Molecular Cancer Biology
A section of Cancers (ISSN 2072-6694).
Section Information
Dysregulation of the complex biological processes that control cell and tissue homeostasis, growth and development under physiological conditions is the key driver of oncogenesis, tumor progression and therapy resistance of cancer. A better understanding of the pivotal molecular events underlying these three aspects of cancer biology will aid the identification of novel targets and the development of new therapeutic approaches for the treatment of this devastating disease. This section covers all aspects of molecular and cellular biology related to the development, progression and therapy of cancer. Topics of interest include:
- oncogenesis and cancer progression;
- cancer immunology;
- drug discovery and targeted therapy;
- tumor invasion and metastasis;
- cancer stem cell biology;
- genomic instability;
- DNA damage and repair;
- cell cycle regulation;
- hypoxia;
- cancer cell metabolism;
- mechanisms of therapy resistance;
- autophagy;
- apoptosis;
- necrosis;
- senescence;
- angiogenesis;
- inflammation and cancer
Editorial Board
Topical Advisory Panel
Special Issues
Following special issues within this section are currently open for submissions:
- The Role of Apoptosis and Autophagy in Cancer (Deadline: 31 July 2025)
- Mesothelioma—From Diagnosis to Treatment (Deadline: 31 July 2025)
- Exploring the Genetic and Epigenetic Factors in Leukemia and Lymphoma (Deadline: 31 July 2025)
- Cancer Induced Organ Dysfunctions (Cachexia) (Deadline: 31 July 2025)
- Molecular and Cellular Heterogeneity in an Evolving Tumor Landscape: When Diversity Gives Rise to Aggressive and Drug-Resistant Cells (2nd Edition) (Deadline: 31 July 2025)
- Transcription Factors in Breast Cancer (Deadline: 31 July 2025)
- Exploiting Liabilities in Mechanism of DNA Repair for Cancer Therapy (Deadline: 31 July 2025)
- Alternative Cell Death Modes in Regulating Cancer Stem Cells and Therapeutic Strategies (Deadline: 10 August 2025)
- Cell Migration and Invasion in Cancer (Deadline: 20 August 2025)
- From Genomics and Immunogenomics to Treatments of Head and Neck Cancer (2nd Edition) (Deadline: 31 August 2025)
- Neuroscience of Brain Tumors (Deadline: 31 August 2025)
- Lymphoid and Myeloid Leukemias—Current Progress in Biology and Treatment (Deadline: 31 August 2025)
- Cutaneous Lymphoma (Deadline: 31 August 2025)
- Progress in Modelling, Understanding of Cellular Biology of Prostate Cancer (Deadline: 31 August 2025)
- Genetic and Epigenetic Markers in Gliomas: Expanding the Horizon in Diagnosing, Predicting, and Treating Gliomas (Deadline: 1 September 2025)
- Oxidative Stress and Cancer: Possible Beneficial and Antioxidant Strategies (2nd Edition) (Deadline: 15 September 2025)
- Cancer Genetics and Epigenetics: Their Roles and Clinical Implications (Deadline: 15 September 2025)
- Genomics and Transcriptomics in Sarcoma (Deadline: 25 September 2025)
- Feature Review Paper Special Issue in Section Molecular Cancer Biology (Deadline: 30 September 2025)
- Advancements and Treatment Strategies for Central Nervous System Malignancies and Cancer Stem Cells (Deadline: 30 September 2025)
- Chronic Lymphocytic Leukemia: From Genetics and Epigenetics to Therapy (Deadline: 30 September 2025)
- Giant-Cell-Containing Tumors of Bone—New Insights into Pathobiology, the Clinical Setting and Targeted Therapies (Deadline: 30 September 2025)
- EGFR Signaling in Cancer (2nd Edition) (Deadline: 30 September 2025)
- Cellular and Molecular Mechanisms of Malignant Nervous System Cancers (Deadline: 1 October 2025)
