Announcements

The complexity of asthma as a chronic respiratory disease makes achieving a cure challenging, but medical researchers are continuously exploring new avenues for treatment. We invite you to explore the esteemed collection of highly cited articles on asthma that have been published in Journal of Clinical Medicine (JCM, ISSN: 2077-0383) over the past two years, and we hope that they can provide you with new insights. We are currently accepting submissions for Special Issues focusing on asthma, and we look forward to your contributions.

1. “A Real-World Study of Achievement Rate and Predictive Factors of Clinical and Deep Remission to Biologics in Patients with Severe Asthma”
by Keiji Oishi, Kazuki Hamada, Yoriyuki Murata, Kazuki Matsuda, Syuichiro Ohata, Yoshikazu Yamaji, Maki Asami-Noyama, Nobutaka Edakuni, Tomoyuki Kakugawa, Tsunahiko Hirano et al.
J. Clin. Med. 2023, 12(8), 2900; https://doi.org/10.3390/jcm12082900
Full text available online: https://www.mdpi.com/2077-0383/12/8/2900

2. “Pathobiology of Type 2 Inflammation in Asthma and Nasal Polyposis”
by Corrado Pelaia, Giulia Pelaia, Angelantonio Maglio, Caterina Tinello, Luca Gallelli, Nicola Lombardo, Rosa Terracciano and Alessandro Vatrella
J. Clin. Med. 2023, 12(10), 3371; https://doi.org/10.3390/jcm12103371
Full text available online: https://www.mdpi.com/2077-0383/12/10/3371

3. “Unlocking the Long-Term Effectiveness of Benralizumab in Severe Eosinophilic Asthma: A Three-Year Real-Life Study”
by Laura Diego Bagnasco Pini, Bianca Beghè, Fulvio Braido, Paolo Cameli, Marco Caminati, Cristiano Caruso, Claudia Crimi, Gabriella Guarnieri, Manuela Latorre et al.
J. Clin. Med. 2024, 13(10), 3013; https://doi.org/10.3390/jcm13103013
Full text available online: https://www.mdpi.com/2077-0383/13/10/3013

4. “Severe Asthma and Biological Therapies: Now and the Future”
by Olaia Sardon-Prado, Carolina Diaz-Garcia, Paula Corcuera-Elosegui, Javier Korta-Murua, Jose Valverde-Molina and Manuel Sanchez-Solis
J. Clin. Med. 2023, 12(18), 5846; https://doi.org/10.3390/jcm12185846
Full text available online: https://www.mdpi.com/2077-0383/12/18/5846

5. “Reliability of Total Serum IgE Levels to Define Type 2 High and Low Asthma Phenotypes
by Giuseppe Guida, Francesca Bertolini, Vitina Carriero, Stefano Levra, Andrea Elio Sprio, Martina Sciolla, Giulia Orpheu, Elisa Arrigo, Stefano Pizzimenti, Giorgio Ciprandi et al.
J. Clin. Med. 2023, 12(17), 5447; https://doi.org/10.3390/jcm12175447
Full text available online: https://www.mdpi.com/2077-0383/12/17/5447

6. “Asthma Phenotypes in the Era of Personalized Medicine”
by Victor Gonzalez-Uribe, Sergio J. Romero-Tapia and Jose A. Castro-Rodriguez
J. Clin. Med. 2023, 12(19), 6207; https://doi.org/10.3390/jcm12196207
Full text available online: https://www.mdpi.com/2077-0383/12/19/6207

7. “Managing Small Airway Disease in Patients with Severe Asthma: Transitioning from the “Silent Zone” to Achieving “Quiet Asthma””
by Giovanna Elisiana Carpagnano, Andrea Portacci, Silvano Dragonieri, Francesca Montagnolo, Ilaria Iorillo, Ernesto Lulaj, Leonardo Maselli, Enrico Buonamico and Vitaliano Nicola Quaranta
J. Clin. Med. 2024, 13(8), 2320; https://doi.org/10.3390/jcm13082320
Full text available online: https://www.mdpi.com/2077-0383/13/8/2320

8. “Baseline Characteristics of Patients Enrolled in Clinical Trials of Biologics for Severe Asthma as Potential Predictors of Outcomes”
by Francesco Menzella
J. Clin. Med. 2023, 12(4), 1546; https://doi.org/10.3390/jcm12041546
Full text available online: https://www.mdpi.com/2077-0383/12/4/1546

9. “Switching to Dupilumab from Other Biologics without a Treatment Interval in Patients with Severe Asthma: A Multi-Center Retrospective Study”
by Hisao Higo, Hirohisa Ichikawa, Yukako Arakawa, Yoshihiro Mori, Junko Itano, Akihiko Taniguchi, Satoru Senoo, Goro Kimura, Yasushi Tanimoto, Kohei Miyake et al.
J. Clin. Med. 2023, 12(16), 5174; https://doi.org/10.3390/jcm12165174
Full text available online: https://www.mdpi.com/2077-0383/12/16/5174

10. “Effectiveness of Benralizumab in OCS-Dependent Severe Asthma: The Impact of 2 Years of Therapy in a Real-Life Setting”
by Carolina Vitale, Angelantonio Maglio, Corrado Pelaia, Maria D’Amato, Luigi Ciampo, Giulia Pelaia, Antonio Molino and Alessandro Vatrella
J. Clin. Med. 2023, 12(3), 985; https://doi.org/10.3390/jcm12030985
Full text available online: https://www.mdpi.com/2077-0383/12/3/985

