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71 Results Found

  • Communication
  • Open Access
15 Citations
4,068 Views
7 Pages

9 August 2021

RNA therapies using RNA editing and interference are currently being developed for neurological diseases. The CRISPR-Cas13 system, based on bacterial enzymes, holds great promise for developing efficient tools for RNA therapies. However, neurotoxic a...

(This article belongs to the Section Molecular and Cellular Neuroscience)
  • Article
  • Open Access
117 Citations
18,647 Views
19 Pages

Value–belief–norm (VBN) theory provides a valuable framework for identifying the social-psychological determinants of various types of pro-environmental behavior. However, limited empirical study has tested the applicability of VBN theory...

(This article belongs to the Section Sustainable Education and Approaches)
  • Commentary
  • Open Access
9 Citations
4,717 Views
8 Pages

Practical Aspects of Twin Pregnancy Diagnosis in Cattle

  • Zoltán Szelényi,
  • Ottó Szenci,
  • Levente Kovács and
  • Irina Garcia-Ispierto

8 April 2021

Twin pregnancies are an economically unwanted phenomenon in dairy cattle, not only because they increase pregnancy losses, but also because antibiotics usage and culling rate of the dam are also dramatically increased due to them, furthermore animal...

(This article belongs to the Special Issue Therapeutics of Twin Pregnancies in Dairy Cattle)
  • Article
  • Open Access
1 Citations
1,559 Views
23 Pages

Bacterial lux-Biosensors for Detecting Specific Cell Responses to Membrane Damage

  • Vladimir A. Plyuta,
  • Evgeny Y. Gnuchikh,
  • Anastasiia A. Gorbunova,
  • Veronika D. Udovichenko and ,
  • Kristina A. Sinyakova,
  • Daria E. Sidorova,
  • Olga A. Koksharova,
  • Sergey V. Bazhenov and
  • Olga E. Melkina
  • + 4 authors+ 0 author

26 November 2025

Whole-cell biosensors represent one of the tools used for assessing the effects of various agents on living cells. Here we have constructed and tested whole-cell lux-biosensors to detect membrane damage in both Gram-negative and Gram-positive bacteri...

(This article belongs to the Special Issue Microbial Biosensor: From Design to Applications—2nd Edition)
  • Article
  • Open Access
6 Citations
5,556 Views
17 Pages

Lp16-PSP, a Member of YjgF/YER057c/UK114 Protein Family Induces Apoptosis and p21WAF1/CIP1 Mediated G1 Cell Cycle Arrest in Human Acute Promyelocytic Leukemia (APL) HL-60 Cells

  • Thomson Patrick Joseph,
  • Warren Chanda,
  • Abdullah Faqeer Mohammad,
  • Sadia Kanwal and ,
  • Samana Batool,
  • Meishan Zhang,
  • Mintao Zhong and
  • Min Huang
  • + 3 authors+ 0 author

13 November 2017

Lp16-PSP (Latcripin 16-Perchloric acid Soluble Protein) from Lentinula edodes strain C91-3 has been reported previously in our laboratory to have selective cytotoxic activity against a panel of human cell lines. Herein, we have used several parameter...

(This article belongs to the Section Biochemistry)
  • Review
  • Open Access
52 Citations
14,464 Views
18 Pages

3 June 2021

One of the most recent techniques for the on-farm diagnosis of early pregnancy (EP) in cattle is B-mode ultrasonography. Under field conditions, acceptable results may be achieved with ultrasonography from Days 25 to 30 post-AI. The reliability of th...

(This article belongs to the Collection High-Yielding Dairy Cows)
  • Article
  • Open Access
15 Citations
3,571 Views
15 Pages

Effect of Oxygen Mole Fraction on Static Properties of Pressure-Sensitive Paint

  • Tomohiro Okudera,
  • Takayuki Nagata,
  • Miku Kasai,
  • Yuji Saito and ,
  • Taku Nonomura and
  • Keisuke Asai
  • + 1 author+ 0 author

4 February 2021

The effects of the oxygen mole fraction on the static properties of pressure-sensitive paint (PSP) were investigated. Sample coupon tests using a calibration chamber were conducted for poly(hexafluoroisopropyl methacrylate)-based PSP (PHFIPM-PSP), po...