- 3D Cultures and Organoids in Cancer Research (Deadline: 1 October 2025)
- The Genomic Landscape of Gynecological Cancers (Deadline: 1 October 2025)
- The Role of Chromosomal Instability in Cancer: 2nd Edition (Deadline: 1 October 2025)
- Protein Structure and Cancer—2nd Edition (Deadline: 20 October 2025)
- Molecular Mechanisms in Head and Neck Cancer (Deadline: 31 October 2025)
- Molecular Genetics, Signaling Pathways, and Therapeutic Strategies for Liver Cancer (Deadline: 31 October 2025)
- Advances in Uveal Melanoma (Deadline: 31 October 2025)
- Childhood Cancer in the Genomic Era: Experimental and Theoretical Approaches (2nd Edition) (Deadline: 31 October 2025)
- MicroRNA (miRNA) in Cancers (Deadline: 31 October 2025)
- Oncoproteins in Cancers: Transcriptional Regulation, Signaling and Targeted Therapy (Deadline: 10 November 2025)
- Advances in Pleural and Peritoneal Mesothelioma (Deadline: 10 November 2025)
- Genetics in Hematological Malignancies (Deadline: 10 November 2025)
- Advances in Molecular Mechanisms of Gastrointestinal Tumors (2nd Edition) (Deadline: 25 November 2025)
- Gastric Cancers: Molecular Mechanisms, Novel Targets and Immunotherapies: From Bench to Clinical Therapeutics (2nd Edition) (Deadline: 30 November 2025)
- Epigenetics in Cancer and Drug Therapeutics (Deadline: 30 November 2025)
- Molecular Pathways in Cancers (2nd Edition) (Deadline: 30 November 2025)
- Integrin Beta-1 Signaling in Cancers (Deadline: 30 November 2025)
- Growth Factors and Receptor Tyrosine Kinases in Development, Regeneration, and Tumorigenesis: 2nd Edition (Deadline: 30 November 2025)
- Recent Advances in the Molecular Genetics of Sarcomas (Deadline: 30 November 2025)
- Incorporating DNA Damage Response (DDR) Mechanisms in Cancer Systems: 2nd Edition (Deadline: 15 December 2025)
- Advances in Genomics and Molecular Diagnostics in Gynecological Pathology (Deadline: 15 December 2025)
- Cytokine and Growth Factor Signaling at the Interface between Immune Cells and Cancer (Deadline: 30 December 2025)
- Natural Compounds in Cancers: 2nd Edition (Deadline: 31 December 2025)
- Molecular Mechanisms in Bone and Soft Tissue Sarcomas (Deadline: 31 December 2025)
- Precision Oncology for Rare Skin Cancers (Deadline: 31 December 2025)
- Advances in the Molecular Biology of Sarcoma and Drug Development (Deadline: 31 December 2025)
- Technological Development for Advances in Cancer Research and Precision Oncology (Deadline: 31 December 2025)
- Molecular Biology, Diagnosis and Management of Cervical Cancer (Deadline: 31 December 2025)
- Novel Advances in the Molecular Understanding of Myeloproliferative Neoplasms (MPNs) (Deadline: 15 January 2026)
- Cervical Cancer: Study on Molecular Landscape and Protein Biomarkers. Current Diagnostic and Therapeutic Capabilities (Deadline: 15 January 2026)
- Cancer Cell Vulnerabilities on Pathways Regulating the Cell Cycle (Deadline: 20 January 2026)
- Recent Advances in the Molecular Biology of Urologic Cancers: Integrative Insights from Pathogenesis to Clinical Applications (Deadline: 31 January 2026)
- The Cancer Stem Cells and the Quiescence (Deadline: 31 January 2026)
- Breast Cancer and Stem Cells (Deadline: 31 January 2026)
- The Biology of Hepatocellular Carcinoma: Implications for Genomic and Immune Therapies (2nd Edition) (Deadline: 31 January 2026)
- Advances in Precision Medicine: Targeting Known and Emerging Oncogenic Targets in Lung Cancer (2nd Edition) (Deadline: 15 February 2026)
- Fibroblasts as Playmakers of Cancer Progression: Current Knowledge and Future Perspectives (2nd Edition) (Deadline: 20 February 2026)
