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53,163 Results Found

  • Article
  • Open Access
14 Citations
4,610 Views
15 Pages

Functional and Structural Features of Disease-Related Protein Variants

  • Castrense Savojardo,
  • Giulia Babbi,
  • Pier Luigi Martelli and
  • Rita Casadio

Modern sequencing technologies provide an unprecedented amount of data of single-nucleotide variations occurring in coding regions and leading to changes in the expressed protein sequences. A significant fraction of these single-residue variations is...

(This article belongs to the Special Issue Biophysics of Human Genetic Diseases: Understanding Molecular Effects of Mutations)
  • Article
  • Open Access
1 Citations
3,356 Views
14 Pages

Structural reliability and structural robustness, from different research fields, are usually employed for the evaluative analysis of building and civil engineering structures. Structural reliability has been widely used for structural analysis and o...

(This article belongs to the Special Issue Mathematical and Computational Modelling in Mechanics of Materials and Structures)
  • Article
  • Open Access
93 Views
26 Pages

11 November 2026

Knowledge graphs (KGs) support knowledge organization and reasoning throughout the home appliance manufacturing lifecycle, but missing relations limit their use in downstream applications. To improve relation completion under sparse data conditions,...

(This article belongs to the Section Advanced Manufacturing)
  • Article
  • Open Access
3 Citations
2,448 Views
10 Pages

26 November 2021

The structure evolution of nuclei which are in connection with symmetry breaking is one of the important problems not only for nuclear structures, but also for astrophysics and the spectroscopy of exotic nuclei. Many physical quantities can provide u...

(This article belongs to the Special Issue Experiments and Theories of Radioactive Nuclear Beam Physics)
  • Article
  • Open Access
2 Citations
1,594 Views
12 Pages

14 August 2024

In knowledge structure theory (KST), an individual’s knowledge state represents the items that the individual can completely solve. Based on the differences in individuals’ latent cognitive competence, polytomous knowledge states can be u...

(This article belongs to the Topic Adversarial Machine Learning: Theories and Applications)
  • Review
  • Open Access
26 Citations
6,837 Views
34 Pages

23 August 2021

Pristine graphene is one of the strongest materials known in the world, and may play important roles in structural and functional materials. In order to utilize the extraordinary mechanical properties in practical engineering structures, graphene sho...

(This article belongs to the Special Issue Structure, Function and Mechanics of Low-Dimensional Materials and Their Assemblies)
  • Article
  • Open Access
55 Views
29 Pages

Relational Structure of Color Organization in a Free Color Arrangement Task

  • Teo Žeželj,
  • Mile Matijević,
  • Krunoslav Hajdek and
  • Marko Morić

12 November 2026

Color organization in visual communication depends not only on individual colors but also on relationships within complete color sets. However, whether freely generated relational structures are shared across individuals and vary with residential env...

(This article belongs to the Special Issue Advances in Visibility and User Experience in Visual Design)
  • Article
  • Open Access
1 Citations
1,672 Views
16 Pages

12 January 2026

Despite the growing role of business incubators in fostering digital startups in emerging economies, the mechanism through which business incubator characteristics, specifically relational capital and structural embeddedness, influence startup innova...

(This article belongs to the Special Issue Catalyzing Growth: Nurturing Innovation and Entrepreneurship for Sustainable Business Development)
  • Review
  • Open Access
10 Citations
3,122 Views
43 Pages

Microalgae-Derived Peptides Targeting Lifestyle-Related Diseases: Discovery, Mechanisms, Structure–Activity Relationships, and Structural Modifications

  • Mohammed S. Qoms,
  • Sok Kuan Wong,
  • Norsyahida Mohd Fauzi,
  • Khairana Husain and ,
  • Suzana Makpol and
  • Jen Kit Tan
  • + 1 author+ 0 author

25 September 2025

Microalgae are an emerging source of bioactive peptides with promising therapeutic potential against lifestyle-related diseases such as oxidative stress-related conditions, hypertension, diabetes, and obesity. While numerous studies have investigated...

  • Article
  • Open Access
1 Citations
2,187 Views
10 Pages

29 July 2023

In terms of the comprehension of modern order and values, understanding individuals and their relationship with the community has always been an important perspective. Scholars have noticed that traditional Confucian thought in China contains a profo...

(This article belongs to the Special Issue Discussing the Relationship between Individual and Community: From the Perspective of Confucianism)
  • Article
  • Open Access
108 Citations
16,582 Views
18 Pages

Chemical Structure-Related Drug-Like Criteria of Global Approved Drugs

  • Fei Mao,
  • Wei Ni,
  • Xiang Xu,
  • Hui Wang and ,
  • Jing Wang,
  • Min Ji and
  • Jian Li
  • + 2 authors+ 0 author

12 January 2016

The chemical structure of a drug determines its physicochemical properties, further determines its ADME/Tox properties, and ultimately affects its pharmacological activity. Medicinal chemists can regulate the pharmacological activity of drug molecule...

