This study aimed to achieve bioactivity on the PEEK surface using piranha solution through a lower functionalization time. For this purpose, the functionalization occurred with piranha solution and 98% sulfuric acid in the proportions of 1:2, 1:1, an...
This study explores the potential of laser surface modification (LSM) to enhance the biological properties of melt-derived bioactive glasses, specifically 45S5 and ICIE16, which are key in medical implants due to their bone-regenerating capabilities....
Animal studies and the scarce clinical trials available that have been conducted suggest that bioactive surfaces on dental implants could improve the osseointegration of such implants. The purpose of this systematic review was to compare the effectiv...
Laser nanostructuring via Laser-Induced Periodic Surface Structures (LIPSS), generated using femtosecond laser pulses, has been investigated as a method for precisely modifying titanium surfaces. By adjusting parameters such as the fluence and pulse...
Monodispersed spherical Ag-doped bioactive glass nanoparticles (Ag-BGNs) were synthesized by a modified Stöber method combined with surface modification. The surface modification was carried out at 25, 60, and 80 °C, respectively, to investigate the...
Objective: To evaluate the surface micromorphology of bioactive glass-modified resin composite materials after storage in simulated body fluid for different periods of time and ultrasonic cleaning. Materials and methods: A resin composite material (H...
Silicon nitride (Si3N4) is a promising biomaterial, currently used in spinal fusion implants. Such implants should result in high vertebral union rates without major complications. However, pseudarthrosis remains an important complication that could...
Cardiovascular diseases continue to be a major contributor to illness and death on a global scale, and the implementation of stents has given rise to a revolutionary transformation in the field of interventional cardiology. The thrombotic and resteno...
Inert polymeric implants must evolve to enhance their biological interactions with host tissue, triggering positive cellular responses and promoting tissue bonding and integration. Poly-ether-ether-ketone (PEEK) is widely used as an implant material;...
The influence of cooling conditions and surface topography after finish turning of Ti6Al4V titanium alloy on corrosion resistance and surface bioactivity was analyzed. The samples were machined under dry and minimum quantity lubrication (MQL) conditi...
Bioactive glasses (BGs) are routinely being used as potent materials for hard and soft tissue engineering applications; however, improving their biological activities through surface functionalization and modification has been underestimated so far....
Bacterial infections and the lack of bioactivity of titanium implants and their alloys remain critical challenges for the long-term performance and clinical success of these devices. These issues arise from the undesirable combination of early microb...
The influence of surface treatments on the microstructure, in vitro bioactivity and corrosion protection performance of newly fabricated Ti-20Nb-13Zr (TNZ) alloys was evaluated in simulated body fluid (SBF). The TNZ alloy specimens were treated with...
The surface topography of dental implants plays an important role in cell-surface interaction promoting cell adhesion, proliferation and differentiation influencing osseointegration. A hydrophilic implant leads to the absorption of water molecules an...
At solid-liquid interfaces, charged particles within the electric double layer (EDL) are acted on by the electrostatic force, which may affect cell absorption and surface wettability. In this study, a model of the electrostatic force and surface tens...
Biphasic macroporous Hydroxyapatite/β-Tricalcium Phosphate (HA/β-TCP) scaffolds (BCPs) are widely used for bone repair. However, the high-temperature HA and β-TCP phases exhibit limited bioactivity (low solubility of HA, restricted sur...
The surface topography of dental implants and micro-nano surface characterization have gained particular interest for the improvement of the osseointegration phases. The aim of this study was to evaluate the surface micro-nanomorphology and bioactivi...
The colonisation of the surface of removable acrylic dentures by various types of microorganisms can lead to the development of various diseases. Therefore, the creation of a bioactive material is highly desirable. This study aimed to develop a dentu...
The bioactivity and biocompatibility play key roles in the success of dental and orthopaedic implants. Although most commercial implant systems use various surface microstructures, the ideal multi-scale topographies capable of controlling osteointegr...
The long-term success of orthopedic implants depends not only on their mechanical performance but also on their ability to establish a stable and biologically active interface with surrounding tissues. Despite the widespread clinical use of metallic,...
Here we introduce a new method aiming the immobilization of bioactive principles onto polymeric substrates, combining a surface activation and emulsion entrapment approach. Natural products with antimicrobial/antioxidant properties (essential oil fro...
Titanium (Ti) and its alloys have been demonstrated over the last decades to play an important role as inert materials in the field of orthopedic and dental implants. Nevertheless, with the widespread use of Ti, implant-associated rejection issues ha...
Background: Dental implants have become the standard for replacing missing teeth. However, patients’ demands for shorter treatment times and the desire for aesthetics in their results can complicate the rehabilitation process, particularly when...
In this study, the effects of substrate temperature and ablation wavelength/mechanism on the structural, mechanical, and bioactivity properties of hydroxyapatite (HA) coatings were investigated. HA coatings were deposited on both Si(100) and Ti6Al4V...
The increasing prevalence of orthopedic disorders and technological advances have significantly improved the design and functionality of orthopedic implants, fostering the growth of the orthopedic implant market. Polyetheretherketone (PEEK) has emerg...
Titanium-coated ceramic materials with varying roughness and surface topography have been developed and utilized in clinical trials within the realms of medical and dental implantology. The objective of this study was to assess how cellular attachmen...
Exposed dentin is vulnerable to demineralization and hypersensitivity. Bioactive glass (BAG) is incorporated into dental materials to promote apatite deposition, but its effects relative to a BAG-free formulation remain unclear. This study evaluated...
Purpose: The objective of this study was to assess the influence of a novel surface of dental implants (ContacTi®) on the osseointegration process in a minipig model. The surface was compared with other existing surfaces on the market (SLA® a...
In this report, utraviolent (UV) photoionization of cyclopropylamine on silicon (100) hydride was employed to examine interfacing with three different epithelial cell types (MDA-MB 231, AGS and HEC1A). The cellular viability using this novel methodol...
Magnesium alloys are promising biomaterials to be used as temporary implants due to their biocompatibility and biodegradability. The main limitation in the use of these alloys is their rapid biodegradation. Moreover, the risk of microbial infections,...
This study aimed to analyze the enamel remineralization efficacy of a novel fluoridated bioactive glass (F-BG) toothpaste compared to a standard fluoride toothpaste. Seventy-two enamel blocks (N = 72) were divided into groups of twenty-four blocks ac...
The aim of this study was to promote bioactivity of the PEEK surface using sulfuric acid and piranha solution. PEEK was functionalized by a sulfuric acid treatment for 90 s and by piranha solution for 60 and 90 s. Chemical modification of the PEEK su...
To evaluate the impact of different surface treatment regimens, Neodymium-doped yttrium orthovanadate (Nd: YVO4) laser, Toluidine blue (TB) activated Low-level laser therapy (LLLT), and Bioactive glass particles (BAGPs) on the surface roughness (Ra),...
This study prepared composites for core build-up containing Sr/F bioactive glass nanoparticles (Sr/F-BGNPs) and monocalcium phosphate monohydrate (MCPM) to prevent dental caries. The effect of the additives on the physical/mechanical properties of th...
The use of dental implants has grown over the years and has led to higher success rates. To further enhance surgical outcomes, many research groups and companies have shifted their focus to surfaces roughness, wettability and chemistry. In a recent s...
Bioactive glass (BG), a potential biomaterial, has received increasing attention since the discovery of its superior bioactivity. One of the main research objectives is to improve the bioactive property of BGs; therefore, surfactant-derived mesoporou...
The synthetic thermoplastic polymer polyetheretherketone (PEEK) is becoming a popular component of clinical orthopedic and spinal applications, but its practical use suffers from several limitations. Although PEEK is biocompatible, chemically stable,...
The integration of bioactive natural compounds into dental materials has gained increasing attention as a strategy to improve biological functionality while maintaining material performance. This narrative review aims to synthesize current evidence r...
Bone defects caused by trauma or pathological events are major clinical and socioeconomic burdens. Thus, the efforts of regenerative medicine have been focused on the development of non-biodegradable materials resembling bone features. Consequently,...
Microbial contamination represents an undesirable event in various domains. Bioactive natural compounds possess plenty of health benefits, including antimicrobial, antifungal and antioxidative activity; however, they are chemically unstable and susce...
Electrospun nanofibers provide high surface area, interconnected porosity, and extracellular-matrix-like architectures that can be combined with controlled degradation, local therapeutic delivery, and surface biofunctionalization. This review examine...
A wide variety of composite scaffolds with unique geometry, porosity and pore size can be fabricated with versatile 3D printing techniques. In this work, we fabricated 3D-printed composite scaffolds of polycaprolactone (PCL) incorporating bioactive g...
Highly porous 45S5 bioactive glass-based scaffolds were fabricated by the foam replica technique and coated with collagen by a novel method. After an initial cleaning step of the bioactive glass surface to expose reactive –OH groups, samples we...
Bioactive glasses have been used for many years in the human body as bone substitute. Since bioactive glasses are not readily available in the form of endless thin fibres with diameters below 20 µm, their use is limited to mainly non-load-bearing app...
Polyetheretherketone (PEEK) is increasingly attractive for patient-specific maxillofacial reconstruction because its elastic modulus approximates cortical bone, it is fully radiolucent, and it is compatible with additive manufacturing; its principal...
This study presents the development and comprehensive evaluation of magnesium-based implants with surface modifications using selected polymers and bioactive compounds. The implants were fabricated via plasma electrolytic oxidation (PEO), followed by...
A bioactive layer, free of nickel, has been performed for its greater acceptability and reliability in clinical applications for NiTi shape memory alloys. In the first step, a safe barrier against Ni release has been produced on the surface by means...
The bioactive and anti-bacterial Cu-based bioceramic TiO2 coatings have been fabricated on cp-Ti (Grade 2) by two-steps. These two-steps combine micro-arc oxidation (MAO) and physical vapor deposition–thermal evaporation (PVD-TE) techniques for...
Chitosan–hydroxyapatite (CS–HA) composite coatings offer a multifunctional surface modification to improve titanium implant performance, combining hydroxyapatite’s osteoconductivity with chitosan’s biocompatibility and antimicrobial properties. This...
Bioactive glasses are known for their surface reactivity and ability to bond with bone tissue through the formation of hydroxyapatite. This study investigates the effects of substituting ultrapure water with natural geothermal waters from the Azores...
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