. Its extra damping effect can mitigate sloshing and, thereby, protect the integrity of a liquefied natural gas tank. In addition, the out-of-phase slosh...
The integration of renewable energy sources (RES) into energy systems is becoming increasingly widespread around the world, driven by various factors, the most relevant of which is the high environmental friendliness of these types of energy resource...
Thermally activated building systems (TABS) rely on high thermal mass materials, such as concrete, which perform well thermally but have a high carbon footprint. This study systematically investigates the thermal behavior of bio-based materials&mdash...
Large Unmanned Underwater Vehicles (UUVs) are playing an increasingly critical role in complex marine missions due to their enhanced payload and endurance capabilities. However, the safe recovery of these platforms remains a significant challenge, co...
This is a comprehensive research endeavor focused on enhancing the efficiency of the proposed solar cell design. The integration of the simulation techniques, judicious material selection, and meticulous performance metrics showcase a methodical appr...
Soil salinity and water deficit are important challenges for sustainable agricultural development in arid and semi-arid regions. While soil salinity and water deficits may result in lower crop yields, they may improve crop quality. The quantitative r...
Globally, breast cancer (BC), the second-biggest cause of cancer death, occurs due to unregulated cell proliferation leading to metastasis to other parts of the human organ. Recently, the exploration of naturally derived anticancer agents has become...
With the development of unmanned combat air vehicles (UCAVs) and artificial intelligence (AI), within visual range (WVR) air combat confrontations utilizing intelligent UCAVs are expected to be widely used in future air combats. As controlling highly...
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