Molecular Cancer Biology
A section of Cancers (ISSN 2072-6694).
Section Information
Dysregulation of the complex biological processes that control cell and tissue homeostasis, growth and development under physiological conditions is the key driver of oncogenesis, tumor progression and therapy resistance of cancer. A better understanding of the pivotal molecular events underlying these three aspects of cancer biology will aid the identification of novel targets and the development of new therapeutic approaches for the treatment of this devastating disease. This section covers all aspects of molecular and cellular biology related to the development, progression and therapy of cancer. Topics of interest include:
- oncogenesis and cancer progression;
- cancer immunology;
- drug discovery and targeted therapy;
- tumor invasion and metastasis;
- cancer stem cell biology;
- genomic instability;
- DNA damage and repair;
- cell cycle regulation;
- hypoxia;
- cancer cell metabolism;
- mechanisms of therapy resistance;
- autophagy;
- apoptosis;
- necrosis;
- senescence;
- angiogenesis;
- inflammation and cancer
Editorial Board
Topical Advisory Panel
Special Issues
Following special issues within this section are currently open for submissions:
- Immune and Genetic Landscape of Lymph Nodes in Cancer (Deadline: 20 October 2023)
- Neuroendocrine Neoplasms: Current Challenges and Advances in the Biological Aspects, Diagnostic and Therapeutic Management (Volume II) (Deadline: 20 October 2023)
- Cancers Driven by HIF (Deadline: 20 October 2023)
- Molecular Biology of Colorectal Cancers (Deadline: 30 October 2023)
- Molecular Profiling, Detection, and Therapy of Squamous Cell Carcinomas (Deadline: 30 October 2023)
- Giant-Cell-Containing Tumors of Bone—New Insights into Pathobiology, the Clinical Setting and Targeted Therapies (Deadline: 31 October 2023)
- Glutamine Metabolism in the Onset and Progression of Tumorigenesis (Deadline: 31 October 2023)
- Alterations in Cis-Regulatory Elements and Non-Coding RNAs in Human Cancer (Deadline: 31 October 2023)
- Identification and Clinical Application of Immunological Receptors Targeting Mutated Antigens Expressed by Solid Tumors (Volume II) (Deadline: 31 October 2023)
- Advanced on Personalized Medicine of Cancers (Deadline: 31 October 2023)
- The Role of Chromosomal Instability in Cancer (Deadline: 31 October 2023)
- Involvement of RNA Polymerases I and III in Cancer Progression (Deadline: 31 October 2023)
- Diagnostics and Therapeutics Advances in Pancreatic Cancer (Deadline: 31 October 2023)
- The Response of Prostate Cancers to Androgen Deprivation Therapies (Deadline: 31 October 2023)
- Tumor Necrosis Factor: Molecular Insights and Clinical Implications (Deadline: 31 October 2023)
- NUTM1-Rearranged Neoplasia: Understanding an Expanding Family of Aggressive Cancers (Deadline: 31 October 2023)
- Molecular Mechanisms and Clinical Implications in Thoracic Cancers (Deadline: 1 November 2023)
- Single Cell RNA Sequencing in Breast Cancer (Deadline: 1 November 2023)
- Von Hippel-Lindau and Cancers (Deadline: 15 November 2023)
- Advances in Precision Medicine: Targeting Known and Emerging Oncogenic Targets in Lung Cancer (Deadline: 15 November 2023)
- MAPK/Akt Signaling Pathways: Function, Regulation, Signaling, and Implications for Cancer Treatment (Deadline: 15 November 2023)
