Announcements

MDPI is delighted to announce the establishment of the Michele Parrinello Award. Named in honor of Professor Michele Parrinello, the award celebrates his exceptional contributions and his profound impact on the field of computational physical science research.

The award will be presented biennially to distinguished scientists who have made outstanding achievements and contributions in the field of computational physical science—spanning physics, chemistry, and materials science.

About Professor Michele Parrinello

"Do not be afraid of new things. I see it many times when we discuss a new thing that young people are scared to go against the mainstream a little bit, thinking what is going to happen to me and so on. Be confident that what you do is meaningful, and do not be afraid, do not listen too much to what other people have to say.”

——Professor Michele Parrinello

Born in Messina in 1945, he received his degree from the University of Bologna and is currently affiliated with the Italian Institute of Technology. Professor Parrinello is known for his many technical innovations in the field of atomistic simulations and for a wealth of interdisciplinary applications ranging from materials science to chemistry and biology. Together with Roberto Car, he introduced ab initio molecular dynamics, also known as the Car–Parrinello method, marking the beginning of a new era both in the area of electronic structure calculations and in molecular dynamics simulations. He is also known for the Parrinello–Rahman method, which allows crystalline phase transitions to be studied by molecular dynamics. More recently, he has introduced metadynamics for the study of rare events and the calculation of free energies.

For his work, he has been awarded many prizes and honorary degrees. He is a member of numerous academies and learned societies, including the German Berlin-Brandenburgische Akademie der Wissenschaften, the British Royal Society, and the Italian Accademia Nazionale dei Lincei, which is the major academy in his home country of Italy.

Award Committee

The award committee will be chaired by Professor Xin-Gao Gong, a computational condensed matter physicist, academician of the Chinese Academy of Sciences, and professor at the Department of Physics, Fudan University. Professor Xin-Gao Gong will lead a panel of several senior experts in the field to oversee the evaluation and selection process. The Institute for Computational Physical Sciences at Fudan University (Shanghai, China), led by Professor Xin-Gao Gong, will serve as the supporting institute for the award.

"We hope the Michele Parrinello Award will recognize scientists who have made significant contributions to the field of computational condensed matter physics and at the same time set a benchmark for the younger generation, providing clear direction for their pursuit—this is precisely the original intention behind establishing the award."

——Professor Xin-Gao Gong

The first edition of the award was officially launched on 1 November 2025. Nominations will be accepted before the end of March 2026. For further details, please visit mparrinelloaward.org.

About the MDPI Sustainability Foundation and MDPI Awards

The Michele Parrinello Award is part of the MDPI Sustainability Foundation, which is dedicated to advancing sustainable development through scientific progress and global collaboration. The foundation also oversees the World Sustainability Award, the Emerging Sustainability Leader Award, and the Tu Youyou Award. The establishment of the Michele Parrinello Award will further enrich the existing award portfolio, providing continued and diversified financial support to outstanding professionals across various fields. 

In addition to these foundation-level awards, MDPI journals also recognize outstanding contributions through a range of honors, including Best Paper Awards, Outstanding Reviewer Awards, Young Investigator Awards, Travel Awards, Best PhD Thesis Awards, Editor of Distinction Awards, and others. These initiatives aim to recognize excellence across disciplines and career stages, contributing to the long-term vitality and sustainability of scientific research.

Find more information on awards here.

We are honored to recognize the 2024 MDPI Top 1000 Reviewers—scholars whose exemplary commitment to rigorous and constructive peer review is vital in upholding the highest standards of academic publishing.

Selected from a distinguished pool of 215,000 reviewers from 65 countries and regions worldwide, these honorees stand out for their exceptional expertise, diligence, and dedication to advancing research through timely and thoughtful reviews. Their constructive and impartial feedback ensures the publication of high-quality, impactful research, while their timely reviews facilitate swift revisions and faster publication of innovative work.

Peer review is the invisible foundation of academic progress. With gratitude and respect, we celebrate these 1000 scholars who made that foundation stronger in 2024. We respected all privacy preferences, with part of nominees opting for limited attribution.

The names of these reviewers are listed below in alphabetical order by first name:

Journal of Clinical Medicine (JCM, ISSN: 2077-0383) is an open access journal and all of its publications are freely available for reading and download. To quickly attract readers to the key points of your research, it is particularly important to visualize the research. JCM supports two ways to do this: video abstracts and graphical abstracts. They can be added at the same time, and video abstracts can be uploaded at any time.

Video abstracts offer a dynamic and engaging way to present the content of submissions. They can provide a more in-depth and accessible explanation of research, increasing its reach for a wider audience. Here are the requirements for video abstracts:

• File formats—mp4, webm, ogv (mp4 format is usually recommended);
• File size—no more than 200 MB;
• Video length—no more than 5 minutes.

Video abstracts not only contribute to increasing the visibility of papers but also enhance the overall impact of research. We look forward to reading submitted papers with video abstracts.

Graphical abstracts are also commonly used. They play a significant role in the rapid dissemination of academic research through concise visual expression and a richly illustrated presentation. Here are some details to keep in mind when creating a graphical abstract:

• It should not be exactly the same as any figure in the body of the paper, a simple superposition of several subfigures, or a combination of the text abstract and a picture;
• It should be a piece of original and unpublished artwork. Any postage stamps, currency from any country, or trademarked items should not be included in it. No copyrighted material should be used;
• It should be a high-quality illustration or diagram in any of the following file formats: PNG, JPEG, or TIFF. minimum required size for the graphical abstract is 560 × 1100 pixels (height × width);
• It is recommended to use fonts such as Times, Arial, Courier, Helvetica, Ubuntu, and Calibri;
• Please use symbols correctly, and do not use commas instead of decimal points in numbers;
• Avoid large blocks of text or large blank spaces in the image;
• Do not include “Graphical Abstract” as a heading in the image.

Video abstracts and graphical abstracts can be submitted together with the main manuscript in Step 1: “Submission Details” of the manuscript submission system. Should you require additional time to prepare the video abstract or graphical abstract after submitting the main manuscript, please promptly contact the JCM Editorial Office via email (jcm@mdpi.com) for coordination. If you intend to supplement and submit the aforementioned abstracts after the manuscript is accepted, we recommend proactively communicating with the Editorial Office.