(This article belongs to the Special Issue Optical Sensors for Flow Diagnostics)
  • Article
  • Open Access
28 Citations
3,884 Views
14 Pages

Pumpkin Skin Polysaccharide–Zn(II) Complex: Preparation, Characterization, and Suppression of Inflammation in Zebrafish

  • Shujun Dong,
  • Bin Zhang,
  • Yue Ma,
  • Hong Chang and ,
  • Zhenjia Zheng and
  • Xiaoyan Zhao
  • + 1 author+ 0 author

28 August 2022

In this study, pumpkin (Cucurbita moschata) skin polysaccharide–zinc(II) (PSP−Zn) complex was successfully prepared. The structure and physicochemical properties of PSP and PSP−Zn were analyzed. The anti-inflammatory activity of PSP...

(This article belongs to the Section Food Physics and (Bio)Chemistry)
  • Article
  • Open Access
10 Citations
6,128 Views
25 Pages

Progressive Sample Processing of Band Selection for Hyperspectral Image Transmission

  • Keng-Hao Liu,
  • Shih-Yu Chen,
  • Hung-Chang Chien and
  • Meng-Han Lu

26 February 2018

Band selection (BS) is one of the important topics in hyperspectral image (HSI) processing. Many types of BS algorithms were proposed in the last decade. However, most of them were designed for off-line use. They can only be used with pre-collected d...

(This article belongs to the Special Issue Hyperspectral Imaging and Applications)
  • Article
  • Open Access
41 Citations
3,746 Views
12 Pages

28 February 2024

In this study, three homogeneous fractions, PSP-N-b-1, PSP-N-b-2, and PSP-N-c-1, were obtained from an aqueous extract of Polygonatum using DEAE cellulose column chromatography, CL-6B agarose gel chromatography, and Sephadex G100 chromatography. Thei...

(This article belongs to the Special Issue Chitosan, Chitosan Derivatives, Polysaccharides and Their Applications—2nd Edition)
  • Article
  • Open Access
2 Citations
1,244 Views
27 Pages

Structural Characterization and Anti-Colitis Mechanisms of Polygonatum sibiricum Polysaccharides via Modulation of Neutrophil Extracellular Traps (NETs)—Macrophage Crosstalk

  • Jiaman Xu,
  • Junna Zheng,
  • Wukang Ke,
  • Yu Qiu and ,
  • Lu Zhang,
  • Chenxi Wu,
  • Xiaoxi Zhang,
  • Daozong Xia and
  • Fenfen Li
  • + 4 authors+ 0 author

25 March 2026

Background: Polygonatum sibiricum (PS), a perennial herbaceous plant belonging to the Liliaceae family, is widely distributed in China and other East Asian countries. PS has been used as food and medicine for thousands of years, and its rhizomes are...

(This article belongs to the Section Phytochemicals and Human Health)
  • Article
  • Open Access
511 Views
19 Pages

25 June 2026

Background/Objectives: Ultrasound-guided fascial plane blocks have emerged as opioid-sparing analgesic strategies for cardiac surgery; however, evidence regarding combined block techniques remains limited. This randomized controlled trial evaluated t...

(This article belongs to the Special Issue New Insights into Regional Anesthesia and Pain Management)
  • Article
  • Open Access
68 Citations
5,910 Views
18 Pages

Immunostimulatory Effects of Polysaccharides from Spirulina platensis In Vivo and Vitro and Their Activation Mechanism on RAW246.7 Macrophages

  • Xueyan Wu,
  • Zhicong Liu,
  • Yang Liu,
  • Yu Yang and ,
  • Fulin Shi,
  • Kit-Leong Cheong and
  • Bo Teng
  • + 2 authors+ 0 author

28 October 2020

In this study, Spirulina platensis (S.p.) polysaccharide (PSP) was obtained by ultrasonic-microwave-assisted extraction (UMAE) and purified by an aqueous two-phase system (ATPS). Two different methods were applied to purified Spirulina platensis (S.p...