- Cell Biology of Cancer Invasion (Deadline: 15 November 2023)
- Hematologic Malignancy (Second Edition) (Deadline: 17 November 2023)
- Signaling Pathways in Gliomas (Deadline: 20 November 2023)
- Genomic Characterization of Gynecological Cancer (Deadline: 20 November 2023)
- Genetics and Epigenetics of Leukemia and Lymphoma (Deadline: 23 November 2023)
- Mucins and Cancers (Deadline: 25 November 2023)
- Hepatocellular Cancer: Molecular Mechanisms, Diagnosis and Therapy (Deadline: 30 November 2023)
- The Study of Cancer Susceptibility Genes (Volume II) (Deadline: 30 November 2023)
- DNA Methylation Markers in Liquid Biopsies (Volume II) (Deadline: 30 November 2023)
- Genomics of Chronic Lymphocytic Leukemia (CLL) (Deadline: 30 November 2023)
- Immunogenic Cell Death and Associated Antitumor Immunity (Deadline: 30 November 2023)
- Early Age Onset Cancers (Deadline: 30 November 2023)
- Molecular and Genetic Diagnosis and Targeted Therapy of Myeloproliferative Neoplasms (Deadline: 30 November 2023)
- Updates on the Genetics of Myeloid Malignancies (Deadline: 30 November 2023)
- Molecular Mechanisms in Breast Cancer Therapy and Resistance (Deadline: 30 November 2023)
- BRCA-Associated Breast Cancer (Deadline: 15 December 2023)
- Proteogenomics Targeting Cervical Cancer (Deadline: 15 December 2023)
- Molecular Mechanisms and Clinical Implications of Pancreatic Cancer (Deadline: 20 December 2023)
- Targeting the PI3K–Akt–mTOR Pathway in Cancers: Impact on Tumor Cells and Their Microenvironments (Deadline: 25 December 2023)
- Immune System Pathways in Inflammatory Tumor Microenvironment and Carcinogenesis (Deadline: 29 December 2023)
- Androgen Receptor in Cancers: Not Only Prostate (Deadline: 30 December 2023)
- The Long Reach of the Retinoblastoma Tumor Suppressor Pathway (Deadline: 31 December 2023)
- Cellular Communication, Carcinogenesis and Targeted Interventions (Deadline: 31 December 2023)
- The Landscape of Transcriptomic Diversity in Oncology (Deadline: 31 December 2023)
- Metastatic Melanoma: From Gene Profiling to Targeted Therapy (Deadline: 31 December 2023)
- Oxidative Phosphorylation System Dysfunction Role and Mechanisms in Cancer and Its Therapies (Deadline: 31 December 2023)
- Pancreatic Neuroendocrine Tumors (Deadline: 31 December 2023)
- New Insights on the Hippo-YAP/TAZ-TEAD Pathway and Its Roles in Cancer (Deadline: 31 December 2023)
- New and Special Subtypes of Breast Cancer (Deadline: 31 December 2023)
- Molecular and Image Diagnosis in Endometrial Cancer 2024 (Deadline: 31 December 2023)
- Beyond JAK Inhibition: Molecular Pathogenesis and Novel Therapeutic Strategies for the Treatment of Myeloproliferative Neoplasms (MPNs) (Deadline: 31 December 2023)
- Zinc-Finger Proteins in Cancer (Deadline: 31 December 2023)
- Cell Signaling in Cancer and Cancer Therapy (Deadline: 31 December 2023)
- Colorectal Cancers: From Present Problems to Future Solutions Volume II (Deadline: 31 December 2023)
- Updates on the Molecular Profile of Gastrointestinal Stromal Tumors (Volume II) (Deadline: 31 December 2023)
- Novel Transcriptional Factors Regulating Cancer Stemness (Deadline: 31 December 2023)
- Targeting Channel Proteins in Cancer (Deadline: 15 January 2024)
- Molecular Mechanism in Wilms Tumor (Deadline: 15 January 2024)
- Lung Cancer: Molecular Pathways, Current Therapies and New Targeted Treatments (Deadline: 20 January 2024)