(This article belongs to the Special Issue Drug Design and Discovery: Principles and Applications)
  • Article
  • Open Access
3 Citations
3,457 Views
24 Pages

13 August 2024

The structure of the network among firms participating in global value chains is an important factor in understanding the changes in China’s carbon emissions. This paper focuses on the interdependence between firms and the interconnected networ...

(This article belongs to the Special Issue Environmental Economics in Sustainable Social Policy Development)
  • Article
  • Open Access
3 Citations
3,548 Views
20 Pages

Many new antimicrobials are analogs of existing drugs, sharing the same targets and mechanisms of action. New antibiotic targets are critically needed to combat the growing threat of antimicrobial-resistant bacteria. Phage-related ribosomal proteases...

(This article belongs to the Special Issue Antimicrobial Resistance and Virulence – 3rd Volume)
  • Article
  • Open Access
12 Citations
3,989 Views
20 Pages

5 September 2020

Modern features of the development of the agro-industrial complex as part of the economy as a whole require changes in the traditional models of state regulation, which do not take into account the structure of rental income in the economy and do not...

(This article belongs to the Special Issue New Approaches to Evaluation and Measurement of Sustainability and Its Relationship with Other Areas (Directions) of World Development)
  • Article
  • Open Access
1 Citations
704 Views
23 Pages

From Shocks to Structure: Climate-Related Losses, Fiscal Sustainability, and Risk Governance in Europe

  • Dariusz Sala,
  • Oksana Liashenko,
  • Kostiantyn Pavlov,
  • Olena Pavlova and ,
  • Roman Romaniuk,
  • Igor Kotsan and
  • Michał Pyzalski
  • + 2 authors+ 0 author

24 March 2026

Climate-related economic losses across Europe have evolved from isolated environmental shocks to persistent, structurally embedded fiscal risks, posing a direct challenge to the long-term fiscal sustainability of European states. This study presents...

(This article belongs to the Special Issue Effectiveness Evaluation of Sustainable Climate Policies)
  • Article
  • Open Access
90 Citations
8,718 Views
12 Pages

The in Vitro Structure-Related Anti-Cancer Activity of Ginsenosides and Their Derivatives

  • Hang Dong,
  • Li-Ping Bai,
  • Vincent Kam Wai Wong,
  • Hua Zhou and ,
  • Jing-Rong Wang,
  • Yan Liu,
  • Zhi-Hong Jiang and
  • Liang Liu
  • + 3 authors+ 0 author

19 December 2011

Panax ginseng has long been used in Asia as a herbal medicine for the prevention and treatment of various diseases, including cancer. The current study evaluated the cytotoxic potency against a variety of cancer cells by using ginseng ethanol extract...

  • Article
  • Open Access
26 Citations
3,395 Views
11 Pages

Study of Concrete Strength and Pore Structure Model Based on Grey Relation Entropy

  • Min Zhang,
  • Xianhua Yao,
  • Junfeng Guan,
  • Lielie Li and ,
  • Juan Wang and
  • Longbang Qing
  • + 1 author+ 0 author

16 January 2021

The Grey Relation Entropy (GRE) theory is used to analyze the sensitive pore size that affects the compressive strength of concrete. The relationship between the strength and pore structure is revised based on the sensitivity coefficient. The revised...

  • Article
  • Open Access
159 Views
35 Pages

1 November 2026

Climate-related development finance is expected to support low-carbon investment, technological diffusion, and economic adjustment, yet it remains unclear whether these processes translate into broader structural transformation. This paper examines a...

(This article belongs to the Special Issue Climate Finance, Technological Change, and Labor Market Transformation in Developing Economies)
  • Article
  • Open Access
1 Citations
1,790 Views
17 Pages

24 June 2024

An extended hybrid method for the analysis of the symmetric structural behavior of segmental tunnel linings is proposed. Their deformations cannot be determined by the traditional hybrid methods when the convergences are close to the serviceability l...

(This article belongs to the Section Civil Engineering)
  • Article
  • Open Access
19 Citations
7,066 Views
25 Pages

Selected Compounds Structurally Related to Acyclic Sesquiterpenoids and Their Antibacterial and Cytotoxic Activity

  • Radosław Bonikowski,
  • Paulina Świtakowska,
  • Monika Sienkiewicz and
  • Małgorzata Zakłos-Szyda

18 June 2015

By implementing a common and industrially used method, 30 compounds which are structurally related to geranyl acetone, nerolidol, farnesal, farnesol and farnesyl acetate were obtained. Their antimicrobial activity against Staphylococcus aureus, Enter...

