Special Issues

Journal of Clinical Medicine publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue polices and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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New Insights into Type 1 Diabetes
edited by Antonio J. Amor and Verónica Perea
submission deadline 10 Sep 2024 | 4 articles | Viewed by 4944 | Submission Open
Keywords: type 1 diabetes; insulin resistance; cardiovascular disease; cardiovascular risk; metabolic syndrome; continuous glucose monitoring; atherosclerosis; biomarkers
(This special issue belongs to the Section Endocrinology & Metabolism)
Recent Advances in Transcatheter Aortic Valve Replacement
edited by Maciej Dąbrowski and
submission deadline 10 Sep 2024 | 4 articles | Viewed by 4222 | Submission Open
Keywords: aortic stenosis; transcatheter; bioprosthesis; TAVI; Transcatheter aortic valve replacement
(This special issue belongs to the Section Cardiovascular Medicine)
Musculoskeletal Infections: Clinical Diagnosis and Treatment submission deadline 10 Sep 2024 | 2 articles | Viewed by 2320 | Submission Open
Keywords: computed tomography; magnetic resonance; musculoskeletal infections; septic arthritis; osteomyelitis; fungal infections; mycobacterium infections; prosthetic joint infections; postoperative infections; surgical treatment; VAC; hyperbaric oxygen
(This special issue belongs to the Section Orthopedics)
Colorectal Cancer: Clinical Practices and Challenges
edited by Muhammad Aziz
submission deadline 10 Sep 2024 | 2 articles | Viewed by 2085 | Submission Open
Keywords: colon cancer; rectal cancer; colonoscopy; diagnosis; management; prevention; innovation; technology; artificial intelligence
(This special issue belongs to the Section Oncology)
Clinical Application of Established and Emerging Biomarkers for Cardiopulmonary Diseases submission deadline 10 Sep 2024 | 1 articles | Viewed by 1264 | Submission Open
Keywords: chronic obstructive pulmonary disease; severe asthma; biomarkers; metabolomics; endothelial function; arterial stiffness; cardiovascular risk
(This special issue belongs to the Section Clinical Laboratory Medicine)
Advances in the Diagnosis and Management of Age-Related Macular Degeneration
edited by Tsutomu Yasukawa
submission deadline 15 Sep 2024 | 19 articles | Viewed by 22474 | Submission Open
Keywords: age-related macular degeneration; angiography; anti-vascular endothelial growth factor therapy; choroidal neovascularization; geographic atrophy; multi-modal imaging; ophthalmology; optical coherence tomography; photodynamic therapy; retinal pigment epithelium
(This special issue belongs to the Section Ophthalmology)
Current Topics in Endodontics
edited by
submission deadline 15 Sep 2024 | 5 articles | Viewed by 16379 | Submission Open
(This special issue belongs to the Section Dentistry, Oral Surgery and Oral Medicine)
Gastric Cancer: Diagnosis, Treatment and Prevention
edited by
submission deadline 15 Sep 2024 | 9 articles | Viewed by 10761 | Submission Open
Keywords: gastric cancer; diagnosis; treatment; prevention; IEE; ESD; Helicobacter pylori
(This special issue belongs to the Section Gastroenterology & Hepatopancreatobiliary Medicine)
Corneal Transplantation: Recent Advances and Current Perspectives
edited by and
submission deadline 15 Sep 2024 | 8 articles | Viewed by 8489 | Submission Open
Keywords: cornea transplantation; keratoconus; endothelial dystrophy; imaging; cataract; refractive surgery; artificial intelligence; devices; research; tissue engineering
(This special issue belongs to the Section Ophthalmology)
Recent Advances in the Management of Pathological Fractures
edited by Giulio Maccauro and
submission deadline 15 Sep 2024 | 7 articles | Viewed by 7350 | Submission Open
Keywords: pathological fracture; metastasis; genetic disease; sarcoma; infection; rheumatic disease; bone tumor; insufficiency fractures
(This special issue belongs to the Section Orthopedics)