  • Article
  • Open Access
3 Citations
3,673 Views
16 Pages

Public safety personnel (PSP) experience an elevated risk of mental health problems and face barriers to treatment. Internet-delivered cognitive behavioral therapy (ICBT) has been tailored to PSP to improve access to mental health care. In this study...

(This article belongs to the Section Mental Health)
  • Article
  • Open Access
4 Citations
2,544 Views
11 Pages

Microstructural Evolution and Mechanical Properties of a Ni-Based Alloy with High Boron Content for the Pre-Sintered Preform (PSP) Application

  • Xiufang Gong,
  • Yunsheng Wu,
  • Zhenhuan Gao,
  • Youbei Sun and ,
  • Yingbo Guan,
  • Xianjun Guan,
  • Xuezhi Qin,
  • Jieshan Hou and
  • Lanzhang Zhou
  • + 4 authors+ 0 author

2 December 2023

The pre-sintered preform (PSP) is an advanced technology for repairing the Ni-based superalloy blade in a turbine. In general, boron is added to the Ni-based superalloys in small quantities (<0.1 wt.%) to increase boundary strength and cohesivity....

(This article belongs to the Section Smart and Functional Materials)
  • Article
  • Open Access
2 Citations
2,320 Views
18 Pages

5 July 2025

Background: Obesity-associated metabolic disorders represent a critical global health challenge, which necessitates innovative strategies targeting lipid metabolism. Peanut skin procyanidins (PSPs), abundant bioactive compounds derived from agricultu...

(This article belongs to the Section Nutrition and Metabolism)
  • Article
  • Open Access
11 Citations
3,407 Views
13 Pages

Plasma microRNAs as a Potential Biomarker for Identification of Progressive Supranuclear Palsy

  • Palaniswamy Ramaswamy,
  • Rita Christopher,
  • Pramod Kumar Pal,
  • Monojit Debnath and
  • Ravi Yadav

Progressive supranuclear palsy (PSP) is the second most common Parkinsonian disorder with complex etiology. The underlying molecular mechanism of PSP pathogenesis remains unclear. The present study aims to find the feasibility of using plasma miRNAs...

(This article belongs to the Section Pathology and Molecular Diagnostics)
  • Article
  • Open Access
32 Citations
5,781 Views
21 Pages

28 May 2020

The aim of the present paper is to investigate the use of the site “Potamon” Dam in the Prefecture of Rethymnon, Crete island, Greece, as a “virtual” renewable electricity supply of a pumped storage plant (PSP) in order to sav...

(This article belongs to the Section A3: Wind, Wave and Tidal Energy)
  • Article
  • Open Access
9 Citations
3,290 Views
16 Pages

Investigating the Antidepressant Mechanisms of Polygonum sibiricum Polysaccharides via Microglial Polarization

  • Yingyu Zhang,
  • Danyang Wang,
  • Jiameng Liu,
  • Jing Sun and ,
  • Xinmin Liu,
  • Bei Fan,
  • Cong Lu and
  • Fengzhong Wang
  • + 3 authors+ 0 author

1 February 2024

Polygonum sibiricum, with its medicinal and edibility dual properties, has been widely recognized and utilized throughout Chinese history. As a kind of its effective component, Polygonum sibiricum polysaccharides (PSP) have been reported to be a prom...

(This article belongs to the Section Carbohydrates)
  • Article
  • Open Access
7 Citations
3,752 Views
19 Pages

The influence of carbon nanotube (CNT) modification on the dispersion and localization behavior of the CNTs in immiscible blends of polystyrene (PS) and polybutadiene (PB), and in the nanostructured morphology of a star-shaped styrene-butadiene based...

(This article belongs to the Special Issue Recent Advances in Conductive Polymer Composites)
  • Article
  • Open Access
2 Citations
1,198 Views
21 Pages

8 February 2026

Objective: The formation of calcium oxalate (CaOx) kidney stones is accompanied by the pyroptosis of renal epithelial cells. The risk of kidney stone formation can possibly be reduced through pyroptosis inhibition. Methods: Pyroptosis of HK-2 cells i...

(This article belongs to the Section Marine Pharmacology)
  • Communication
  • Open Access
4 Citations
3,641 Views
11 Pages

7 December 2020

The flexible photonics spectral processor (PSP) is an indispensable element for elastic optical transmission networks that adopt wavelength division multiplexing (WDM) technology. The resolution and system cost are two vital metrics when developing a...

(This article belongs to the Special Issue Photonics for Emerging Applications in Communication and Sensing)
  • Article
  • Open Access
14 Citations
6,900 Views
11 Pages

Simulation of Binodal and Spinodal Curves of Phase State Diagrams for Binary Polymer Systems

  • Anatoly E. Chalykh,
  • Uliana V. Nikulova and
  • Vladimir K. Gerasimov

21 June 2022

A new approach is proposed for simulating binodal and spinodal curves of phase diagrams for binary polymer systems. It is shown that the Flory–Huggins theory makes it possible to predict phase behavior in a wide range of temperatures and concen...

(This article belongs to the Section Innovation of Polymer Science and Technology)
  • Article
  • Open Access
9 Citations
2,939 Views
13 Pages

Efficacy of a Protein Vaccine and a Conjugate Vaccine Against Co-Colonization with Vaccine-Type and Non-Vaccine Type Pneumococci in Mice

  • Gabriela B. C. Colichio,
  • Giuliana S. Oliveira,
  • Tasson C. Rodrigues,
  • Maria Leonor S. Oliveira and
  • Eliane N. Miyaji

Widespread use of pneumococcal conjugate vaccines (PCVs) has led to substitution of vaccine-type (VT) strains by non-vaccine type (NVT) strains in nasopharyngeal carriage. We compared the efficacy of PCV13 and a nasal protein formulation containing p...

(This article belongs to the Section Vaccines and Therapeutic Developments)
  • Article
  • Open Access
1 Citations
3,041 Views
15 Pages

Robust Immune Response and Protection against Lethal Pneumococcal Challenge with a Recombinant BCG-PspA-PdT Prime/Boost Scheme Administered to Neonatal Mice

  • Monalisa Martins Trentini,
  • Dunia Rodriguez,
  • Alex Issamu Kanno,
  • Cibelly Goulart and ,
  • Michelle Darrieux and
  • Luciana Cezar de Cerqueira Leite
  • + 1 author+ 0 author

25 January 2024

Pneumococcal diseases are an important public health problem, with high mortality rates in young children. Although conjugated pneumococcal vaccines offer high protection against invasive pneumococcal diseases, this is restricted to vaccine serotypes...

(This article belongs to the Special Issue Research on Immune Response and Vaccines)
  • Article
  • Open Access
25 Citations
7,854 Views
12 Pages

Assessing the Perceptions and Impact of Critical Incident Stress Management Peer Support among Firefighters and Paramedics in Canada

  • Jill A. B. Price,
  • Caeleigh A. Landry,
  • Jeff Sych,
  • Malcolm McNeill and ,
  • Andrea M. Stelnicki,
  • Aleiia J. N. Asmundson and
  • R. Nicholas Carleton
  • + 2 authors+ 0 author

Relative to the general population, public safety personnel (PSP) appear at an increased risk of developing mental health challenges as a result of repeated exposure to potentially psychologically traumatic events (PPTEs). To help mitigate the impact...

(This article belongs to the Special Issue Health and Wellness in the Workplace)
  • Article
  • Open Access
15 Citations
10,860 Views
17 Pages

Nutritional, Biochemical, and Functional Properties of Spinach Leaf-Enriched Dough: A Healthier Alternative to Conventional Pasta

  • Ilaria Iacobellis,
  • Alessia Lisi,
  • Mirco Vacca,
  • Carmen Aurora Apa and ,
  • Giuseppe Celano,
  • Leonardo Mancini,
  • Fabio Minervini,
  • Maria Calasso and
  • Maria De Angelis
  • + 4 authors+ 0 author

12 November 2024

This study explored the effects of spinach flour (SF) enrichment on pasta, focusing on chemical, nutritional and sensory properties, cooking performance, and microbiological stability. SF was added at 12.5% (PSP12) and 25% (PSP25). The enriched pasta...

