The High-performance Integrated Virtual Environment (HIVE) is a high-throughput cloud-based infrastructure developed for the storage and analysis of genomic and associated biological data. HIVE consists of a web-accessible interface for authorized us...
Background/Objectives: Hemoglobinopathies, including thalassemia and sickle cell disease, are among the most common inherited disorders worldwide. This study aimed to profile hemoglobin variants in the Tharu community of Lakhimpur Kheri, Uttar Prades...
Fermentation technology is of great significance for food preservation; through fermentation, while extending the shelf life of food, it can also improve the sensory quality of food and increase its nutritional value. Compared with natural fermentati...
This study investigates the combined influence of superabsorbent polymers (SAPs) with distinct absorption kinetics and extended mixing sequences on the rheological, mechanical, and transport properties of high-performance concrete (HPC). Two SAPs&mda...
To provide precision medicine for better cancer care, researchers must work on clinical patient data, such as electronic medical records, physiological measurements, biochemistry, computerized tomography scans, digital pathology, and the genetic land...
An ever-increasing amount of research is being performed on the stability and recovery of soil methane-oxidizing bacteria since this is one of the fundamental processes controlling the amount of methane in the atmosphere. Mineral fertilizers may alte...
To express and purify staphylococcal enterotoxin M (SEM) using immobilized metal affinity chromatography (IMAC), a signal peptide-truncated (ΔNsp) wild-type SEM (SEMWT) was N-terminally fused in pET-28a(+) to a polyhistidine tag (His6×-)...
Among the cultivated crop species, the economically and culturally important grapevine plays host to the greatest number of distinctly characterized viruses. A critical component of the management and containment of these viral diseases in grapevine...
Multiple sequence alignment (MSA) stands as a critical tool for understanding the evolutionary and functional relationships among biological sequences. Obtaining an exact solution for MSA, termed exact-MSA, is a significant challenge due to the combi...
The general lack of knowledge on the conditions of Western Siberia (Omsk region) and the taxonomic diversity of zonal soils determines the relevance of these studies. The research was carried out in order to study the effect of complex biologics on t...
Background/Objectives: Transcriptome assembly and functional annotation are essential in understanding gene expression and biological function. Nevertheless, many existing pipelines lack the flexibility to integrate both short- and long-read sequenci...
Low-temperature (LT) is one of the major abiotic stresses that restrict the growth and development of maize seedlings. Brassinolides (BRs) have been shown to enhance LT tolerance in several plant species; the physiological and molecular mechanisms by...
In this study, brick plant waste was used to produce alkali-activated mortars. Four mixtures with identical compositions but different mixing sequences and curing methods were prepared. Two were conventionally produced using a pre-cooled 10 M potassi...
High-throughput sequencing (HTS) technologies and bioinformatic analyses are of growing interest to be used as a routine diagnostic tool in the field of plant viruses. The reliability of HTS workflows from sample preparation to data analysis and resu...
In order to investigate the enhancement mechanism of modified three-dimensional elastic filler (MTEF) on the nitrogen removal performance of the integrated fixed-film activated sludge (IFAS) process, and to clarify the interactions between competitio...
Positive plant–soil feedback depends on beneficial interactions between roots and microbes for nutrient acquisition; growth promotion; and disease suppression. Recent pyrosequencing approaches have provided insight into the rhizosphere bacterial comm...
Development of High-Throughput Sequencing (HTS), also known as next generation sequencing, revolutionized diagnostic research of plant viruses. HTS outperforms bioassays and molecular diagnostic assays that are used to screen domestic and quarantine...
In 2024, China generated approximately 130 million tons of food waste. This study focuses on food wastewater characterized by exceptionally high organic strength (chemical oxygen demand (COD) > 80 g·L−1, total suspended solids (TSS) &...
Food supplements are gaining popularity worldwide. However, harmful natural compounds can contaminate these products. In the case of algae-based products, the presence of toxin-producing cyanobacteria may cause health risks. However, data about the p...
Background/Objectives: Reliable molecular testing is essential for selecting targeted therapies for thyroid tumors; however, assay performance can be affected by pre-analytical tissue conditions. This retrospective, single-center study evaluated real...
A total of 24,000 healthy 1-day-old Arbor Acres broilers with similar initial weights were used in this study and fed a basal diet supplemented with 0, 400 and 800 mg/kg isoleucine (Ile), denoted CON, ILE400 and ILE800, respectively. Results revealed...
On 25 April 2015, a strong earthquake of magnitude 7.8 struck central Nepal including the capital city, Kathmandu. Several powerful aftershocks of magnitude 6.7, 6.9 and 7.3 together with hundreds of aftershocks of local magnitude greater than 4 hit...
The banana mild mosaic virus (BanMMV) (Betaflexiviridae, Quinvirinae, unassigned species) is a filamentous virus that infects Musa spp. and has a very wide geographical distribution. The current BanMMV indexing process for an accession requires the t...
Due to the continuous development in the field of Next Generation Sequencing (NGS) technologies that have allowed researchers to take advantage of greater genetic samples in less time, it is a matter of relevance to improve the existing algorithms ai...
