Molecular Cancer Biology
A section of Cancers (ISSN 2072-6694).
Section Information
Dysregulation of the complex biological processes that control cell and tissue homeostasis, growth and development under physiological conditions is the key driver of oncogenesis, tumor progression and therapy resistance of cancer. A better understanding of the pivotal molecular events underlying these three aspects of cancer biology will aid the identification of novel targets and the development of new therapeutic approaches for the treatment of this devastating disease. This section covers all aspects of molecular and cellular biology related to the development, progression and therapy of cancer. Topics of interest include:
- oncogenesis and cancer progression;
- cancer immunology;
- drug discovery and targeted therapy;
- tumor invasion and metastasis;
- cancer stem cell biology;
- genomic instability;
- DNA damage and repair;
- cell cycle regulation;
- hypoxia;
- cancer cell metabolism;
- mechanisms of therapy resistance;
- autophagy;
- apoptosis;
- necrosis;
- senescence;
- angiogenesis;
- inflammation and cancer
Editorial Board
Topical Advisory Panel
Special Issues
Following special issues within this section are currently open for submissions:
- Signaling by Lysophosphatidic Acid, Sphingosine 1-Phosphate, and Other Lysophospholipids in Cancers (Deadline: 30 May 2022)
- Resistance Mechanisms in Malignant Brain Tumors (Deadline: 31 May 2022)
- Salivary Gland Adenoid Cystic Carcinoma (Deadline: 31 May 2022)
- The Role of SBRT/SABR in Prostate Cancer Radiotherapy (Deadline: 31 May 2022)
- Epigenetic Dysregulation in Melanoma (Deadline: 31 May 2022)
- Targeted Therapy Based on Cancer Genomics (Deadline: 31 May 2022)
- Mitochondria and Metabolism of Pancreatic Adenocarcinoma Cells (Deadline: 31 May 2022)
- Understanding New Therapeutic Options and Promising Predictive Biomarkers for Lung Cancer Patients. A Selection of Papers from the Third Joint Meeting on Lung Cancer of the FHU OncoAge (Nice, France) and the MD Anderson Cancer Center (Houston, TX, USA) (Deadline: 31 May 2022)
- The Roles of microRNAs in Cancer Aggressiveness and Drug Resistance (Deadline: 31 May 2022)
- Signalling Pathways of Cancer Stem Cells (Deadline: 1 June 2022)
- Molecular Pathogenesis and Management of Anaplastic Large Cell Lymphoma (Deadline: 1 June 2022)
- Understanding Molecular Regulation of Cancer Progression and Metastasis (Deadline: 10 June 2022)
- New Insights on Genomics in Thyroid Cancers: Impact on Diagnosis, Prognosis and Therapy (Deadline: 15 June 2022)
- TGF-β Signaling in Squamous Cell Carcinoma (Deadline: 15 June 2022)
- Molecular Mechanisms Underlying Cancer Prevention and Intervention with Bioactive Food Components (Deadline: 30 June 2022)
- Targeting the (Un)Usual Suspects in Cancer (Deadline: 30 June 2022)
- Signaling Pathways in Breast Cancer (Deadline: 30 June 2022)
- Molecular Mechanisms Underlying Tumor Onset and Progression in Liver Cancers (Deadline: 30 June 2022)
- The Role and Therapeutic Target Potential of RBPs in Cancer (Deadline: 30 June 2022)
- Telomere Biology and Its Role in Cancer Progression: From Basic Science to Application (Deadline: 30 June 2022)
- Protein Synthesis in Cancer Cells: Mechanisms and Novel Targeted Therapies (Deadline: 30 June 2022)
- Causes and Consequences of Chromosomal Instability in Cancer (Deadline: 30 June 2022)
- The Pivotal Role of Lipids in Cancer Pathophysiology, Diagnosis and Therapy (Deadline: 30 June 2022)
- Recent Advances in Carcinogenesis Transcription Factors: Biomarkers and Targeted Therapies (Deadline: 30 June 2022)
- Anti-HER2 Therapy Resistance in Breast Cancer (Deadline: 30 June 2022)
- CRISPR/Cas9 in Cancer Research (Deadline: 30 June 2022)
- New Insights into Hereditary Cancer Syndromes (Deadline: 30 June 2022)
- Analyze Cancer Screening and Make Predictions and Prognoses Using Biomarkers (Deadline: 1 July 2022)
- Peripheral T-cell Lymphoma: From Biological Research to New Therapies (Deadline: 10 July 2022)
- Cancer Metastasis Models (Deadline: 15 July 2022)
- The Role of Hedgehog Pathway in Cancer (Deadline: 20 July 2022)
- Mutations Driving Human Solid Tumors (Deadline: 20 July 2022)
- Research in MicroRNA Profiling of Prostate Cancer (Deadline: 31 July 2022)
- Advances in Aggressive Subtypes of Cancers Caused by Inherited Mutations in DNA Damage Repair Genes (Deadline: 31 July 2022)
- Circular RNAs: New Insights into the Molecular Biology of Cancer (Deadline: 31 July 2022)
- Cell Plasticity in Cancer Progression: Role of EMT, Epigenetic Regulation and Host Microenvironment (Deadline: 31 July 2022)
- The Role of Plasminogen Receptors in Cancers (Deadline: 1 August 2022)
- Genomic Landscape of Breast Cancer: From Primary to Metastasis (Deadline: 10 August 2022)
- Cancer Drug Resistance: An Epigenetic Approach (Deadline: 15 August 2022)
- Mechanism Underlying Tumor Relapse and Targeted Treatment Strategies (Deadline: 15 August 2022)
- Targeting the PI3K–Akt–mTOR Pathway in Cancers: Impact on Tumor Cells and Their Microenvironments (Deadline: 20 August 2022)
- Alterations in Cis-Regulatory Elements in Human Cancer (Deadline: 31 August 2022)
- Skull Base Tumours (Deadline: 31 August 2022)
- Phase Separation, Chromatin Organization and Transcription for Cancers (Deadline: 1 September 2022)
- Exploring Novel Biological Rationales for the Design of Next-Generation Combination Therapies (Deadline: 15 September 2022)
- Hodgkin Lymphoma (Deadline: 15 September 2022)
- Molecular and Cellular Heterogeneity in an Evolving Tumor Landscape: When Diversity Gives Rise to Aggressive and Drug Resistant Cells (Deadline: 15 September 2022)
- New Insights into the Molecular Mechanism of Epithelial Plasticity in Cancer (Deadline: 15 September 2022)
- Notch Signaling Pathway in Cancers (Deadline: 15 September 2022)
- Omics in Ovarian Cancer (Deadline: 15 September 2022)
- Updates on the Molecular Profile of Gastrointestinal Stromal Tumors (Deadline: 20 September 2022)
- Genomic Instability and How to Exploit It for Cancer Cell Vulnerability (Deadline: 22 September 2022)
- Molecular Mechanism of the Interaction Between Cells and Extracellular Matrix in Cancer Progression (Deadline: 30 September 2022)
- Metabolic Alterations in Cancer (Deadline: 30 September 2022)
- Von Hippel-Lindau and Cancers (Deadline: 30 September 2022)
- Updates on Molecular Targeted Therapies for CNS Tumors (Deadline: 30 September 2022)
- Autologous Stem Cell Transplantation or New Cellular Therapies for Neoplasias (Deadline: 30 September 2022)
- Translational Research of Liver Cancer (Deadline: 14 October 2022)
- Precision Medicine in Thoracic Oncology (Deadline: 15 October 2022)
- Tumor Necrosis Factor: Molecular Insights and Clinical Implications (Deadline: 15 October 2022)
- Metabolic Rewiring in Cancer (Deadline: 31 October 2022)
- Involvement of RNA Polymerases I and III in Cancer Progression (Deadline: 31 October 2022)
- Cancer Cell Metabolism, Glycolysis, Lactate Production and Transport and Potential Therapeutic Options for Inhibitors (Deadline: 1 November 2022)
- Gene Expression Regulation of Long Non-coding RNAs in Cancer (Deadline: 15 November 2022)
- MAPK/Akt Signaling Pathways: Function, Regulation, Signaling, and Implications for Cancer Treatment (Deadline: 15 November 2022)
- Feature Review Papers on Gastroesophageal Junction and Gastric Cancers (Deadline: 15 November 2022)
- Uncovering the Diversity of Form and Function for Long Non-coding RNAs in Lung Cancer (Deadline: 15 November 2022)
- Adhesive Networks in Cancer (Deadline: 15 November 2022)
- Dysregulated Acetylation/Deacetylation Cycles as Oncogenic Drivers and Drug Targets in Cancer (Deadline: 30 November 2022)
- Molecular Signatures in Head and Neck Cancer (Deadline: 30 November 2022)
- Novel Insights into the Molecular Mechanisms of Treatment Resistance and Predictive Biomarkers in Metastatic Prostate Cancer (Deadline: 30 November 2022)
- Drug Repurposing and Reformulation for Cancer Treatment (Deadline: 30 November 2022)
- Protein Kinases and Pseudokinases in Cancers (Deadline: 1 December 2022)
- Molecular Characterization of Renal Cell Carcinoma (Deadline: 1 December 2022)
- Hippo Signaling Pathway in Cancers (Deadline: 15 December 2022)
- Biological Relevance and Therapeutic Potential of G-Quadruplexes in Cancer (Deadline: 15 December 2022)
- BRCA-Associated Breast Cancer (Deadline: 20 December 2022)
- Combined Hepatocellular-Cholangiocarcinoma: An Update on Epidemiology, Classification, Diagnosis and Management (Deadline: 31 December 2022)
- The Analysis of Circulating Tumor Cells (CTCs): A New Insights into the Biology of Cancers (Deadline: 31 December 2022)
- Advances in Molecular Pathology and Biology of Soft Tissue and Bone Tumors (Deadline: 31 December 2022)
- Diagnostics and Therapeutics Advances in Pancreatic Cancer (Deadline: 31 December 2022)
- Chronic Liver Disease and Hepatocellular Carcinoma Biomarkers (Deadline: 31 December 2022)
- The Biological Mechanism of Cancer Proliferation and Metastasis (Deadline: 15 January 2023)
- Zinc-Finger Proteins in Cancer (Deadline: 30 January 2023)
- Immunogenic Cell Death and Associated Antitumor Immunity (Deadline: 31 January 2023)
- Telomeres in Cancer Research (Deadline: 31 January 2023)
- Innovations in Soft Tissue Sarcoma Diagnosis and Treatment (Deadline: 31 January 2023)
- Advances in Genomics and Molecular Pathology of Rare Cancers — Focus on Diverse Populations (Deadline: 15 February 2023)
- Metastatic Melanoma: From Gene Profiling to Targeted Therapy (Deadline: 20 February 2023)
- Targeting Tumor Cell-Intrinsic Checkpoint Molecules: Beyond the Control of Anti-tumor Immunity (Deadline: 20 February 2023)
- Influence of Insulins, IGFs, Their Receptors and PI3-Kinase/Akt Pathway Activation on Cancer Development, Progression, and Resistance to Therapy (Deadline: 28 February 2023)
- The Expressions, Targets, Mechanisms of Action and Functions of RNAs in Brain Tumor (Deadline: 1 March 2023)
- New Perspectives of Renal Cell Cancer (Deadline: 10 March 2023)
- Immune and Genetic Landscape of Lymph Nodes in Cancer (Deadline: 31 March 2023)
- Clonal Evolution in Cancer (Deadline: 31 March 2023)
- Advances in Molecular Mechanisms of Gastrointestinal Tumors (Deadline: 15 April 2023)
- Molecular Biology of Colorectal Cancers (Deadline: 15 May 2023)
- From Chronic Disorders toward Carcinogenesis: Molecular Mechanisms and Potential Therapeutic Approaches (Deadline: 31 May 2023)
- Growth Factors and Receptor Tyrosine Kinases in Development, Regeneration, and Tumorigenesis (Deadline: 1 June 2023)
- Rare Gynecological Cancers (Deadline: 30 June 2023)
- Advances in Cancer Glycobiology (Deadline: 15 August 2023)
- Cancers Driven by HIF (Deadline: 20 October 2023)
Topical Collections
Following topical collections within this section are currently open for submissions:
- DNA Damage in Cancer
- Frontiers in Head and Neck Cancer Biology and Clinical Management
- Incorporating DNA Damage Response (DDR) Mechanisms in Cancer Systems
- Novel Biomarkers and Molecular Targets in Cancer
- Prostate Cancer—from Molecular Mechanisms to Clinical Care
- Recent Advances in Tumor Suppressor
- Role of Stromal Cells in Determining Tumor and Cancer Stem Cell Behaviors and Therapeutic Response
- Stemness in Cancer
