Substance misuse services need to meet the growing demand and needs of individuals using new psychoactive substances (NPS). A review of the literature identified a paucity of research regarding NPS use by these individuals and UK guidelines outline t...
Background and Objectives: Over the past twenty years a large number of new psychoactive substances (NPS) have entered and modified the recreational drug scene. Their intake has been associated with health-related risks, especially so for vulnerable...
Soil extra-cellular enzymes are the main driving force for microbial and biochemical processes, which makes them sensitive indicators for soil health and quality. Returning large amounts of sludge or its biochar to farmland may introduce exogenous su...
New/novel psychoactive substances (NPS) are defined as new narcotic/psychotropic drugs which are not controlled by the United Nations’ 1961 Narcotic Drugs/1971 Psychotropic Substances conventions, but which may pose a public health threat [...]
Recently, a range of prescription and over-the-counter drugs have been reportedly used as Novel Psychoactive Substances (NPS), due to their potential for abuse resulting from their high dosage/idiosyncratic methods of self-administration. This paper...
Humic substances are organic ubiquitous components arising in the process of chemical and microbiological oxidation, generally called humification, the second largest process of the carbon cycle. The beneficial properties of these various substances...
This paper presents various aspects of the use of chromatography to determine the biological activity of substances. On the one hand, the use of chromatography to determine the lipophilicity of a substance, a property that affects all LADME steps in...
Marine algae have received great attention as natural photoprotective agents due to their unique and exclusive bioactive substances which have been acquired as an adaptation to the extreme marine environment combine with a range of physical parameter...
Freezing is a crucial technology for preserving food quality and extending shelf life. However, frozen storage often leads to protein oxidation, degradation, and cellular structural damage, compromising food palatability. To address these challenges,...
Objective: This survey aimed to explore knowledge and experience on novel psychoactive substances (NPS) of healthcare professionals (HCPs). The study also aimed to assess how HCPs would like to improve their knowledge of NPS. Methods: Seventy paper q...
Exposure to psychoactive substances is undoubtedly a serious public health issue that should be carefully analyzed from different perspectives. Regarding the types of toxic effects inflicted by these xenobiotics, it is already known that many of the...
The paper reviews the patent descriptions of methods for obtaining humic substances and the procedures used in their industrial production. Selected humus substances, obtained using three different methods, were also examined. In the first one, humic...
Landfill leachate contains a range of organic and inorganic pollutants, including per-/polyfluoroalkyl substances (PFASs), which can infiltrate into surrounding soil and groundwater through leaching processes, and can pose a threat to human health vi...
14 January 2022
This study aims to determine prevalence and frequency of use of novel psychoactive substances (NPS) and to identify the factors associated with NPS use in an Italian sample of patients diagnosed with substance use disorder (SUD). Prevalence and corre...
Drug abuse represents a significant public health problem with a growing tendency. As a way of circumventing the strict national and international control of psychoactive substances by regulatory agencies, there is a market release of new substances...
This comprehensive review presents the results of an in-depth analytical literature search on the biological activity of humic substances and their possible pharmacological mechanisms of action. The unique chemical structure of humic substances has d...
Alfalfa is a leguminous plant with strong autotoxicity, which seriously affects regeneration and stability. In order to clarify the relationship between the key autotoxic substances and autotoxicity of alfalfa, this experiment determined the content...
This technical clinical and forensic note is designed to interpret the influence that psychoactive (or psychotropic) substances may have on driving. The present interpretation is restricted to the four groups of substances (i.e., cannabinoids, cocain...
16 January 2021
Introduction: Osteoporosis is a disease having adverse effects on bone health and causing fragility fractures. Osteoporosis affects approximately 200 million people worldwide, and nearly 9 million fractures occur annually. Evidence exists that, in ad...
Knowledge about determinants of addiction in people taking addictive substances is poor and needs to be supplemented. The novelty of this paper consists in the analysis of innovative aspects of current research about relationships between determinant...
As a globally cultivated and economic crop, beets are particularly important in the cane sugar and feed industries. Beet pigments are among the most important natural pigments, while various chemical components in beets display beneficial biological...
This paper systematically investigates psychoactive substances and their ritual consumption practices within the Daoist cultivation tradition. As a category of Daoist ingestive (fushi 服食) culture, these substances, derived either from s...
Introduction: A significant increase in psychoactive drugs use was observed in women of childbearing age and during the perinatal period worldwide. Yet, the use of illicit drugs, alcohol and tobacco during pregnancy is a serious health risk for the m...
Reservoirs in river-lake systems play a dominant role in the circulation of biogenic substances. Their evolutional transformations, consisting in accumulation of substances, results it their ultimate disappearance. However, at a given moment, the rol...
Actual diffusion activity function is an important metric utilized to describe the diffusion activities of a vacancy defect substance. In this paper, we propose a deep learning three-dimensional convolutional CNN model (D3-CNN). A 3D convolution has...