- Significance of KRAS Gene Mutations in Colorectal Cancer (Deadline: 25 January 2024)
- Genomics of Hematologic Cancers (Deadline: 31 January 2024)
- Novel Insights in Ocular and Orbital Oncology: From Molecular Biology to Treatment Strategies (Deadline: 31 January 2024)
- Lung Cancer—Molecular Insights and Targeted Therapies (Volume II) (Deadline: 31 January 2024)
- Molecular and Cellular Heterogeneity in an Evolving Tumor Landscape: When Diversity Gives Rise to Aggressive and Drug Resistant Cells (Deadline: 31 January 2024)
- Molecular Mechanisms in Head and Neck Cancer (Deadline: 31 January 2024)
- 2nd Edition: Estrogen Receptor-Positive (ER+) Breast Cancers (Deadline: 31 January 2024)
- The Biology of CD44 and Its Role in Cancer Progression: Therapeutic Implications (Deadline: 31 January 2024)
- Advances in Genetics and Epigenetics of Bladder Cancer (Deadline: 31 January 2024)
- Urology Cancers: Drug Resistance and Signaling Mechanism (Deadline: 1 February 2024)
- Advances in Cancer Glycobiology (Deadline: 5 February 2024)
- Sex Differences in Cancer (Deadline: 15 February 2024)
- Extracellular Metabolic Cues in the Regulation of Tumor Immune Environment (Deadline: 15 February 2024)
- Hodgkin Lymphoma (Volume II) (Deadline: 15 February 2024)
- Mechanisms of mRNA Translation in Pancreatic Cancer (Deadline: 20 February 2024)
- The Role of Cancer Stem Cells (CSCs) in Cancer Immunotherapy (Deadline: 23 February 2024)
- Gastric Cancers: Molecular Mechanisms, Novel Targets and Immunotherapies: From Bench to Clinical Therapeutics (Deadline: 28 February 2024)
- Combined Hepatocellular-Cholangiocarcinoma: An Update on Epidemiology, Classification, Diagnosis and Management (Deadline: 29 February 2024)
- The Recent Updates in Primary CNS Tumors (Deadline: 29 February 2024)
- Advances in Circulating Tumor Cells as a Liquid Biopsy for Cancers (Deadline: 29 February 2024)
- Autologous Stem Cell Transplantation or New Cellular Therapies for Neoplasias (Deadline: 29 February 2024)
- Mesenchymal Stem Cells: Key Players in Cancer Progression (Deadline: 1 March 2024)
- Genes in Cancer (Deadline: 1 March 2024)
- Brain Cancer Stem Cells in Children and Adults (Deadline: 1 March 2024)
- Nonlethal Functions of Caspases in Tumors (Deadline: 11 March 2024)
- Mechanisms of Therapy Resistance in Lung Cancer (Deadline: 15 March 2024)
- Growth Factors and Receptor Tyrosine Kinases in Development, Regeneration, and Tumorigenesis (Deadline: 15 March 2024)
- Time for a Paradigm Shift in Non-muscle-invasive Bladder Cancer (Volume II) (Deadline: 20 March 2024)
- Advances in Genetic and Molecular Approaches to Skin Cancer (Deadline: 30 March 2024)
- Multiple Signaling Pathways in Ovarian Cancer (Deadline: 31 March 2024)
- Molecular Genetics and Signaling Pathways in Liver Cancer (Deadline: 31 March 2024)
- Rare Gynecological Cancers (Deadline: 31 March 2024)
- Mitochondria as Targets for Cancer Therapy (Deadline: 31 March 2024)
- Mantle Cell Lymphoma: From Biology to Therapy (Deadline: 5 April 2024)
- Unlocking Novel Cancer Therapies through Targeting of the PI3K Pathway (Deadline: 5 April 2024)
- Glioblastoma: Advances in Molecular Insights and Therapeutic Strategies (Deadline: 10 April 2024)
- The Role of Ferroptosis in Cancer (Deadline: 10 April 2024)
- Factors Regulating Cancer Cell Growth, Migration, Invasion, and Apoptosis (Deadline: 15 April 2024)