Special Issues
“Advances in Allergic Diseases and Asthma: Clinical Insights and Emerging Therapies” Guest Editor: Prof. Dr. Zenon Brzoza Submission deadline: 20 October 2025	“Respiratory Medicine in the Oldest-Old” Guest Editor: Dr. Takae Ebihara Submission deadline: 25 October 2025
“New Clinical Advances in Pediatric Asthma” Guest Editor: Prof. Dr. Davor Plavec Submission deadline: 15 December 2025	“Advances in Pulmonary Disease Management and Innovation in Treatment” Guest Editors: Dr. Monica Steluța Marc and Prof. Dr. Florin Mihaltan Submission deadline: 15 January 2026

We are pleased to announce that the Journal of Clinical Medicine (JCM, ISSN: 2077-0383) will be granting a Travel Award to two junior scientists for the year 2026. The applications will be assessed by an Evaluation Committee consisting of senior scholars from the JCM Editorial Board. 

This award provides financial support for the winners to attend an international conference in the field of clinical medicine to be held in 2026, in order to hold a presentation, present a poster, or both.

Candidate requirements:

• Postdoctoral fellows or Ph.D. students;
• Plans to attend an international conference in 2026 (oral presentation or poster). 

Required application documents:

• Information about the conference the applicant is planning to attend and the abstract that will be submitted;
• Curriculum vitae and list of publications;
• Justification letter describing the focus of the research (max. 800 words);
• Letter of recommendation from the supervisor, research director, or department head, which also confirms the applicant’s status as a postdoctoral fellow/Ph.D. student.

The winners (two awardees) will each be awarded CHF 800 and an electronic certificate. 

Please submit your applications for the JCM 2026 Travel Award online by 31 December 2025. Prizes will be awarded at the end of January 2026 and announced on the JCM website.

You can find more information about this award and how to nominate here. To request further information, please contact the JCM Editorial Office.

Journal of Clinical Medicine Editorial Office

On 14 June, the world celebrates World Blood Donor Day, a global tribute to the millions of voluntary, unpaid blood donors who give others a second chance at life. Their generosity saves lives, strengthens communities and embodies the spirit of solidarity. It is a day to say thank you, but also to spotlight the ongoing, urgent need for safe, regular blood donations.

The theme of the 2025 World Blood Donor Day is “Give blood, give hope: together we save lives” and the objectives of the campaign are to raise public awareness about the critical need for blood and plasma donations and the impact they have on patients' lives; encourage both new and existing donors to give blood regularly, helping to ensure a stable and sufficient blood supply; highlight the positive impact of blood donors on the health and well-being of others and promote the values of solidarity, compassion, and community through blood donation; and mobilize support from governments and development partners to invest in and sustain national blood programs to achieve universal access to safe blood transfusion worldwide.

In recognition of this important day, we recommend the following related articles, Special Issues, and journals spanning multidisciplinary fields, including clinical medicine. We believe that promoting such research contributes to enhanced public awareness of blood safety and selfless dedication.

“Sickle Cell Anemia and Inflammation: A Review of Stones and Landmarks Paving the Road in the Last 25 Years”
by Jessica Dorneles, Amanda de Menezes Mayer and José Artur Bogo Chies
Hematol. Rep. 2025, 17(1), 2; https://doi.org/10.3390/hematolrep17010002

“Patterns of Blood Transfusion in Sickle Cell Disease Hospitalizations”
by Aditi Sharma, Amit Dahiya, Asif Alavi, Indryas Woldie, Aditya Sharma, Jeffrey Karson and Vijendra Singh
Hemato 2024, 5(1), 26-34; https://doi.org/10.3390/hemato5010004

“Emerging Role of [¹⁸F]FLT PET/CT in Lymphoid Malignancies: A Review of Clinical Results”
by Anna Giulia Nappi, Giulia Santo, Lorenzo Jonghi-Lavarini, Alberto Miceli, Achille Lazzarato, Flavia La Torre, Francesco Dondi and Joana Gorica
Hematol. Rep. 2024, 16(1), 32-41; https://doi.org/10.3390/hematolrep16010004

“Understanding the Intricacies of Iron Overload Associated with β-Thalassemia: A Comprehensive Review”
by Subhangi Basu, Motiur Rahaman, Tuphan Kanti Dolai, Praphulla Chandra Shukla and
Nishant Chakravorty
Thalass. Rep. 2023, 13(3), 179-194; https://doi.org/10.3390/thalassrep13030017

“Bone Marrow Transplantation in Nonmalignant Haematological Diseases: What Have We Learned about Thalassemia?”
by Luca Castagna, Stefania Tringali, Giuseppe Sapienza, Roberto Bono, Rosario Di Maggio and Aurelio Maggio
Thalass. Rep. 2023, 13(2), 122-130; https://doi.org/10.3390/thalassrep13020011