Dr. Jennifer Fumanelli is a young pediatric cardiologist and arrhythmologist with an interest in cardiac resynchronization therapy for patients with pediatric and congenital heart disease. She is currently pursuing a post-doc fellowship in Prague, focusing on this topic and conducting further investigations in arrhythmological and cardiological fields. In the near future, she will be spending time in Rotterdam for the Electrophysiology (EP) Fellowship.

She is a member of several national and international societies such as the European Society of Cardiology (ESC), European Heart Rhythm Association (EHRA), and Association for European Paediatric and Congenital Cardiology (AEPC), and she has taken part in many congresses and published several papers as the first author and co-author. We offer our congratulations to Dr. Jennifer Fumanelli as the winner of the JCM 2024 Best PhD Thesis Award.

The following is a short interview with Dr. Jennifer Fumanelli:

1. Could you briefly introduce yourself and the core focus of your PhD research?
   Thank you all for this award. I am truly honored and grateful to be given this opportunity to share my PhD research with the broader scientific community, especially on a topic as specialized as pediatric cardiology.
   I am a pediatric cardiologist, originally trained in Padova, Italy, where I completed most of my academic and clinical education. For the past year, I have been based in Prague, where I continue to pursue my primary research interest: pediatric arrhythmology.
   My PhD work specifically focused on device therapy in children—particularly the use of implantable defibrillators in young patients. It has been a deeply meaningful project, and I am very happy to have had the chance to present some of our key findings here today.
2. What was the most significant challenge you faced during your PhD research, and how did you overcome it while maintaining your motivation?
   The most significant challenge during my three years of PhD research was undoubtedly obtaining an adequate sample size. The pediatric studies—especially in subspecialties like arrhythmology—involve a much smaller patient population compared to adult studies, and so building a robust single-center dataset was difficult.
   My PhD thesis covered several purposes: the definition of the type of pediatric population requiring defibrillator implantation (like the primary electrical disease, cardiomyopathies and congenital heart disease) focusing on a subgroup of patients like the patients affected by HCM (hypertrophic cardiomyopathy).
   In this latter subgroup, the sample size remained very small, which limited our ability to draw statistically significant conclusions. Despite this, I believe the absolute data we gathered still provide meaningful clinical insights and valuable information for the scientific community.
3. Looking forward, and from the unique perspective your research has provided, what broader trends or emerging areas do you believe will be critical for advancing clinical medicine in the next decade?
   From my research experience in pediatric cardiology—particularly in arrhythmology—I believe one of the most critical areas for advancement in the coming decade will be the development of device technology specifically designed for children.
   Currently, we often rely on devices and technologies originally developed for adults, adapting them as best we can through customized programming and implantation techniques. While this is practical, it is not ideal. There is a clear need for more personalized, pediatric-specific technologies that account for children’s unique physiological and developmental characteristics.
   Beyond devices, I also see great potential in preclinical research aimed at discovering new antiarrhythmic drugs—especially those that can be administered via parenteral routes. The current arsenal of medications suitable for acute arrhythmia management in children remains limited. Developing new, safe, and effective antiarrhythmic agents would significantly enhance our ability to respond to emergent situations in young patients.
   These two directions—tailored device technology and novel drug development—will, in my view, substantially elevate the safety, efficacy, and personalization of care in pediatric arrhythmology over the next ten years.
4. What role does AI technology currently play in your research field, and what do you see as its most exciting future opportunities and challenges?
   The artificial intelligence technology is really a nice emergency tool, which now is basically used for every topic of medicine. Regarding pediatric cardiology, the improvement of the 3D-echo is a concrete example of this application, which has positive effects like a tailored surgical plan. Besides, the use of non-radioscopic mapping systems for electrophysiological studies represents another application. I hope there will be further developments on the technology of these types of electroanatomical mapping systems, which help physicians to better define the anatomy and the relative arrhythmic diagnosis and therapy without delivering X-rays.
5. What prompted you to apply for the JCM Best PhD Thesis Award, and what has been your experience with our journal? How does it feel to receive this recognition for your work?
   I decided to apply for the JCM Best PhD Thesis Award because I truly wanted to share the results of my PhD research. My work focuses on a highly specialized area—pediatric arrhythmology—which involves many unique aspects and challenges. My primary goal was to present these findings to the broader scientific community through a respected platform.
   My connection with the Journal of Clinical Medicine (JCM) goes back several years. I have previously published papers in JCM as both first author and co-author, and this positive experience motivated me to submit my thesis for consideration here as well.
   Receiving this award is truly encouraging. It inspires me to continue advancing in this field, and I am already actively involved in new research projects—basically all centered on arrhythmology. I look forward to the possibility of sharing these future results with JCM as well.
6. Who has been your most important mentor during your PhD, and how did they influence you?
   Rather than having one single mentor, I feel deeply grateful to all the doctors and professors I've had the chance to learn from—both in Italy and during my research time abroad. Each of them, in different ways, encouraged me to grow and pushed me to do my best throughout my PhD journey.
   These collective interactions and guidance have shaped my development, and I consider this shared mentorship a truly positive and invaluable part of my experience.
7. JCM is an Open Access (OA) journal. As an award-winning researcher, what is your perspective on the Open Access publishing model? What advantages or challenges do you see it presenting for scientists like yourself?
   I believe Open Access is a very positive development for researchers. It makes scientific work far more accessible to the entire research community, allowing us to find and engage with relevant articles more easily. This is especially helpful when addressing specific clinical questions or seeking new ideas in our field.
   While every publishing model has its challenges, I see significantly more advantages in OA—particularly in how it supports the sharing and impact of knowledge.
8. Beyond publishing, MDPI is committed to supporting the academic community through various initiatives. We are planning the Academic Publishing Workshop. Could you please indicate which of the following topics you would be most interested in?
        1. Academic article writing techniques.
        2. Benefits of the Open Access publishing model, emphasizing its significance in Europe from MDPI’s perspective.
        3. Overview of MDPI’s history, including our journals and services.
        4. MDPI Peer Review Guidelines.
   Certainly. I would be more interested in the first option you mentioned—the one focusing on academic article writing techniques. As an early-career researcher, I believe such guidance would be extremely helpful. Having clear, actionable points to apply during the drafting process would undoubtedly support me in writing stronger and more effective papers.

