Molecular Cancer Biology
A section of Cancers (ISSN 2072-6694).
Section Information
Dysregulation of the complex biological processes that control cell and tissue homeostasis, growth and development under physiological conditions is the key driver of oncogenesis, tumor progression and therapy resistance of cancer. A better understanding of the pivotal molecular events underlying these three aspects of cancer biology will aid the identification of novel targets and the development of new therapeutic approaches for the treatment of this devastating disease. This section covers all aspects of molecular and cellular biology related to the development, progression and therapy of cancer. Topics of interest include:
- oncogenesis and cancer progression;
- cancer immunology;
- drug discovery and targeted therapy;
- tumor invasion and metastasis;
- cancer stem cell biology;
- genomic instability;
- DNA damage and repair;
- cell cycle regulation;
- hypoxia;
- cancer cell metabolism;
- mechanisms of therapy resistance;
- autophagy;
- apoptosis;
- necrosis;
- senescence;
- angiogenesis;
- inflammation and cancer
Editorial Board
Topical Advisory Panel
Special Issues
Following special issues within this section are currently open for submissions:
- Cellular Plasticity, Metabolic Adaptations and Therapeutic Strategies in Breast Cancer (Deadline: 30 July 2026)
- Flow Cytometry and Molecular Studies in Hematological Malignancies (Deadline: 30 July 2026)
- Novel Advances in the Molecular Understanding of Myeloproliferative Neoplasms (MPNs) (Deadline: 31 July 2026)
- Mitochondrial Metabolism and Cancer (Deadline: 31 July 2026)
- The Molecular Biology of Cholangiocarcinoma (Deadline: 31 July 2026)
- Novel Genomic Strategies for Personalized Cancer Treatment (Deadline: 31 July 2026)
- The Tumorigenesis Mechanism of Breast Cancer (Deadline: 10 August 2026)
- Advances in Precision Medicine: Targeting Known and Emerging Oncogenic Targets in Lung Cancer (2nd Edition) (Deadline: 15 August 2026)
- Proteometabolomics in Cancer (Deadline: 30 August 2026)
- Transcription Factors and Their Involvement in Carcinogenesis (Deadline: 30 August 2026)
- mTOR Signaling in Cancer (Deadline: 31 August 2026)
- Cytoskeleton in Tumor Growth and Progression (Deadline: 31 August 2026)
- Epigenetic Markers of Cancer Diseases (Deadline: 31 August 2026)
- Feature Review Paper Special Issue in Section Molecular Cancer Biology (Deadline: 31 August 2026)
- Cancer Stem Cells: The Origin of Tumor Relapse and Metastasis (Deadline: 31 August 2026)
- Host-Related Prognostic Factors in Gastrointestinal Malignancies: From Genetics to Phenomics (Deadline: 31 August 2026)
- Role of TP53 Mutation in Cancer (Deadline: 31 August 2026)
- Role of Iron Metabolism in Tumor Progression (Deadline: 25 September 2026)
- The Molecular Mechanisms of DNA Replication and Repair (Deadline: 30 September 2026)
- Targeting JAK/STAT Signaling Pathways for Studying Cancer Pathogenesis, Discovering Cancer Markers, Developing Therapies, and Bypassing Drug Resistance (Deadline: 30 September 2026)
- Translational Advances in Reproductive Cancers: From Targets to Therapies (Deadline: 30 September 2026)
- Epigenomic and Transcriptional Mechanisms in Cancer Progression and Therapy Response (Deadline: 30 September 2026)
- Pre-Clinical Studies of Personalized Medicine for Cancer Research: 2nd Edition (Deadline: 30 September 2026)
- Roles of Circular RNAs (circRNAs) in Cancer Development and Progression (Deadline: 30 September 2026)
- Non-Coding RNAs in Cancer: Molecular Diagnostics and RNA-Based Therapeutics (Deadline: 30 September 2026)
- Senescence and Cell Plasticity in Cancer Development (Deadline: 30 September 2026)
- The Cellular Ecosystem of Cancer: New Insights into Cell Biology (Deadline: 30 September 2026)
- The Evolving Landscape of Endometrial Cancer (Deadline: 30 September 2026)
- Cellular and Molecular Mechanisms of Malignant Nervous System Cancers (Deadline: 30 September 2026)
- Lung Cancer—Molecular Insights and Targeted Therapies (Third Edition) (Deadline: 30 September 2026)
- Cell Cycle Dysregulation in Cancers (Deadline: 30 September 2026)
- State-of-the-Art Research on Molecular and Cellular Mechanisms of Glioblastoma (Deadline: 6 October 2026)
- RAS Pathways in Cancer Cells (Deadline: 15 October 2026)
- Genetic and Molecular Characterization of Lung Cancer (Deadline: 15 October 2026)
- A Renewed Understanding of Tumor Growth Modulation by Tumor Necrosis Factor (TNF)-Associated Pathways (Deadline: 15 October 2026)
- MYC Oncogene in Cancer: Cancer Cell Intrinsic and Immune Inhibitory Functions (Deadline: 30 October 2026)
- The Role of Sphingolipids in Cancer Progression (Deadline: 30 October 2026)
- Epigenetic Modifiers in Cancer Treatment: Molecular Mechanisms and Clinical Applications (Deadline: 30 October 2026)
- Signaling Networks and Systems Biology in Cancer (Deadline: 31 October 2026)
- Genetic Disorders and Cancer Susceptibility: Molecular Mechanisms, Risk Assessment and Targeted Therapies (Deadline: 31 October 2026)