“CRISPR Gene Therapy: A Promising One-Time Therapeutic Approach for Transfusion-Dependent β-Thalassemia—CRISPR-Cas9 Gene Editing for β-Thalassemia”
by Udani Gamage, Kesari Warnakulasuriya, Sonali Hansika and Gayathri N. Silva
Thalass. Rep. 2023, 13(1), 51-69; https://doi.org/10.3390/thalassrep13010006

“Cardiovascular Complications in β-Thalassemia: Getting to the Heart of It”
by Nathalie Akiki, Mohammad H. Hodroj, Rayan Bou-Fakhredin, Kamal Matli and Ali T. Taher
Thalass. Rep. 2023, 13(1), 38-50; https://doi.org/10.3390/thalassrep13010005

“Ferritin Trajectories over Repeated Whole Blood Donations: Results from the FIND+ Study”
by Sara Moazzen, Maike G. Sweegers, Mart Janssen, Boris M. Hogema, Trynke Hoekstra and Katja Van den Hurk
J. Clin. Med. 2022, 11(13), 3581; https://doi.org/10.3390/jcm11133581

“Should We Stop Collecting the Preoperative Autologous Blood before Bone Marrow Harvest?”
by Daniel Lysák, Lenka Hejretová, Marcela Hrabětová and Pavel Jindra
J. Clin. Med. 2021, 10(10), 2134; https://doi.org/10.3390/jcm10102134

“Anaemia in Focus: Challenges and Solutions in Haematology” Guest Editor: Dr. Efthymia Vlachaki Submission deadline: 31 October 2025	“Modern Blood Banking and Transfusion in Clinical Practice: Second Edition” Guest Editor: Dr. Pilar Solves Submission deadline: 25 November 2025
“Hematopathology: Rare Hematological Diseases” Guest Editor: Prof. Dr. Pier Paolo Piccaluga Submission deadline: 15 December 2025	“Feature Papers in Thalassemia Reports” Collection Editors: Prof. Dr. Aurelio Maggio and Dr. Khaled Musallam

In 2025, our Section “Pulmonology” was renamed to “Respiratory Medicine”. This Section of Journal of Clinical Medicine (JCM, ISSN: 2077-0383) is dedicated to all aspects of respiratory medicine, including the study of healthy and diseased lungs, airways, sleep medicine, and breathing. You are welcome to read the 2024 highly cited papers and find the latest publications through the following link: https://www.mdpi.com/search?journal=jcm&section=507.

In addition, the “Respiratory Medicine” Section is accepting submissions for several Special Issues. Please find below a list of relevant articles and Special Issues:

 1. “A Comprehensive Review of Risk Factors and Thrombophilia Evaluation in Venous Thromboembolism”
by Andrew B. Dicks, Elie Moussallem, Marcus Stanbro, Jay Walls, Sagar Gandhi and Bruce H. Gray
J. Clin. Med. 2024, 13(2), 362; https://doi.org/10.3390/jcm13020362
Full text available online: https://www.mdpi.com/2077-0383/13/2/362

2. “Developing a Virtual Reality Simulation System for Preoperative Planning of Robotic-Assisted Thoracic Surgery”
by Hideki Ujiie, Ryohei Chiba, Aogu Yamaguchi, Shunsuke Nomura, Haruhiko Shiiya, Aki Fujiwara-Kuroda, Kichizo Kaga, Chad Eitel, Tod R. Clapp and Tatsuya Kato
J. Clin. Med. 2024, 13(2), 611; https://doi.org/10.3390/jcm13020611
Full text available online: https://www.mdpi.com/2077-0383/13/2/611

3. “Using Artificial Intelligence to Predict Mechanical Ventilation Weaning Success in Patients with Respiratory Failure, Including Those with Acute Respiratory Distress Syndrome”
by Tamar Stivi, Dan Padawer, Noor Dirini, Akiva Nachshon, Baruch M. Batzofin and Stephane Ledot
J. Clin. Med. 2024, 13(5), 1505; https://doi.org/10.3390/jcm13051505
Full text available online: https://www.mdpi.com/2077-0383/13/5/1505

4. “Portal Vein Thrombosis: State-of-the-Art Review”
by Andrea Boccatonda, Simone Gentilini, Elisa Zanata, Chiara Simion, Carla Serra, Paolo Simioni, Fabio Piscaglia, Elena Campello and Walter Ageno
J. Clin. Med. 2024, 13(5), 1517; https://doi.org/10.3390/jcm13051517
Full text available online: https://www.mdpi.com/2077-0383/13/5/1517

5. “Advances in Non-Small Cell Lung Cancer: Current Insights and Future Directions”
by Pankaj Garg, Sulabh Singhal, Prakash Kulkarni, David Horne, Jyoti Malhotra, Ravi Salgia and Sharad S. Singhal
J. Clin. Med. 2024, 13(14), 4189; https://doi.org/10.3390/jcm13144189
Full text available online: https://www.mdpi.com/2077-0383/13/14/4189

6. “Pulmonary Function Tests: Easy Interpretation in Three Steps”
by Josuel Ora, Federica Maria Giorgino, Federica Roberta Bettin, Mariachiara Gabriele and Paola Rogliani
J. Clin. Med. 2024, 13(13), 3655; https://doi.org/10.3390/jcm13133655
Full text available online: https://www.mdpi.com/2077-0383/13/13/3655

