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Journal of Clinical Medicine publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Shaping Modern Gastroenterology: Bridging Advancements in Digestive Endoscopy and Clinical Research
edited by Manuele Furnari and Stefano Kayali
submission deadline 3 Aug 2025 | Viewed by 218 | Submission Open
Keywords: digestive endoscopy; gastrointestinal disorders; endoscopic ultrasound (EUS); endoscopic retrograde cholangiopancreatography (ERCP); therapeutic endoscopy; artificial intelligence; pancreatic and biliary diseases; small bowel pathology; early neoplastic lesions; inflammatory bowel diseases (IBDs); translational gastroenterology; endoscopic submucosal dissection (ESD); per-oral endoscopic myotomy (POEM); endoscopic imaging; gastrointestinal pathophysiology
(This special issue belongs to the Section Gastroenterology & Hepatopancreatobiliary Medicine)
Clinical Advances in Artificial Intelligence in Urology
edited by
submission deadline 10 Aug 2025 | 6 articles | Viewed by 7433 | Submission Open
Keywords: artificial intelligence; deep learning; artificial neural networks; computer; AI; machine learning
(This special issue belongs to the Section Nephrology & Urology)
State of the Art: Catheter Ablation of Atrial Fibrillation
edited by and Cinzia Monaco
submission deadline 10 Aug 2025 | 3 articles | Viewed by 5737 | Submission Open
Keywords: atrial fibrillation; catheter ablation; pulsed-field ablation; supraventricular arrhythmias; atrial substrate
(This special issue belongs to the Section Cardiovascular Medicine)
The Clinical Role of Imaging in Lung Diseases
edited by and Claire Van Ngoc Ty
submission deadline 10 Aug 2025 | 4 articles | Viewed by 4487 | Submission Open
Keywords: lung screening; lung cancer; acute respiratory distress; pulmonary embolism; chronic obstructive pulmonary disease; imaging
(This special issue belongs to the Section Respiratory Medicine)
Immune Dysregulation in Inborn Errors of Immunity: From Allergy to Autoimmunity and Lymphoproliferation submission deadline 10 Aug 2025 | 2 articles | Viewed by 3172 | Submission Open
Keywords: immune dysregulation; immunodeficiency; autoimmunity; allergy; lymphoproliferation; inborn errors of immunity
(This special issue belongs to the Section Immunology)
Clinical Management of Patients with Heart Failure—2nd Edition
edited by
submission deadline 13 Aug 2025 | 9 articles | Viewed by 7793 | Submission Open
Keywords: acute heart failure; chronic heart failure; treatment options; management of heart failure; life style changes; diagnosis of heart failure
(This special issue belongs to the Section Cardiovascular Medicine)
Clinical Updates and Perspectives of Implant Dentistry submission deadline 13 Aug 2025 | 1 articles | Viewed by 4850 | Submission Open
Keywords: osseointegration; soft tissue integration; peri-implant diseases
(This special issue belongs to the Section Dentistry, Oral Surgery and Oral Medicine)
Trends and Prospects in Shoulder and Elbow Surgery
edited by Lorenzo Diaz Balzani, Erika Albo, and
submission deadline 14 Aug 2025 | 6 articles | Viewed by 7170 | Submission Open
Keywords: shoulder; elbow; arthroplasty; arthroscopy; rehabilitation; trauma; minimally invasive; regenerative medicine; implant technology
(This special issue belongs to the Section Orthopedics)
Amyloid: From Heart to Brain submission deadline 15 Aug 2025 | 4 articles | Viewed by 4397 | Submission Open
Keywords: amyloid; heart; brain; interactions; small vessel disease; takotsubo; Alzheimer’ s disease
(This special issue belongs to the Section Cardiology)
Sepsis: Current Updates and Perspectives
edited by Ecaterina Scarlatescu
submission deadline 15 Aug 2025 | 3 articles | Viewed by 4296 | Submission Open
Keywords: sepsis biomarkers; diagnostic tools; cytokines; inflammation; infection; antibiotherapy; blood purification; novel therapies
(This special issue belongs to the Section Intensive Care)