- Drug Repurposing and Reformulation for Cancer Treatment (Deadline: 15 April 2024)
- Clinical Applications of Integrative Analysis of Validated Somatic and Germline Genomic Results in Oncology (Deadline: 25 April 2024)
- Natural Compounds in Cancers (Deadline: 30 April 2024)
- P53, EMT and DNA Repair: Novel Links Impacting Cancer Progression and Drug Response (Deadline: 30 April 2024)
- Mutations Driving Human Solid Tumors (Deadline: 30 April 2024)
- Advances in Molecular Oncology and Therapeutics (Deadline: 30 April 2024)
- New Treatments for Hepatobiliary Cancer (Deadline: 30 April 2024)
- Protein Kinases and Pseudokinases in Cancers (Deadline: 1 May 2024)
- Molecular Biology, Diagnosis and Management of Thyroid Cancer (Deadline: 1 May 2024)
- Drug Resistance in Colorectal Cancer (Deadline: 1 May 2024)
- The p53 Pathway in Cancer Research (Deadline: 24 May 2024)
- Epigenetic Modifications in Cancer Development (Deadline: 24 May 2024)
- Lung Cancer Proteogenomics: New Era, New Insights (Deadline: 30 May 2024)
- Inflammatory and Immunological Markers in Liver Cancers (Deadline: 31 May 2024)
- Deubiquitylating Enzymes and Their Contribution to Human Malignancies (Deadline: 31 May 2024)
- Cancer Genetics and Epigenetics: Their Roles and Clinical Implications (Deadline: 15 June 2024)
- Exosomes in Tumor (Deadline: 24 June 2024)
- Molecular Pathogenesis of Liver Cancers (Deadline: 30 June 2024)
- Molecular Insights into Drug Resistance in Cancer (Deadline: 30 June 2024)
- Research in MicroRNA Profiling of Prostate Cancer (Volume II) (Deadline: 30 June 2024)
- Liver Cancers Molecular Biomarkers Predicting Outcome (Deadline: 10 July 2024)
- The Metabolic Landscape of Gynecological Cancer: Identifying Targets for Therapeutic Intervention (Deadline: 31 July 2024)
- Neuroblastoma: Molecular Insights and Clinical Implications (Deadline: 15 August 2024)
- Molecular Alterations of Endometrial Cancer (Deadline: 20 August 2024)
- Molecular Targeted Therapy in Cancer (Deadline: 31 August 2024)
- Molecular Biology, Diagnosis and Management of Cervical Cancer (Deadline: 31 August 2024)
- The Duality of MYB: Normal and Cancer Cell Functions (Deadline: 20 September 2024)
- Transcription Factors in Breast Cancer (Deadline: 31 October 2024)
- Cutaneous Lymphoma (Deadline: 1 December 2024)
- Molecular Biology, Diagnosis and Management of Endometrial Cancer (Deadline: 12 July 2025)
Topical Collections
Following topical collections within this section are currently open for submissions:
- Circular RNAs: New Insights into the Molecular Biology of Cancer
- Genome Maintenance in Cancer Biology and Therapy
- Incorporating DNA Damage Response (DDR) Mechanisms in Cancer Systems
- miRNAs: New Insights in Tumor Biology
- Molecular Pathways in Cancers
- New Insights in the Genetics and Genomics of Adrenocortical Tumors and Pheochromocytomas
- Novel Biomarkers and Molecular Targets in Cancer
- Prostate Cancer—from Molecular Mechanisms to Clinical Care
- Recent Advances in Pancreatic Ductal Adenocarcinoma
- Recent Advances in Tumor Suppressor (Closed)
- Regulatory and Non-Coding RNAs in Cancer Epigenetic Mechanisms
- Role of Stromal Cells in Determining Tumor and Cancer Stem Cell Behaviors and Therapeutic Response
- Stemness and Drug-Persistence in Cancer
- Tumor Evolution: Progression, Metastasis and Therapeutic Response