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Antibiotics
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Global Partnerships in Response to Antimicrobial Resistance: From Policy to...
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Global Partnerships in Response to Antimicrobial Resistance: From Policy to Practice

A special issue of Antibiotics (ISSN 2079-6382). This special issue belongs to the section "Antibiotics Use and Antimicrobial Stewardship".

Deadline for manuscript submissions: 31 March 2026 | Viewed by 529

Special Issue Editor

Dr. Helena Rosado

E-Mail Website
Guest Editor
Commonwealth Pharmacists Association, London E1W 1AW, UK
Interests: global and public health; multidisciplinary and collaborative work; education; equity in healthcare; pharmacy; antimicrobial resistance and stewardship

Special Issue Information

Dear Colleagues,

Antimicrobial resistance (AMR) poses a critical threat to global health, disproportionally affecting low- and middle-income countries (LMICs) where health systems face infrastructure and resource constraints. While robust policy frameworks are essential, addressing AMR also requires actionable implementation through effective, real-word interventions and innovation.

This Special Issue aims to highlight the unique intersection of global health partnerships in AMR, with a particular focus on initiatives in LMICs—from strategic frameworks to on-the-ground impact.

We welcome contributions from professionals across the health sector—from academics, researchers, and policy makers to healthcare providers, implementers, and community health workers—sharing their practical experiences, innovations, and evidence-based solutions. Submissions may include original research, case-studies, and policy analyses that explore the design and implementation of AMR interventions, the influence of health partnerships, multidisciplinary, and collaborative work on national, regional, and local practices, and lessons learnt from global health initiatives.

By showcasing real-world solutions and fostering dialogue in the global health arena, this Special Issue aims to deepen understanding of how global health partnerships and collaborations drive sustainable progress, from policy to practice, for the contention of AMR.

Dr. Helena Rosado
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 250 words) can be sent to the Editorial Office for assessment.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Antibiotics is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2900 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • antimicrobial resistance
  • antimicrobial stewardship
  • global health partnerships
  • collaboration
  • low- and middle-income countries
  • health systems strengthening
  • actionable implementation
  • AMR interventions

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Published Papers (1 paper)

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18 pages, 711 KB  
Protocol
A Hybrid Type II Hub-and-Spoke Model Evaluation Framework in the Commonwealth Partnerships for Antimicrobial Stewardship Programme—A Study Protocol
by Ayesha Iqbal, Gizem Gülpinar, Claire Brandish, Maxencia Nabiryo, Frances Garraghan and Victoria Rutter
Antibiotics 2025, 14(12), 1218; https://doi.org/10.3390/antibiotics14121218 - 3 Dec 2025
Viewed by 204
Abstract
Introduction: The hub-and-spoke model (HSM) offers a methodological and hierarchical project management framework for efficient healthcare service delivery. The Commonwealth Partnerships for Antimicrobial Stewardship (CwPAMS) programme supports the development and implementation of antimicrobial stewardship (AMS) interventions to optimise the use of antimicrobials across [...] Read more.
Introduction: The hub-and-spoke model (HSM) offers a methodological and hierarchical project management framework for efficient healthcare service delivery. The Commonwealth Partnerships for Antimicrobial Stewardship (CwPAMS) programme supports the development and implementation of antimicrobial stewardship (AMS) interventions to optimise the use of antimicrobials across eight African countries: Ghana, Kenya, Malawi, Nigeria, Sierra Leone, Tanzania, Uganda, and Zambia. Currently the second phase of the programme (CwPAMS 2.0) is being implemented, between March 2023 and March 2025, in which six countries are adopting the HSM to deliver AMS interventions. The aim of this study was to design a hybrid II monitoring, evaluation and learning (MEL) framework to assess the implementation and effectiveness of the HSM in delivering and adapting AMS interventions. Methods: A mixed-methods Hybrid II Implementation trial design was used to develop the MEL framework, guided by the Theory of Change, Socio-Ecological Theory, and Normalisation Process Theory and in alignment with the Reach, Effectiveness, Adoption, Implementation, and Maintenance (RE-AIM) framework. Data collection will be continuous and longitudinal (pre-, mid- and post-implementation). The evaluation framework has been designed to study implementation evaluation at three ecological levels: programme, partnership, and individual site level. Data collection will encompass mixed methodologies and include non-participant observations, formal and informal feedback (from individual key stakeholders and groups), knowledge tools and surveys, scored evaluations, pre-and post-assessments, semi-structured interviews, focus groups, and data collected during formal and informal meetings. This approach will facilitate continuous data collection for evaluation and help study the utilisation and adaptation of AMS interventions. Discussion: This study provides a protocol for developing and utilising an MEL framework to study the application of the HSM in delivering AMS interventions. Developing an evaluation framework requires meticulous planning and a robust implementation and evaluation protocol to ensure methodological rigour, transparency, and effective resource management throughout the project lifecycle. Despite comprehensive consideration of developing progress and programmatic indicators and measures across all domains, the study acknowledges limitations in definitively attributing causality to individual AMS interventions due to their complexity and varied implementation contexts. Full article
(This article belongs to the Special Issue Global Partnerships in Response to Antimicrobial Resistance: From Policy to Practice)
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