The recent introduction of ABP 501, an adalimumab biosimilar, in the treatment of rheumatic diseases was supported by a comprehensive comparability exercise with its originator. On the other hand, observational studies comparing adalimumab and ABP 50...
Acetylated nanofibrillated cellulose (ANFC)/acrylic resin ABPE-10 composite film was prepared by impregnating ABPE-10 into ANFC films under negative pressure, which can enhance properties of ANFC films by forming an interpenetrating polymer network s...
Early cancer screening enables timely detection of carcinogenesis, and aids in prompt clinical intervention. Herein, we report on the development of a simple, sensitive, and rapid fluorometric assay based on the aptamer probe (aptamer beacon probe, A...
When observing the Earth’s radiation signal with a geostationary orbiting (GEO) mechanically scanned microwave radiometer, it is necessary to correct the antenna beam pointing (ABP) in real time for the deviation caused by thermal distortions of ante...
Auxin receptor plays a significant role in the plant auxin signalling pathway in response to abiotic stress. Recently, we found that transgenic rice overexpressing ABP57 had higher drought tolerance than the wild-type cultivar, MR219, due to the fact...
Ulcerative colitis (UC) is a chronic noninfectious intestinal disease that severely affects patients’ quality of life. Agaricus blazei Murrill polysaccharide (ABP) is an effective active ingredient extracted from Agaricus blazei Murrill (ABM)....
Effective biopreservation measures are needed to control the growth of postprocess Listeria monocytogenes contamination in fresh whey cheeses stored under refrigeration. This study assessed growth and biocontrol of inoculated (3 log10 CFU/g) L. monoc...
Over the past decade, the dose of nanoparticles given to solid tumors has remained at a median of 0.7% of the injected dose. Most nanoparticles are trapped in a mononuclear phagocyte system (MPS), of which 85% are Kupffer cells. In our study, thresho...
Proteases are important enzymes in health and disease. Their activities are regulated at multiple levels. In fact, proteases are synthesized as inactive proenzymes (zymogens) that are activated by proteolytic removal of their pro-peptide sequence and...
Endometriosis is a chronic, estrogen-dependent gynecological disorder characterized by the presence of endometrial-like tissue outside the uterine cavity. Despite its prevalence and significant impact on women’s health, the underlying mechanism...
An end-to-end joint source–channel (JSC) encoding matrix and a JSC decoding scheme using the proposed bit flipping check (BFC) algorithm and controversial variable node selection-based adaptive belief propagation (CVNS-ABP) decoding algorithm a...
Dual fuel engines constitute a viable solution for enhancing the environmental sustainability of the shipping operations. Although these engines comply with the Tier III NOx emissions regulations when operating at the gas mode, additional measures ar...
Auxin is one of the crucial regulators of plant growth and development. The discovered auxin cytosolic receptor (TIR1) is not involved in the perception of the hormone signal at the plasma membrane. Instead, another receptor, related to the ABP1, aux...
Cardiovascular diseases are one of the most severe causes of mortality, annually taking a heavy toll on lives worldwide. Continuous monitoring of blood pressure seems to be the most viable option, but this demands an invasive process, introducing sev...
To compare arterial blood pressure (ABP) measured invasively (IBP) to ABP measured non-invasively (NIBP) via oscillometry in healthy anaesthetised and standing horses using the Bionet BM7Vet. Fourteen horses were anaesthetised for elective procedures...
The mechanical behavior of block-in-matrix materials is heavily dependent on their block content. This parameter is in most cases obtained through visual analyses of the ground through digital imagery, which provides the areal block proportion (ABP)...
The actin cytoskeleton plays a crucial role in many cellular processes while its reorganization is important in maintaining cell homeostasis. However, in the case of cancer cells, actin and ABPs (actin-binding proteins) are involved in all stages of...
Blood pressure (BP) monitoring has significant importance in the treatment of hypertension and different cardiovascular health diseases. As photoplethysmogram (PPG) signals can be recorded non-invasively, research has been highly conducted to measure...
Five novel air- and moisture-stable polymetallic Ti and Zr amino acid-derived amine bis(phenolate) (ABP) complexes were synthesised and fully characterised, including X-ray crystallographic studies. The reaction of the ABP proligands with Ti or Zr al...
4-Aminobiphenyl (4-ABP) and other related arylamines have emerged to be responsible for human urinary bladder tumors and cancers. Hemoglobin-ABP adducts have been recognized in the blood of smokers, and it builds up in the circulatory system over the...
As antimicrobial resistance (AMR) continues to pose an ever-growing global health threat, propelling us into a post-antibiotic era, novel alternative therapeutic agents are urgently required. Lysins are bacteriophage-encoded peptidoglycan hydrolases...
Direct in vivo evidence of altered metabotropic glutamate receptor-5 (mGluR5) availability in alcohol-related disorders is lacking. We performed [11C]ABP688 positron emission tomography (PET) and resting-state functional magnetic resonance imaging (r...
Macroautophagy is a key adaptive process that enables tumour cells to withstand the cytotoxic stress induced by standard antitumour treatments, thereby contributing to therapeutic resistance. In this context, identifying regulators capable of modulat...
UVB radiation is known to induce photodamage to the skin, disrupt the skin barrier, elicit cutaneous inflammation, and accelerate the aging process. Agaricus blazei Murill (ABM) is an edible medicinal and nutritional fungus. One of its constituents,...