Finally, we would like to extend our gratitude to Dr. Jennifer Fumanelli and all the distinguished scholars for their significant contributions and support. Your achievements and insights are an inspiration to the community. We welcome you to stay connected for future updates on our awards and academic initiatives. https://www.mdpi.com/journal/jcm/awards.

In support of World Antimicrobial Resistance (AMR) Awareness Week 2025, MDPI is delighted to invite you to our special webinar, “MDPI World AMR Awareness Week Webinar 2025”. This year’s theme, “Act Now: Protect Our Present, Secure Our Future”, serves as a powerful call to immediate action against one of the most pressing global health threats—antimicrobial resistance.

Through this webinar, we aim to highlight the latest research, innovations, and cross-sector collaborations addressing AMR. We hope these discussions will inspire collective action to promote the prudent use of antimicrobials, strengthen prevention and surveillance systems, and accelerate global efforts to safeguard human, animal, and environmental health.

Thank you for joining us as we raise awareness, exchange insights, and reaffirm our shared commitment to a healthier, more resilient future.

keywords: antimicrobial resistance; antifungal resistance; food chain contamination; biofilm infections; nanomedicine; microbial genetics; mycology; public health

Date: 21 November 2025
Time: 9:00 a.m. CET | 4:00 p.m. CST (Asia)
Webinar ID: 883 6849 1341
Webinar Secretariat: journal.webinar@mdpi.com

Register now for free!

Program:

After registering, you will receive a confirmation email on how to join the webinar. Registrations with academic institutional email addresses will be prioritized.

Unable to attend? Register anyway, and we will let you know when the recording is available for viewing.

Webinar Speakers:

• Dr. José Cobo-Díaz, Department of Food Hygiene and Technology, University of Leon, Spain;
• Dr. Ana Alastruey-Izquierdo, National Microbiology Center, Carlos III Health Institute, Spain;
• Dr.  Anam Ahsan, Clinical & Health Sciences / Centre for Pharmaceutical Innovation, University of South Australia, Australia;
• Prof. Dr. Michaela Lackner, Medical University of Innsbruck (MUI), Institute of Hygiene and Medical Microbiology (HMM), Austria;
• Dr.  Elena Perrin, Department of Biology, University of Florence, Italy.

World AMR Awareness Day 2025 draws attention to the urgent global challenge of antimicrobial resistance (AMR)—one of the greatest threats to public health, food security, and sustainable development. This year’s theme, “Act Now: Protect Our Present, Secure Our Future”, calls on the international community to take immediate, coordinated, and sustained action to preserve the effectiveness of life-saving antimicrobials. AMR affects every region of the world and every aspect of modern medicine, from surgery and cancer therapy to animal health and agriculture. Without effective antibiotics, common infections and minor injuries could once again become deadly.

To address this growing crisis, selected MDPI journals provide leading platforms for advancing research on antimicrobial resistance, surveillance, stewardship, and innovative therapeutic strategies. These include studies on new antibiotics, resistance mechanisms, diagnostic tools, infection control, and global policy frameworks. Through curated articles, Special Issues, and reprints, these journals foster cross-disciplinary collaboration among researchers, clinicians, and policymakers to combat AMR through innovation, education, and evidence-based practice.

World AMR Awareness Day serves as a powerful reminder that tackling antimicrobial resistance requires shared responsibility, sustained investment in research and innovation, and collective global action to secure a healthier, more resilient future for all.

“Antibacterial, Antifungal, Antiviral Activity, and Mechanisms of Action of Plant Polyphenols”
by Slavena Davidova, Angel S. Galabov and Galina Satchanska
Microorganisms 2024, 12(12), 2502; https://doi.org/10.3390/microorganisms12122502 

”An Overview of the Recent Advances in Antimicrobial Resistance”
by Manuela Oliveira, Wilson Antunes, Salete Mota, Áurea Madureira-Carvalho, Ricardo Jorge Dinis-Oliveira and Diana Dias da Silva
Microorganisms 2024, 12(9), 1920; https://doi.org/10.3390/microorganisms12091920

“A Mini-Review of In Vitro Data for Candida Species, Including C. auris, Isolated during Clinical Trials of Three New Antifungals: Fosmanogepix, Ibrexafungerp, and Rezafunesgin”
by Ana Espinel-Ingroff and Nathan P. Wiederhold
J. Fungi 2024, 10(5), 362; https://doi.org/10.3390/jof10050362

“ESKAPE: Navigating the Global Battlefield for Antimicrobial Resistance and Defense in Hospitals”
by Kamna Ravi and Baljit Singh
Bacteria 2024, 3(2), 76-98; https://doi.org/10.3390/bacteria3020006

Special Issues:

“A Six-Step Protocol for Monitoring Antimicrobial Resistance Trends Using WHONET and R: Real-World Application and R Code Integration”
by Fabio Ingravalle, Antonio Vinci, Marco Ciotti, Carla Fontana, Francesca Pica, Emanuele Sebastiani, Clara Donnoli, Martino Guido Rizzo, Dario Tedesco, Silvia D’Arezzo et al.
Methods Protoc. 2025, 8(5), 115; https://doi.org/10.3390/mps8050115 

“Improved Prognostic Accuracy of NEWS2 Score with Triage Data in Adults with Bacterial Sepsis: A Retrospective Cohort Study”
by Pietro Pozzessere, Roberto Lovero, Corrado Crocetta, Najada Firza, Vincenzo Brescia, Angela Pia Cazzolla, Mario Dioguardi, Francesco Testa, Marica Colella and Luigi Santacroce
Int. J. Transl. Med. 2025, 5(4), 44; https://doi.org/10.3390/ijtm5040044

“Prevalence and Antimicrobial Resistance of Typhoid Fever in Ghana: A Systematic Review and Meta-Analysis”
by Frederick Kungu, Aaron Awere-Duodu and Eric S. Donkor
Diseases 2025, 13(4), 113; https://doi.org/10.3390/diseases13040113

“Antimicrobial Resistance Patterns and Biofilm Analysis via Sonication in Intensive Care Unit Patients at a County Emergency Hospital in Romania”
by Ioana Roxana Codru, Bogdan Ioan Vintilă, Alina Simona Bereanu, Mihai Sava, Livia Mirela Popa and Victoria Birlutiu
Pharmaceuticals 2025, 18(2), 161; https://doi.org/10.3390/ph18020161 

Special Issues:

“Antimicrobial and Anti-Inflammatory Potentials of Silver Tungstate Nanoparticles, Cytotoxicity and Interference on the Activity of Antimicrobial Drugs”
by Washington de Souza Leal, Juliane Zacour Marinho, Isabela Penna Ceravolo, Lucas Leão Nascimento, Antonio Otávio de Toledo Patrocínio and Marcus Vinícius Dias-Souza
Drugs Drug Candidates 2025, 4(3), 30; https://doi.org/10.3390/ddc4030030

“Release Profile and Antibacterial Activity of Thymus sibthorpii Essential Oil-Incorporated, Optimally Stabilized Type I Collagen Hydrogels”
by Caglar Ersanli, Ioannis Skoufos, Konstantina Fotou, Athina Tzora, Yves Bayon, Despoina Mari, Eleftheria Sarafi, Konstantina Nikolaou and Dimitrios I. Zeugolis
Bioengineering 2025, 12(1), 89; https://doi.org/10.3390/bioengineering12010089

“Antimicrobial Peptides from Frogs of the Glandirana Genus”
by Frederick Harris, David A. Phoenix and Sarah R. Dennison
Biologics 2024, 4(4), 444-507; https://doi.org/10.3390/biologics4040027

“Phytochemical Composition and Antimicrobial and Antibiofilm Effect of Myrciaria cauliflora Hydroethanolic Extract against Staphylococcus aureus and Acinetobacter baumannii”
by Luciane Dias de Oliveira, Ana Luisa Monteiro Ribeiro, Sthéfani de Oliveira Dias, Geovani Moreira da Cruz, Raquel Teles de Menezes, Lara Steffany de Carvalho, Mariana Gadelho Gimenez Diamantino, Thaís Cristine Pereira, Maria Cristina Marcucci and Amjad Abu Hasna
Methods Protoc. 2024, 7(4), 60; https://doi.org/10.3390/mps7040060

“LL-37: Structures, Antimicrobial Activity, and Influence on Amyloid-Related Diseases”
by Surajit Bhattacharjya, Zhizhuo Zhang and Ayyalusamy Ramamoorthy
Biomolecules 2024, 14(3), 320; https://doi.org/10.3390/biom14030320

Special Issues:

“Antimicrobial Resistance Gene Patterns in Traditional Montenegrin Njeguški Cheese Revealed by qPCR”
by Vesna Milanović, Giorgia Rampanti, Andrea Cantarini, Federica Cardinali, Giuseppe Paderni, Aleksandra Martinovic, Andrea Brenciani, Lucia Aquilanti, Andrea Osimani and Cristiana Garofalo
Genes 2025, 16(9), 1089; https://doi.org/10.3390/genes16091089

“Immunotherapy Potential of Animal-Sourced Probiotic Bacteria”
by Isaac Oluseun Adejumo
Biologics 2025, 5(3), 17; https://doi.org/10.3390/biologics5030017

“Screening and Genomic Profiling of Antimicrobial Bacteria Sourced from Poultry Slaughterhouse Effluents: Bacteriocin Production and Safety Evaluation”
by Nuria Peña, Irene Lafuente, Ester Sevillano, Javier Feito, Diogo Contente, Estefanía Muñoz-Atienza, Luis M. Cintas, Pablo E. Hernández and Juan Borrero
Genes 2024, 15(12), 1564; https://doi.org/10.3390/genes15121564 

“The Impact of Antibiotics and Steroids on the Nasal Microbiome in Patients with Chronic Rhinosinusitis: A Systematic Review According to PICO Criteria”
by Antonella Loperfido, Carlo Cavaliere, Elona Begvarfaj, Andrea Ciofalo, Giovanni D’Erme, Marco De Vincentiis, Antonio Greco, Stefano Millarelli, Gianluca Bellocchi and Simonetta Masieri
J. Pers. Med. 2023, 13(11), 1583; https://doi.org/10.3390/jpm13111583

Special Issues:

Med. Sci. Forum, 2025, ECA 2025 The 4th International Electronic Conference on Antibiotics Organiser: MDPI and Antibiotics Volume Editors: Manuel Simões and Marc Maresca Highlights Fourier Transform Infrared Spectroscopy-Based Detection of Amoxicillin and Ampicillin for Advancing Antibiotic Monitoring with Optical Techniques by Vinicius Pereira Anjos et al. Third-Generation Cephalosporin-Resistant Escherichia coli Isolates Belonging to High-Risk Clones Obtained from Fresh Pork Meat in La Plata City, Argentina by Hernán D. Nievas et al. Click here to read the full list of papers.

World Children’s Day was first established in 1954 as Universal Children’s Day and is celebrated on 20 November each year to promote international togetherness and awareness among children worldwide and improve children’s welfare. 20 November 1959 is an important date as it is when the UN General Assembly adopted the Declaration of the Rights of the Child. Additionally, on the same date in 1989, the UN General Assembly adopted the Convention on the Rights of the Child.

From the moment the sun rises, children wake up to a world shaped by choices they did not make. However, every child, everywhere, also wakes up with rights, including the right to be protected, to learn, and to have their voice heard. It is time to listen to children to understand what their lives are like and how their rights are present, missing, or pursued every day.

To commemorate this day, we invite you to explore a curation of insightful articles, journals, and Special Issues across various fields, including pediatric public health, childhood education, child psychology, and child development. By sharing these findings, we hope to advocate, promote, and celebrate children’s rights, and translate these findings into dialogues and actions that will build a better world for children.

Keynote speakers:

Dr. Amy Pan, Medical College of Wisconsin, USA	Prof. David Tzuriel Emeritus, Bar-Ilan University, Israel

Feel free to register for this webinar here!

We are honored to feature a series of insightful interviews with distinguished scholars dedicated to child-centered research, as they share their inspiring journeys and valuable perspectives on advancing children’s well-being, rights, and development in diverse global contexts.