The aim of this study was to assess the associations between HIV status, SARS-CoV-2 infection, increase in use of psychoactive substances and oral ulcers among people who use psychoactive substances. This was a secondary analysis of the data of 1087...
Background: The well-recognized but not fully explored antioxidant activity of marine-biota-derived, biologically active substances has led to interest in their study as substitutes of antibiotics, antiaging agents, anticancer and antiviral drugs, an...
Specific gut microorganisms and their metabolic by-products have been identified as key regulators of host physiology, contributing to the modulation of the immune system, inflammatory processes, brain function, and behavior, which highlights the gut...
Background/Objectives: The homeless population (HP) is a heterogeneous group characterized by the absence of stable and conventional housing, often relying on public spaces and deteriorated environments for shelter and survival, either temporarily or...
7 May 2021
The outbreak of the COVID-19 pandemic and the measures taken for tackling it had the potential to lead to deep modifications in the supply of illegal drugs and to impact substance users’ health and social situation. To investigate this, we used mixed...
Teak (Tectona grandis L.f.) is one of the most valuable timber species, and is cultivated in agroforestry systems in many countries across the tropical and subtropical regions of the world. The species is also one of the most essential trees in home...
Environmental pollution with contaminants of emerging concern (CECs) is a worldwide problem that is receiving increasing attention. Although these substances have been released in the aquatic environment for a long time, wastewater treatment plants a...
17 April 2022
The emergence of new psychoactive substances has earned a great deal of attention, and several reports of acute poisoning and deaths have been issued involving, for instance, synthetic opiates. In recent years, there have been profound alterations in...
Environmental pollution with petroleum products has become a major problem worldwide, and is a consequence of industrial growth. The development of sustainable methods for the removal of petroleum substances and their derivatives from aquatic and ter...
The existence of odors in drainage pipelines is one of the most prominent environmental problems that urban residents complain about nowadays. Odorous substances in sewage can cause corrosion and erosion in drainage pipelines, and even lead to great...
Antioxidative substances constitute the important barrier maintaining the oxidative stability of edible oils against lipid degradation and the formation of harmful aldehydes and ketones. In this study, an oil-compatible non-aqueous electrochemical me...
The review summarizes studies on the detoxification effects of water-soluble humic substances (HS), which are products of the natural transformation of organic substances in soils and bottom sediments that serve as natural detoxifying agents in water...
Species of the genus Artemisia are well known for their use as ingredients in ancient medicine. The advantage of using plant extracts compared to individual pharmaceutical ingredients is the rate of adaptation of the pathogenic microorganisms to the...
The article deals with the removal of humic substances from surface water in the High Tatras locality and with the reduction in the intensity of water coloration. Four different types of granular activated carbon (Norit 1240, WG12, Filtrasorb TL830,...
A taste sensor with lipid/polymer membranes is one of the devices that can evaluate taste objectively. However, the conventional taste sensor cannot measure non-charged bitter substances, such as caffeine contained in coffee, because the taste sensor...
Humic substances (HSs) present in water and wastewater cause fouling of anion exchange resins (AERs), which mainly results in reducing the ion exchange capacity (IEC). In this paper, an attempt was made to investigate fouling of two polystyrene and o...
Sulfated polysaccharides and other polyanions have been promising candidates in antiviral research for decades. These substances gained attention as antivirals when they demonstrated a high inhibitory effect in vitro against human immunodeficiency vi...
The effect of humic substances on growth performance, excretion, and the digestive organs was studied in pheasant chickens. Three hundred 1-day-old pheasant chicks were assigned to two equal groups. Chicks in the experimental group were fed diets sup...
Baijiu is the national liquor of China, which has lasted in China for more than 2000 years. Abundant raw materials, multi-strain co-fermentation, and complex processes make the secrets of baijiu flavor and taste still not fully explored. Acid substan...
The concept of being readily biodegradable is crucial in evaluating the potential effects of chemical substances on ecosystems and conducting environmental risk assessments. Substances that readily biodegrade are generally associated with lower envir...
Malus hupehensis (MH), as a natural resource, contains various active ingredients such as polyphenols, polysaccharides, proteins, amino acids, volatile substances, and other components. Increasingly, studies have indicated that MH showed a variety of...
The phytotoxic potential of plants and their constituents against other plants is being increasingly investigated as a possible alternative to synthetic herbicides to control weeds in crop fields. In this study, we explored the phytotoxicity and phyt...
Naturally occurring psychoactive substances, such as opioids, cocaine, and cannabinoids, affect not only the central nervous system but also the functioning of the microbiota–gut–brain axis. Available evidence indicates that their use is...
Atherosclerosis is the primary pathological foundation of various cardiovascular and cerebrovascular diseases. Although existing treatment strategies exhibit certain efficacy, they still encounter limitations such as pronounced side effects and a sin...
The aim of this study was to determine the prevalence of addictive substance use among students during one-year period, to evaluate the present situation, and to substantiate the necessity of prevention.
Material and methods. The participants of the...
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