Enhancing crop stress tolerance to ensure global food security is one of the core challenges in agricultural science. Plants predominantly face biotic and abiotic stresses, to which they respond by activating finely regulated signal perception and tr...
During recent decades, the elderly population has grown rapidly, and the number of patients with chronic heart-related diseases has exploded. Many of them (e.g., congestive heart failure, some types of arrhythmia) require close medical supervision, i...
The clubroot disease, caused by the obligate biotrophic protist Plasmodiophora brassicae, affects cruciferous crops worldwide. It is characterized by root swellings as symptoms, which are dependent on the alteration of auxin and cytokinin metabolism....
Accurate State of Charge (SOC) estimation for lithium-ion batteries has great significance with respect to the correct decision-making and safety control. In this research, an improved second-order-polarization equivalent circuit (SO-PEC) modelling m...
Background: The success rates of treating chronic periprosthetic joint infection (PJI) have plateaued in the last two decades utilizing exchange protocols combined with extended parenteral antimicrobials. At the same time, extended systemic antimicro...
More than 50% of myeloma cases have normal karyotypes under conventional cytogenetic analysis due to low mitotic activity and content of plasma cells in the bone marrow. We used a polymerase chain reaction (PCR)-based translocation detection assay to...
Adventitious rooting is a process of postembryonic organogenesis strongly affected by endogenous and exogenous factors. Although adventitious rooting has been exploited in vegetative propagation programs for many plant species, it is a bottleneck for...
Deubiquitinases (DUBs) have been the subject of intense scrutiny in recent years. Many of their diverse enzymatic mechanisms are well characterized in vitro; however, our understanding of these enzymes at the cellular level lags due to the lack of qu...
Multi-drug resistance in bacteria is a major health problem worldwide. To overcome this issue, new approaches allowing for the identification and development of antibacterial agents are urgently needed. Peptides, due to their binding specificity and...
The plant actin cytoskeleton is characterized by the basic properties of dynamic array, which plays a central role in numerous conserved processes that are required for diverse cellular functions. Here, we focus on how actins and actin-related protei...
Fel d 1 is a cat protein abundantly released and found in their habitat and is closely related to mouse androgen-binding proteins (ABPs). We hypothesized that mice have developed chemical communication mechanisms to detect and avoid this protein. We...
Several studies showed that [11C]ABP688 binding is altered following drug-induced perturbation of glutamate levels in brains of humans, non-human primates and rats. We evaluated whether the fluorinated derivative [18F]PSS232 can be used to assess met...
Due to the increasing size of the population, society faces several challenges for sustainable and adequate agricultural production, quality, distribution, and food safety in the strategic project portfolio selection (SPPS). The initial adaptation of...
The ABP dendrimer, which is built on a phosphorus-based scaffold and bears twelve azabisphosphonate groups at its surface, is one of the dendrimers that has been shown to display immuno-modulatory and anti-inflammatory effects towards the human immun...
Positioning systems based on the lateration method utilize distance measurements and the knowledge of the location of the beacons to estimate the position of the target object. Although most of the global positioning techniques rely on beacons whose...
9 January 2024
One of the most significant indicators of heart and cardiovascular health is blood pressure (BP). Blood pressure (BP) has gained great attention in the last decade. Uncontrolled high blood pressure increases the risk of serious health problems, inclu...
Continuous arterial blood pressure (ABP) prediction is relevant to cardiovascular monitoring and development of adaptive patient-specific digital twins. This study presents an adaptive data-driven ABP prediction framework inspired by cardiovascular d...
GABA, the primary inhibitory neurotransmitter, stimulates GABAA receptors (GABAARs) to increase the chloride conductance of the cytosolic membrane. The driving forces for membrane chloride currents are determined by the local differences between intr...
MR219 transgenic rice line which overexpressed an auxin-binding protein (ABP57) and its wild-type cultivar, MR219, were screened under well-watered (WW) and drought stress (DS) conditions at the early reproductive stage. This study was conducted with...
Background and Objectives: The aim of this study was to explore the association between the cerebral autoregulation (CA) index, the pressure reactivity index (PRx), the patient’s clinical outcome, and the quality of arterial blood pressure (ABP...
Human cathepsin L belongs to the cathepsin family of proteolytic enzymes with primarily an endopeptidase activity. Although its primary functions were originally thought to be only of a housekeeping enzyme that degraded intracellular and endocytosed...
19 October 2020
Hyperbaric oxygen therapy (HBOT) is widely used to treat several pathologies. The hemodynamic changes during HBOT, particularly the magnitude of arterial blood pressure (ABP) increase, are not completely understood. No clinical predictors for HBOT-in...
Background/Objectives: Optimal management of acute bacterial prostatitis (ABP) remains uncertain, but the use of antibiotics with good prostatic tissue penetration is critical to prevent recurrence and chronic progression. This study aimed to describ...
The objective of this study was to evaluate the percentage of patients with primary arterial hypertension treated with antihypertensive drug(s), who achieved target arterial blood pressure (ABP), and to compare the characteristics of patients with co...
The experiment aimed to investigate the effects of probiotics and Achyranthes bidentata polysaccharides on the growth performance, nutrients digestibility, and immune function of weaned pigs. One hundred and twenty weaned pigs (about 7 kg BW, 23 ± 2...
Background/Objectives: Achyranthes bidentata (AB), recognized as a food and traditional Chinese medicine, exhibits notable biological activity. Our previous study showed the hypoglycemic effect of Achyrantha bidentata polysaccharide (ABP). The proper...
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