New Insights from Cardiopulmonary Exercise Testing and Cardiac Rehabilitation—Part II
edited by
submission deadline 15 Sep 2024 | 5 articles | Viewed by 6141 | Submission Open
Keywords: cardiac rehabilitation; exercise physiology; exercise performance; exercise testing; physical activity assessment; exercise; physical activity; oxygen consumption; cardiopulmonary exercise testing
(This special issue belongs to the Section Cardiology)
Potentially Malignant Disorders and Cancers of Head and Neck Region—Series 2 submission deadline 15 Sep 2024 | 3 articles | Viewed by 4975 | Submission Open
Keywords: autofluorescence; vital staining; chemiluminescence light; laser-induced fluorescence; liquid biopsy; optical coherence tomography; contact endoscopy; narrow-band imaging (NBI) endoscopy; saliva; biomarkers; high-resolution sonography; precision medicine; LOH; SNPs; predictives; prognostic; diagnostic; head and neck cancers; oral potentially malignant disorders
(This special issue belongs to the Section Oncology)
Urologic Oncology: From Diagnosis to Treatments submission deadline 15 Sep 2024 | 3 articles | Viewed by 3997 | Submission Open
Keywords: prostate cancer; bladder cancer; upper tract urothelial cancer; testicular cancer; renal cancer; adrenal cancer; penis cancer; robotic surgery; personalized medicine
(This special issue belongs to the Section Nephrology & Urology)
Vasculitis: Current Treatment and Future Options
edited by Carlos García-Porrúa
submission deadline 15 Sep 2024 | 3 articles | Viewed by 3915 | Submission Open
Keywords: vasculitis treatment; tocilizumab; mepolizumab; avacopan; apremilast; baricitinib; abatacept; rituximab
(This special issue belongs to the Section Immunology)
Advances in Gynecological Laparoscopic Surgery submission deadline 15 Sep 2024 | 3 articles | Viewed by 3552 | Submission Open
Keywords: endometrial cancer; ovarian cancer; cervical cancer; infertility; myomas; hysteroscopy; endometriosis; postoperative outcomes and advantages; cost-effectiveness; uterus prolapse; obstetric-related emergencies
(This special issue belongs to the Section Obstetrics & Gynecology)
Clinical Imaging and Newest Therapies for Prostate Cancer
edited by , Ruban Thanigasalam and Scott Leslie
submission deadline 15 Sep 2024 | 3 articles | Viewed by 3430 | Submission Open
Keywords: prostate; cancer; multiphoton; PSMA; MRI; lymphadenectomy
(This special issue belongs to the Section Nephrology & Urology)
Clinical Management of Colorectal and Rectal Surgery
edited by Tim Lubbers
submission deadline 15 Sep 2024 | 2 articles | Viewed by 2896 | Submission Open
Keywords: colorectal surgery; surgical management; surgical techniques; laparoscopic surgery; patient outcome
(This special issue belongs to the Section Gastroenterology & Hepatopancreatobiliary Medicine)
Clinical Research in Viral Hepatitis submission deadline 15 Sep 2024 | 2 articles | Viewed by 2456 | Submission Open
Keywords: HCV; HBV; HDV; HEV; HAV; clinical issues; antiviral resistance; clinical outcome
(This special issue belongs to the Section Gastroenterology & Hepatopancreatobiliary Medicine)
Clinical Advances in Ischemic Heart Disease
edited by Stefano Schena and
submission deadline 15 Sep 2024 | 2 articles | Viewed by 2080 | Submission Open
Keywords: multidisciplinary approach; modern imaging; myocardial pre-habilitation; revascularization in severe ischemic cardiomyopathy; guidelines; complex PCI; hybrid treatment; minimally invasive surgery
(This special issue belongs to the Section Cardiology)
The Latest Research in Clinical Neuroradiology
edited by
submission deadline 15 Sep 2024 | 1 articles | Viewed by 1080 | Submission Open
Keywords: fMRI; neuroimaging; stroke; tumor; multiple sclerosis; amyotrophic lateral sclerosis; neurodegeneration; autism spectrum disorder (ASD); psychiatric disorders
(This special issue belongs to the Section Nuclear Medicine & Radiology)
Clinical Advances in Inflammatory Heart Diseases
edited by Ioanna Koniari
submission deadline 15 Sep 2024 | Viewed by 168 | Submission Open
Keywords: inflammation; inflammatory cardiac disease; myocarditis; pericarditis; endocarditis; sarcoidosis; amyloidosis
(This special issue belongs to the Section Cardiology)
Clinical Applications of Tumor Immunotherapy
edited by and Elisa Andrini
submission deadline 16 Sep 2024 | 3 articles | Viewed by 4745 | Submission Open
Keywords: immunotherapy; PD-1/PD-L1; CTLA-4; novel biomarkers; personalized oncology; tumor vaccine; cell therapy; adoptive immunotherapy; T cell engagers
(This special issue belongs to the Section Oncology)
Advances in Clinical Exercise, Rehabilitation and Cardiorespiratory Physiology
edited by Gaël Deboeck and
submission deadline 16 Sep 2024 | 1 articles | Viewed by 820 | Submission Open
Keywords: exercise physiology; cardiorespiratory physiology; cardiorespiratory rehabilitation; exercise testing; rehabilitation
(This special issue belongs to the Section Pulmonology)
New Insights into Acute Care and Emergency Surgery
edited by Jacob Chen and Avi Benov
submission deadline 17 Sep 2024 | 3 articles | Viewed by 3657 | Submission Open
Keywords: trauma surgery; emergency surgery; acute care; anesthesia; ICU
(This special issue belongs to the Section General Surgery)
Clinical Management of Chronic Pain
edited by Mariateresa Giglio
submission deadline 18 Sep 2024 | 8 articles | Viewed by 16133 | Submission Open
Keywords: chronic pain; opioid; pain therapy; neuropathic pain; interventional techniques
(This special issue belongs to the Section Anesthesiology)
Diagnosis and Treatment of Connective Tissue Diseases: A Clinician's Perspective
edited by , Aleksandra Dańczak-Pazdrowska and
submission deadline 19 Sep 2024 | 4 articles | Viewed by 7201 | Submission Open
Keywords: connective tissue diseases; lupus erythematosus; scleroderma; dermatomyositis; MCTD; clinical picture; spectrum of clinical symptoms; treatment; complications; clinical follow-up
(This special issue belongs to the Section Immunology)
Valvular Heart Disease: From Basic to Clinical Advances
edited by
submission deadline 20 Sep 2024 | 15 articles | Viewed by 25006 | Submission Open
Keywords: lipoproteins; PCSK9; aortic valve; calicification; progression of aortic stenosis; ECM-lipid retention
(This special issue belongs to the Section Cardiovascular Medicine)
Clinical Research of Novel Therapeutic Approaches in Dentistry submission deadline 20 Sep 2024 | 12 articles | Viewed by 14466 | Submission Open
Keywords: oral medicine; tissue regeneration; lasers; photobiomodulation; periodontology; dentistry; biological safety
(This special issue belongs to the Section Dentistry, Oral Surgery and Oral Medicine)
Acute Myeloid Leukemia: Latest Advances in the Diagnostics, Therapeutic Strategies and Clinical Management
edited by Michael D. Diamantidis
submission deadline 20 Sep 2024 | 7 articles | Viewed by 13552 | Submission Open
Keywords: ELN; ICC and WHO 2022 AML classifications; molecular AML diagnostics; AML biology; measurable residual disease (MRD); novel targeted AML therapies; AML immunotherapies; hematopoietic stem cell transplantation (HSCT)
(This special issue belongs to the Section Hematology)
Orthopaedic Trauma Surgery: Diagnosis, Treatment and Outcome submission deadline 20 Sep 2024 | 7 articles | Viewed by 9189 | Submission Open
Keywords: fracture; malunion; nonunion; locking plate; intramedullary nail; osteoporotic fracture; polytrauma
(This special issue belongs to the Section Orthopedics)
Clinical Research Progress on the Gilles de la Tourette Syndrome submission deadline 20 Sep 2024 | 4 articles | Viewed by 6740 | Submission Open
Keywords: Gilles de la Tourette Syndrome; tic disorders; provisional tic disorders; therapy; psychopharmacology; endocrinology; cognitive-behavioral treatment; comprehensive behavioral intervention for Tics; habit reversal; comorbidity; brain/anatomy and histology; functional connectivity; electroencephalography/event-related potentials; fMRI; neuropsychology; neurology; clinical psychology; psychophysiology
(This special issue belongs to the Section Mental Health)
Veno-Venous Extracorporeal Membrane Oxygenation (ECMO): Future Application in the Critical Care and Anesthesia
edited by , Davide Colombo and Rachele Simonte
submission deadline 20 Sep 2024 | 5 articles | Viewed by 6552 | Submission Open
Keywords: VV ECMO; carbon dioxide (CO2) exchange; advanced monitoring; ECMO team; respiratory distress; trialing off; weaning; rescue therapy
(This special issue belongs to the Section Intensive Care)
Advances in Laparoscopic and Robotic Surgery in Urology
edited by Mariaconsiglia Ferriero and
submission deadline 20 Sep 2024 | 6 articles | Viewed by 6301 | Submission Open
Keywords: robotics; laparoscopy; cystectomy; partial nephrectomy; prostatectomy
(This special issue belongs to the Section Nephrology & Urology)
Trends and Prospects in Cardiac MRI
edited by
submission deadline 20 Sep 2024 | 4 articles | Viewed by 5926 | Submission Open
Keywords: cardiac magnetic resonance; cardiomyopathies; heart failure; myocardial fibrosis; tissue composition; hybrid imaging; artificial intelligence
(This special issue belongs to the Section Nuclear Medicine & Radiology)
Clinical Diagnosis and Treatment of Epilepsy submission deadline 20 Sep 2024 | 4 articles | Viewed by 4688 | Submission Open
Keywords: epilepsy; misdiagnosis in epilepsy; awareness in epilepsy; treatment in epilepsy; unmet needs in epilepsy; antiseizure medications; epilepsy surgery; neurostimulation
(This special issue belongs to the Section Brain Injury)
Advances in Diagnosis and Treatment of Gynecological Malignancies: Part II
edited by
submission deadline 20 Sep 2024 | 2 articles | Viewed by 4308 | Submission Open
Keywords: gynecological malignancies; histopathology; next-generation sequencing; theranostics; targeted therapy; robotics; personalized medicine
(This special issue belongs to the Section Obstetrics & Gynecology)
Clinical Innovations in Digestive Disease Diagnosis and Treatment
edited by and Angelo Benevento
submission deadline 20 Sep 2024 | 4 articles | Viewed by 3969 | Submission Open
Keywords: gastroenterology; digestive diseases; gastrointestinal endoscopy; upper  GI surgery; colorectal surgery; hepatobiliary surgery; anastomotic leakage; gastrointestinal surgical oncology; inflammatory bowel disease; precision medicine in gastroenterology; minimally invasive gastrointestinal procedures; SIPAD congress contributions
(This special issue belongs to the Section Gastroenterology & Hepatopancreatobiliary Medicine)
New Insights in Critical Care Cardiology submission deadline 20 Sep 2024 | 2 articles | Viewed by 3349 | Submission Open
Keywords: atrial fibrillation; arrhythmia surgery; CIEDs therapy; valvular surgery (including TAVR); risk stratification of cardiovascular surgery; interventional valve therapy; pulmonary hypertension; balloon angioplasty
(This special issue belongs to the Section Cardiology)
The Rising Concern of Rectal Cancer: Causes, Diagnosis and Treatment Options
edited by Carlo Vallicelli
submission deadline 20 Sep 2024 | 2 articles | Viewed by 3182 | Submission Open
Keywords: rectal cancer; robotic surgery; transanal TME; colo-rectal carcinomatosis; chemotherapy; radiotherapy
(This special issue belongs to the Section Gastroenterology & Hepatopancreatobiliary Medicine)
Clinical Diagnosis and Treatment of Schizophrenia
edited by Nathalie Coulon
submission deadline 20 Sep 2024 | 3 articles | Viewed by 2916 | Submission Open
Keywords: schizophrenia; early-onset schizophrenia; very early-onset schizophrenia; diagnosis; care
(This special issue belongs to the Section Mental Health)
Cardiac Arrhythmias in Clinical Practice
edited by
submission deadline 20 Sep 2024 | 2 articles | Viewed by 2875 | Submission Open
