White adipose tissue (WAT) and the gut are involved in the development of neuroinflammation when an organism detects any kind of injury, thereby triggering metainflammation. In fact, the autonomous nervous system innervates both tissues, although the...
High-precision cooperative control of dual-arm manipulators faces significant challenges arising from complex dynamic coupling, parametric uncertainties, and external disturbances. Furthermore, in networked control scenarios, communication bandwidth...
A series of side-chain functionalized polytetrahydrofuran (PTHF) derivatives were synthesized via the blue-light photocatalytic thiol-ene “click” reaction. Firstly, unsaturated polytetrahydrofuran (UPTHF) as a new unsaturated polyether wa...
Several varieties of small nucleic acid constructs are able to modulate gene expression via one of a number of different pathways and mechanisms. These constructs can be synthesized, assembled and delivered to cells where they are able to impart regu...
Similar to other cell types, neutrophilic granulocytes also release extracellular vesicles (EVs), mainly medium-sized microvesicles/microparticles. According to published data, authors have reached a consensus on the physical parameters (size, densit...
Traumatic spinal cord injury (SCI) elicits an acute inflammatory response which comprises numerous cell populations. It is driven by the immediate response of macrophages and microglia, which triggers activation of genes responsible for the dysregula...
Plants constantly suffer from simultaneous infection by multiple pathogens, which can be divided into biotrophic, hemibiotrophic, and necrotrophic pathogens, according to their lifestyles. Many studies have contributed to improving our knowledge of h...
Pigment nephropathy is an acute decline in renal function following the deposition of endogenous haem-containing proteins in the kidneys. Haem pigments such as myoglobin and haemoglobin are filtered by glomeruli and absorbed by the proximal tubules....
This paper proposes an event-triggered fault-tolerant time-varying formation control method dedicated to multiple unmanned aerial vehicles (UAVs). We meticulously design a formation-tracking controller with a predefined tracking performance to accomm...
COPD is a leading cause of death worldwide, with acute exacerbations being a major contributor to disease morbidity and mortality. Indeed, exacerbations are associated with loss of lung function, and exacerbation frequency predicts poor prognosis. Re...
The intestinal epithelium serves as an effective barrier against the external environment, hampering the passage of potentially harmful substances (such as pathogenic microbes) that could trigger an exacerbated host immune response. The integrity of...
This study focuses on the cooperative formation control problem of six-degree-of-freedom (6-DOF) fixed-wing unmanned aerial vehicles (UAVs) under constraints of limited communication resources and strict time requirements. The core innovation of the...
The capacity to induce tumour-cell specific apoptosis represents the most unique feature of the TNF receptor (TNFR) family member CD40. Recent studies on the signalling events triggered by its membrane-presented ligand CD40L (mCD40L) in normal and ma...
Background/Objectives: The renin–angiotensin–aldosterone (RAA) system is a key regulator of cardiovascular homeostasis. Recent evidence suggests that Angiotensin II (Ang II) can trigger ferroptosis, an iron-dependent form of cell death. W...
Inflammation is the reaction of the immune system to an injury; it is aimed at the recovery and repair of damaged tissue. The inflammatory response can be beneficial to the animal since it will reestablish tissue homeostasis if well regulated. Howeve...
In this paper, we investigate the problem of a dynamic event-triggered robust controller design for flexible robotic arm systems with continuous-time phase-type semi-Markov jump process. In particular, the change in moment of inertia is first conside...
This paper investigates the state estimation problem for nonlinear cyber–physical systems (CPSs). To conserve system resources, we propose a novel hybrid dynamic event-triggered mechanism (ETM) that prevents the occurrence of Zeno behavior. Thi...
This paper attempts to develop a unified model predictive control (MPC) method for integrated path planning and trajectory tracking of autonomous underwater vehicles (AUVs). To deal with the computational burden of online path planning, an event-trig...
Conventional droop control (a decentralized method to regulate power sharing by adjusting voltage–current slopes) in DC microgrids faces challenges in balancing precise current distribution, bus voltage regulation, and communication pressure, e...
In addition to its function as an intravascular lipid transporter, LDL also triggers signal transduction in endothelial cells (ECs), which, among other things, trigger immunomodulatory cascades, e.g., IL-6 upregulation. However, the molecular mechani...
This paper is concerned with the adaptive event-triggered finite-time pinning synchronization control problem for T-S fuzzy discrete complex networks (TSFDCNs) with time-varying delays. In order to accurately describe discrete dynamical behaviors, we...
Plants are challenged by different microbial pathogens that affect their growth and productivity. However, to defend pathogen attack, plants use diverse immune responses, such as pattern-triggered immunity (PTI), effector-triggered immunity (ETI), RN...
Cyber physical systems (CPSs) increasingly depend on complex hardware IP cores to perform critical functions. However, triggered hardware Trojans’ stealthy, malicious modifications activated under rare conditions pose significant threats to the...
The polybasic juxtamembrane region (5RK) of the plasma membrane neuronal SNARE, syntaxin1A (Syx), was previously shown by us to act as a fusion clamp in PC12 cells, as charge neutralization of 5RK promotes spontaneous and inhibits Ca2+-triggered rele...
In the presented paper, the leader-following consensus algorithm of a multi-agent system (MAS) is used along with the centralized event-triggering scheme to make the speed of the network-coupled multiple-motors synchronizable. In the proposed method,...