Novel Therapeutic Strategies for Acute Myeloid Leukemia
edited by Giovangiacinto Paterno and
submission deadline 15 Aug 2025 | 3 articles | Viewed by 3068 | Submission Open
Keywords: acute myeloid leukemia; novel treatments; supportive care; quality of life; patients’ outcomes; targeted therapy
(This special issue belongs to the Section Hematology)
Otolaryngology—Head and Neck Surgery: Current Trends and Challenges
edited by and Lorenzo Maria Gaini
submission deadline 15 Aug 2025 | 3 articles | Viewed by 1961 | Submission Open
Keywords: minimally invasive surgery; endoscopy; exoscopy; airway surgery; salivary glands diseases; otitis media; pediatric otolaryngology; head and neck surgery
(This special issue belongs to the Section Otolaryngology)
Oral and Maxillofacial Radiology: Clinical Progress and New Directions
edited by Zbigniew Serafin and
submission deadline 15 Aug 2025 | 3 articles | Viewed by 1949 | Submission Open
Keywords: artificial intelligence (AI); computed-assisted diagnosis (CAD); cone beam computed tomography (CBCT); convolutional neural network (CNN); computed tomography (CT); magnetic resonance (MR); PET-CT
(This special issue belongs to the Section Nuclear Medicine & Radiology)
Cardiac Electrophysiology: Focus on Clinical Practice submission deadline 15 Aug 2025 | 1 articles | Viewed by 1015 | Submission Open
Keywords: cardiomyopathy; arrhythmia; heart rhythm; atrial fibrillation; ventricular tachycardia; sudden cardiac death; mapping; ablation; pulsed field ablation (PFA); device; pacemaker; left bundle branch area pacing (LBBAP); conduction system pacing (CSP); implantable cardioverter-defibrillator (ICD); leadless pacing; extraction
(This special issue belongs to the Section Cardiology)
Diagnosis and Treatment for Bone Tumor
edited by Antonio Ziranu and Luigi Cianni
submission deadline 15 Aug 2025 | 2 articles | Viewed by 1013 | Submission Open
Keywords: bone tumor; oncology; osteosarcoma; chondrosarcoma; megaprosthesis; bone resection; chemotherapy; radiotherapy; sarcoma; custom-made
(This special issue belongs to the Section Orthopedics)
Application of Magnetic Resonance Imaging (MRI) in the Diagnosis, Staging and Follow-Up of Oncological Diseases
edited by
submission deadline 15 Aug 2025 | 1 articles | Viewed by 919 | Submission Open
Keywords: MRI; cancer; oncology; diagnosis; staging; follow-up; radiomics
(This special issue belongs to the Section Nuclear Medicine & Radiology)
The Role of Cardiac Rehabilitation After Myocardial Infarction, Coronary Artery Bypass Surgery, and in Other Cardiac Diseases submission deadline 15 Aug 2025 | Viewed by 246 | Submission Open
Keywords: cardiac rehabilitation; coronary artery disease; myocardial infarction; coronary artery bypass surgery; heart failure; ventricular assist device; heart transplantation; cardiomyopathies; cardiac remodeling; illness perception; treatment adherence; gender difference; biomarkers; endothelial function
(This special issue belongs to the Section Cardiology)
Advances in Traumatic Brain Injury: Causes and Recovery
edited by Antonio Bonora
submission deadline 15 Aug 2025 | Viewed by 160 | Submission Open
Keywords: mild traumatic brain injury; TBI; brain injuries; neuroimaging; rehabilitation
(This special issue belongs to the Section Brain Injury)
Clinical Management and Rehabilitation of Spinal Cord Injury
edited by Tsunehiko Konomi
submission deadline 20 Aug 2025 | 11 articles | Viewed by 27358 | Submission Open
Keywords: spinal cord injury; rehabilitation; diagnosis and prognosis; comprehensive management; social support
(This special issue belongs to the Section Orthopedics)
Clinical Aspects of Return to Sport After Injuries
edited by and
submission deadline 20 Aug 2025 | 6 articles | Viewed by 20871 | Submission Open
Keywords: musculoskeletal system; tissue overload; diagnostic methods; rehabilitation; treatment; injury prevention; return to sport; rehabilitation medicine; sports medicine
(This special issue belongs to the Section Sports Medicine)
