Innovative Biomaterials and Advanced Technologies in Bone Tissue Regeneration

A special issue of Bioengineering (ISSN 2306-5354). This special issue belongs to the section "Biomedical Engineering and Biomaterials".

Deadline for manuscript submissions: 1 November 2025 | Viewed by 263

Special Issue Editor

Special Issue Information

Dear Colleagues,

The use of biomaterials in dentistry, maxillofacial surgery, and orthopedics is increasingly important for advancing healthcare. Bone repair and regeneration continue to pose significant clinical challenges, with a growing global demand for more effective solutions. Despite the widespread use of traditional grafting methods, there are limitations related to the availability and quality of transplants. Therefore, there is a growing demand for innovative alternatives, such as natural and synthetic biomaterials, which can act as scaffolds for hard tissue regeneration. Additionally, advancements in implants, prosthetics, and digital dentistry are reshaping functional and aesthetic rehabilitation approaches for patients.

This Special Issue will cover the latest developments in biomaterials, with a focus on their properties, mechanical behaviors, and interactions with cells and tissues. It will also explore their role in osseointegration and the long-term sustainability of implants and prosthetics. State-of-the-art tissue engineering strategies, including the integration of biomaterials with various cell types, growth factors, and extracellular vesicles, will be highlighted to enhance bone tissue regeneration. Moreover, the role of digital tools, including numerical studies and computational simulations, will be emphasized for its contributions to improving implant design and prosthetic performance.

The aim of this Special Issue is to enhance the efficacy, longevity, and precision of medical implants, prosthetics, and bone substitute materials, ultimately improving patient outcomes and quality of life. Original research articles, comprehensive reviews, short communications, and mini-reviews reporting on innovative biomaterials, tissue engineering strategies, implant surface technologies, prosthetic innovations, numerical modeling, and digital workflows are encouraged.

In summary, this collection will explore the development of cutting-edge biomaterials and techniques for improving implant performance, bone regeneration, and prosthetics in dental and orthopedic fields. It aims to promote interdisciplinary collaboration and push the boundaries of current practices, ultimately advancing healthcare solutions for patients worldwide.

Tea Romasco
Guest Editor Assistant
Affiliation: Department of Medical, Oral and Biotechnological Sciences, Center for Advanced Studies and Technology (CAST), “G. d’Annunzio” University of Chieti-Pescara, 66100 Chieti, Italy

Dr. Natalia Di Pietro
Guest Editor

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Keywords

  • biomaterials
  • bone tissue regeneration
  • tissue engineering
  • scaffolds
  • prosthetics
  • dental implants
  • osseointegration
  • numerical studies
  • biomechanics
  • digital dentistry

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Published Papers

This special issue is now open for submission.
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