(This article belongs to the Special Issue Advances in Improvement and Fortification of Cereal Food)
  • Article
  • Open Access
1,075 Views
22 Pages

Time- and Dose-Dependent PSP-Induced Modulation of Antiviral Signaling Networks in CD4+ T Cells

  • Glamaris N. Rosario-Sanfiorenzo,
  • Giovanni O. Alicea-Pérez,
  • Ashlin N. Álvarez-Flores,
  • Naiara I. Hernández-Santisteban and ,
  • Amanda C. Rivera-Payán,
  • Jeshua J. Colón-Fernández,
  • Abigail M. Rivera-Berganzo,
  • Victoria Bermudez-Fosse,
  • Ileanmarie Santana-Costas and
  • Eduardo Álvarez-Rivera
  • + 11 authors+ 6 authors

Natural bioactive polysaccharides have been investigated for their ability to modulate antiviral immune responses. Polysaccharide peptide (PSP) from Coriolus versicolor previously restricted human immunodeficiency virus type 1 (HIV-1) entry into mono...

(This article belongs to the Special Issue HIV Expression in Diverse Cell Types: Mechanisms, Regulation, and Pathogenesis)
  • Review
  • Open Access
6 Citations
4,234 Views
36 Pages

A Review of FDG-PET in Progressive Supranuclear Palsy and Corticobasal Syndrome

  • Alexandros Giannakis,
  • Eugenia Kloufetou,
  • Louisa Pechlivani,
  • Chrissa Sioka and ,
  • George Alexiou,
  • Spiridon Konitsiotis and
  • Athanassios P. Kyritsis
  • + 2 authors+ 0 author

26 August 2025

Although diagnostic criteria and research are constantly advancing, distinguishing between progressive supranuclear palsy (PSP) and corticobasal syndrome (CBS) remains a significant challenge. This difficulty stems from their similar clinical symptom...

(This article belongs to the Section Molecular Neurobiology)
  • Article
  • Open Access
8 Citations
2,872 Views
18 Pages

Polygonatum sibiricum Polysaccharides Alleviate Simulated Weightlessness-Induced Cognitive Impairment by Gut Microbiota Modulation and Suppression of NLRP3/NF-κB Pathways

  • Fang Chen,
  • Muhammad Noman Khan,
  • Mengzhou Xie,
  • Yiwen Zhang and ,
  • Liang Li,
  • Ahsana Dar Farooq,
  • Jixian Liu,
  • Qinghu He,
  • Xinmin Liu and
  • Ning Jiang
  • + 5 authors+ 0 author

5 October 2025

Background/Objectives: Polygonatum sibiricum (PS), possessing both medicinal and edible dual functions, boasts a long history of application in Chinese traditional practices. As a component of its effectiveness, Polygonatum sibiricum polysaccharides...

(This article belongs to the Section Carbohydrates)
  • Article
  • Open Access
2 Citations
2,757 Views
17 Pages

Pressure Sensitivity Prediction and Pressure Measurement of Fast Response Pressure-Sensitive Paint Based on Artificial Neural Network

  • Xianhui Liao,
  • Chunhua Wei,
  • Chenglin Zuo,
  • Zhisheng Gao and ,
  • Hailin Jiang,
  • Lei Liang and
  • Zhaoyan Li
  • + 2 authors+ 0 author

9 March 2023

The characterization of pressure-sensitive paint (PSP) is affected by many physical and chemical factors, making it is difficult to analyze the relationship between characterization and influencing factors. An artificial neural network (ANN)-based me...

(This article belongs to the Special Issue Applications of Deep Learning and Artificial Intelligence Methods)
  • Article
  • Open Access
912 Views
25 Pages

Protective Effects of Polysaccharides from Pyropia suborbiculata Against UVB-Induced Photodamage in HaCaT Cells

  • Kaiyue Chen,
  • Hongchang Ding,
  • Jiawei Zhong,
  • Qinwen Zhou and ,
  • Yujia Li,
  • Long Zhang,
  • Quancai Sun,
  • Ye Peng,
  • Wenhui Wu and
  • Wanqiang Wu
  • + 6 authors+ 1 author

9 April 2026

Porphyra suborbiculata exhibits strong heat tolerance and has considerable commercial potential under rising sea temperatures; however, its bioactive components remain insufficiently explored. In this study, a heat-tolerant new strain of P. suborbicu...