7. “Enhancing Pulmonary Embolism Mortality Risk Stratification Using Machine Learning: The Role of the Neutrophil-to-Lymphocyte Ratio”
by Minodora Teodoru, Mihai Octavian Negrea, Andreea Cozgarea, Dragoș Cozma and Adrian Boicean
J. Clin. Med. 2024, 13(5), 1191; https://doi.org/10.3390/jcm13051191
Full text available online: https://www.mdpi.com/2077-0383/13/5/1191

8. “Tele-Monitoring Applications in Respiratory Allergy”
by Xenofon Aggelidis, Maria Kritikou, Michael Makris, Michael Miligkos, Niki Papapostolou, Nikolaos G. Papadopoulos and Paraskevi Xepapadaki
J. Clin. Med. 2024, 13(3), 898; https://doi.org/10.3390/jcm13030898
Full text available online: https://www.mdpi.com/2077-0383/13/3/898

9. “The Efficacy of Continuous Serratus Anterior and Erector Spinae Plane Blocks vs Intercostal Nerve Block in Uniportal-Vats Surgery: A Propensity-Matched Prospective Trial”
by Dania Nachira, Giovanni Punzo, Giuseppe Calabrese, Flaminio Sessa, Maria Teresa Congedo, Giovanna Beccia, Paola Aceto, Khrystyna Kuzmych, Chiara Cambise, Carolina Sassorossi et al.
J. Clin. Med. 2024, 13(2), 606; https://doi.org/10.3390/jcm13020606
Full text available online: https://www.mdpi.com/2077-0383/13/2/606

10. “The Impact of Antimicrobial Resistance in Cystic Fibrosis”
by Antonio Vitiello, Francesco Blasi, Michela Sabbatucci, Andrea Zovi, Francesco Miele, Annarita Ponzo, Roberto Langella and Mariarosaria Boccellino
J. Clin. Med. 2024, 13(6), 1711; https://doi.org/10.3390/jcm13061711
Full text available online: https://www.mdpi.com/2077-0383/13/6/1711

Special Issues
“Lung Transplantation: Current Strategies and Future Directions” Guest Editors: Dr. Omer Senbaklavaci and Dr. György Lang Submission deadline: 15 January 2026	“Bronchoscopy and Interventional Pulmonology” Guest Editors: Dr. Bryan S. Benn and Dr. Jonathan Kurman Submission deadline: 20 January 2026
“Thoracic Surgery: Updates and New Trends” Guest Editor: Dr. Monica Casiraghi Submission deadline: 31 January 2026	“Update on Acute Severe Respiratory Infections: 2nd Edition” Guest Editor: Prof. Dr. Jean-Francois Timsit Submission deadline: 31 January 2026

International Albinism Awareness Day 2025 underscores the urgent need for increased awareness, preventive care, and accessible healthcare for people with albinism. This year’s theme highlights the life-threatening impact of skin cancer among individuals with albinism and reinforces the importance of sun protection, early detection, and timely treatment.

Albinism is a rare, inherited genetic condition that affects the body’s ability to produce melanin, the pigment responsible for the color of our skin, hair, and eyes. People with albinism typically have very light skin and hair, alongside various vision impairments. While it is not contagious and does not affect intelligence, albinism is often misunderstood. This leads to stigmatization, discrimination, and even human rights violations in some regions where harmful myths persist.

Because they have little to no melanin, individuals with albinism are especially vulnerable to sun damage and face a significantly increased risk of developing skin cancer. Addressing this requires more than just clinical intervention—it calls for integrated healthcare policies and inclusive social systems that acknowledge both the medical and socio-political dimensions of the condition.

In recognition of this global observance, we invite you to explore a curated collection of articles and Special Issues from selected MDPI journals, including Biomedicines, Cancers, Children, Diagnostics, Genes, International Journal of Molecular Sciences, Journal of Clinical Medicine and Molecules. These open-access resources provide critical insights into the diagnosis, management, and complications of albinism, and promote cross-disciplinary collaboration between researchers, clinicians, and advocacy groups.

Together, through science, education, and empathy, we can foster a more inclusive world where people with albinism live free from discrimination and with access to the care they deserve.

“Can a Portable Flash Visual Evoked Potential (VEP) Device Identify Chiasmal Decussation Anomalies in Albinism?”
by Eloise Keeling, Perry Carter, Abdi Malik Musa, Fatima Shawkat, Helena Lee and Jay E. Self
Diagnostics 2025, 15(11), 1395; https://doi.org/10.3390/diagnostics15111395

“Common Variants in the TYR Gene with Unclear Pathogenicity as the Cause of Oculocutaneous Albinism in a Cohort of Russian Patients”
by Olga Shchagina, Anna Stepanova, Polina Mishakova, Vitaliy Kadyshev, Nina Demina, Ludmila Bessonova, Sofya Ionova, Daria Guseva, Andrey Marakhonov, Rena Zinchenko et al.
Biomedicines 2024, 12(10), 2234; https://doi.org/10.3390/biomedicines12102234

“Functional Characterization of Splice Variants in the Diagnosis of Albinism”
by Modibo Diallo, Cécile Courdier, Elina Mercier, Angèle Sequeira, Alicia Defay-Stinat, Claudio Plaisant, Shahram Mesdaghi, Daniel Rigden, Sophie Javerzat, Eulalie Lasseaux et al.
Int. J. Mol. Sci. 2024, 25(16), 8657; https://doi.org/10.3390/ijms25168657