Keywords: histology of myocardial substrate; pathology of conduction tissue; potential biomarkers of cardiac arrhythmias (i.e.; serum determination of antibodies for the intercalated disk); anti-arrhythmic drugs; mapping and ablation of arrhythmic foci; ICD implantation (implantable cardioverter defibrillator)
(This special issue belongs to the Section Cardiology)
Precancerous Cervical Lesions: Screening, Diagnosis and Clinical Practice
edited by Demetra Gabriela Socolov, Liana Pleş and
submission deadline 20 Sep 2024 | 1 articles | Viewed by 2633 | Submission Open
Keywords: cervical precancer; colposcopy; cervical cancer screening; risk stratification; HPV; vaginal microbiota; methylation markers; immunocytochemistry; artificial intelligence in colposcopy
(This special issue belongs to the Section Obstetrics & Gynecology)
Colorectal Cancer: Current Concept and Emerging Treatments
edited by
submission deadline 20 Sep 2024 | 2 articles | Viewed by 2541 | Submission Open
Keywords: colorectal cancer; robotic; minimally invasive; total neoadjuvant therapy; neoadjuvant immunotherapy; watch and wait; adjuvant chemotherapy
(This special issue belongs to the Section Gastroenterology & Hepatopancreatobiliary Medicine)
Health and Disease in the Retinas and Optic Nerves—for Up-to-Date Practitioners, 2nd Edition
edited by Shree K Kurup and
submission deadline 20 Sep 2024 | 1 articles | Viewed by 2105 | Submission Open
Keywords: gene; protein; cell; eye; therapy; diagnosis
(This special issue belongs to the Section Ophthalmology)
Polytrauma Management under Special Circumstances: Pediatric Trauma, Trauma in Pregnancy and Geriatric Trauma
edited by Kai Oliver Jensen and Arnold J. Suda
submission deadline 20 Sep 2024 | 2 articles | Viewed by 1937 | Submission Open
Keywords: polytrauma; geriatric; pregnancy; children; severely injured; orthogeriatric; paediatric; trauma; outcome
(This special issue belongs to the Section General Surgery)
The Epidemiology and Effects of Cardiovascular Risk Factors in Athletes
edited by Giuseppe Di Gioia, Maria Rosaria Squeo and
submission deadline 20 Sep 2024 | 2 articles | Viewed by 1927 | Submission Open
Keywords: athletes; dyslipidemia; hypertension; cholesterol; prevention; risk factors; sport cardiology
(This special issue belongs to the Section Cardiovascular Medicine)
Advances in Allergic Diseases and Asthma: Clinical Insights and Emerging Therapies
edited by
submission deadline 20 Sep 2024 | 2 articles | Viewed by 1808 | Submission Open
Keywords: allergic diseases; asthma management; airway obstruction; allergy diagnosis; angioedema; urticaria
(This special issue belongs to the Section Immunology)
Clinical Diagnosis and Treatment of Gynecologic Oncology
edited by and Marco D'Indinosante
submission deadline 20 Sep 2024 | 2 articles | Viewed by 1588 | Submission Open
Keywords: gynecologic oncology; minimally invasive surgery; sentinel lymph node; fertility-spring surgery; molecular biology
(This special issue belongs to the Section Obstetrics & Gynecology)
Thromboembolic Disease and Antithrombotic Therapy
edited by Prahlad Ho
submission deadline 20 Sep 2024 | 1 articles | Viewed by 1521 | Submission Open
Keywords: thrombosis; pulmonary embolism; manticoagulation; DOAC (direct oral anticoagulants); DVT (deep vein thrombosis); novel anticoagulants (factor XIa inhibitors); thrombin; fibrin generation; risk stratification; biomarkers; Virchow’ s triad; post thrombotic syndrome
(This special issue belongs to the Section Hematology)
Cardiac Ablation: Current Status and Future Perspectives
edited by Fabrizio Guarracini and Alberto Preda
submission deadline 20 Sep 2024 | 2 articles | Viewed by 1431 | Submission Open
Keywords: catheter ablation; tachycardia; 3D electroanatomic mapping systems; intracardiac echocardiography; steerable catheters; cerebral protection devices
(This special issue belongs to the Section Cardiology)
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