Methylation is a chemical process that modifies DNA through the addition of a methyl group to one or several nucleotides. Discovering differentially methylated regions is an important research field in genomics, as it can help to anticipate the risk...
The duodenum is an important digestive organ for poultry and houses a variety of microbes that help chickens to enhance nutrient absorption and improve production. To evaluate the characteristic of gut microbiome, duodenum content samples from 42-wee...
In this study, we explored the gene expression patterns of the pituitary gland and hypothalamus of Angus cows at different growth and developmental stages by deep sequencing and we identified genes that affect bovine reproductive performance to provi...
Purpose: This study investigates the impact of different intensity normalization (IN) methods on the overall survival (OS) radiomics models’ performance of MR sequences in primary (pHGG) and recurrent high-grade glioma (rHGG). Methods: MR scans acqui...
A promoter is an important non-coding DNA sequence, as it can regulate gene expression. Its abnormalities are closely associated with various diseases, such as coronary heart disease, diabetes, and tumors. Therefore, promoter identification is highly...
Sequence files formats (FASTA and FASTQ) are commonly used in bioinformatics, molecular biology and biochemistry. With the advent of next-generation sequencing (NGS) technologies, the number of FASTQ datasets produced and analyzed has grown exponenti...
Today, new technologies, such as microarrays or high-performance sequencing, are producing more and more genomic data [...]
Understanding the genetic basis of high-performance animals is vital for biological insight and breeding. This study aimed to identify genetic factors distinguishing champion gamecocks (Gallus gallus domesticus) from less successful ones, representin...
Flaxseed (Linum usitatissimum L.) displays functional properties and contains α-linolenic acid (omega-3). It also contains soluble and insoluble fiber, lignans, phenolic acids, flavonoids, phytic acid, vitamins, and minerals. However, its micro...
Objectives: The main aims of the study were the evaluation of stress-related effects (strenuous vs. non-strenuous sport vs. nonathletes) in stimulating or reducing influences on cartilage volume in the ankle joint and the evaluation of the image qual...
Access to high-performance sports is crucial for the holistic development and well-being of athletes with intellectual impairment (II). However, ensuring fair and equitable participation requires effective eligibility systems. This study investigates...
Silk and silk-like proteins emerge as programmable building blocks for high-performance fiber materials because they can integrate mechanical robustness, biological compatibility, environmental responsiveness, and degradability within genetically def...
Metagenomic analysis, a technique used to comprehensively analyze microorganisms present in the environment, requires performing high-precision homology searches on large amounts of sequencing data, the size of which has increased dramatically with t...
We performed an enzymatic screening of synthetic peptides based on β-amyloid precursor protein substrates. The template peptide sequence was a decapeptide derived from our previous screening study, which determined several effective unnatural am...
Aptamers feature a number of advantages, compared to antibodies. However, their application has been limited so far, mainly because of the complex selection process. ‘High-throughput sequencing fluorescent ligand interaction profiling’ (HiTS–FLIP) si...
With the spread of COVID-19, sequencing laboratories started to share hundreds of sequences daily. However, the lack of a commonly agreed standard across deposition databases hindered the exploration and study of all the viral sequences collected wor...
Extracellular vesicles (EVs) released by bone marrow stromal cells (BMSCs) have been shown to act as a transporter of bioactive molecules such as RNAs and proteins in the therapeutic actions of BMSCs in various diseases. Although EV therapy holds gre...
Crocins are valuable bioactive components of gardenia fruit, and their biosynthesis and accumulation have attracted widespread interest. Studies have investigated the biosynthesis and accumulation of crocin based on Illumina sequencing, but there is...
In this study, a novel aperiodic photonic crystal (PC) structure is designed using the golden ratio-based Lucas sequence, and its infrared (IR) transmission characteristics are investigated. Transmission behavior demonstrates a strong dependence on t...
The size of spatial data is growing intensively due to the emergence of and the tremendous advances in technology such as sensors and the internet of things. Supporting high-performance queries on this large volume of data becomes essential in severa...
Epileptic seizure (ES) detection is critical for improving clinical outcomes in epilepsy management. While intracranial EEG (iEEG) provides high-quality neural recordings, existing detection methods often rely on large amounts of data, involve high c...
Surface-enhanced Raman scattering (SERS) technology, with its high sensitivity and fingerprinting capability, has shown broad application prospects in environmental monitoring, food safety, biomedicine, and other fields. Electrospinning technology ca...
This study explores the multi-objective optimization of flight sequencing in multi-runway airports using genetic algorithms. As air traffic continues to grow, airports face increasing pressure to optimize resource allocation. This research focuses on...
The COVID-19 pandemic has exposed the extent of global connectivity and collective vulnerability to emerging diseases. From its suspected origins in Wuhan, China, it spread to all corners of the world in a matter of months. The absence of high-perfor...
Fumonisins are mycotoxins produced by Fusarium verticillioides and F. proliferatum, fungi that are ubiquitous in corn (maize). Insect damage and some other environmental conditions result in the accumulation of fumonisins in corn-based products world...
Tick-borne encephalitis virus (TBEV) causes tick-borne encephalitis (TBE), a severe disease of the human central nervous system. Currently, the data on the genetic variants of TBEV in Kyrgyzstan are practically absent. Therefore, the aim of this stud...
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