	Name: Dr. Anna Di Sessa Affiliation: University of Campania “Luigi Vanvitelli”, Italy “World Children’s Day serves as a crucial reminder of our collective responsibility to safeguard and prioritize the health, rights, and well-being of children. As a researcher, it underscores the need to address the unique health challenges children face through evidence-based research. On a broader scale, it emphasizes the importance of creating a world where all children can thrive, free from poverty, violence, and neglect”. Please read the full interview here.
	Name: Dr. Diego Gomez-Baya Affiliation: University of Huelva, Spain “Programs to foster positive youth development should be active and participatory, allowing adolescents to take ownership of their own development. Likewise, measures that encourage greater civic and environmental engagement are equally necessary, hand in hand with the promotion of personal character strengths”. Please read the full interview here.
	Name: Dr. Graham Connelly Affiliation: University of Strathclyde, UK “We need to protect children from being harmed by conflict and provide the best care for children affected by strife, dislocation, famine and poverty. We need to fund international children’s agencies better, and yes, of course hold them to account for the funds they receive. There are very good examples, worldwide, of ways of consulting with children that are not tokenistic. I’d like to see these being expanded”. Please read the full interview here.

“Mucous Fistula Refeeding in Newborns: Why, When, How, and Where? Insights from a Systematic Review”
by Layla Musleh, Ilaria Cozzi, Anteo Di Napoli and Fabio Fusaro
Nutrients 2025, 17(15), 2490; https://doi.org/10.3390/nu17152490

“Our Children/Our Future: Examining How Indigenous Peoples in the US Assert Self-Determination and Prioritize Child Wellbeing”
by Meschelle Linjean and Hilary N. Weaver
Genealogy 2025, 9(1), 26; https://doi.org/10.3390/genealogy9010026

“Machine Learning in Pediatric Healthcare: Current Trends, Challenges, and Future Directions”
by Hammad A. Ganatra
J. Clin. Med. 2025, 14(3), 807; https://doi.org/10.3390/jcm14030807

“Developmental Patterns in Autism and Other Neurodevelopmental Disorders in Preschool Children”
by Maria Eugenia Martelli, Federica Gigliotti, Federica Giovannone, Giuliana Lentini, Filippo Manti and Carla Sogos
Children 2025, 12(2), 125; https://doi.org/10.3390/children12020125

“Climate Action and the UNCRC: A ‘Postpaternalist’ World Where Children Claim Their Own Rights”
by Aoife Daly, Nabin Maharjan, Esther Montesinos Calvo-Fernández, Liesl Heila Muller, Emily Margaret Murray, Alicia O’Sullivan, Florencia Paz Landeira and Katie Reid
Youth 2024, 4(4), 1387-1404; https://doi.org/10.3390/youth4040088

“Understanding the Wellbeing Needs of First Nations Children in Out-of-Home Care in Australia: A Comprehensive Literature Review”
by Darren Garvey, Ken Carter, Kate Anderson, Alana Gall, Kirsten Howard, Jemma Venables, Karen Healy, Lea Bill, Angeline Letendre, Michelle Dickson and Gail Garvey
Int. J. Environ. Res. Public Health 2024, 21(9), 1208; https://doi.org/10.3390/ijerph21091208

“A Systematic Review of Economic and Concrete Support to Prevent Child Maltreatment”
by Gretchen Cusick, Jennifer Gaul-Stout, Reiko Kakuyama-Villaber, Olivia Wilks, Yasmin Grewal-Kök
and Clare Anderson
Societies 2024, 14(9), 173; https://doi.org/10.3390/soc14090173

“Family Functioning and Internalizing and Externalizing Problems in Gifted Children”
by Maria Assunta Zanetti, Tommaso Trombetta, Luca Rollè and Carlo Marinoni
Eur. J. Investig. Health Psychol. Educ. 2024, 14(5), 1171-1181; https://doi.org/10.3390/ejihpe14050077

“Impact of Sexual Abuse on Post-Traumatic Stress Disorder in Children and Adolescents: A Systematic Review”
by Ana Carolina Alves, Maria Leitão, Ana Isabel Sani and Diana Moreira
Soc. Sci. 2024, 13(4), 189; https://doi.org/10.3390/socsci13040189

“Challenges of Iron Chelation in Thalassemic Children”
by Alkistis Adramerina and Marina Economou
Thalass. Rep. 2024, 14(1), 1-9; https://doi.org/10.3390/thalassrep14010001

“MIH and Dental Caries in Children: A Systematic Review and Meta-Analysis”
by Marta Mazur, Denise Corridore, Artnora Ndokaj, Roman Ardan, Iole Vozza, Sylvie Babajko and Katia Jedeon
Healthcare 2023, 11(12), 1795; https://doi.org/10.3390/healthcare11121795

“Picture Books, Imagination and Play: Pathways to Positive Reading Identities for Young Children”
by Amanda Niland
Educ. Sci. 2023, 13(5), 511; https://doi.org/10.3390/educsci13050511

“Paying Attention to the Spiritual Flourishing of Young Children in Church Toddler Groups: A Scoping Study Evaluating the Feasibility of a Research Study in This Context”
by Ann Casson, Mary Woolley, Ann Pittaway, Tansy Watts, Nicola Kemp, Robert A. Bowie, Katie Clemmey
and Rosanne Aantjes
Religions 2023, 14(2), 236; https://doi.org/10.3390/rel14020236

“Mitigating the Impact of Maternal Mental Health Challenges on Children’s Development” Guest Editors: Dr. Nanmathi Manian and Prof. Dr. Pamela J. Surkan Submission deadline: 1 January 2026	“Early Childhood Education Policy: Impact on Children’s Well-Being and Development” Guest Editors: Prof. Dr. Nadia Siddiqui and Dr. Johny Daniel Submission deadline: 17 January 2026
“Substance Use and Child Welfare: Intersecting Crises” Guest Editors: Dr. Rebecca Gomez and Dr. Kasey Claborn Submission deadline: 31 January 2026	“Healthy Child, Healthy Adult—Children’s Nutrition and Physical Activity as a Public Health Concern” Guest Editors: Dr. Lindsy Kass and Dr. Gillian McLellan Submission deadline: 28 February 2026
“Shaping Futures: Health Policy Innovations for Neurodevelopmental Disorders in Children” Guest Editor: Dr. Ucheoma Nwaozuru Submission deadline: 15 June 2026	“Parenting in Context: Family Engagement in Promoting Child Development” Guest Editors: Dr. Joo Young Hong and Dr. Shinwoo Choi Submission deadline: 15 September 2026

The endocrine system acts as the body's “command center”, and its dysfunction can lead to a variety of endocrine diseases, which have become a global health challenge. We would like to invite you to read our collection of highly cited papers on endocrine diseases published in Journal of Clinical Medicine (JCM, ISSN: 2077-0383). We hope they provide useful insights for researchers in selecting treatment options and developing health management strategies. Moreover, several hot topic Special Issues pertaining to this topic are currently open for submissions.