- Molecular Biology, Diagnosis and Management of Endometrial Cancer (Deadline: 31 October 2026)
- Metabolic Reprogramming in Cancer: Implications for Tumor Progression, Metastasis, Immune Evasion and Therapy Resistance (Deadline: 31 October 2026)
- Molecular Biology for Germ Cell Tumors (Deadline: 31 October 2026)
- New Perspectives on Claudins and Tight Junction Complexes: From Membrane Architecture to Targeted Cancer Therapy (Deadline: 1 November 2026)
- Molecular and Genetic Diagnosis and Targeted Therapy of Myeloproliferative Neoplasms (2nd Edition) (Deadline: 15 November 2026)
- Oncogenesis of Lymphoma (2nd Edition) (Deadline: 15 November 2026)
- Advances in Molecular Mechanisms of Gastrointestinal Tumors (2nd Edition) (Deadline: 25 November 2026)
- The Role of Cysteine Cathepsins in Cancer Progression (Deadline: 26 November 2026)
- HMGA Oncoproteins in Cancer (Deadline: 30 November 2026)
- Oncoproteins in Cancers: Transcriptional Regulation, Signaling and Targeted Therapy (Deadline: 30 November 2026)
- Targeted Therapy in Glioblastoma and Glioma (Deadline: 30 November 2026)
- The Role of Ferroptosis in Cancer (2nd Edition) (Deadline: 30 November 2026)
- Hippo/YAP Signaling Pathways in Cancers (Deadline: 30 November 2026)
- Cellular Senescence in Cancer: Therapeutic Induction, Microenvironmental Crosstalk and Clinical Implications (Deadline: 30 November 2026)
- Epigenetic Alterations in Human Tumors (Deadline: 30 November 2026)
- Tumor Heterogeneity in Breast Cancer—the “Omics” Revolution (Deadline: 30 November 2026)
- The Emerging Role of Extracellular Vesicles and Mitochondria in Cancer (Deadline: 1 December 2026)
- Myelodysplastic Neoplasms (MDS) and Myelodysplastic/ Myeloproliferative Neoplasms (MDS/MPN): New Insights into Diagnosis and Targeted Therapy (Deadline: 15 December 2026)
- Multilevel Molecular Regulation in Cancer: From Epigenetics to Signaling Pathways and Therapeutic Targets (Deadline: 15 December 2026)
- Cancer Genetics and Epigenetics: Their Roles and Clinical Implications (2nd Edition) (Deadline: 20 December 2026)
- Genetic Predisposition to Hematological Malignancies (Deadline: 20 December 2026)
- Cancer Cell Death and Immune Response (Deadline: 25 December 2026)
- Castration- and Therapy-Resistant Prostate Cancer: Biomarkers, Therapeutic Targets, and Emerging Approaches (Deadline: 30 December 2026)
- Advancements in Molecular Research of Prostate Cancer (2nd Edition) (Deadline: 31 December 2026)
- Autophagy and Apoptosis in Cancer Progression (Deadline: 31 December 2026)
- BRCA1 and BRCA2 Pathogenic Variants: Cancer Risk and Genetic Testing (Deadline: 31 December 2026)
- Cancer Cell Vulnerabilities on Pathways Regulating the Cell Cycle (Deadline: 31 December 2026)
- Roles of Urokinase Receptors in Cell Biology: Modulating Tumor Cell Migration and Invasion (Deadline: 31 December 2026)
- Mutagenesis and DNA Methylation in Aging (Deadline: 31 December 2026)
- Novel Strategies to Fight Metastatic Breast Cancer (Deadline: 31 December 2026)
- Long-Read Sequencing in Cancer (2nd Edition) (Deadline: 31 December 2026)
- Genetic Alterations and Features in the Development of Gastrointestinal Cancer (Deadline: 31 December 2026)
- Tumor Suppressor Genes and Oncogenes: Genome-Wide Insights into Cancer Biology (Deadline: 31 December 2026)
- Molecular Advances in Lung Cancer: From Pathogenesis to Precision Therapy (2nd Edition) (Deadline: 31 December 2026)
- Intercepting Genitourinary Cancers: Emerging Targets and Promising Interventions (Deadline: 31 December 2026)
- Overcoming the Barriers: Cellular and Molecular Pathology of Pancreatic Cancer (Deadline: 31 December 2026)
- Single-Cell Biology of Cancer (Deadline: 31 December 2026)
- Genomic and Epigenomic Aberrations in Cancer (Deadline: 31 December 2026)
- The Function of the MYC Network in Normal and Neoplastic Tissues (Deadline: 1 January 2027)
- Metals in Cancer: From Molecular Mechanisms to Innovative Therapeutics (Deadline: 31 January 2027)
- Blood Stem Cell and Hematological Malignancies (Second Edition) (Deadline: 31 January 2027)
- Advances in Molecular Biology and Genetics of Prostate Cancer (Deadline: 31 January 2027)
- Molecular and Genetic Drivers of Cancer: Organelle Dysfunction, Cancer Stem Cells, and Tumor Progression (Deadline: 31 January 2027)
- Advances in Targeted Therapies and Pharmacogenomics of Leukemia (Deadline: 20 February 2027)
- The Role of Peptidases in Cancer (Deadline: 25 February 2027)
- Emerging Roles of HDACs in Cancer Metabolism, Plasticity and Therapeutic Response (Deadline: 28 February 2027)
- Signaling Molecules for Brain Tumors (Deadline: 28 February 2027)
- The Roles of microRNAs and Long Non-Coding RNAs in Cancer (Deadline: 28 February 2027)
- Proteogenomics of Lung, Thoracic and Breast Cancers: Enter the Era of Precision Oncology (Deadline: 31 March 2027)
- Molecular Mechanisms of Resistance to Cancer Therapies (Deadline: 31 March 2027)
- Pathological and Spatial Insights into Pancreatic Cancer Biology (Deadline: 31 July 2027)
Topical Collections
Following topical collections within this section are currently open for submissions: