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13 August 2025
Journal of Clinical Medicine | Highly Cited Papers Published in 2024 and Hot Topic Special Issues in the “Emergency Medicine” Section


We are pleased to introduce the highly cited papers and hot Special Issues in the “Emergency Medicine” Section of Journal of Clinical Medicine (JCM, ISSN: 2077-0383).  Our “Emergency Medicine” Section’s goal is to improve the quality of care by publishing high-quality research for emergency medicine and related specialties by publishing original research related to the practice and research of emergency medicine. The subject areas include, but are not limited to, the following:

  • Triage;
  • Disposition;
  • Risk-stratification;
  • General emergency medicine;
  • Acute pain;
  • Out-of-hospital emergency medical services;
  • Pediatric emergency medicine;
  • Geriatric emergency medicine;
  • Emerging new diseases;
  • Injury and disease prevention.

For more details about this section and to access the latest publications, please visit: https://www.mdpi.com/journal/jcm/sections/Emergency_Med.

1. “Acute Lung Injury after Cardiopulmonary Resuscitation: A Narrative Review”
by Giuseppe Marchese, Elisabetta Bungaro, Aurora Magliocca, Francesca Fumagalli, Giulia Merigo, Federico Semeraro, Elisa Mereto, Giovanni Babini, Erik Roman-Pognuz, Giuseppe Stirparo et al.
J. Clin. Med. 2024, 13(9), 2498; https://doi.org/10.3390/jcm13092498
Full text available online: https://www.mdpi.com/2077-0383/13/9/2498

2. “Pulmonary Embolism in Pregnancy: A Review for Clinical Practitioners”
by Agata  Makowska, Thomas Treumann, Stefan Venturini and Michael Christ
J. Clin. Med. 2024, 13(10), 2863; https://doi.org/10.3390/jcm13102863
Full text available online: https://www.mdpi.com/2077-0383/13/10/2863

3. “Improved Extracorporeal Cardiopulmonary Resuscitation (ECPR) Outcomes are Associated with a Restrictive Patient Selection Algorithm”
by Benjamin Assouline, Nathalie Mentha, Hannah Wozniak, Viviane Donner, Carole Looyens, Laurent Suppan, Robert Larribau, Carlo Banfi, Karim Bendjelid and Raphaël Giraud
J. Clin. Med. 2024, 13(2), 497; https://doi.org/10.3390/jcm13020497
Full text available online: https://www.mdpi.com/2077-0383/13/2/497

4. “The Use of Thrombectomy during Primary Percutaneous Coronary Intervention: Resurrecting an Old Concept in Contemporary Practice”
by Zahir Satti, Muntaser Omari, Bilal Bawamia, Timothy Cartlidge, Mohaned Egred, Mohamed Farag and Mohammad Alkhalil
J. Clin. Med. 2024, 13(8), 2291; https://doi.org/10.3390/jcm13082291
Full text available online: https://www.mdpi.com/2077-0383/13/8/2291

5. “Traumatic Brain Injury in Patients under Anticoagulant Therapy: Review of Management in Emergency Department”
by Vincenzo G. Menditto, Giulia Rossetti, Mattia Sampaolesi, Marta Buzzo and Giovanni Pomponio
J. Clin. Med. 2024, 13(13), 3669; https://doi.org/10.3390/jcm13133669
Full text available online: https://www.mdpi.com/2077-0383/13/13/3669

6. “Evaluation of New Cardiac Damage Biomarkers in Polytrauma: GDF-15, HFABP and uPAR for Predicting Patient Outcomes”
by Aileen Ritter, Lorenz Lötterle, Jiaoyan Han, Miriam Kalbitz, Dirk Henrich, Ingo Marzi, Liudmila Leppik and Birte Weber
J. Clin. Med. 2024, 13(4), 961; https://doi.org/10.3390/jcm13040961
Full text available online: https://www.mdpi.com/2077-0383/13/4/961

7. “Cardiac Arrest Mortality and Disposition Patterns in United States Emergency Departments”
by Kenneth M. Zabel, Mohammed A. Quazi, Katarina Leyba, Alexandra C. Millhuff, Mikel Madi, Wilfredo Henriquez Madrid, Aman Goyal, Muhammad Ibraiz Bilal, Amir H. Sohail, Shazib Sagheer et al.
J. Clin. Med. 2024, 13(18), 5585; https://doi.org/10.3390/jcm13185585
Full text available online: https://www.mdpi.com/2077-0383/13/18/5585

8. “Evolution of Cardiogenic Shock Management and Development of a Multidisciplinary Team-Based Approach: Ten Years Experience of a Single Center”
by Leonardo Belfioretti, Matteo Francioni, Ilaria Battistoni, Luca Angelini, Maria Vittoria Matassini, Giulia Pongetti, Matilda Shkoza, Luca Piangerelli, Tommaso Piva, Elisa Nicolini et al.
J. Clin. Med. 2024, 13(7), 2101; https://doi.org/10.3390/jcm13072101
Full text available online: https://www.mdpi.com/2077-0383/13/7/2101

9. “Vasopressor Therapy”
by Jean-Louis Vincent and Filippo Annoni
J. Clin. Med. 2024, 13(23), 7372; https://doi.org/10.3390/jcm13237372
Full text available online: https://www.mdpi.com/2077-0383/13/23/7372

10. “The Multidisciplinary Mobile Unit (MMU) Program Bringing Hospital Specialist Geriatric Competencies at Home: A Feasible Alternative to Admission in Older Patients with Urgent Complaints”
by Antonio Nouvenne, Andrea Ticinesi, Carmine Siniscalchi, Martina Rendo, Nicoletta Cerundolo, Alberto Parise, Giampiero Castaldo, Giulia Chiussi, Richard Carrassi, Angela Guerra et al.
J. Clin. Med. 2024, 13(9), 2720; https://doi.org/10.3390/jcm13092720
Full text available online: https://www.mdpi.com/2077-0383/13/9/2720

Special Issues:
Cardiopulmonary Resuscitation—from Research to Clinical Implementation
Guest Editor: Prof. Dr. Endre Zima
Submission deadline: 20 November 2025
Recent Advances in Therapy of Trauma and Surgical Critical Care
Guest Editor: Dr. Rita Galeiras
Submission deadline: 20 December 2025
New Advances in Extracorporeal Membrane Oxygenation (ECMO)
Guest Editor: Dr. Camilla L’Acqua
Submission deadline: 20 December 2025
New Insights in Trauma and Emergency Surgery
Guest Editors: Dr. Kai Oliver Jensen
and Prof. Dr. Valentin Neuhaus
Submission deadline: 20 February 2026

5 August 2025
Journal of Clinical Medicine | Highly Cited Papers and Hot Topic Special Issues on Stroke


Stroke is an acute nervous system disease caused by a variety of factors, such as cerebral vascular damage and focal or whole brain damage, and it has become a threat to global health. At present, medical research is deeply involved in the fields of early detection and timely intervention of stroke, prognosis management, and rehabilitation intervention, which injects new impetus into helping patients recover their functions, reduce recurrence, and improve their quality of life. We welcome you to read the following highly cited papers published in the Journal of Clinical Medicine (JCM, ISSN: 2077-0383), and hope that these articles can bring new ideas for stroke research. In addition, some Special Issues on this topic are currently open for submission.

1. “The Impact of Anti-Amyloid Immunotherapies on Stroke Care”
by Philippe A. Bilodeau, John R. Dickson and Mariel G. Kozberg
J. Clin. Med. 2024, 13(5), 1245; https://doi.org/10.3390/jcm13051245
Full text available online: https://www.mdpi.com/2077-0383/13/5/1245

2. “Sex-Related Differences in Mortality, Delayed Cerebral Ischemia, and Functional Outcomes in Patients with Aneurysmal Subarachnoid Hemorrhage: A Systematic Review and Meta-Analysis”
by Sarah Berli, Massimo Barbagallo, Emanuela Keller, Giuseppe Esposito, Alberto Pagnamenta and Giovanna Brandi
J. Clin. Med. 2024, 13(10), 2781; https://doi.org/10.3390/jcm13102781
Full text available online: https://www.mdpi.com/2077-0383/13/10/2781

3. “Benefits of Robot-Assisted Upper-Limb Rehabilitation from the Subacute Stage after a Stroke of Varying Severity: A Multicenter Randomized Controlled Trial”
by So Young Ahn, Soo-Kyung Bok, Ji Young Lee, Hyeon Woo Ryoo, Hoo Young Lee, Hye Jung Park, Hyun Mi Oh and Tae-Woo Kim
J. Clin. Med. 2024, 13(3), 808; https://doi.org/10.3390/jcm13030808
Full text available online: https://www.mdpi.com/2077-0383/13/3/808

4. “Blood Pressure Variability in Acute Stroke: A Narrative Review”
by Christina Zompola, Lina Palaiodimou, Konstantinos Voumvourakis, Leonidas Stefanis, Aristeidis H. Katsanos, Else C. Sandset, Estathios Boviatsis and Georgios Tsivgoulis
J. Clin. Med. 2024, 13(7), 1981; https://doi.org/10.3390/jcm13071981
Full text available online: https://www.mdpi.com/2077-0383/13/7/1981

5. “Effectiveness of Virtual Reality in Occupational Therapy for Post-Stroke Adults: A Systematic Review”
by Síbila Floriano Landim, Roberto López, Antonia Caris, Constanza Castro, Ramon D. Castillo, Daniela Avello, Braulio Henrique Magnani Branco, Pablo Valdés-Badilla, Florencia Carmine, Cristian Sandoval et al.
J. Clin. Med. 2024, 13(16), 4615; https://doi.org/10.3390/jcm13164615
Full text available online: https://www.mdpi.com/2077-0383/13/16/4615

6. “Flow Diversion for Endovascular Treatment of Intracranial Aneurysms: Past, Present, and Future Directions”
by Michael Gaub, Greg Murtha, Molly Lafuente, Matthew Webb, Anqi Luo, Lee A. Birnbaum, Justin R. Mascitelli and Fadi Al Saiegh
J. Clin. Med. 2024, 13(14), 4167; https://doi.org/10.3390/jcm13144167
Full text available online: https://www.mdpi.com/2077-0383/13/14/4167

7. “A Long-Term Comparative Analysis of Endovascular Coiling and Clipping for Ruptured Cerebral Aneurysms: An Individual Patient-Level Meta-Analysis Assessing Rerupture Rates”
by Johannes Wach, Martin Vychopen, Agi Güresir, Alexandru Guranda, Ulf Nestler and Erdem Güresir
J. Clin. Med. 2024, 13(6), 1778; https://doi.org/10.3390/jcm13061778
Full text available online: https://www.mdpi.com/2077-0383/13/6/1778

8. “Influence of High-Intensity Interval Training on Neuroplasticity Markers in Post-Stroke Patients: Systematic Review”
by Gines Montero-Almagro, Carlos Bernal-Utrera, Noelia Geribaldi-Doldán, Pedro Nunez-Abades, Carmen Castro and Cleofas Rodriguez-Blanco
J. Clin. Med. 2024, 13(7), 1985; https://doi.org/10.3390/jcm13071985
Full text available online: https://www.mdpi.com/2077-0383/13/7/1985

9. “Stroke in Young Adults”
by Syed Bukhari, Shadi Yaghi and Zubair Bashir
J. Clin. Med. 2023, 12(15), 4999; https://doi.org/10.3390/jcm12154999
Full text available online: https://www.mdpi.com/2077-0383/12/15/4999

10. “Age Stratification and Stroke Severity in the Telestroke Network”
by Cassie A. Simmons, Nicolas Poupore and Thomas I. Nathaniel
J. Clin. Med. 2023, 12(4), 1519; https://doi.org/10.3390/jcm12041519
Full text available online: https://www.mdpi.com/2077-0383/12/4/1519

 Special Issues:

Recent Advances in Intracranial Aneurysm Treatment
Guest Editor: Dr. Victor Volovici
Submission deadline: 25 November 2025

Neurovascular Diseases: Clinical Advances and Challenges
Guest Editors: Dr. Roberto Colasanti; Dr. Silky Chotai; Dr. Alessandro Di Rienzo and Dr. Joham Choque-Velasquez
Submission deadline: 25 November 2025

Current Situation and Challenges of Endovascular Treatment Strategies for Acute Ischemic Stroke
Guest Editor: Prof. Dr. Fusao Ikawa
Submission deadline: 20 January 2026

Revolutionizing Neurosurgery: Cutting-Edge Techniques and Innovations
Guest Editor: Dr. Yoichi Morofuji
Submission deadline: 31 January 2026

31 July 2025
MDPI INSIGHTS: The CEO's Letter #25 - 8,000 Staff Worldwide, Korea Visit, 100,000 Preprints, Malaysia Roundtable, Canada Consortium Deal

Welcome to the MDPI Insights: The CEO's Letter.

In these monthly letters, I will showcase two key aspects of our work at MDPI: our commitment to empowering researchers and our determination to facilitating open scientific exchange.


Opening Thoughts

Talent Drives Our Progress

For the first time in MDPI’s history, we now have over 8,000 colleagues across the company. I would like to take a moment to celebrate this milestone and acknowledge the driving force behind our growth and success: our people.

As the world’s leading fully open access publisher, MDPI has grown thanks to the dedication, talent, and teamwork of colleagues across the company. Already halfway through 2025, we’ve welcomed nearly 2,000 new colleagues. 

“Our achievements are also about the people behind them”

We now manage over 475 journals, with 298 receiving an Impact Factor, and hundreds more indexed in major databases, including 343 in Scopus, and 92 by PubMed. As the reach and impact of our journals continues to grow, so does the need for dedicated and qualified teams to support that growth. Thus, attracting and retaining exceptional talent remains a cornerstone of our success.

Our achievements are not just about the results of journal expansion, however: they’re about the people behind them. From our hardworking editors to our meticulous English editing and production teams – from our journal relationship specialists, public relations, marketing and communications professionals to our conference teams and the project teams behind Preprints, Scilit, SciProfiles, JAMS and more. Our success reflects the work of thousands of people showing up each day, taking pride in their work, and committed to excellence and service.

What we’re doing to support talent:

  • Investing in onboarding and training to help new colleagues feel welcomed and empowered to thrive.
  • Creating clearer career paths across all functions, from editorial to communications and beyond.
  • Launching mentorship programs and internal knowledge-sharing sessions to promote growth and collaboration.
  • Evolving our recognition and rewards programs to better celebrate your contributions.
  • Expanding our training systems and platforms.

MDPI’s in-house training department offers over 215 training courses, covering topics from editorial development to cross-cultural collaboration. In 2024 alone, we had 44 full-time trainers and 196 part-time training assistants supporting the learning and development needs of colleagues worldwide. These efforts ensure our teams are equipped with the skills and confidence to grow professionally and contribute meaningfully.

Over two-thirds of our workforce is editorial, and of our more than 5,400 editors, 87% hold a Master’s degree and 6% a PhD. Their collective contributions are central to delivering a high-quality publishing experience and supporting global academic communication.