This paper presents a novel methodology for assessing islanding microgrids from the economical and functional perspective, for various stakeholders. The paper proposes the triggers for competitive deployment of microgeneration, storage, microgrid isl...
An acyl radical generation and functionalization strategy through direct photoexcitation of benzothiazolines has been developed. The formed acyl radical species can either be trapped by quinoxalin-2-ones to realize their C(3)-H functionalization or t...
The I-κB-Kinase (IKK) complex represents a central signaling nexus in the TNF-dependent activation of the pro-inflammatory NF-κB pathway. However, recent studies suggested that the distinct IKK subunits (IKKα, IKKβ, and NEMO) m...
The initial step of retrovirus entry—the interaction between the virus envelope glycoprotein trimer and a cellular receptor—is complex, involving multiple, noncontiguous determinants in both proteins that specify receptor choice, binding...
The pancreatic beta cell is a highly specialized cell type whose primary function is to secrete insulin in response to nutrients to maintain glucose homeostasis in the body. As such, the beta cell has developed unique metabolic characteristics to ach...
P53 is known as the most critical tumor suppressor and is often referred to as the guardian of our genome. More than 40 years after its discovery, we are still struggling to understand all molecular details on how this transcription factor prevents o...
In the semi-arid Texas High Plains, the underlying Ogallala Aquifer is experiencing continuing decline due to long-term pumping for irrigation with limited recharge. Accurate simulation of irrigation and other associated water balance components are...
Baby Boom (BBM) is a key transcription factor that triggers embryogenesis, enhances transformation and regeneration efficiencies, and regulates developmental pathways in plants. Triggering or activating BBM in non-model crops could overcome the bottl...
Inflammatory mediators trigger polymorphonuclear neutrophils (PMN) to produce reactive oxygen species (ROS: O2-, H2O2, ∙OH). Mediated by myeloperoxidase in PMN, HOCl is formed, detectable in a chemiluminescence (CL) assay. We have shown that the abun...
Stimuli-responsive drug-delivery systems (SRDDS) have transformed precision medicine by enabling spatiotemporal control over therapeutic release, significantly reducing off-target toxicity while enhancing efficacy at the disease site. Naturally occur...
Coronavirus disease 2019 (COVID-19) can lead to various multisystem disorders, including thrombotic microangiopathy (TMA). We present here eight patients with COVID-19-associated TMA who were treated at our center. Our aim was to summarize the demogr...
In the framework of the Einstein–Dirac-aether theory we consider a phenomenological model of the spontaneous growth of the fermion number, which is triggered by the dynamic aether. The trigger version of spinorization of the early Universe is a...
This paper presents a new approach to integral sliding mode control for discrete nonlinear systems with time delay. The approach is based on an event-triggered scheme and is applied to Takagi–Sugeno fuzzy models. In the first step, a new integr...
This article discusses the event-triggered consensus problem for a switched multi-agent system (MASs) with switching topologies. An observer-based dynamic event-triggered (DET) controller with a discontinuous nonlinear term is designed to reduce ardu...
Privacy-preserving has been crucial technique of multi-UAV systems, including cooperative detection, cooperative penetration and strike. Unprocessed interactive information poses a serious privacy threat to UAV swarm collaborative tasks. Considering...
Hybrid power systems based on renewable energy sources and diesel generators are efficient solutions for supplying electricity to remote and off-grid locations. One of the most crucial problems in hybrid power systems is frequency regulation, which i...
Histones are cationic nuclear proteins that are essential for the structure and functions of eukaryotic chromatin. However, extracellular histones trigger inflammatory responses and contribute to death in sepsis by unknown mechanisms. We recently rep...
High levels of reactive oxygen species (ROS) can lead to impairment of cell structure, biomolecules’ loss of function and cell death and are associated with liver diseases. Cells that survive increased ROS often undergo malignant transformation...
We previously reported the novel finding that β3-AR is functionally expressed in the renal tubule and shares its cellular localization with the vasopressin receptor AVPR2, whose physiological stimulation triggers antidiuresis by increasing the p...
This paper investigates the optimal tracking control problem for a Mecanum-wheeled mobile robot subject to asymmetric actuator saturation. Within the command-filtered backstepping framework, a switching event-triggered control strategy based on reinf...
Autonomous Underwater Vehicle (AUV) swarms possess advantages such as efficiency, reliability, flexibility, and extensive coverage in underwater operations. However, their coordinated control is challenged by communication interruptions and actuator...
Under the joint influence of climate change and human production and living activities on land and sea, the morphology and use function of the coastline have undergone notable changes, triggering more significant environmental and ecological effects....
A method for the synthesis of C4-benzhydryl-functionalized 3,4-dihydropyridin-2-ones using complementary addition of benzhydryllithium and/or benzhydrylmagnesiate reagents to 2-pyridones, with high regioselectivity triggered by substituents, is descr...
Enterovirus 2Apro is a protease that proteolytically processes the viral polyprotein and cleaves several host proteins to antagonize host responses during enteroviral infection. Recently, the host protein actin histidine methyltransferase SET domain...
Retinal neurodegeneration, an early characteristic of several blinding diseases, triggers glial activation, resulting in inflammation, secondary damage and visual impairment. Treatments that aim only at neuroprotection have failed clinically. Here, w...
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