Gastrointestinal Cancer: Outcomes and Therapeutic Management
edited by Maximos Frountzas
submission deadline 20 Aug 2025 | 8 articles | Viewed by 14813 | Submission Open
Keywords: surgical oncology; gastrointestinal cancer; esophageal; gastric; hepatic; biliary; pancreatic; colon; rectal; neoplasm
(This special issue belongs to the Section Oncology)
Harnessing Photobiomodulation Light for Therapeutic or Prevention of Human Diseases
edited by
submission deadline 20 Aug 2025 | 5 articles | Viewed by 12830 | Submission Open
Keywords: neurorehabilitation; supportive care for cancer; reproductive health; dental and oral diseases; viral and bacterial diseases; wound care; dermatology; sports rehabilitation; bone and musculoskeletal diseases; PBM mechanism; ophthalmology; stem cells and regenerative medicine; pain and addiction management; PBM-tissue interaction
Cardiovascular and Cerebrovascular Emergencies: Advances in Clinical Research
edited by
submission deadline 20 Aug 2025 | 5 articles | Viewed by 10079 | Submission Open
Keywords: cardiovascular emergencies; neurovascular emergencies; stroke; cardiac arrest; acute myocardial infarction
(This special issue belongs to the Section Cardiovascular Medicine)
Traumatic Brain Injury: Emergency Management, Prevention of Secondary Injury, and Rehabilitation
edited by and Lori Shutter
submission deadline 20 Aug 2025 | 4 articles | Viewed by 8387 | Submission Open
Keywords: traumatic brain injury; neuromonitoring; neurocritical care; neurorehabilitation; secondary injury; outcome; prognostication
(This special issue belongs to the Section Brain Injury)
Recent Developments in Gynecological Endocrinology submission deadline 20 Aug 2025 | 5 articles | Viewed by 7377 | Submission Open
Keywords: amenorrhea; puberty; PCOS; premature ovarian insufficiency; endometriosis; infertility; pregnancy; hormones; menopause
(This special issue belongs to the Section Obstetrics & Gynecology)
New Advances in Prenatal Diagnosis and Newborn Screening submission deadline 20 Aug 2025 | 5 articles | Viewed by 6248 | Submission Open
Keywords: sonographic parameters; molecular markers; extravillous and villous trophoblasts; perinatal ultrasound; serum markers for complications of pregnancy; histopathology of the placenta; neonatal pathological conditions
(This special issue belongs to the Section Obstetrics & Gynecology)
Frailty in the Elderly: Risk Factors, Prevention and Clinical Management
edited by
submission deadline 20 Aug 2025 | 4 articles | Viewed by 5873 | Submission Open
Keywords: sarcopenia; frailty; elderly; geriatrics; personalized medicine
(This special issue belongs to the Section Epidemiology & Public Health)
Endodontic and Periodontal Medicine: Systemic Implications of Oral Infections submission deadline 20 Aug 2025 | 6 articles | Viewed by 4549 | Submission Open
Keywords: dentistry; endodontics; apical periodontitis; endodontic medicine; periodontal disease; periodontal medicine; pulpitis; systemic diseases; root canal treatment
(This special issue belongs to the Section Dentistry, Oral Surgery and Oral Medicine)
Advances in Kidney Transplantation
edited by Pedro Ruiz-Esteban, Domingo Hernández and Veronica López
submission deadline 20 Aug 2025 | 4 articles | Viewed by 4008 | Submission Open
Keywords: kidney transplant; acute rejection; biomarkers; artificial intelligence; post-transplant complications; graft survival
(This special issue belongs to the Section Nephrology & Urology)
Interstitial Lung Disease: From Diagnosis to Treatment
edited by and Tomohisa Baba
submission deadline 20 Aug 2025 | 2 articles | Viewed by 3810 | Submission Open
Keywords: interstitial pneumonia; diagnosis; virus infection; collagen vascular disease-related interstitial pneumonia; differen-tial diagnosis; lung sounds
(This special issue belongs to the Section Respiratory Medicine)
Clinical Management of Salivary Gland Disorders
edited by Masao Yagi
submission deadline 20 Aug 2025 | 4 articles | Viewed by 2925 | Submission Open
Keywords: salivary gland tumour; parotidectomy; nerve monitoring; molecular-targeted therapy; immunotherapy
(This special issue belongs to the Section Otolaryngology)
Liver Transplantation: Current Hurdles and Future Perspectives
edited by
submission deadline 20 Aug 2025 | 3 articles | Viewed by 2650 | Submission Open
Keywords: machine perfusion; donation after circulatory death; liver preservation; living donation; acute-on-chronic liver failure; frailty; liver malignancies; surgical technique; liver transplant recipient care; immunosuppression
(This special issue belongs to the Section General Surgery)
Multiple Sclerosis: Prediction, Diagnosis and Treatment
edited by Rosaria Sacco
submission deadline 20 Aug 2025 | 1 articles | Viewed by 2396 | Submission Open
Keywords: neurological diseases; multiple sclerosis; prodromal symptoms; diagnosis; treatment
(This special issue belongs to the Section Clinical Neurology)
State of the Art in Invasive Vascular Interventions (Second Edition)
edited by and Luca Mezzetto
submission deadline 20 Aug 2025 | 3 articles | Viewed by 2002 | Submission Open
Keywords: coronary artery interventions; non-coronary artery cardiac interventions; open surgical cardiac procedures; endo-vascular interventions; open surgical vascular procedures
(This special issue belongs to the Section Vascular Medicine)
Clinical Advances in Gastrointestinal Inflammation
edited by
submission deadline 20 Aug 2025 | 2 articles | Viewed by 1668 | Submission Open
Keywords: Helicobacter pylori; antibiotic resistance; COVID-19 pandemic; post-COVID era; inflammatory bowel diseases; acute gastrointestinal infections; SARS-COV-2 infection; celiac disease
(This special issue belongs to the Section Gastroenterology & Hepatopancreatobiliary Medicine)
Juvenile Idiopathic Arthritis (JIA): Diagnosis, Treatment and Latest Updates
edited by
submission deadline 20 Aug 2025 | 1 articles | Viewed by 1449 | Submission Open
Keywords: juvenile idiopathic arthritis; pathophysiology; genetic predisposition; immunologic abnormalities; diagnosis; treatment; outcome
(This special issue belongs to the Section Clinical Pediatrics)
Advancements and Challenges in Managing Hepato-Pancreato-Biliary Cancers
edited by and Niccolò Petrucciani
submission deadline 20 Aug 2025 | 1 articles | Viewed by 1437 | Submission Open
Keywords: liver; pancreas; HPB technology; artificial intelligence for HPB; surgical oncology; MIS
(This special issue belongs to the Section Gastroenterology & Hepatopancreatobiliary Medicine)
Cardio-Oncology: Novel Concepts in Diagnosis, Prevention and Treatment of Cardiotoxicity, from Gender Differences and Beyond (Second Edition) submission deadline 20 Aug 2025 | 1 articles | Viewed by 1262 | Submission Open
Keywords: cardio-oncology; cardiotoxicity; gender medicine; chemotherapy; radiotherapy; immune and targeted therapeutics; physical activity; quality of life
(This special issue belongs to the Section Cardiovascular Medicine)
Clinical Updates in Trauma and Emergency Medicine
edited by Yong-Soo Cho and Hyun Ho Ryu
submission deadline 20 Aug 2025 | 2 articles | Viewed by 1220 | Submission Open
Keywords: emergency medicine; epidemiology; cardiovascular disease
(This special issue belongs to the Section Emergency Medicine)
Mental Disorders, Cognitive Impairment and Dementia Among Older Adults submission deadline 20 Aug 2025 | 1 articles | Viewed by 1153 | Submission Open
Keywords: mental disorders; cognitive decline; dementia; older adults; mental health; exercise; physical function
(This special issue belongs to the Section Geriatric Medicine)
Neurosurgery: Recent Advances and New Perspectives in Skull Base Approaches
edited by Sèbastien Froelich and Matteo De Simone
submission deadline 20 Aug 2025 | 1 articles | Viewed by 1049 | Submission Open
Keywords: skull base; neuroanatomy; tumors; augmented reality; ETOA; EEA; exoscopy; endoscopy; multi-portal approaches