1. “The Lipid Accumulation Product Index (LAP) and the Cardiometabolic Index (CMI) Are Useful for Predicting the Presence and Severity of Metabolic Syndrome in Adult Patients with Obesity”
by Sofia Tamini, Adele Bondesan, Diana Caroli and Alessandro Sartorio
J. Clin. Med. 2024, 13(10), 2843; https://doi.org/10.3390/jcm13102843
Full text available online: https://www.mdpi.com/2077-0383/13/10/2843

2. “Pituitary Apoplexy: An Updated Review”
by Pedro Iglesias
J. Clin. Med. 2024, 13(9), 2508; https://doi.org/10.3390/jcm13092508
Full text available online: https://www.mdpi.com/2077-0383/13/9/2508

3. “Complete Blood Count (CBC)-Derived Inflammation Indexes Are Useful in Predicting Metabolic Syndrome in Adults with Severe Obesity”
by Alice Marra, Adele Bondesan, Diana Caroli and Alessandro Sartorio
J. Clin. Med. 2024, 13(5), 1353; https://doi.org/10.3390/jcm13051353
Full text available online: https://www.mdpi.com/2077-0383/13/5/1353

4. “Interactions between the Exocrine and the Endocrine Pancreas”
by Roberto Valente, Alessandro Coppola, Chiara Maria Scandavini, Asif Halimi, Annelie Magnusson, Augusto Lauro, Ira Sotirova, Urban Arnelo and Oskar Franklin
J. Clin. Med. 2024, 13(4), 1179; https://doi.org/10.3390/jcm13041179
Full text available online: https://www.mdpi.com/2077-0383/13/4/1179

5. “Barriers to Type 1 Diabetes Adherence in Adolescents”
by Sarah Azar, Noa Maroun Abou Jaoude, Andrzej Kędzia and Elżbieta Niechciał
J. Clin. Med. 2024, 13(19), 5669; https://doi.org/10.3390/jcm13195669
Full text available online: https://www.mdpi.com/2077-0383/13/19/5669

6. “Pancreatitis Risk Associated with GLP-1 Receptor Agonists, Considered as a Single Class, in a Comorbidity-Free Subgroup of Type 2 Diabetes Patients in the United States: A Propensity Score-Matched Analysis”
by Mark Ayoub, Harleen Chela, Nisar Amin, Roberta Hunter, Javaria Anwar, Veysel Tahan and Ebubekir Daglilar
J. Clin. Med. 2025, 14(3), 944; https://doi.org/10.3390/jcm14030944
Full text available online: https://www.mdpi.com/2077-0383/14/3/944

7. “Challenges of Managing Type 3c Diabetes in the Context of Pancreatic Resection, Cancer and Trauma”
by Colton D. Wayne, Chahrazed Benbetka, Gail E. Besner and Siddharth Narayanan
J. Clin. Med. 2024, 13(10), 2993; https://doi.org/10.3390/jcm13102993
Full text available online: https://www.mdpi.com/2077-0383/13/10/2993

8. “Impact of Concurrent Exercise Training on Cardiac Autonomic Modulation, Metabolic Profile, Body Composition, Cardiorespiratory Fitness, and Quality of Life in Type 2 Diabetes with Cardiac Autonomic Neuropathy: A Randomized Controlled Trial”
by Saima Zaki, Md Farhan Alam, Saurabh Sharma, Said El-Ashker, Mohammad Ahsan and Shibili Nuhmani.
J. Clin. Med. 2024, 13(13), 3910; https://doi.org/10.3390/jcm13133910
Full text available online: https://www.mdpi.com/2077-0383/13/13/3910

9. “Early-Onset Colorectal Cancer: Are Neuroendocrine Tumors or Adenocarcinomas the Culprit? Analysis of the Largest U.S. Cancer Incidence Database, 2001–2020”
by Yazan Abboud, Madison Fraser, Imran Qureshi and Kaveh Hajifathalian
J. Clin. Med. 2024, 13(4), 1098; https://doi.org/10.3390/jcm13041098
Full text available online: https://www.mdpi.com/2077-0383/13/4/1098

10. “Adrenal Cysts: To Operate or Not to Operate?”
by Ivana Bozic Antic, Igor Djurisic and Srdjan Nikolic
J. Clin. Med. 2024, 13(3), 846; https://doi.org/10.3390/jcm13030846
Full text available online: https://www.mdpi.com/2077-0383/13/3/846

Special Issues:
“Chronic Complications of Type 2 Diabetes: Prevalence, Prevention, and Management” Guest Editor: Dr. Ilias Migdalis Submission deadline: 20 January 2026	“Neuroendocrine Tumors: Challenges and Future Perspectives (Second Edition) ” Guest Editors: Dr. Anna La Salvia Dr. Giuseppe Lamberti Submission deadline: 20 February 2026
“New Advances and Clinical Outcomes of Pediatric Endocrinology” Guest Editor: Dr. Gerdi Tuli Submission deadline: 28 February 2026	“Recent Advances in Endocrine Surgery—2nd Edition” Guest Editor: Dr. Gregorio Scerrino Submission deadline: 20 April 2026

World Cervical Cancer Elimination Day is an annual observance aimed at enhancing awareness of cervical cancer prevention and treatment, fostering a deeper recognition of the urgency to eliminate the disease, while also drawing attention to the global health burden it imposes—especially on women’s well-being. This day highlights the pivotal role that collective action plays in advancing cervical cancer screening, vaccination, and access to care, thereby reinforcing the imperative for its elimination. Under the theme “Act Now: Eliminate Cervical Cancer”, calls for bold, united action to build on existing progress and accelerate impact toward the 90-70-90 targets by 2030.