“Genetic Linkage between CAPN5 and TYR Variants in the Context of Albinism and Autosomal Dominant Neovascular Inflammatory Vitreoretinopathy Absence: A Case Report”
by Mirjana Bjeloš, Ana Ćurić, Mladen Bušić, Benedict Rak and Biljana Kuzmanović Elabjer
Int. J. Mol. Sci. 2024, 25(12), 6442; https://doi.org/10.3390/ijms25126442

“Missing Heritability in Albinism: Deep Characterization of a Hungarian Albinism Cohort Raises the Possibility of the Digenic Genetic Background of the Disease”
by Nikoletta Nagy, Margit Pal, Jozsef Kun, Bence Galik, Peter Urban, Marta Medvecz, Beata Fabos, Alexandra Neller, Aliasgari Abdolreza, Judit Danis, Viktoria Szabo, Zhuo Yang, Stefanie Fenske, Martin Biel, Attila Gyenesei, Eva Adam and Marta Szell
Int. J. Mol. Sci. 2024, 25(2), 1271; https://doi.org/10.3390/ijms25021271

“Does Foveal Hypoplasia Affect Emmetropization in Patients with Albinism?”
by Line Kessel, Christine Dahlgren Bohnsack Kjølholm and Joaquim Torner Jordana
Children 2023, 10(12), 1910; https://doi.org/10.3390/children10121910

“Vision-Related Quality of Life in Danish Patients with Albinism and the Impact of an Updated Optical Rehabilitation”
by Kristian Lisbjerg, Joaquim Torner Jordana, Vibeke N. Brandt, Christine Kjølholm and Line Kessel
J. Clin. Med. 2023, 12(17), 5451; https://doi.org/10.3390/jcm12175451

“Skin Pigmentation Types, Causes and Treatment—A Review”
by Amin Mahmood Thawabteh, Alaa Jibreen, Donia Karaman, Alà Thawabteh and Rafik Karaman
Molecules 2023, 28(12), 4839; https://doi.org/10.3390/molecules28124839

“Report of Hermansky–Pudlak Syndrome in Two Families with Novel Variants in HPS3 and HPS4 Genes”
by Sadeeda Qaiser Zaman, Muhammad Anas, Gauhar Rehman, Qadeem Khan, Aiman Iftikhar, Mashal Ahmad, Muhammad Owais, Ilyas Ahmad, Osama Yousef Muthaffar, Angham Abdulrhman Abdulkareem et al.
Genes 2023, 14(1), 145; https://doi.org/10.3390/genes14010145

“Diagnostic Yield of Genetic Testing for Ocular and Oculocutaneous Albinism in a Diverse United States Pediatric Population”
by Kyle S. Chan, Brenda L. Bohnsack, Alexander Ing, Andy Drackley, Valerie Castelluccio, Kevin X. Zhang, Hanta Ralay-Ranaivo and Jennifer L. Rossen
Genes 2023, 14(1), 135; https://doi.org/10.3390/genes14010135

“More than Skin Deep—Latest Advances in Congenital and Autoimmune Pigmentation Disorders” Guest Editor: Prof. Dr. Reinhart M. Speeckaert Submission deadline: 25 August 2025	“Melanin Pigmentation: Physiology and Pathology” Guest Editors: Prof. Dr. Shosuke Ito and Prof. Dr. Manickam Sugumaran Submission deadline: 20 October 2025

To date, 2064 papers have been published in the “Ophthalmology” Section of Journal of Clinical Medicine (JCM, ISSN: 2077-0383). You are welcome to read the 2024 highly cited papers and find the latest publications through the following link: https://www.mdpi.com/search?journal=jcm&section=501.

• Ophthalmology and eye disease;
• Diagnosis, epidemiology, treatment, and management of ophthalmic disorders/conditions, Innovative approaches for analytics;
• Novel imaging of disease biomarkers;
• Genomics and bioinformatics related to clinical or pre-clinical research, and clinical studies that elucidate eye disease mechanisms; 
• Novel therapies for blinding disorders;
• Clinical practice of telemedicine in ophthalmology;
• Vulnerable populations and ophthalmic disease disparities;
• Co-segregating diseases, with examples including disease protection, therapy resistance, disease progression, and disease severity.

Some Special Issues in the “Ophthalmology” Section are currently open for submissions. The following is a list of articles and Special Issues that we believe may interest you:

1. “Efficacy and Safety of Low-Dose Atropine on Myopia Prevention in Premyopic Children: Systematic Review and Meta-Analysis”
by Ssu-Hsien Lee, Bor-Yuan Tseng, Jen-Hung Wang and Cheng-Jen Chiu
J. Clin. Med. 2024, 13(5), 1506; https://doi.org/10.3390/jcm13051506
Full text available online: https://www.mdpi.com/2077-0383/13/5/1506

2. “Impact of Brightness on Choroidal Vascularity Index”
by Nicola Rosa, Marco Gioia, Rachele Orlando, Martina De Luca, Eleonora D’Aniello, Isabella Fioretto, Ciro Sannino and Maddalena De Bernardo
J. Clin. Med. 2024, 13(4), 1020; https://doi.org/10.3390/jcm13041020
Full text available online: https://www.mdpi.com/2077-0383/13/4/1020

3. “Optic Nerve Neuroprotection in Glaucoma: A Narrative Review”
by Angela D’Angelo, Livio Vitiello, Filippo Lixi, Giulia Abbinante, Alessia Coppola, Vincenzo Gagliardi, Alfonso Pellegrino and Giuseppe Giannaccare
J. Clin. Med. 2024, 13(8), 2214; https://doi.org/10.3390/jcm13082214
Full text available online: https://www.mdpi.com/2077-0383/13/8/2214

4. “The Treatment of Diabetic Retinal Edema with Intravitreal Steroids: How and When”
by Maria Letizia Salvetat, Francesco Pellegrini, Leopoldo Spadea, Carlo Salati, Mutali Musa, Caterina Gagliano and Marco Zeppieri
J. Clin. Med. 2024, 13(5), 1327; https://doi.org/10.3390/jcm13051327
Full text available online: https://www.mdpi.com/2077-0383/13/5/1327

5. “Myopia Is an Ischemic Eye Condition: A Review from the Perspective of Choroidal Blood Flow”
by Baksh, Jiaul, Deokho Lee, Kiwako Mori, Yan Zhang, Hidemasa Torii, Heonuk Jeong, Jing Hou, Kazuno Negishi, Kazuo Tsubota and Toshihide Kurihara
J. Clin. Med. 2024, 13(10), 2777; https://doi.org/10.3390/jcm13102777
Full text available online: https://www.mdpi.com/2077-0383/13/10/2777

6. “Summary of the Therapeutic Options for Patients with Dry and Neovascular AMD”
by Dorota Śpiewak, Łukasz Drzyzga, Mariola Dorecka and Dorota Wyględowska-Promieńska
J. Clin. Med. 2024, 13(14), 4227; https://doi.org/10.3390/jcm13144227
Full text available online: https://www.mdpi.com/2077-0383/13/14/4227

7. “Drusen in AMD from the Perspective of Cholesterol Metabolism and Hypoxic Response”
by Norimitsu Ban, Ari Shinojima, Kazuno Negishi and Toshihide Kurihara
J. Clin. Med. 2024, 13(9), 2608; https://doi.org/10.3390/jcm13092608
Full text available online: https://www.mdpi.com/2077-0383/13/9/2608

8. “Unveiling Ocular Manifestations in Systemic Lupus Erythematosus”
by Mutali Musa, Ekele Chukwuyem, Oluwasola Michael Ojo, Efioshiomoshi Kings Topah, Leopoldo Spadea, Carlo Salati, Caterina Gagliano and Marco Zeppieri
J. Clin. Med. 2024, 13(4), 1047; https://doi.org/10.3390/jcm13041047
Full text available online: https://www.mdpi.com/2077-0383/13/4/1047

9. “From Clinical Suspicion to Diagnosis: A Review of Diagnostic Approaches and Challenges in Fungal Keratitis”
by Panagiotis Toumasis, Andreas G. Tsantes, Anastasia Tsiogka, George Samonis and Georgia Vrioni
J. Clin. Med. 2024, 13(1), 286; https://doi.org/10.3390/jcm13010286
Full text available online: https://www.mdpi.com/2077-0383/13/1/286

10. “Biomimetic Curcumin-Loaded Liposomes for the Treatment of Dry Eyes and Meibomian Gland Dysfunction: An In Vivo Study”
by Vytautas Baranauskas, Ruta Jaruseviciene, Mantas Grigalavicius, Saulius Galgauskas, Vitalijus Karabanovas and Simona Steponkiene
J. Clin. Med. 2024, 13(21), 6436; https://doi.org/10.3390/jcm13216436
Full text available online: https://www.mdpi.com/2077-0383/13/21/6436

Special Issues:
“Cataract and Refractive Surgery and Intraocular Lens Implantation: Clinical Advances and Perspectives” Guest Editor: Dr. Janusz Skrzypecki Submission deadline: 15 December 2025	“Innovations in the Clinical Management of Retinal Diseases: Emerging Therapies and Visual Rehabilitation” Guest Editor: Dr. Francisco J. Povedano-Montero Submission deadline: 19 December 2025
“Multifactorial Causation and Therapies of Myopia: 2nd Edition” Guest Editors: Prof. Dr. César Villa Collar, Dr. Cristina Alvarez-Peregrina and Prof. Dr. David Piñero Submission deadline: 26 December 2025	“Clinical Challenges and Advances in Dry Eye Disease and Meibomian Gland Dysfunction” Guest Editors: Dr. Salvatore Troisi and Dr. Livio Vitiello Submission deadline: 31 December 2025

We are delighted to share the notable papers published in Journal of Clinical Medicine (JCM, ISSN: 2077-0383). During Q1 of 2025, these papers received high Altmetric Attention Scores. The Altmetric Attention Score is a high-level measure of the quality and quantity of online attention that a paper has received. The scoring algorithm takes various factors into account. Altmetric Attention Scores can be found on the right side of a paper’s webpage.

The scope of notable papers covers gastrointestinal disease intervention, metabolic disease mechanism exploration, the precise treatment of inflammatory diseases, progress in the diagnosis and treatment of cardiovascular diseases, prevention and treatment of infectious diseases, and treatment of blood emergencies, focusing on cutting-edge academic hotspots and continuing to provide an important reference for clinical medical research and practice. Each article reflects the outstanding contributions of leading researchers and institutions, demonstrating rigorous scholarships and insights.

We extend our sincere appreciation to all authors and research teams for their exceptional work. These publications not only advance scientific understanding but also serve as valuable references for scholars and practitioners globally.

1．“Lipedema: Complications in High-Volume Liposuction Are Linked to Preoperative Anemia”
by Tonatiuh Flores, Barbara Kremsner, Jana Schön, Julia Riedl, Hugo Sabitzer, Christina Glisic, Kristina Pfoser, Jakob Nedomansky, Konstantin D. Bergmeister and Klaus F. Schrögendorfer
J. Clin. Med. 2024, 13(24), 7779; https://doi.org/10.3390/jcm13247779
Full text available online:https://www.mdpi.com/2077-0383/13/24/7779

2. “Two Different Hemodynamic Responses in ME/CFS Patients with Postural Orthostatic Tachycardia Syndrome During Head-Up Tilt Testing”
by C. (Linda) M. C. van Campen, Peter C. Rowe and Frans C. Visser
J. Clin. Med. 2024, 13(24), 7726; https://doi.org/10.3390/jcm13247726
Full text available online: https://www.mdpi.com/2077-0383/13/24/7726

3. “Antiphospholipid Syndrome: A Comprehensive Clinical Review”
by Vasileios Patriarcheas, Georgios Tsamos, Dimitra Vasdeki, Elias Kotteas, Anastasios Kollias, Dimitris Nikas, Georgia Kaiafa and Evangelos Dimakakos
J. Clin. Med. 2025, 14(3), 733; https://doi.org/10.3390/jcm14030733
Full text available online: https://www.mdpi.com/2077-0383/14/3/733

4. “Efficacy of Dietary Interventions for Irritable Bowel Syndrome: A Systematic Review and Network Meta-Analysis”
by Hossein Haghbin, Fariha Hasan, Manesh Kumar Gangwani, Nurruddinkhodja Zakirkhodjaev, Wade Lee-Smith, Azizullah Beran, Faisal Kamal, Benjamin Hart and Muhammad Aziz
J. Clin. Med. 2024, 13(24), 7531; https://doi.org/10.3390/jcm13247531
Full text available online: https://www.mdpi.com/2077-0383/13/24/7531

5. “Echocardiography in the Ventilated Patient: What the Clinician Has to Know”
by Fiorella Chiara Delle Femine, Diego D’Arienzo, Biagio Liccardo, Maria Concetta Pastore, Federica Ilardi, Giulia Elena Mandoli, Simona Sperlongano, Alessandro Malagoli, Matteo Lisi and Giovanni Benfari et al.
J. Clin. Med. 2025, 14(1), 77; https://doi.org/10.3390/jcm14010077
Full text available online: https://www.mdpi.com/2077-0383/14/1/77

6. “Cardiometabolic Markers in Algerian Obese Subjects with and Without Type 2 Diabetes: Adipocytokine Imbalance as a Risk Factor”
by Hassiba Benbaibeche, Abdenour Bounihi, Hamza Saidi, Elhadj Ahmed Koceir and Naim Akhtar Khan
J. Clin. Med. 2025, 14(5), 1770; https://doi.org/10.3390/jcm14051770
Full text available online: https://www.mdpi.com/2077-0383/14/5/1770

7. “Paradigm Shift in Inflammatory Bowel Disease Management: Precision Medicine, Artificial Intelligence, and Emerging Therapies”
by Antonio M. Caballero Mateos, Guillermo A. Cañadas de la Fuente and Beatriz Gros
J. Clin. Med. 2025, 14(5), 1536; https://doi.org/10.3390/jcm14051536
Full text available online: https://www.mdpi.com/2077-0383/14/5/1536

8. “Beyond Pulmonary Vein Reconnection: Exploring the Dynamic Pathophysiology of Atrial Fibrillation Recurrence After Catheter Ablation”
by Panayotis K. Vlachakis, Panagiotis Theofilis, Anastasios Apostolos, Paschalis Karakasis, Nikolaos Ktenopoulos, Aristi Boulmpou, Maria Drakopoulou, Ioannis Leontsinis, Panagiotis Xydis, Athanasios Kordalis et al.
J. Clin. Med. 2025, 14(9), 2919; https://doi.org/10.3390/jcm14092919
Full text available online: https://www.mdpi.com/2077-0383/14/9/2919

9. “Rethinking the Assessment of Arthrogenic Muscle Inhibition After ACL Reconstruction: Implications for Return-to-Sport Decision-Making—A Narrative Review”
by Florian Forelli, Ayrton Moiroux-Sahraoui, Jean Mazeas, Jonathan Dugernier and Adrien Cerrito
J. Clin. Med. 2025, 14(8), 2633; https://doi.org/10.3390/jcm14082633
Full text available online: https://www.mdpi.com/2077-0383/14/8/2633