(This article belongs to the Section Nutraceuticals, Functional Foods, and Novel Foods)
  • Review
  • Open Access
69 Views
35 Pages

Anti-Aging Effects of Polygonatum spp. Polysaccharides: Pharmacological Evidence, Molecular Mechanisms, and Structure–Activity Relationships

  • Jianhong Xie,
  • Jing Wang,
  • Juan Xu,
  • Lei Cheng and ,
  • Yifan Zeng,
  • Qingjun Shu,
  • Yaping Wang and
  • Baozhong Duan
  • + 3 authors+ 0 author

5 November 2026

Polygonatum species are medicinal and edible plants whose polysaccharides (PSPs) have attracted interest for their potential anti-aging effects. This review synthesizes evidence on the structural characteristics, pharmacological activities, molecular...

(This article belongs to the Special Issue Botanical Compounds and Their Medicinal Applications)
  • Article
  • Open Access
13 Citations
3,953 Views
22 Pages

First Crystal Structure of Bacterial Oligopeptidase B in an Intermediate State: The Roles of the Hinge Region Modification and Spermine

  • Dmitry E. Petrenko,
  • Vladimir I. Timofeev,
  • Vladimir V. Britikov,
  • Elena V. Britikova and ,
  • Sergey Y. Kleymenov,
  • Anna V. Vlaskina,
  • Inna P. Kuranova,
  • Anna G. Mikhailova and
  • Tatiana V. Rakitina
  • + 4 authors+ 0 author

9 October 2021

Oligopeptidase B (OpB) is a two-domain, trypsin-like serine peptidase belonging to the S9 prolyloligopeptidase (POP) family. Two domains are linked by a hinge region that participates in the transition of the enzyme between two major states—closed an...

  • Feature Paper
  • Article
  • Open Access
8 Citations
3,902 Views
26 Pages

Identification of Sensitive Parameters for Deformation of Asphalt Concrete Face Rockfill Dam of Pumped Storage Power Station

  • Baotai Ma,
  • Wenbing Zhang,
  • Zhenzhong Shen,
  • Donghao Zhou and ,
  • Haozheng Yao and
  • Runye Wang
  • + 1 author+ 0 author

26 August 2022

Pumped storage power station (PSPS) is an important clean energy project that plays an important role in ensuring the economical, safe, and stable operation of power systems and alleviating the contradiction of peak load regulation. Deformation analy...

(This article belongs to the Special Issue Safety Monitoring and Management of Reservoir and Dams)
  • Article
  • Open Access
29 Citations
9,471 Views
20 Pages

24 September 2020

Various studies indicate that vaccination, especially with pneumococcal vaccines, protects against symptomatic cases of SARS-CoV-2 infection and death. This paper explores the possibility that pneumococcal vaccines in particular, but perhaps other va...

(This article belongs to the Special Issue Unraveling SARS-CoV-2 Pathogenesis: Development of Vaccines and Therapeutics for COVID-19)
  • Article
  • Open Access
29 Citations
4,168 Views
12 Pages

Research on the Impact of Deep Eutectic Solvent and Hot-Water Extraction Methods on the Structure of Polygonatum sibiricum Polysaccharides

  • Chunyan Zhang,
  • Lanfang Tang,
  • Xiaojun Su,
  • Qingming Li and ,
  • Hongying Guo,
  • Zhiwei Liu,
  • Zhongshan Wei and
  • Feng Wang
  • + 3 authors+ 0 author

8 October 2023

Deep eutectic solvent (DES) and hot-water extraction (HWE) methods were utilized to extract polysaccharides from Polygonatum sibiricum, referred to as DPsP and WPsP, respectively. The extracted polysaccharides were purified using the Superdex-200 dex...

(This article belongs to the Special Issue Research and Application of Plant Sourced Polysaccharides)
  • Article
  • Open Access
4 Citations
2,108 Views
20 Pages

11 October 2024

The linear diblock copolymer polystyrene-b-poly(4-vinylpyridine) (PS-P4VP) is an important copolymer recently used in many applications such as optoelectronics, sensors, catalysis, membranes, energy conversion, energy storage devices, photolithograph...