“Progress and Challenges in Canada’s Path Toward the Elimination of Cervical Cancer”
by Samara Perez
Curr. Oncol. 2024, 31(10), 5850-5861; https://doi.org/10.3390/curroncol31100435

“High-Risk HPV Screening Initiative in Kosovo—A Way to Optimize HPV Vaccination for Cervical Cancer”
by Jessica L. Bentz, Rachael E. Barney, Natalia Georgantzoglou, Suzana Manxhuka-Kerliu et al.
Diseases 2024, 12(8), 189; https://doi.org/10.3390/diseases12080189

“Cervical Cancer Genetic Profile through Circulating Tumor DNA: What Can We Learn from Blood?”
by Sevastiani Antonouli, Valentina Di Nisio, Nikoletta Daponte, Athina-Ioanna Daponte and Alexandros Daponte
Biomolecules 2024, 14(7), 825; https://doi.org/10.3390/biom14070825

“An Epidemiological Study of Cervical Cancer Trends among Women with Human Immunodeficiency Virus”
by Arlesia Mathis, Ukamaka D. Smith, Vanessa Crowther, Torhonda Lee and Sandra Suther
Healthcare 2024, 12(12), 1178; https://doi.org/10.3390/healthcare12121178

“Artificial Intelligence and Colposcopy: Automatic Identification of Cervical Squamous Cell Carcinoma Precursors”
by Miguel Mascarenhas, Inês Alencoão, Maria João Carinhas, Miguel Martins, Pedro Cardoso, Francisco Mendes, Joana Fernandes, João Ferreira, Guilherme Macedo and Rosa Zulmira Macedo
J. Clin. Med. 2024, 13(10), 3003; https://doi.org/10.3390/jcm13103003

“Post-Conization HPV Vaccination and Its Impact on Viral Status: A Retrospective Cohort Study in Troms and Finnmark, 2022”
by Marie Rykkelid, Helga Marie Wennberg, Elin Richardsen and Sveinung Wergeland Sørbye
Pathogens 2024, 13(5), 381; https://doi.org/10.3390/pathogens13050381

“Identification and Validation of eRNA as a Prognostic Indicator for Cervical Cancer”
by Lijing Huang, Jingkai Zhang, Zhou Songyang and Yuanyan Xiong
Biology 2024, 13(4), 227; https://doi.org/10.3390/biology13040227

“Cervical Cancer Associated with Pregnancy: Current Challenges and Future Strategies”
by Jennifer Le Guévelou, Lise Selleret, Enora Laas, Fabrice Lecuru and Manon Kissel
Cancers 2024, 16(7), 1341; https://doi.org/10.3390/cancers16071341

“Correlation of the HPV 16 Genotype Persistence in Women Undergoing LEEP for CIN3 with the Risk of CIN2+ Relapses in the First 18 Months of Follow-Up: A Multicenter Retrospective Study”
by Maria Teresa Bruno, Gaetano Valenti, Zaira Ruggeri, Giosuè Giordano Incognito, Paola Coretti, Giuseppe Dario Montana, Marco Marzio Panella and Liliana Mereu
Diagnostics 2024, 14(5), 509; https://doi.org/10.3390/diagnostics14050509

“Exploring Immune-Related Gene Profiling and Infiltration of Immune Cells in Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma”
by Jialu Li and Juqun Xi
Genes 2024, 15(1), 121; https://doi.org/10.3390/genes15010121

“Pain in High-Dose-Rate Brachytherapy for Cervical Cancer: A Retrospective Cohort Study”
by Ángel Becerra-Bolaños, Miriam Jiménez-Gil, Mario Federico, Yurena Domínguez-Díaz, Lucía Valencia and Aurelio Rodríguez-Pérez
J. Pers. Med. 2023, 13(8), 1187; https://doi.org/10.3390/jpm13081187

	“Viral Infections, Chronic Inflammation and Carcinogenesis” Guest Editors: Dr. Angioletta Lasagna and Dr. Davide Dalu Submission deadline: 15 February 2026
	“Clinical Management of Cervical Cancer” Guest Editor: Dr. Vanessa Samouëlian Submission deadline: 31 March 2026
	“HPV Vaccine and Cervical Cancer Prevention” Guest Editor: Dr. Andreia Cristina de Melo Submission deadline: 30 April 2026
	“Recent Advances and Strategies for the Management of CIN and HPV Eradication Starategies for the Prevention of Uterine Cervical Cancer” Guest Editor: Dr. Masaru Sakamoto Submission deadline 30 April 2026

World Diabetes Day will take place on 14 November 2025, under the theme “Diabetes and well-being”. Diabetes is a major cause of blindness, kidney failure, heart attack, stroke and lower limb amputation. A healthy diet, physical activity and avoiding tobacco use can prevent or delay type 2 diabetes. In addition, diabetes can be treated and its consequences avoided or delayed with medication, regular screening and treatment for complications.

In recognition of this important day, we recommend the following related articles, Special Issues and journals spanning multidisciplinary fields, including clinical medicine, biology and material sciences. We believe th.at promoting such research contributes to enhanced public awareness of innovative ideas regarding the prevention, treatment and care of diabetes. This World Diabetes Day, 14 November, let us put well-being at the heart of diabetes care and start the change for a better life with diabetes.