- Molecular Tumor Boards: Promise and Limitations for Personalized Cancer Therapy: 2nd Edition (Deadline: 20 February 2026)
- MYC Oncogene in Cancer: Cancer Cell Intrinsic and Immune Inhibitory Functions (Deadline: 28 February 2026)
- Advances in Choroidal Melanoma: From Treatment to Prognosis (Deadline: 28 February 2026)
- The Genetics of Head and Neck Squamous Cell Carcinoma (Deadline: 28 February 2026)
- Molecular Pathology of Brain Tumors (Deadline: 15 March 2026)
- Roles of Urokinase Receptors in Cell Biology: Modulating Tumor Cell Migration and Invasion (Deadline: 28 March 2026)
- Lipids and Small Metabolites in Cancer—2nd Edition (Deadline: 31 March 2026)
- Proteomics in Skin Cancer: Recent Advances (Deadline: 31 March 2026)
- Novel Strategies to Fight Metastatic Breast Cancer (Deadline: 31 March 2026)
- Gene Fusions in Cancer (Deadline: 31 March 2026)
- Lung Cancer—Molecular Insights and Targeted Therapies (Third Edition) (Deadline: 31 March 2026)
- Glioblastoma Stem Cells: Molecule Pathways and Cancer Therapy (Deadline: 31 March 2026)
- Significance of KRAS Gene Mutations in Colorectal Cancer (2nd Edition) (Deadline: 31 March 2026)
- Intratumoral Heterogeneity in Brain Cancers (Deadline: 31 March 2026)
- The Role of Regulatory Non-Coding RNA in Cancer (2nd Edition) (Deadline: 4 April 2026)
- Clinical Applications of Integrative Analysis of Validated Somatic and Germline Genomic Results in Oncology (Deadline: 25 April 2026)
- Advancements in Molecular Research of Prostate Cancer (Deadline: 30 April 2026)
- PARP Inhibitors in Cancers: 2nd Edition (Deadline: 30 April 2026)
- The Role of Ferroptosis in Cancer (2nd Edition) (Deadline: 30 April 2026)
- Neuroblastoma: Molecular Insights and Clinical Implications (Deadline: 30 April 2026)
- Advances in Molecular and Genetic Biomarkers in Head and Neck Squamous Cell Carcinoma (Deadline: 30 April 2026)
- Cell Adhesion in Human Cancer (Deadline: 1 May 2026)
- Molecular and Genetic Diagnosis and Targeted Therapy of Myeloproliferative Neoplasms (2nd Edition) (Deadline: 15 May 2026)
- Mutagenesis and DNA Methylation in Aging (Deadline: 31 May 2026)
- Looking for New Biochemical Mechanisms in Cancer: The New Dawn in the Omics Sciences (Deadline: 1 June 2026)
- Application of Large-Scale Genome Data in Identifying Clinically Actionable Targets in Cancer (Deadline: 15 June 2026)
- Advances in Neurofibromatosis (Deadline: 30 June 2026)
- Long-Read Sequencing in Cancer (2nd Edition) (Deadline: 30 June 2026)
- Genetic Alterations and Features in the Development of Gastrointestinal Cancer (Deadline: 30 June 2026)
- Cancer Stem Cells: The Origin of Tumor Relapse and Metastasis (Deadline: 31 August 2026)
Topical Collections
Following topical collections within this section are currently open for submissions:
- Cell Signaling in Cancer and Cancer Therapy
- Factors Regulating Cancer Cell Growth, Migration, Invasion, and Apoptosis
- Genome Maintenance in Cancer Biology and Therapy (Closed)
- Incorporating DNA Damage Response (DDR) Mechanisms in Cancer Systems (Closed)
- miRNAs: New Insights in Tumor Biology (Closed)
- Molecular Pathways in Cancers (Closed)
- New Insights in the Genetics and Genomics of Adrenocortical Tumors and Pheochromocytomas (Closed)
- Novel Biomarkers and Molecular Targets in Cancer (Closed)
- Prostate Cancer—from Molecular Mechanisms to Clinical Care
- Recent Advances in Pancreatic Ductal Adenocarcinoma
- Regulatory and Non-Coding RNAs in Cancer Epigenetic Mechanisms
- Role of Stromal Cells in Determining Tumor and Cancer Stem Cell Behaviors and Therapeutic Response
- Stemness and Drug-Persistence in Cancer
- Tumor Evolution: Progression, Metastasis and Therapeutic Response