(This special issue belongs to the Section Clinical Neurology)
Non-Invasive Respiratory Support: Current Insights and Future Directions
edited by Giovanni Misseri and
submission deadline 20 Aug 2025 | 1 articles | Viewed by 675 | Submission Open
Keywords: respiratory failure; high-flow nasal cannula (HFNC); noninvasive ventilation (NIV); noninvasive positive pressure ventilation (NPPV); hypoxia; perioperative care; weaning; ICU; respiratory care; respiratory physiology; pneumology; home-care ventilation; artificial intelligence; personalized medicine
(This special issue belongs to the Section Respiratory Medicine)
Surgical Precision: The Impact of AI and Robotics in General Surgery
edited by Tamara M. H. Gall
submission deadline 20 Aug 2025 | 1 articles | Viewed by 575 | Submission Open
Keywords: robotic surgery; artificial intelligence in surgery; surgical training; AR in surgery; 3D imaging; surgical navigation
(This special issue belongs to the Section General Surgery)
Integrating Psychological Science into Chronic Pain Management: Emerging Approaches and Insights
edited by Scott G. Ravyts and Margot De Kooning
submission deadline 20 Aug 2025 | 1 articles | Viewed by 489 | Submission Open
Keywords: chronic primary pain; nociplastic pain; coping strategies; depression; anxiety; trauma
(This special issue belongs to the Section Mental Health)
Diabetic Nephropathy: Advances in Pathogenesis and Novel Therapies
edited by Meritxell Ibernon
submission deadline 20 Aug 2025 | Viewed by 296 | Submission Open
Keywords: pathogenesis of diabetic nephropathy; novel therapies; risk factors for disease progression; proteomic approach; serologic biomarkers; histological classification
(This special issue belongs to the Section Nephrology & Urology)
Management of Pregnancy Complications: 2nd Edition
edited by Ariel Many
submission deadline 20 Aug 2025 | Viewed by 178 | Submission Open
Keywords: high-risk pregnancy; preterm labor; fetal growth restriction; gestational diabetes; twins; hypertensive disorders during pregnancy; preeclampsia; IUGR; prenatal genetics; congenital anomaly detection; cesarean section; complications of labor and delivery
(This special issue belongs to the Section Obstetrics & Gynecology)
Clinical Advancements in Preoperative Optimization for Patients Undergoing Colorectal Surgery
edited by Tim Lubbers
submission deadline 20 Aug 2025 | Viewed by 140 | Submission Open
Keywords: preoperative optimization; colorectal surgery; postoperative recovery; complication; clinical innovations; patient outcome
(This special issue belongs to the Section Gastroenterology & Hepatopancreatobiliary Medicine)
Catheter Ablation for Cardiac Arrhythmias: Clinical Updates and Perspectives in Cardiac Electrophysiology
edited by Karolina Weinmann-Emhardt, Ingo Staudacher and Jonas Wormann
submission deadline 21 Aug 2025 | 1 articles | Viewed by 2748 | Submission Open
Keywords: electrophysiology; arrhythmia; atrial fibrillation; atrial flutter; ablation; 3D mapping; pulsed field ablation; radiofrequency ablation; pulmonary vein isolation
(This special issue belongs to the Section Cardiovascular Medicine)
Eosinophilic Esophagitis: Clinical Advances in Diagnosis, Treatment, and Monitoring
edited by Pierfrancesco Visaggi, Edoardo Vincenzo Savarino and
submission deadline 21 Aug 2025 | 1 articles | Viewed by 1562 | Submission Open
Keywords: eosinophilic esophagitis (EoE); diagnosis  ; treatment  ; monitoring; disease assessment; precision medicine
(This special issue belongs to the Section Gastroenterology & Hepatopancreatobiliary Medicine)
Acute Pancreatitis: Clinical Management and Treatment submission deadline 21 Aug 2025 | 2 articles | Viewed by 948 | Submission Open
Keywords: acute pancreatitis; classification; complications; intervention; management; prevention; severity; treatment
(This special issue belongs to the Section Gastroenterology & Hepatopancreatobiliary Medicine)
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