(This article belongs to the Section Organic Chemistry)
  • Article
  • Open Access
2,070 Views
21 Pages

13 December 2023

Nuclear safety-related structures are crucial for ensuring the safety of nuclear facilities and preventing the leakage of radioactive materials, with the primary structural component being low-rise reinforced concrete (LRC) walls. These walls are req...

(This article belongs to the Section Building Structures)
  • Article
  • Open Access
2 Citations
3,102 Views
23 Pages

10 October 2023

Since entering the period of economic and social transformation, China’s labor relations conflicts have entered a period of prominence and prevalence, which has brought great challenges to ensure the sustainable development of enterprises and b...

(This article belongs to the Section Health, Well-Being and Sustainability)
  • Article
  • Open Access
28 Citations
6,915 Views
24 Pages

21 April 2020

To systematically analyze energy-related carbon emissions from the perspective of comprehensive energy flow and allocate emissions responsibility, we introduce energy allocation analysis to carbon flow process based on Sankey diagrams. Then, to quant...

(This article belongs to the Special Issue Selected Papers from PRES’19: The 22nd Conference on Process Integration, Modelling and Optimisation for Energy Saving and Pollution Reduction)
  • Article
  • Open Access
466 Views
30 Pages

A Weighted Relational Graph Model for Emergent Superconducting-like Regimes: Gibbs Structure, Percolation, and Phase Coherence

  • Bianca Brumă,
  • Călin Gheorghe Buzea,
  • Diana Mirilă,
  • Valentin Nedeff and ,
  • Florin Nedeff,
  • Maricel Agop,
  • Ioan Gabriel Sandu and
  • Decebal Vasincu
  • + 3 authors+ 0 author

25 April 2026

We introduce a minimal relational network model in which superconducting-like behavior emerges as a collective phase of constrained connectivity and phase coherence, without assuming microscopic electrons, phonons, or material-specific interactions....

(This article belongs to the Section Mathematical Physics)
  • Article
  • Open Access
3 Citations
7,439 Views
22 Pages

Toward a Consensus Model of Cognitive–Reading Achievement Relations Using Meta-Structural Equation Modeling

  • Daniel B. Hajovsky,
  • Christopher R. Niileksela,
  • Dawn P. Flanagan,
  • Vincent C. Alfonso and ,
  • William Joel Schneider and
  • Jacob Robbins
  • + 1 author+ 0 author

Cognitive tests measure psychological constructs that predict the development of academic skills. Research on cognitive–reading achievement relations has primarily been completed with single-test batteries and samples, resulting in inconsistenc...

(This article belongs to the Special Issue Intelligence Testing and Assessment)
  • Article
  • Open Access
32 Citations
6,782 Views
20 Pages

8 March 2020

The retention of structural elements such as habitat trees in forests managed for timber production is essential for fulfilling the objectives of biodiversity conservation. This paper seeks to predict tree-related microhabitats (TreMs) by close-range...

(This article belongs to the Special Issue 3D Forest Structure Observation)
  • Article
  • Open Access
3 Citations
2,265 Views
17 Pages

29 April 2023

This study proposed a procedure of using the energy method to evaluate the SSI-related damping effect when the soil–structure interaction (SSI) was considered in a bridge pier system, which can thus be deemed a soil–foundation–super...

(This article belongs to the Special Issue Intelligent Solutions for the Sustainability of Bridges and Structures)
  • Article
  • Open Access
6 Citations
1,798 Views
18 Pages

Study on Water Resource Carrying Capacity and Crop Structure Optimization Based on Gray Relational Analysis

  • Lingyun Xu,
  • Bing Xu,
  • Ruizhong Gao,
  • Guoshuai Wang and ,
  • Delong Tian,
  • Yuchao Chen,
  • Jie Zhou,
  • Xiangyang Miao and
  • Pingxia Wang
  • + 4 authors+ 0 author

23 February 2025

This study addresses challenges such as insufficient irrigation water quotas, severe groundwater over-extraction, and conflicts around crop water usage within the mixed-cropping areas of the Inner Mongolia Yellow River Basin. Five evaluation factors&...

(This article belongs to the Section Crop Physiology and Crop Production)
  • Article
  • Open Access
8 Citations
5,804 Views
28 Pages

17 June 2019

Nucleosome Assembly Protein (NAP) is a highly conserved family of histone chaperones present in yeast, animals, and plants. Unlike other organisms, plants possess an additional class of proteins in its NAP family, known as the NAP1-related proteins o...

(This article belongs to the Special Issue Frontier of Protein Crystallography)
  • Article
  • Open Access
13 Citations
7,358 Views
20 Pages

11 October 2022

Many professionals from several disciplines need to cooperate in designing and constructing tall buildings since their design and construction require more complex systems and technologies in terms of structure, installation, facade, vertical circula...

(This article belongs to the Topic Architectures, Materials and Urban Design)
  • