Background. The 5-year overall survival (OS) rates of T-cell lymphocytic leukemia (T-ALL) are better for children (>90%) compared to adults (~57%). The early T-cell precursor (ETP) T-ALL subtype is prognostically unfavorable in adults, but less si...
In the present study, room temperature (RTR) and cryogenic (CR) rolling of electrolytic tough pitch copper (ETP-Cu) was performed to elucidate how deformation temperature and reduction ratio (40% and 80% thickness reductions) control dislocation stor...
The evolution of microstructure and mechanical properties in electrolytic tough-pitch (ETP) copper subjected to hybrid friction welding (HFW) was investigated. The effect of introducing a programmable brake on the flywheel’s rotation while main...
Spot Bitcoin Exchange Traded Products (ETPs) are financial instruments enabling Bitcoin to be traded on traditional brokerage platforms, reducing the risks associated with direct Bitcoin exposure while addressing fraud and market manipulation concern...
The wire drawing process is commonly perceived as one of the best studied metal forming processes in almost every aspect; however, when considering elastic deformation, researchers usually focus on the uniaxial tensile forces after the material exits...
Today’s world is a place where lack of electrical energy would be unimaginable for most of society. All the conductors in the world, both aluminum and copper, have their origin in various types of casting lines where the liquid metal after crystalliz...
T-cell acute lymphoblastic leukemia (T-ALL) is an aggressive subtype of ALL characterized by unfavorable clinical outcomes. Despite significant progress in deciphering the genetic and epigenetic landscapes of T-ALL, the underlying molecular mechanism...
Due to their exceptional electrical and thermal conductivity properties, high-purity copper (Cu-DHP) and copper alloys of similar composition, such as electrolytic tough-pitch (ETP), oxygen-free electronic (OFE) and oxygen-free (OF), have often been...
Early T-cell precursor (ETP) is an aggressive form of acute lymphoblastic leukemia (ALL), associated with high risk of relapse. This leukemia subtype shows a higher prevalence of mutations, typically associated with acute myeloid leukemia (AML), incl...
T-cell acute lymphoblastic leukemia (T-ALL) accounts for 15% of childhood ALL. The early T-precursor (ETP-ALL) subset is characterized by an immature T-cell phenotype, chemoresistance, and high rates of induction failure. MERTK receptor tyrosine kina...
Early T-cell precursor acute lymphoblastic leukemia (ETP-ALL) develops from very early cells with the potential for both T-cell and myeloid differentiation. The ambiguous nature of leukemic blasts in ETP-ALL may lead to immunophenotypic alterations a...
The relatively poor mechanical properties of extruded modified double base (EMDB) propellants limit their range of applications. To overcome these drawbacks, a novel method was proposed to introduce glycidyl azide polymer-based energetic thermoplasti...
The Korean government is committed to advance the country’s energy transition to greener energy by increasing the share of renewable electricity to 20 percent by 2030 and to 30–35 percent by 2040. Achieving these goals will necessitate fl...
Epipolythiodioxopiperazines (ETPs), characterized by a diketopiperazine (DKP) core bridged by disulfide or polysulfide bonds, exhibit exceptional structural diversity and functional adaptability. This review comprehensively explores their multifacete...
Glycidyl azide polymer energetic thermoplastic elastomer (GAP-ETPE) has become a research hotspot due to its excellent comprehensive performance. In this paper, metastable intermolecular energetic nanocomposites (MICs) were prepared by a simple and s...
Glycidyl azide polymer-energetic thermoplastic elastomer propellant (GAP-ETPE) has high development prospects as a green solid propellant, although the preparation of GAP-ETPE with excellent performance is still a challenge. Focusing on the demand of...
Glycidyl azide polymer (GAP)–energetic thermoplastic elastomer (GAP-ETPE) propellants have high development prospects as green solid propellants, but the preparation of GAP-ETPEs with excellent performance is still a challenge. Improving the pe...
In order to study the temperature variation and flow characteristics in the twin-screw reactive extrusion process of synthetizing glycidyl azide polymer-based energetic thermoplastic elastomer (GAP-ETPE), a non-isothermal simulation and a safety anal...
Nanosecond laser ablation effectively modifies Cu-ETP copper surfaces by controlling wettability and microstructure. This study examines the effects of nanosecond fiber laser processing and subsequent oxidation on surface evolution. The analyzed para...
Clotting abnormalities are discussed both in the context with thyroid dysfunctions and obesity caused by a high fat diet. This study aimed to investigate the impact of hypo-, or hyperthyroidism on the endogenous thrombin potential (ETP), a master ind...
Accurate identification of equivalent thermal parameters (ETPs) is crucial for optimizing energy efficiency in residential buildings during winter electric heating. This study proposes a physics-informed neural network (PINN) approach to estimate ETP...
As a novel carbon material, multi-walled carbon nanotubes (MWCNTs) have attracted significant research interest in energetic applications due to their high aspect ratio and exceptional physicochemical properties. However, their inherent structural ch...
A wide range of immature acute leukemias (AL), ranging from acute myeloid leukemias with minimal differentiation to acute leukemias with an ambiguous lineage, i.e., acute undifferentiated leukemias and mixed phenotype acute leukemia with T- or B-plus...
To fully explore the metabolites of the mangrove endophytic fungus Penicillium janthinellum HDN13-309, which can produce Epipolythiodioxopiperazine (ETP) compounds with noteworthy anti-tumor activities, HPLC-MS analysis was applied, and five new glio...
Electrolytic tough pitch copper is commonly used in electric and electronic applications while fine copper wires are widely used in electronic conductors. A multi-pass wiredrawing process was designed for the manufacturing of fine pure copper wire, f...
This paper presents the results of research on a newly developed surface layer made by laser remelting the working surface of the Cu-ETP (CW004A, Electrolytic Tough Pitch) copper section insulator guide with Cr-Al powder. For the investigation, a fib...
The development of microelectronics results in higher demand for copper microwires and thin foils. Higher demand requires conducting research to obtain knowledge on the influence of extreme plastic deformation on materials’ susceptibility to pl...
The properties of copper in its solid state are strongly affected by the crystallization conditions of the liquid material. ETP grade copper (Electrolytic Tough Pitch Copper) contains oxygen, which causes Cu2O oxide to crystallize in the interdendrit...
To enhance the thermal decomposition properties of glycidyl azide polymer energetic thermoplastic elastomer (GAP-ETPE), the effects of nano-CuO supported on different carbon carriers (GO and CNT) were systematically investigated in this study. The st...
Conductive polymer gel materials are inherently susceptible to localized overheating during electrical heating owing to spatially nonuniform conductivity distributions, while their internal three-dimensional temperature fields remain challenging to m...
The continuous industrial development that occurs worldwide generates the need to develop new materials with increasingly higher functional properties. This need also applies to the basic material for electricity purposes, which is copper. In this ar...
Land-cover information is significant for land-use planning, urban management, and environment monitoring. This paper presented a novel extended topology-preserving segmentation (ETPS)-based multi-scale and multi-feature method using the convolutiona...
Within the 2,5-dioxopiperazine-containing natural products generated by “head-to-tail” cyclization of peptides, those derived from tryptophan allow further structural diversification due to the rich chemical reactivity of the indole heter...
In the original publication [...]
Early prediction of kidney graft function may assist clinical management, and for this, reliable non-invasive biomarkers are needed. We evaluated endotrophin (ETP), a novel non-invasive biomarker of collagen type VI formation, as a prognostic marker...
The new essential tremor (ET) classification defined ET-plus (ET-p) as an ET subgroup with additional neurological signs besides action tremor. While deep brain stimulation (DBS) is effective in ET, there are no studies specifically addressing DBS ef...
Potential evapotranspiration (ETp) and reference crop evapotranspiration (ETo) are two key parameters in hydrology, meteorology, and agronomy. ETp and ETo are related to each other but have different meanings and applications. In this study, the ETp...
This article applies the theoretical notion of “bounded rationality” to understand and to explain the updates of the Environmental Target Policy (ETP) in China during 1972–2016. An analytical framework is built up by combining the phase model and the...
In this work, titania (TiO2) nanoparticles modified by Eu(TTA)3Phen complexes (ETP) were prepared by a simple solvothermal method developing a fluorescence Mn7+ pollutant sensing system. The characterization results indicate that the ETP cause struct...
Potential evapotranspiration (ETp) is an important component of the water and energy cycle. This study investigated the changing patterns of both summer ETp and its drivers in the Huai River Basin for the first time using the newly proposed anomaly c...
Global warming may increase potential evapotranspiration (ETp), reducing the water resources in Yangzi River Delta. Therefore, it is important to investigate the trend of ETp there under the background of climate change. To this purpose, the systemat...
Evapotranspiration (ET) is one of the important components of the global hydrologic cycle, energy exchange, and carbon cycle. However, basin scale actual ET (hereafter ETa) is difficult to estimate accurately. We present an evaluation of four actual...
Lymphoblastic leukemia/lymphoma, a neoplasm of precursor B or T lineage lymphoid cells, usually involves the bone marrow and peripheral blood, and may involve nodal and/or extranodal sites. The diagnosis is based on morphologic assessment, immunophen...
In forming simulations, flow curves are cardinal inputs to predict features, such as forming forces and material flow. The laboratory-scale experiments to determine them, like compression or tensile tests, are affected by deformation heating, restric...
Intense urbanization, large scale industrialization and unprecedented population growth in the last few decades have been responsible for lowering environmental quality. Soil contamination with metals is a serious concern due to their toxicity and ab...
Industrial discharge of active pharmaceutical ingredients (APIs) into the environment in some middle- and low-income countries is not sufficiently regulated. The phytotoxicity of metronidazole (FLAGYL)—one of the most commonly used over the counter (...
To improve the reinforcement effect between a binder and high solid filler in a propellant formula, grafting the bonding group into the binder to form a neutral polymeric is a practically novel approach to improving the interface properties of the pr...
Paclitaxel (PTX), etoposide (ETP), and rapamycin (RAPA) have different mechanisms, allowing multiple pathways to be targeted simultaneously, effectively treating various cancers. However, these drugs have a low hydrosolubility, limiting clinical appl...
Background: Ovarian cancer is frequently diagnosed at an advanced stage and remains one of the most lethal gynecologic malignancies. The development of multidrug resistance (MDR) during repeated chemotherapy is a major cause of treatment failure and...
In the blending process of the composites, the clustering of MWCNTs under high concentration leads to poor dispersion and difficult complexing with luminescent elements. Cyanate ester resins (CERs) have a brittle network structure when cured caused b...
of 5