“New-Onset Diabetes After Transplantation in Renal Recipients: A Pilot Comparative Study of Immediate vs. Extended-Release Tacrolimus Formulation”
by Ioana Adela Ratiu, Florin Bănică, Corina Moisa, Bianca Pașca, Daniela Gîtea, Iulia Dana Grosu, Gabriel Cristian Bako, Oliviu Voștinaru, Wael Abu Dayyih and Lorena Filip
Pharmaceuticals 2025, 18(10), 1532; https://doi.org/10.3390/ph18101532

“From Current Therapeutics to Multitarget Ligands: A Review of Diabetes Pharmacological Treatments”
by Francesc Cabré, Josep J. Centelles and Marta Cascante
Pharmaceutics 2025, 17(9), 1125; https://doi.org/10.3390/pharmaceutics17091125

“Impact of Antidiabetic Medication on Therapy Outcomes in Metastatic Urothelial Cancer Patients Receiving Enfortumab Vedotin Monotherapy”
by Laila Schneidewind, Bernhard Kiss, Friedemann Zengerling, Annemarie Uhlig, Niklas Klümper, Thomas Büttner, Julia Heinzelbecker, Thomas Elegeert, Cem Aksoy, Cindy Rönnau et al.
Biologics 2025, 5(3), 20; https://doi.org/10.3390/biologics5030020

“Gene–Diet Interactions in Diabetes Mellitus: Current Insights and the Potential of Personalized Nutrition”
by Angeliki Kapellou, Effie Salata, Dimitrios Miltiadis Vrachnos, Sevastiani Papailia and Spiros Vittas
Genes 2025, 16(5), 578; https://doi.org/10.3390/genes16050578

“Anti-Diabetic Therapies and Cancer: From Bench to Bedside”
by Dimitris Kounatidis, Natalia G. Vallianou, Irene Karampela, Eleni Rebelos, Marina Kouveletsou, Vasileios Dalopoulos, Petros Koufopoulos, Evanthia Diakoumopoulou, Nikolaos Tentolouris and Maria Dalamaga
Biomolecules 2024, 14(11), 1479; https://doi.org/10.3390/biom14111479

“Untargeted and Targeted Lipidomics Unveil Dynamic Lipid Metabolism Alterations in Type 2 Diabetes”
by Li Feng, Bingshu He, Jianzhen Xia and Zhonghua Wang
Metabolites 2024, 14(11), 610; https://doi.org/10.3390/metabo14110610

“Quality of Dietetic Patient Education Materials for Diabetes and Gastrointestinal Disorders: Where Can We Do Better?”
by Kelly Lambert, Olivia Hodgson and Claudia Goodman
Dietetics 2024, 3(3), 346-356; https://doi.org/10.3390/dietetics3030026

“Biomaterials Designed to Modulate Reactive Oxygen Species for Enhanced Bone Regeneration in Diabetic Conditions”
by Mingshan Li, Zhihe Zhao and Jianru Yi
J. Funct. Biomater. 2024, 15(8), 220; https://doi.org/10.3390/jfb15080220

“The Interrelationship between Diabetes Mellitus and Emotional Well-Being: Current Concepts and Future Prospects”
by Polyxeni Mangoulia, Charalampos Milionis, Eugenia Vlachou and Ioannis Ilias
Healthcare 2024, 12(14), 1457; https://doi.org/10.3390/healthcare12141457

“Are Hyperglycemia-Induced Changes in the Retina Associated with Diabetes-Correlated Changes in the Brain? A Review from Zebrafish and Rodent Type 2 Diabetes Models”
by Kaylee Augustine-Wofford, Victoria P. Connaughton and Elizabeth McCarthy
Biology 2024, 13(7), 477; https://doi.org/10.3390/biology13070477

“Interleukin-6 as a Director of Immunological Events and Tissue Regenerative Capacity in Hemodialyzed Diabetes Patients”
by Maria-Florina Trandafir, Octavian Savu, Daniela Pasarica, Coralia Bleotu and Mihaela Gheorghiu
Med. Sci. 2024, 12(2), 31; https://doi.org/10.3390/medsci12020031

“Euonymus alatus Extract Reduces Insulin Resistance in db/db Mice by Regulating the PI3K–AKT Pathway”
by Seoung-Uk. Lee, Pallavi Gurung, Til Bahadur Thapa Magar, Junmo Lim, Rajeev Shrestha, Yoon-Hee Kim and Yong-Wan Kim
Int. J. Transl. Med. 2024, 4(2), 286-297; https://doi.org/10.3390/ijtm4020018

“Personalized Diabetes Management with Digital Twins: A Patient-Centric Knowledge Graph Approach”
by Fatemeh Sarani Rad, Rasha Hendawi, Xinyi Yang and Juan Li
J. Pers. Med. 2024, 14(4), 359; https://doi.org/10.3390/jpm14040359

“NAFLD Fibrosis Progression and Type 2 Diabetes: The Hepatic–Metabolic Interplay”
by Simona Cernea
Life 2024, 14(2), 272; https://doi.org/10.3390/life14020272

“Mitochondrial Dysfunction in Diabetes: Shedding Light on a Widespread Oversight”
by Franklyn Nonso Iheagwam, Amarachi Joy Joseph, Eniola Deborah Adedoyin, Olawumi Toyin Iheagwam and Samuel Akpoyowvare Ejoh
Pathophysiology 2025, 32(1), 9; https://doi.org/10.3390/pathophysiology32010009

“Is Tirzepatide the New Game Changer in Type 2 Diabetes?”
by Giuseppe Lisco, Olga Eugenia Disoteo, Vincenzo De Geronimo, Anna De Tullio, Vito Angelo Giagulli, Edoardo Guastamacchia, Giovanni De Pergola, Emilio Jirillo and Vincenzo Triggiani
Endocrines 2024, 5(1), 72-86; https://doi.org/10.3390/endocrines5010005

“Fostering Resilience and Wellness: The Synergy of Mindful Eating and the Mediterranean Lifestyle”
by Efstratios Christodoulou, Georgia-Eirini Deligiannidou, Christos Kontogiorgis, Constantinos Giaginis and Antonios E. Koutelidakis
Appl. Biosci. 2024, 3(1), 59-70; https://doi.org/10.3390/applbiosci3010004

“The Main Risk Factors in Type 2 Diabetes for Cognitive Dysfunction, Depression, and Psychosocial Problems: A Systematic Review”
by Maarja Randväli, Toomas Toomsoo and Jekaterina Šteinmiller
Diabetology 2024, 5(1), 40-59; https://doi.org/10.3390/diabetology5010004

“Chronic Kidney Disease in the Older Adult Patient with Diabetes”
by Raja Ravender, Maria-Eleni Roumelioti, Darren W. Schmidt, Mark L. Unruh and Christos Argyropoulos
J. Clin. Med. 2024, 13(2), 348; https://doi.org/10.3390/jcm13020348