As we celebrate this milestone, we also aim to continue on a path of steady and sustainable growth, one that balances journal expansion with investment in people, outreach, processes, and innovation. Together, we are shaping the future of open access and academic publishing. Thank you for your hard work, your ideas, and your commitment to serving the global research community.

Let’s continue working together to create a culture where great talent grows and every colleague feels valued.

Impactful Research

Visiting South Korea: Building Connections and Supporting the MDPI Seoul Office

In July, I had the opportunity to visit our team in Seoul and engage directly with academic communities in South Korea. The visit focused on deepening MDPI’s relationships with local universities, institutions, and partners, and supporting the great work of our colleagues at the MDPI Seoul office.

Korea Association of Private University Libraries (KAPUL) Conference

A highlight of the visit was our participation in the Korea Association of Private University Libraries (KAPUL) Conference, where we presented to over 100 academic librarians. I delivered a keynote speech titled “The Evolving Publishing Landscape: Open Access and Beyond,” while my colleague Dr. Jisuk Kang (Public Affairs Specialist) shared insights in her presentation, “Inside MDPI: Editorial Practices & Research Integrity.”

Facts & Figures: South Korea

  • South Korea is MDPI’s sixth-largest publishing country by article volume (over 90,000 MDPI papers published to date).
  • In 2024, Korea ranked 16th globally by total publications, and 6th (among these top 20 countries) by citation impact.
  • 52% of Korean publications in 2024 were OA – and 73% of those were Gold OA.
  • MDPI published about 20% of all OA papers from Korea in 2024.
  • Over 2,000 active Editorial Board Members from South Korea contribute to MDPI journals, with 11 Section Editors-in-Chief.
  • We currently have 11 Institutional Open Access Program agreements and two society partnerships in Korea:
    • Korean Society of Pharmaceutical Sciences and Technology (with MDPI journal Pharmaceutics)
    • Korean Tribology Society (with MDPI journal Coatings)

MDPI Seoul Office and the First Korea Salon

Our Seoul office serves as a regional hub for marketing, communications, and community engagement. It continues to grow in size and influence, prioritizing supporting scholar visits, conference sponsorships, and outreach events such as the recent MDPI Korea Salon.

The inaugural Salon, themed “Exploring Research Trends in Medical Publishing, Ethics, and AI,” brought together over 20 scholars and Editorial Board members serving MDPI journals.

Thank you to our guest speakers including Professors Young-Joon Surh of Seoul National University, Kwang-Sig Lee of Korea University, and Jin-Won Noh of Yonsei University who presented on the landscape of medicine in South Korea and across the globe. The Salon also included presentations from MDPI colleagues on Open Access, ethics, and how the IOAP can support researchers in this field.

“Our Seoul office continues to grow in size and influence”

Looking Ahead

MDPI is already the leading OA publisher in South Korea, yet challenges and misconceptions around OA and APCs remain. Visits like this one, along with the ongoing efforts of our Seoul office, are important to building understanding, trust, and long-term relationships with the local academic community.

A big thank-you to our colleagues in Seoul for their warm hospitality, professionalism, and energy! Our new office is well situated, staffed, and ready to grow. This visit marked an important step forward in our continued mission to support global research communities and advance Open Science.

Inside MDPI

Preprints.org Reaches 100,000 Preprints: A Major Milestone for MDPI and Open Science

In case you missed it, Preprints.org recently surpassed 100,000 preprints posted. This is a major milestone for our platform and one worth celebrating.

Preprints are a key pillar of the Open Science movement, which promotes transparency, equity, and faster knowledge-sharing through initiatives such as Open Access, Open Data, Open Source, and Open Peer Review. The benefits of Open Science extend beyond researchers, as they support funders, educators, policymakers, and the public in advancing discovery and innovation.

What is behind the 100,000 preprints milestone?

Since its launch in 2016, Preprints.org has grown into one of the world’s leading preprint platforms, now ranked fifth globally by publication volume.

More than 350,000 researchers have contributed, helping shape this dynamic and collaborative space for sharing early-stage research across all disciplines.

Read the full announcement here:
https://www.mdpi.com/about/announcements/12202

“Preprints.org has grown into one of the world’s leading preprint platforms”

Some quick facts worth noting:

  • About 56% of the preprints on Preprints.org are later published in peer-reviewed journals.
  • The platform is now indexed in Web of Science (Preprint Citation Index), Europe PMC, and Crossref, helping improve visibility and trust in the preprints shared.
  • Recent upgrades – including a revamped website, new features such as search subscriptions, curated reading lists, and community feedback tools (PREreview) – show our commitment to developing Preprints.org in line with researchers’ needs.

This growth and progress would not be possible without the dedication of the Preprints.org team, our Advisory Board members, screeners, and colleagues across MDPI who support the platform’s development. This milestone is a reminder of our shared mission: to accelerate scientific communication and build a more open, transparent, and inclusive research ecosystem.

I’m excited to see what’s ahead as we approach Preprints.org’s 10-year anniversary in 2026!

Coming Together for Science

Malaysia Media Roundtable: Educating on Open Access and MDPI’s Presence in Southeast Asia

At the end of June, I had the opportunity to participate in a strategic media roundtable in Kuala Lumpur, focused on raising awareness about the importance of Open Access (OA) and on MDPI’s growing presence in Southeast Asia.

We welcomed five Malaysian media outlets for an engaging private session that included presentations and open discussion.

I gave an overview of the benefits of Open Access, MDPI’s global developments, and our collaborations in Malaysia.

My colleague Yu Nwe Soe (Public Relations Specialist), presented on our editorial process, helping to clarify how MDPI supports authors and maintains research quality.

We were also joined by two local Editorial Board Members (EBMs) who offered first-hand insights into their experiences working with MDPI and how OA has shaped their publishing choices.

The discussion covered a range of questions from the press, from OA publishing models to editorial standards, and highlighted MDPI’s unique contribution to accelerating scientific communication in the region.

As the leading fully OA publisher, we see it as our responsibility to continue educating research communities and the broader public on the impact of OA, especially in emerging and high-growth academic markets.

Spotlight on Malaysia

Malaysia continues to rise as a regional research hub, with five universities ranked in the global top 200 and 11 subjects in the global top 50. In 2024, Malaysia ranked 2nd in Southeast Asia in total publication output, 10th in Asia, and 25th globally.

MDPI’s presence in Malaysia:

  • Over 21,000 research articles published to date from Malaysian institutions
  • More than 1,100 articles published in 2024 alone
  • In the period 2020–2024, 54% of Malaysia’s total publications were OA
  • 36 EBMs from Malaysia, across 27 MDPI journals
  • Around 100 conferences sponsored in Malaysia in the past five years
  • MDPI is hosting the 2nd International Conference on AI Sensors and Transducers in Kuala Lumpur (29 July- 3 August 2025)

Media Coverage & Editorial Voices

Following the roundtable, we saw positive coverage across several local outlets, with articles highlighting MDPI’s role in empowering Malaysian researchers. Notable pieces included:

Our local EBMs also shared their perspectives:

Prof. Denny Ng Kok Sum (Sunway University, EBM of MDPI journal Processes) and Prof. Lee (EBM of MDPI journal Bacteria) share their experiences with MDPI and the role Open Access plays in their publication decisions.

“We see it as our responsibility to continue educating research communities on the impact of OA”

“I didn’t want my work stuck behind a paywall.”
— Prof. Denny Ng Kok Sum, Sunway University, Processes Editorial Board Member

“Open Access opens doors for collaboration and visibility, especially in fast-developing regions like ours.”
— Prof. Lee, Bacteria Editorial Board Member

This roundtable marked another step in building trust, understanding, and collaboration in Southeast Asia. A big thank-you to the MDPI Malaysia team and all those who contributed to the event’s success.

Closing Thoughts

MDPI Signs First North American Agreement with Canadian Consortium

We are proud to announce a major milestone for MDPI Canada and an important step forward for OA in North America.

In July, our Toronto office finalized MDPI’s first North American consortium agreement with the Federal Science Libraries Network (FSLN). This is a significant achievement that strengthens our expansion in Canada and reinforces our global commitment to supporting Open Science.

This two-year agreement gives Canadian federal agencies access to MDPI’s IOAP, including discounted article processing charges for affiliated researchers across our portfolio of over 475 OA journals. It lowers barriers for Canadian scientists to share their work more openly and reach a global audience.


Ryan Siu, Institutional Partnerships Manager at MDPI.

“The Open Science landscape in Canada is rapidly evolving, with the Tri-Agency Open Access Policy set for renewal by the end of 2025. This reflects ongoing efforts to foster greater scientific transparency and accessibility at a national policy level,” says Ryan Siu, Institutional Partnerships Manager at MDPI.

“Our new agreement with FSLN represents our shared commitment to further these efforts and foster wider readership. By aligning with these initiatives, we make progress towards research that’s both inclusive and impactful, benefiting local and global communities alike.”

Participating FSLN institutions include:

  • Agriculture and Agri-Food Canada
  • Environment and Climate Change Canada
  • Health Canada
  • National Research Council Canada
  • Natural Resources Canada

By partnering with some of Canada’s largest science-based agencies, we reaffirm our goal of advancing OA across continents. We look forward to developing our support for Canadian researchers and continuing to drive progress in Open Science across North America and beyond.

Stefan Tochev
Chief Executive Officer
MDPI AG

30 July 2025
Meet Us at the United European Gastroenterology Week Berlin 2025, 4–7 October 2025, Berlin, Germany


Conference: United European Gastroenterology Week Berlin 2025

Date: 4–7 October 2025

Location: Berlin, Germany

MDPI will be attending the upcoming United European Gastroenterology Week Berlin 2025 (UEG Week) as an exhibitor. This conference will be held in Berlin, Germany, from 4 to 7 October 2025 and is organized by the United European Gastroenterology.

As one of the largest GI congresses in Europe, UEG Week brings together digestive health experts from around the world to share the latest multidisciplinary research and advancements in gastroenterology.

Topics include the following:

  • Oesophageal, Gastric and Duodenal Diseases;
  • Helicobacter pylori (H. pylori);
  • Small Intestine;
  • Nutrition;
  • Inflammatory Bowel Disease (IBD, including microscopic colitis);
  • Lower gastrointestinal tract (Lower GI, excluding IBD);
  • Liver;
  • Biliary System;
  • Pancreas.

The following MDPI journals will be represented:

If you are attending this conference, please feel free to start an online conversation with us. Our delegates look forward to meeting you in person at booth #4.32 and answering any questions that you may have. For more information about this conference, please visit the following website: https://ueg.eu/week.

30 July 2025
Journal of Clinical Medicine | Title Story Articles for the First Half of 2025


We are delighted to present a list of title story articles selected for display at the top of the homepage of the Journal of Clinical Medicine (JCM, ISSN: 2077-0383) for the first half of 2025. These articles cover a wide range of topics at the heart of the most recent trends in medical research, including heart failure, HPV infection, septic cardiomyopathy, and vasculitis, to name a few. All of these articles can be accessed online by clicking on the appropriate link. We hope that medical practitioners, researchers, and those who are curious about medical knowledge can be inspired by these articles.

  1. “Heart Failure in Older Patients: An Update”
    by Massimo Montalto, Federica D'Ignazio, Sara Camilli, Silvino Di Francesco, Marco Fedele, Francesco Landi and Antonella Gallo
    J. Clin. Med. 2024, 14(6), 1982; https://doi.org/10.3390/jcm14061982
    Full text available online: https://www.mdpi.com/2077-0383/14/6/1982
  2. “HPV Infection in Children and Adolescents—A Comprehensive Review”
    by Paulina Tomecka, Anna Karwowska, Jacek Kuźnicki, Katarzyna Skinderowicz, Aleksandra Wojno, Kornelia Markut, Paulina Typek, Urszula Ciesielska, Julita Kulbacka and Małgorzata Drąg-Zalesińska
    J. Clin. Med. 2024, 14(7), 2425; https://doi.org/10.3390/jcm14072425
    Full text available online: https://www.mdpi.com/2077-0383/14/7/2425
  3. “Perspective on Renal Involvement in Antiphospholipid Syndrome: Implications for Diagnosis, Pathogenesis, and Treatment”
    by Ariela Hoxha, Dorella Del Prete, Irene Condonato, Francesca K. Martino, Marco Lovisotto, Federico Nalesso and Paolo Simioni
    J. Clin. Med. 2024, 14(10), 3326; https://doi.org/10.3390/jcm14103326
    Full text available online: https://www.mdpi.com/2077-0383/14/10/3326
  4. “Attention-Deficit/Hyperactivity Disorder Symptoms Are Common and Associated with Worse Glycemic Control in Adults with Type 1 Diabetes”
    by Yanli Zhang-James, Dan Draytsel, Ben Carguello, Stephen V. Faraone and Ruth S. Weinstock
    J. Clin. Med. 2024, 14(10), 3606; https://doi.org/10.3390/jcm14103606
    Full text available online: https://www.mdpi.com/2077-0383/14/10/3606
  5. “Minimally Invasive Surgery for Spontaneous Intracerebral Hemorrhage: A Review”
    by Nourou Dine Adeniran Bankole, Cyrille Kuntz, Alexia Planty-Bonjour, Quentin Beaufort, Thomas Gaberel, Charlotte Cordonnier, Marco Pasi, Frieder Schlunk, Jawed Nawabi and Ilyess Zemmoura et al.
    J. Clin. Med. 2024, 14(4), 1155; https://doi.org/10.3390/jcm14041155
    Full text available online: http://dx.doi.org/10.3390/jcm14041155
  6. “Septic Cardiomyopathy: Difficult Definition, Challenging Diagnosis, Unclear Treatment”
    by George E. Zakynthinos, Grigorios Giamouzis, Andrew Xanthopoulos, Evangelos Oikonomou, Konstantinos Kalogeras, Nikitas Karavidas, Ilias E. Dimeas, Ioannis Gialamas, Maria Ioanna Gounaridi, Gerasimos Siasos et al.
    J. Clin. Med. 2024, 14(3), 986; https://doi.org/10.3390/jcm14030986
    Full text available online: http://dx.doi.org/10.3390/jcm14030986
  7. “Differential Fatigue Profile in Patients with Post-COVID Condition, Fibromyalgia, and Multiple Sclerosis”
    by Silvia Oliver-Mas, Jordi A. Matias-Guiu, Cristina Delgado-Alonso, Constanza Cuevas, José Manuel Alcalá Ramírez del Puerto, Juan Ignacio López-Carbonero, Jorge Matias-Guiu and Maria Diez-Cirarda
    J. Clin. Med. 2024, 14(3), 952; https://doi.org/10.3390/jcm14030952
    Full text available online: http://dx.doi.org/10.3390/jcm14030952
  8. “Culprit-Lesion Drug-Coated-Balloon Percutaneous Coronary Intervention in Patients Presenting with ST-Elevation Myocardial Infarction (STEMI)”
    by Jorge Sanz-Sánchez, Andrea Teira Calderón, David Neves, Carlos Cortés Villar, Antonela Lukic, Eva Rumiz González, Guillermo Sánchez-Elvira, Lino Patricio, José Luis Díez-Gil, Héctor M. García-García et al.
    J. Clin. Med. 2024, 14(3), 869; https://doi.org/10.3390/jcm14030869
    Full text available online: http://dx.doi.org/10.3390/jcm14030869
  9. “How We Treat ANCA-Associated Vasculitis: A Focus on the Maintenance Therapy”
    by Dario Roccatello, Roberta Fenoglio, Emanuele De Simone and Savino Sciascia
    J. Clin. Med. 2024, 14(1), 208; https://doi.org/10.3390/jcm14010208
    Full text available online: http://dx.doi.org/10.3390/jcm14010208
  10. “Advanced Lung Cancer Inflammation Index as Predictor of All-Cause Mortality in ST-Elevation Myocardial Infarction Patients Undergoing Primary Percutaneous Coronary Intervention”
    by Giancarlo Trimarchi, Fausto Pizzino, Alessio Lilli, Alberto Ranieri De Caterina, Augusto Esposito, Stefano Dalmiani, Annamaria Mazzone, Gianluca Di Bella, Sergio Berti and Umberto Paradossi
    J. Clin. Med. 2023, 13(20), 6059; https://doi.org/10.3390/jcm13206059
    Full text available online: https://www.mdpi.com/2077-0383/13/20/6059
  11. “Kidney Stones of Type I vs. Type II Diabetic Patients: Are There Any Differences?”
    by Cătălin Pricop, Marius Ivănuță, Mihaela Nikolic and Dragoş Puia
    J. Clin. Med. 2023, 13(20), 6110; https://doi.org/10.3390/jcm13206110
    Full text available online: https://www.mdpi.com/2077-0383/13/20/6110
  12. “Hybrid and Endovascular Management of Aortic Arch Pathology”
    by Richard Shi and Mathew Wooster
    J. Clin. Med. 2023, 13(20), 6248; https://doi.org/10.3390/jcm13206248
    Full text available online: https://www.mdpi.com/2077-0383/13/20/6248
  13. “Novel Minimally Invasive Surgical Approaches to Endometriosis and Adenomyosis: A Comprehensive Review”
    by Flávia Ribeiro and Hélder Ferreira
    J. Clin. Med. 2023, 13(22), 6844; https://doi.org/10.3390/jcm13226844
    Full text available online: https://www.mdpi.com/2077-0383/13/22/6844
  14. “Diagnosis and Treatment of Acute Heart Failure: A Retrospective Observational Study and Medical Audit”
    by Justas Suchina, Giorgia Lüthi-Corridori, Fabienne Jaun, Jörg D. Leuppi and Maria Boesing
    J. Clin. Med. 2023, 13(19), 5951; https://doi.org/10.3390/jcm13195951<
    Full text available online: https://www.mdpi.com/2077-0383/13/19/5951
  15. “High-Volume Hemodiafiltration Versus High-Flux Hemodialysis: A Narrative Review for the Clinician”
    by Bernard Canaud, Giovanni Strippoli and Andrew Davenport
    J. Clin. Med. 2024, 14(8), 2614; https://doi.org/10.3390/jcm14082614
    Full text available online: https://www.mdpi.com/2077-0383/14/8/2614

To access more journal information, please click the following link: https://www.mdpi.com/journal/jcm.

JCM Editorial Office

29 July 2025
Meet Us at the 61st Annual Meeting European Association for the Study of Diabetes (EASD 2025), 15–19 September 2025, Vienna, Austria


Conference: 61st Annual Meeting European Association for the Study of Diabetes (EASD 2025)
Date: 15–19 September 2025
Location: Vienna, Austria

MDPI will be attending the 61st Annual Meeting European Association for the Study of Diabetes (EASD 2025), which will be held from 15 to 19 September 2025, as an exhibitor. We welcome researchers from diverse backgrounds to attend and share their latest ideas with us.

The EASD Annual Meeting is an excellent opportunity to stay up to date with recent developments in the diabetes field. The programme features groundbreaking basic research, cutting-edge clinical trial results and in-depth expert debates. We are pleased to attend the conference and also meet with colleagues from around the world and be part of the key discussions that will shape the future of diabetes research and care. Your participation will significantly contribute to the medical discourse and enhance the conference’s impact within the diabetes field.

The following open access journals will be represented at the conference:

  • Biomedicines;
  • Diabetology;
  • JCM;
  • Medicina;
  • IJERPH;
  • Obesities;
  • Nutrients;
  • Biomolecules;
  • LabMed;
  • Lipidology;
  • Metabolites;
  • Endocrines.

If you are planning to attend the above conference, please do not hesitate to start an online conversation with us. Our delegates look forward to meeting you in person at the booth and answering any questions that you may have. For more information about the conference, please visit the following website: https://www.easd.org/annual-meeting/easd-2025.html.

28 July 2025
World Hepatitis Day—“Hepatitis: Let’s Break It Down”, 28 July 2025


World Hepatitis Day is observed each year on 28 July to raise awareness of viral hepatitis, a type of inflammation of the liver that causes severe liver disease and liver cancer.

The theme for 2025—“Hepatitis: Let’s Break It Down”—calls for urgent action to dismantle the financial, social and systemic barriers, including stigma, that stand in the way of hepatitis elimination and liver cancer prevention.

Chronic hepatitis B and C silently cause liver damage and cancer—despite them being preventable, treatable, and, in the case of hepatitis C, curable. The theme emphasizes the need to simplify, scale up, and integrate hepatitis services—vaccination, safe injection practices, harm reduction and especially testing and treatment—into national health systems.

The campaign is a reminder that we must act now to expand access, integrate care, and end hepatitis as a public health problem by 2030.

In recognition of this important day, we recommend the following related articles, Special Issues, and journals spanning multidisciplinary fields, including clinical medicine. We believe that promoting such research contributes to enhanced public awareness and a greater understanding of viral hepatitis, an inflammation of the liver that causes severe liver disease and liver cancer.


Biology & Life Sciences

Medicine & Pharmacology


Curcumin Nanocarriers in the Protection Against Iron- and Alcohol-Induced Oxidative Stress in a Cellular Model of Liver Disease
by Lucy Petagine, Mohammed G. Zariwala, Satyanarayana Somavarapu, Stefanie Ho Yi Chan and Vinood B. Patel
Biology 2025, 14(5), 455; https://doi.org/10.3390/biology14050455

Hepatic Estrogen Receptor Alpha Overexpression Protects Against Hepatic Insulin Resistance and MASLD
by Ester S. Alves, Jessica D. M. Santos, Alessandra G. Cruz, Felipe N. Camargo, Carlos H. Z. Talarico, Anne R. M. Santos, Carlos A. A. Silva, Henrique J. N. Morgan, Sandro L. Matos, Layanne C. C. Araujo et al.
Pathophysiology 2025, 32(1), 1; https://doi.org/10.3390/pathophysiology32010001

Change in Estimated Glomerular Filtration Rate After Direct-Acting Antiviral Treatment in Chronic Hepatitis C Patients
by Gantogtokh Dashjamts, Amin-Erdene Ganzorig, Yumchinsuren Tsedendorj, Dolgion Daramjav, Enkhmend Khayankhyarvaa, Bolor Ulziitsogt, Otgongerel Nergui, Ganchimeg Dondov, Tegshjargal Badamjav, Tulgaa Lonjid et al.
Diseases 2025, 13(2), 26; https://doi.org/10.3390/diseases13020026

Effects of SARS-CoV-2 Spike S1 Subunit on the Interplay Between Hepatitis B and Hepatocellular Carcinoma Related Molecular Processes in Human Liver
by Giovanni Colonna
Livers 2025, 5(1), 1; https://doi.org/10.3390/livers5010001

Liver Cancer Neuroscience: Regulating Liver Tumors via Selective Hepatic Vagotomy
by Kylynda C. Bauer, Shadin Ghabra, Chi Ma Lee Chedester and Tim F. Greten
Methods Protoc. 2024, 7(6), 99; https://doi.org/10.3390/mps7060099

Role of Circulating microRNAs in Liver Disease and HCC: Focus on miR-122
by Francesco Colaianni, Veronica Zelli, Chiara Compagnoni, Martina Sara Miscione, Mario Rossi, Davide Vecchiotti, Monica Di Padova, Edoardo Alesse, Francesca Zazzeroni and Alessandra Tessitore
Genes 2024, 15(10), 1313; https://doi.org/10.3390/genes15101313

Impact of Hepatitis Delta Virus Infection on the Selection of Hepatitis B Surface Antigen Mutations
by Kabo Baruti,Wonderful T. Choga, Bonolo B. Phinius, Basetsana Phakedi, Lynnette Bhebhe, Gorata G. A. Mpebe, Patience C. Motshosi, Tsholofelo Ratsoma, Sikhulile Moyo, Mosimanegape Jongman et al.
Genes 2024, 15(8), 982; https://doi.org/10.3390/genes15080982

NAFLD/MASLD and the Gut–Liver Axis: From Pathogenesis to Treatment Options
by Natalia G. Vallianou, Dimitris Kounatidis, Sotiria Psallida, Nikolaos Vythoulkas-Biotis, Andreas Adamou, Tatiana Zachariadou, Sofia Kargioti, Irene Karampela and Maria Dalamaga
Metabolites 2024, 14(7), 366; https://doi.org/10.3390/metabo14070366

miRNA Expression and HCC Occurrence in HCV Cirrhotic Patients Treated with Direct Acting Antivirals
by Antonietta Romano, Alessandra Brocca, Zoe Mariño, Sofía Pérez-del-Pulgar, Sabela Lens, Loreto Boix, María Reig, Jordi Bruix, Giulio Ceolotto, Valeria Calvino et al.
Livers 2024, 4(2), 275-286; https://doi.org/10.3390/livers4020020

The Full-Genome Analysis and Generation of an Infectious cDNA Clone of a Genotype 6 Hepatitis E Virus Variant Obtained from a Japanese Wild Boar: In Vitro Cultivation in Human Cell Lines
by Putu Prathiwi Primadharsini, Masaharu Takahashi, Tsutomu Nishizawa, Yukihiro Sato, Shigeo Nagashima, Kazumoto Murata and Hiroaki Okamoto
Viruses 2024, 16(6), 842; https://doi.org/10.3390/v16060842

Hepatitis C Prevalence and Birth Outcomes among Pregnant Women in the United States: A 2010–2020 Population Study
by Paul Wasuwanich, Songyos Rajborirug, Robert S. Egerman, Tony S. Wen and Wikrom Karnsakul
Pathogens 2024, 13(4), 321; https://doi.org/10.3390/pathogens13040321

Prospects for Controlling Hepatitis B Globally
by Vicente Soriano, Víctor Moreno-Torres, Ana Treviño, Fernando de Jesús, Octavio Corral and Carmen de Mendoza
Pathogens 2024, 13(4), 291; https://doi.org/10.3390/pathogens13040291

Longterm Outcome of Therapeutic Vaccination with a Third Generation Pre-S/S HBV Vaccine (PreHevbrioR) of Chronically HBV Infected Patients
by Hedwig Roggendorf, Daniel Shouval, Michael Roggendorf and Guido Gerken
J. Pers. Med. 2024, 14(4), 364; https://doi.org/10.3390/jpm14040364

NAFLD Fibrosis Progression and Type 2 Diabetes: The Hepatic–Metabolic Interplay
by Simona Cernea
Life 2024, 14(2), 272; https://doi.org/10.3390/life14020272

Updated Clinical Guidelines on the Management of Hepatitis C Infection in Children
by Chaowapong Jarasvaraparn, Christopher Hartley and Wikrom Karnsakul
Pathogens 2024, 13(2), 180; https://doi.org/10.3390/pathogens13020180

Non-Invasive Assessment of Liver Fibrosis in Hepatitis B Patients
by Chinmay Bera, Nashla Hamdan-Perez and Keyur Patel
J. Clin. Med. 2024, 13(4), 1046; https://doi.org/10.3390/jcm13041046

Real-World Utilization of Corticosteroids in Severe Alcoholic Hepatitis: Eligibility, Response, and Outcomes
by Ana-Maria Singeap, Horia Minea, Oana Petrea, Madalina-Andreea Robea, Ioana-Miruna Balmuș, Raluca Duta, Ovidiu-Dumitru Ilie, Carmen Diana Cimpoesu, Carol Stanciu and Anca Trifan
Medicina 2024, 60(2), 311; https://doi.org/10.3390/medicina60020311

Autoimmune Hepatitis: A Diagnostic and Therapeutic Overview
by Lydia A. Mercado, Fernando Gil-Lopez, Razvan M. Chirila and Denise M. Harnois
Diagnostics 2024, 14(4), 382; https://doi.org/10.3390/diagnostics14040382

Hepatoprotective Effects of Flavonoids against Benzo[a]Pyrene-Induced Oxidative Liver Damage along Its Metabolic Pathways
by Min Kim, Seung-Cheol Jee and Jung-Suk Sung
Antioxidants 2024, 13(2), 180; https://doi.org/10.3390/antiox13020180

Enhancing Liver Delivery of Gold Nanoclusters via Human Serum Albumin Encapsulation for Autoimmune Hepatitis Alleviation
by Cong Meng, Yu Liu, Yuping Ming, Cao Lu, Yanggege Li, Yulu Zhang, Dongdong Su, Xueyun Gao and Qing Yuan
Pharmaceutics 2024, 16(1), 110; https://doi.org/10.3390/pharmaceutics16010110

Hepatitis B Virus Reactivation with Immunosuppression: A Hidden Threat?
by Sama Anvari and Keith Tsoi
J. Clin. Med. 2024, 13(2), 393; https://doi.org/10.3390/jcm13020393

Metabolic Dysfunction-Associated Fatty Liver Disease and Chronic Viral Hepatitis: The Interlink
by Cornelius J. Fernandez, Mohammed Alkhalifah, Hafsa Afsar and Joseph M. Pappachan
Pathogens 2024, 13(1), 68; https://doi.org/10.3390/pathogens13010068

A Case Report: Idiopathic or Drug-Induced Autoimmune Hepatitis—Can We Draw a Line?
by Dorotea Božić, Ante Tonkić, Jr,Katarina Vukojevic and Maja Radman
Clin. Pract. 2023, 13(6), 1393–1399; https://doi.org/10.3390/clinpract13060125

Liver dECM–Gelatin Composite Bioink for Precise 3D Printing of Highly Functional Liver Tissues
by Min Kyeong Kim, Wonwoo Jeong and Hyun-Wook Kang
J. Funct. Biomater. 2023, 14(8), 417; https://doi.org/10.3390/jfb14080417

Viral Hepatitis: Diagnosis, Treatment and Management”
Guest Editors: Dr. Veysel Tahan and Dr. Resat Ozaras
Submission deadline: 31 August 2025

New Insights into Diagnosis and Therapeutic Strategies for Chronic Liver Diseases”
Guest Editor: Prof. Dr. Cristina Marginean
Submission deadline: 20 October 2025

“The Surveillance, Prevention, and Treatment of Viral Hepatitis: Looking Forward to Global Elimination”
Guest Editor: Dr. Melanie Deutsch
Submission deadline: 31 October 2025

“Viral Hepatitis and Therapeutic Strategies
Guest Editor: Dr. Arshi Khanam
Submission deadline: 20 November 2025

“Genetic Analysis of Hepatitis Virus Infection”
Guest Editors: Prof. Dr. Dan Florin Mihǎilescu and Dr. Maria Alexandra Mernea
Submission deadline: 20 November 2025

“Oxidative Stress in Hepatic Diseases”
Guest Editor: Dr. Miquel Mulero
Submission deadline: 21 November 2025

“Viral Hepatitis Among Specific Populations: Epidemiology, Transmission, Treatment, and Prevention”
Guest Editor: Dr. Aldemir B. Oliveira-Filho
Submission deadline: 15 December 2025

Biology of Liver Diseases
Guest Editors: Dr. Tadashi Namisaki and Dr. Hiroaki Takaya
Submission deadline: 20 December 2025

Hepatitis E Virus (HEV) Infection Among Humans and Animals: Epidemiology, Clinical Characteristics, Treatment and Prevention—2nd Edition
Guest Editors: Dr. Jelena Prpić and Dr. Magdalena Baymakova
Submission deadline: 31 December 2025

“Human Hepatitis Viruses and Their Animal Homologues”
Guest Editors: Dr. Bo Wang and Prof. Dr. Xinglou Yang
Submission deadline: 31 December 2025

Advances in Hepatitis: Prevention, Treatment, and Global Health Impact
Guest Editors: Dr. Michał Brzdęk, Prof. Dr. Dorota Zarębska-Michaluk and Dr. Krystyna Dobrowolska
Submission deadline: 28 January 2026

“Pathogenesis of Viral Hepatitis”
Guest Editor: Dr. Po-Yuan Ke
Submission deadline: 28 February 2026

Liver Diseases: Diagnosis and Treatment in the Era of Personalized Medicine
Guest Editors: Dr. María Teresa Arias-Loste and Dr. Armando Raúl Guerra-RuizSubmission deadline: 30
April 2026

“Gastrointestinal and Liver Diseases: New Advances in Diagnosis and Prognosis”
Guest Editor: Prof. Dr. Carmen Fierbinteanu-Braticevici
Submission deadline: closed (31 December 2023)

28 July 2025
Journal of Clinical Medicine Editor of Distinction Award—Winners Announced

The editorial team of Journal of Clinical Medicine (JCM, ISSN: 2077-0383) would like to congratulate the winners of the JCM 2024 Editor of Distinction Award, who were chosen by a selection committee chaired by the Editors-in-Chief, Prof. Dr. Emmanuel Andrès and Prof. Dr. Kent Doi. Following a formal review process by the Award Evaluation Committee, six Editorial Board Members were selected as winners. The recipients are as follows:

Name: Prof. Dr. Teruhiko Imamura
Affiliation: Second Department of Internal Medicine, University of Toyama, Toyama 9300194, Japan
Interests: heart failure; heart transplantation; cardiology; cardiothoracic surgery

Name: Prof. Dr. Andrzej Grzybowski
Affiliation: Foundation for Ophthalmology Development, Poznan, Poland
Interests: AI in ophthalmology; myopia prevention and treatment; cataract and refractive surgery; retina

Name: Prof. Dr. Makoto Inoue
Affiliation: Department of Ophthalmology, Kyorin University School of Medicine, 6-20-2, Shinkawa, Mitaka, Tokyo 181-8611, Japan
Interests: vitreoretinal diseases; vitreoretinal surgery; vitrectomy; macular edema; retinal detachment

Name: Prof. Dr. Etsuo Chihara
Affiliation: Sensho-kai Eye Institute, Uji 611-0043, Kyoto, Japan
Interests: glaucoma surgery; glaucoma imaging; minimally invasive glaucoma surgery (MIGS)

Name: Prof. Dr. Andrew Day
Affiliation: Department of Paediatrics, Christchurch Hospital, University of Otago, Christchurch 4710, New Zealand
Interests: inflammatory bowel disease; coeliac disease; improving Crohn’s outcomes; intestinal inflammatory biomarkers; nutritional aspects of gut diseases; host–pathogen interactions in the gut (and how these relate to chronic gut diseases)

Name: Prof. Dr. Indre Bileviciute-Ljungar
Affiliations: 1Department of Clinical Sciences, Karolinska Institute, Danderyd University Hospital, 18288 Stockholm, Sweden; 2Multidisciplinary Pain Clinic, Capio St. Göran Hospital, 11219 Stockholm, Sweden; 3Department of Physical and Rehabilitation Medicine, Danderyd University Hospital, 18288 Stockholm, Sweden
Interests: fatigue; chronic pain; disability; myalgic encephalomyelitis/chronic fatigue syndrome; COVID-19

You can find more information about this award and how to nominate individuals here: https://www.mdpi.com/journal/jcm/awards. To request further information, please contact the JCM Editorial Office.

Journal of Clinical Medicine Editorial Office

24 July 2025
Journal of Clinical Medicine | Most Downloaded Papers in 2025


Journal of Clinical Medicine (JCM, ISSN: 2077-0383) is an open access journal, with an Impact Factor of 2.9 (2024) and 5-Year Impact Factor of 3.3 (2024), which continues to contribute to the widespread dissemination of medical research with professionalism and reliability. In the first half of 2025, the papers published by JCM have garnered significant popularity with many readers. Here, we have selected 15 high-impact papers with a high average number of downloads to form the following selected collection of recommendations. These research results cover cardiovascular disease, heart failure, diabetes, spinal trauma, hemodialysis, neurodegenerative diseases, spondyloarthritis, cervical spine disease, cardiorenal syndrome, knee replacement, pancreatic tumors, pituitary tumors, inflammatory bowel disease, cancer, and other fields. We hope this will inspire your own research.

You can find the latest research through this link: https://www.mdpi.com/search?q=&journal=jcm&sort=pubdate&page_count=50.

1. “Now and the Future: Medications Changing the Landscape of Cardiovascular Disease and Heart Failure Management
by Thomas Oswald, Steven Coombs, Susan Ellery and Alexander Liu
J. Clin. Med. 2025, 14(11), 3948; https://doi.org/10.3390/jcm14113948
Full text available online: https://www.mdpi.com/2077-0383/14/11/3948

2. “The Relationship of the Plasma Glycated CD59 Level with Microvascular Complications in Diabetic Patients and Its Evaluation as a Predictive Marker
by Ozgur Yilmaz, Osman Erinc, Ayca Gul Gungordu, Mehmet Erdogan, Murvet Algemi and Murat Akarsu
J. Clin. Med. 2025, 14(13), 4588; https://doi.org/10.3390/jcm14134588
Full text available online: https://www.mdpi.com/2077-0383/14/13/4588

3. “Minimally Invasive Lateral Thoracic and Lumbar Interbody Fusion with Expandable Interbody Spacers for Spine Trauma—Indications, Complications and Outcomes
by Linda Bättig, Gregor Fischer, Benjamin Martens, Anand Veeravagu, Lorenzo Bertulli and Martin N. Stienen
J. Clin. Med. 2025, 14(13), 4557; https://doi.org/10.3390/jcm14134557
Full text available online: https://www.mdpi.com/2077-0383/14/13/4557

4. “Hemodynamic Adaptation and Cardiac Effects of High-Flow Arteriovenous Access in Hemodialysis Patients: A Prospective Study
by Yaeni Kim, Ji-hye Kim, Juyeon Woo, Oknan Choi, Mina Lee and Sunryoung Choi
J. Clin. Med. 2025, 14(13), 4556; https://doi.org/10.3390/jcm14134556
Full text available online: https://www.mdpi.com/2077-0383/14/13/4556

5. “Visualization of the Glymphatic System Through Brain Magnetic Resonance in Human Subjects with Neurodegenerative Disorders: A Systematic Review and Meta-Analysis
by Jana Hamzeh, Hayat Harati, Farah Ayoubi, Marie-belle Saab, Lea Saab, Elie Al Ahmar and Elias Estephan
J. Clin. Med. 2025, 14(12), 4387; https://doi.org/10.3390/jcm14124387
Full text available online: https://www.mdpi.com/2077-0383/14/12/4387

6. “Prevalence of Undiagnosed Inflammatory Bowel Disease in Spondyloarthritis Patients
by Jesús Sanz-Sanz, Ana Gutiérrez-Casbas, Zulema Plaza, Jordi Gratacós, Iago Rodríguez-Lago, Ignacio Marín-Jiménez, Elisa Trujillo-Martín, Eva Pérez-Pampín, Manuel Barreiro-de Acosta, María Vanesa Hernández-Hernández et al.
J. Clin. Med. 2025, 14(13), 4569; https://doi.org/10.3390/jcm14134569
Full text available online: https://www.mdpi.com/2077-0383/14/13/4569

7. “Effects of Pre-Operative HbA1c on Outcomes and the Rate of Clinical Improvement Following Anterior Cervical Discectomy and Fusion
by Ara Khoylyan, Noah Coleman, Matthew Parry, Alex Tang and Tan Chen
J. Clin. Med. 2025, 14(13), 4589; https://doi.org/10.3390/jcm14134589
Full text available online: https://www.mdpi.com/2077-0383/14/13/4589

8. “A Pragmatic Approach to Acute Cardiorenal Syndrome: Diagnostic Strategies and Targeted Therapies to Overcome Diuretic Resistance
by Patrick Tran, Laith Khweir, Michael Kuehl, Mithilesh Joshi, Krishna Appunu, Waqar Ayub and Prithwish Banerjee
J. Clin. Med. 2025, 14(9), 2996; https://doi.org/10.3390/jcm14092996
Full text available online: https://www.mdpi.com/2077-0383/14/9/2996

9. “The Temporal–Spatial Parameters of Gait After Total Knee Arthroplasty
by Karina Szczypiór-Piasecka, Paulina Adamczewska, Łukasz Kołodziej and Paweł Ziętek
J. Clin. Med. 2025, 14(13), 4548; https://doi.org/10.3390/jcm14134548
Full text available online: https://www.mdpi.com/2077-0383/14/13/4548

10. “Clinical Features of Intraductal Papillary Mucinous Neoplasm-Related Pancreatic Carcinomas in Long-Term Surveillance
by Kyohei Matsuura, Shinsaku Nagamatsu, Shoma Kikukawa, Yuya Nishio, Yusuke Komeda, Yuya Matsuo, Kohei Ohta, Chisa Yamamoto, Ayana Sueki and Kei Moriya
J. Clin. Med. 2025, 14(13), 4585; https://doi.org/10.3390/jcm14134585
Full text available online: https://www.mdpi.com/2077-0383/14/13/4585

11. “Eye Selection Criteria’s Influence in the Value of Pituitary Macroadenoma Management Biomarkers: Preliminary Findings
by Odelaisys Hernández-Echevarría, Elizabeth Bárbara Cuétara-Lugo, Mario Jesús Pérez-Benítez, Lídice Galán-García, Ibrain Piloto-Diaz and Eduardo Fernández
J. Clin. Med. 2025, 14(13), 4542; https://doi.org/10.3390/jcm14134542
Full text available online: https://www.mdpi.com/2077-0383/14/13/4542

12. “Assessing ChatGPT-v4 for Guideline-Concordant Inflammatory Bowel Disease: Accuracy, Completeness, and Temporal Drift
by Oguz Ozturk, Mucahit Ergul, Yavuz Cagir, Ali Atay, Kadir Can Acun, Orhan Coskun, Ilyas Tenlik, Muhammed Bahaddin Durak and Ilhami Yuksel
J. Clin. Med. 2025, 14(13), 4599; https://doi.org/10.3390/jcm14134599
Full text available online: https://www.mdpi.com/2077-0383/14/13/4599

13. “Risk Factors and Prevention of Cancer and CVDs: A Chicken and Egg Situation
by Maurizio Giuseppe Abrignani, Fabiana Lucà, Vincenzo Abrignani, Mariacarmela Nucara, Daniele Grosseto, Chiara Lestuzzi, Marinella Mistrangelo, Bruno Passaretti, Carmelo Massimiliano Rao and Iris Parrini
J. Clin. Med. 2025, 14(9), 3083; https://doi.org/10.3390/jcm14093083
Full text available online: https://www.mdpi.com/2077-0383/14/9/3083

14. “Cardiovascular–Kidney–Metabolic Syndrome: A New Paradigm in Clinical Medicine or Going Back to Basics?
by Victoria Mutruc, Cristina Bologa, Victorița Șorodoc, Alexandr Ceasovschih, Bianca Codrina Morărașu, Laurențiu Șorodoc, Oana Elena Catar and Cătălina Lionte
J. Clin. Med. 2025, 14(8), 2833; https://doi.org/10.3390/jcm14082833
Full text available online: https://www.mdpi.com/2077-0383/14/8/2833

15. “Endoscopic-Ultrasound-Guided Radiofrequency Ablation for Pancreatic Tumors
by Chiara Coluccio, Stefania Cappetta, Giovanna Romagnoli, Valentina Di Giorgio, Paolo Giuffrida, Stefano Fabbri, Carlo Fabbri and Cecilia Binda
J. Clin. Med. 2025, 14(2), 495; https://doi.org/10.3390/jcm14020495
Full text available online: https://www.mdpi.com/2077-0383/14/2/495

18 July 2025
Journal of Clinical Medicine Indexed in the Reaxys Database


Journal of Clinical Medicine
(JCM, ISSN: 2077-0383) has been indexed in the Reaxys database, which indicates that its academic influence is highly recognized and highlights the great value of the integration of clinical medicine and chemistry. A large number of clinical research results published by JCM provide real-world demand and feedback for disease treatment for researchers in the field of chemistry. After being included in the Reaxys database, these clinical data will be deeply integrated with chemical data.

Core highlights:

  • Accelerating the research and development of new drugs
    Clinical research results can help researchers quickly locate disease targets, screen lead compounds and shorten the drug development cycle;
  • Optimizing clinical decision-making and individualized treatment
    The cross-analysis of clinical data, physicochemical properties, and toxicological characteristics of chemicals provides data support for the optimization of clinical trial scheme and individualized treatment based on molecular characteristics;
  • Deepening the research on the molecular mechanism of diseases
    By integrating clinical observation data with the analysis of chemical structure–activity relationship, it will promote the analysis of disease pathogenesis at the molecular level and help the development of innovative treatment strategies;
  • The promotion of academic influence and the win-win situation of resource integration
    With the global exposure of the paper on Reaxys platform, it will build a high-speed communication channel for the advancement of journal impact factors and the promotion of scholars’ international academic popularity.
    An additional benefit is realizing the efficient linkage of clinical medicine, pharmacy, and chemistry resources, and providing a broader platform for chemical and medical practitioners.

For more details on the journal and its indexing information, please visit the official website:
https://www.mdpi.com/journal/jcm/indexing.

We look forward to your continuous attention and joint exploration of the infinite possibilities of the integration of medicine and chemistry.

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