(This article belongs to the Section Materials Chemistry)
  • Article
  • Open Access
12 Citations
3,842 Views
9 Pages

Impact of Left Ventricular Diastolic Dysfunction and Biomarkers on Pulmonary Hypertension in Patients with Severe Aortic Stenosis

  • Birutė Gumauskienė,
  • Aušra Krivickienė,
  • Regina Jonkaitienė,
  • Jolanta Justina Vaškelytė and ,
  • Adakrius Siudikas and
  • Eglė Ereminienė
  • + 1 author+ 0 author

4 September 2018

Background: Severe aortic stenosis (AS) complicated by pulmonary hypertension (PH) is associated with poor outcomes after surgical aortic valve replacement (AVR). There is still scarce information about predictors of secondary PH in this group of pat...

  • Article
  • Open Access
11 Citations
4,188 Views
15 Pages

Prevalence of Various Vaccine Candidate Proteins in Clinical Isolates of Streptococcus pneumoniae: Characterization of the Novel Pht Fusion Proteins PhtA/B and PhtA/D

  • Mitsuyo Kawaguchiya,
  • Noriko Urushibara,
  • Meiji Soe Aung,
  • Masaaki Shinagawa and ,
  • Satoshi Takahashi and
  • Nobumichi Kobayashi
  • + 1 author+ 0 author

24 September 2019

Pneumococcal proteins unrelated to serotypes are considered to be candidates of antigens in next-generation vaccines. In the present study, the prevalence of vaccine candidate protein genes, along with serotypes and antimicrobial resistance determina...

(This article belongs to the Section Human Pathogens)
  • Article
  • Open Access
24 Citations
6,779 Views
17 Pages

Amphiphilic Block Copolymer Micelles in Selective Solvents: The Effect of Solvent Selectivity on Micelle Formation

  • Labeesh Kumar,
  • Andriy Horechyy,
  • Eva Bittrich,
  • Bhanu Nandan and ,
  • Petra Uhlmann and
  • Andreas Fery
  • + 1 author+ 0 author

14 November 2019

We investigated the micellar behavior of a series of asymmetric polystyrene-block-poly(4-vinylpyridine) (PS-b-P4VP) block copolymers in different P4VP-selective alcoholic solvents. The micellar behavior was further correlated with the spectroscopic e...

(This article belongs to the Special Issue Self-assembly of Block Copolymers)
  • Article
  • Open Access
10 Citations
8,121 Views
15 Pages

27 September 2019

When a planing boat sails at the free surface, the posture changes drastically with time, so the surface piercing propellers usually work in oblique flow. In this paper, numerical simulations are performed to predict the performance of PSP-841B with...

(This article belongs to the Section Hydraulics and Hydrodynamics)
  • Article
  • Open Access
44 Citations
5,413 Views
16 Pages

20 April 2021

The accumulation of proline is one of the defense mechanisms of plants against the harmful effects of adverse environmental conditions; however, when pea plants were treated for 12 h with CdCl2, the proline concentration decreased in the youngest A (...

(This article belongs to the Section Plant, Algae and Fungi Cell Biology)
  • Systematic Review
  • Open Access
17 Citations
4,072 Views
13 Pages

26 March 2022

Background and Objectives: Multiple system atrophy (MSA) and progressive supranuclear palsy (PSP) are rare atypical parkinsonian syndromes, characterized by motor and cognitive symptoms. Their clinical diagnosis is challenging because there are no es...

(This article belongs to the Special Issue Biomarkers in Alzheimer Disease and Other Dementias: What’s Next into Pathophysiology to Support Clinical Practice and Drug Development)
  • Article
  • Open Access
25 Citations
5,659 Views
20 Pages

Chemically Synthesized Alcaligenes Lipid A Shows a Potent and Safe Nasal Vaccine Adjuvant Activity for the Induction of Streptococcus pneumoniae-Specific IgA and Th17 Mediated Protective Immunity

  • Ken Yoshii,
  • Koji Hosomi,
  • Atsushi Shimoyama,
  • Yunru Wang and ,
  • Haruki Yamaura,
  • Takahiro Nagatake,
  • Hidehiko Suzuki,
  • Huangwenxian Lan,
  • Hiroshi Kiyono and
  • Jun Kunisawa
  • + 6 authors+ 1 author

Effective and safe vaccine adjuvants are needed to appropriately augment mucosal vaccine effects. Our previous study demonstrated that lipopolysaccharide (LPS) from Peyer’s patch resident Alcaligenes stimulated dendritic cells to promote the pr...

(This article belongs to the Special Issue Innate Immunity against Bacterial Infections)
  • Article
  • Open Access
6 Citations
1,754 Views
23 Pages

15 August 2025

In Thailand, companies are facing increasing pressure from investors, consumers, customers, and regulators to integrate sustainability into business policies and practices. Achieving corporate sustainable development requires incorporating environmen...

(This article belongs to the Section Economic and Business Aspects of Sustainability)
  • Article
  • Open Access
6 Citations
3,231 Views
17 Pages

Supplementation of Schisandrin B in Semen Extender Improves Quality and Oxidation Resistance of Boar Spermatozoa Stored at 4 °C

  • Yunfa Xie,
  • Zhiying Chen,
  • Yanling Wang,
  • Xiayun Peng and ,
  • Ni Feng,
  • Xiaoye Wang,
  • Yinsheng Tang,
  • Xun Li,
  • Chunrong Xu and
  • Chuanhuo Hu
  • + 5 authors+ 0 author

25 February 2023

During cold storage, boar spermatozoa undergo oxidative stress, which can impair sperm function and fertilizing capacity. The objective of the present study was to assess the effects of Schisandrin B (Sch B) in semen extenders on the quality of boar...

(This article belongs to the Special Issue Cryopreservation Technologies in Farm Animal Reproduction: Current Status and Future Perspectives)
  • Article
  • Open Access
17 Citations
8,422 Views
16 Pages

Paralytic Toxins Accumulation and Tissue Expression of α-Amylase and Lipase Genes in the Pacific Oyster Crassostrea gigas Fed with the Neurotoxic Dinoflagellate Alexandrium catenella

  • Jean-Luc Rolland,
  • Kevin Pelletier,
  • Estelle Masseret,
  • Fabien Rieuvilleneuve and ,
  • Veronique Savar,
  • Adrien Santini,
  • Zouher Amzil and
  • Mohamed Laabir
  • + 3 authors+ 0 author

12 November 2012

The pacific oyster Crassostrea gigas was experimentally exposed to the neurotoxic Alexandrium catenella and a non-producer of PSTs, Alexandrium tamarense (control algae), at concentrations corresponding to those observed during the blooming period. A...

(This article belongs to the Special Issue Marine Neurotoxins)
  • Article
  • Open Access
11 Citations
6,781 Views
17 Pages

15 April 2015

The separation of PSP toxins using liquid chromatography with a post-column oxidation fluorescence detection method was performed with different matrices. The separation of PSP toxins depends on several factors, and it is crucial to take into account...

(This article belongs to the Collection Marine and Freshwater Toxins)
  • Article
  • Open Access
1 Citations
3,551 Views
18 Pages

Analysis of Genetic and MRI Changes, Blood Markers, and Risk Factors in a Twin Pair Discordant of Progressive Supranuclear Palsy

  • Aliz Persely,
  • Beatrix Beszedics,
  • Krisztina Paloczi,
  • Marton Piroska and ,
  • Amirreza Alijanpourotaghsara,
  • David Strelnikov,
  • Arsalan Vessal,
  • Helga Szabo,
  • Anita Hernyes and
  • David Laszlo Tarnoki
  • + 13 authors+ 8 authors

22 September 2023

Background and Objectives: Progressive supranuclear palsy (PSP) is a neurodegenerative disease, a tauopathy, which results in a wide clinical spectrum of neurological symptoms. The diagnosis is mostly based on clinical signs and neuroimaging; however...

(This article belongs to the Special Issue Twin Studies and Imaging)

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