10. “Predominant Pneumococcal Serotypes in Isolates Causing Invasive Disease in a Spanish Region: An Examination of Their Association with Clinical Factors, Antimicrobial Resistance, and Vaccination Coverage”
by Laura Diab-Casares, Nuria Tormo-Palop, Fco Javier Hernández-Felices, Violeta Artal-Muñoz, Pedro Floría-Baquero, José Luis Martin-Rodríguez, Rafael Medina-González, Sonia Cortés-Badenes, Begoña Fuster-Escrivá, Ana Gil-Bruixola et al.
J. Clin. Med. 2025, 14(5), 1612; https://doi.org/10.3390/jcm14051612
Full text available online: https://www.mdpi.com/2077-0383/14/5/1612

11. “Advances in Atrial Fibrillation Management: A Guide for General Internists”
by Hoang Nhat Pham, Ramzi Ibrahim, Hong Hieu Truong, Enkhtsogt Sainbayar, Viet Nghi Tran, Mahmoud Abdelnabi, Christopher Kanaan and Aadhavi Sridharan
J. Clin. Med. 2024, 13(24), 7846; https://doi.org/10.3390/jcm13247846
Full text available online: https://www.mdpi.com/2077-0383/13/24/7846

12. “Bedside Assessment of the Respiratory System During Invasive Mechanical Ventilation”
by Lorenzo Giosa, Patrick D. Collins, Sridevi Shetty, Marta Lubian, Riccardo Del Signore, Mara Chioccola, Francesca Pugliese and Luigi Camporota
J. Clin. Med. 2024, 13(23), 7456; https://doi.org/10.3390/jcm13237456
Full text available online: https://www.mdpi.com/2077-0383/13/23/7456

13. “Emergencies in Hematology: Why, When and How I Treat?”
by Andrea Duminuco, Vittorio Del Fabro, Paola De Luca, Dario Leotta, Miriana Carmela Limoli, Ermelinda Longo, Antonella Nardo, Gabriella Santuccio, Alessandro Petronaci, Gaia Stanzione et al.
J. Clin. Med. 2024, 13(24), 7572; https://doi.org/10.3390/jcm13247572
Full text available online: https://www.mdpi.com/2077-0383/13/24/7572

14. “Septic Cardiomyopathy: Difficult Definition, Challenging Diagnosis, Unclear Treatment”
by George E. Zakynthinos, Grigorios Giamouzis, Andrew Xanthopoulos, Evangelos Oikonomou, Konstantinos Kalogeras, Nikitas Karavidas, Ilias E. Dimeas, Ioannis Gialamas, Maria Ioanna Gounaridi, Gerasimos Siasos et al.
J. Clin. Med. 2025, 14(3), 986; https://doi.org/10.3390/jcm14030986
Full text available online: https://www.mdpi.com/2077-0383/14/3/986

Journal of Clinical Medicine (JCM, ISSN: 2077-0383) is pleased to announce the launch of a new Section: “Clinical Nutrition & Dietetics”. We have a total of 37 Sections to cover all topics related to clinical and pre-clinical practices.

“Clinical Nutrition & Dietetics” is a specialized Section within the field of medical and health sciences that focuses on the scientific study and application of nutrition and dietetics in clinical settings. This Section aims to provide a platform for clinicians, nutritionists, dietitians, and other healthcare professionals to present cutting-edge research, evidence-based practice guidelines, and quality clinical services related to clinical nutrition and dietetics.

This Section is particularly dedicated, but not limited, to the following areas of research:

• Clinical nutrition assessment and management;
• Medical nutrition therapy;
• Enteral and parenteral nutrition;
• Nutrition and disease;
• Public health nutrition;
• Special dietary needs;
• Obesity;
• Vitamins and minerals;
• Energy metabolism;
• Dietary interventions;
• Eating disorders;
• Bariatric surgery;
• Sarcopenia.

Please find more details at https://www.mdpi.com/journal/jcm/sections/Clinical_Nutrition_Dietetics.

The “Clinical Nutrition & Dietetics” Section is currently recruiting Editorial Board Members (EBMs), Guest Editors, and volunteer reviewers.

The relevant requirement information can be found at:

• https://www.mdpi.com/editors;
• https://www.mdpi.com/special_issues_guidelines;
• https://www.mdpi.com/reviewers#5_Volunteer_Reviewers.

We are pleased to announce that the Journal of Clinical Medicine (JCM, ISSN: 2077-0383) is now inviting nominations for the JCM 2025 Young Investigator Award. This prize will be given to one young investigator in recognition of their excellence in the field of clinical medicine. All the nominations will be assessed by an Award Evaluation Committee led by the Editors-in-Chief, Prof. Dr. Emmanuel Andrès and Prof. Dr. Kent Doi.

The prize includes:

• CHF 2000;
• The option to publish one paper free of charge in JCM after peer review before the end of 2026;
• An electronic certificate.

Eligibility and requirements:

• The candidate must have received their Ph.D. no more than 10 years prior to 31 December 2025;
• The candidate must have produced ground-breaking research and made a significant contribution to the advancement of clinical medicine;
• The candidate must be nominated by senior scientists.

List of documents for nomination:

• Detailed curriculum vitae, including an updated publication list and a list of the researcher’s own research grants;
• Scanned copy of their doctorate certificate;
• Signed nomination letters from two established senior scientists.

Nomination deadline: 31 December 2025.

You can find more information about this award and how to nominate here. To request further information, please contact the JCM Editorial Office.

Journal of Clinical Medicine Editorial Office