Special Issue "Gut Health in Poultry Production"

A special issue of Microorganisms (ISSN 2076-2607). This special issue belongs to the section "Gut Microbiota".

Deadline for manuscript submissions: 30 June 2019

Special Issue Editor

Guest Editor
Dr. Michael H. Kogut

USDA-ARS, Southern Plains Agricultural Research Center, 2881 F&B Road, College Station, TX 77845, USA
Website | E-Mail
Phone: 979-260-3772
Interests: poultry, foodborne pathogens, gut health, gut microbiota, infection and immune, food and feed safety, alternatives to antibiotics

Special Issue Information

Dear Colleagues,

Optimal gut health is of vital importance to the performance of poultry. There is a direct relationship between bird performance and a “healthy” gastrointestinal tract (GIT), with the GIT responsible for regulating physiological homeostasis that provides an animal with the ability to withstand infectious and non-infectious stressors. Gut health encompasses a number of physiological and functional features, including nutrient digestion and absorption, host metabolism and energy generation, a stable microbiome, mucus layer development, barrier function, and mucosal immune responses, all of which are required to interact so that a bird is able to perform its physiological functions and perform as close as possible to 100% of its genetic potential. The comprehension of gut health requires the elucidation of the interactions between all of these components. Understanding the interactions between these diverse physiological features emphasizes the extent of areas encompassed by gut health and the ability to regulate poultry production. Furthermore, worldwide public concerns about poultry production’s dependency on the use of growth-promoting antibiotics (AGPs) have resulted in the ban of AGPs by the European Union and a dramatic reassessment of their use in the United States. Thus, a great deal of current research is focused on the development of alternatives to antibiotics for sustainable poultry production.  Thus, understanding gut health has been a primary focus of the poultry industry worldwide as a means of increasing production of meat and eggs, reducing the use of antibiotics, and enhancing animal welfare. The poultry industry has been at the forefront of advances in the development of pre- and probiotics, nutritional antioxidants, essential oils, anti-nutritional enzymes, and immune modulators for the regulation of gut health and functionality. This Special Issue will focus on the impact of a healthy gut on poultry health, pathology, diseases, physiology, and production. All studies that will help demonstrate the regulation and/or dysregulation of gut health in poultry by infectious and non-infectious stressors are welcome.

Dr. Michael H. Kogut
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All papers will be peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Microorganisms is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 1000 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.


  • microbiota
  • chickens
  • probiotics
  • prebiotics
  • mucosal immunity
  • alternatives to antibiotics

Published Papers (1 paper)

View options order results:
result details:
Displaying articles 1-1
Export citation of selected articles as:


Open AccessArticle Bacillus subtilis DSM 32315 Supplementation Attenuates the Effects of Clostridium perfringens Challenge on the Growth Performance and Intestinal Microbiota of Broiler Chickens
Microorganisms 2019, 7(3), 71; https://doi.org/10.3390/microorganisms7030071
Received: 6 February 2019 / Revised: 23 February 2019 / Accepted: 4 March 2019 / Published: 5 March 2019
PDF Full-text (1277 KB) | HTML Full-text | XML Full-text
The objective of this study was to evaluate the effects of the dietary supplementation of Bacillus subtilis DSM 32315 (probiotic) on the performance and intestinal microbiota of broiler chickens infected with Clostridium perfringens (CP). One-day-old broiler chickens were assigned to 3 treatments with [...] Read more.
The objective of this study was to evaluate the effects of the dietary supplementation of Bacillus subtilis DSM 32315 (probiotic) on the performance and intestinal microbiota of broiler chickens infected with Clostridium perfringens (CP). One-day-old broiler chickens were assigned to 3 treatments with 8 replicate pens (50 birds/pen). The treatments were: non-infected control; infected control; and infected supplemented with probiotic (1 × 106 CFU/g of feed). On day of hatch, all birds were sprayed with a coccidia vaccine based on the manufacturer recommended dosage. On d 18–20 the infected birds were inoculated with CP via feed. Necrotic enteritis (NE) lesion score was performed on d 21. Digestive tract of 2 birds/pen was collected on d 21 to analyze the ileal and cecal microbiota by 16S rRNA sequencing. Performance was evaluated on d 28 and 42. On d 21, probiotic supplementation reduced (p < 0.001) the severity of NE related lesion versus infected control birds. On d 28, feed efficiency was improved (p < 0.001) in birds supplemented with probiotic versus infected control birds. On d 42, body weight gain (BW gain) and feed conversion ratio (FCR) were improved (p < 0.001) in probiotic supplemented birds versus infected control birds. The diversity, composition and predictive function of the intestinal microbial digesta changed with the infection but the supplementation of probiotic reduced these variations. Therefore, dietary supplementation of Bacillus subtilis DSM 32315 was beneficial in attenuating the negative effects of CP challenge on the performance and intestinal microbiota of broilers chickens. Full article
(This article belongs to the Special Issue Gut Health in Poultry Production)

Figure 1

Microorganisms EISSN 2076-2607 Published by MDPI AG, Basel, Switzerland RSS E-Mail Table of Contents Alert
Back to Top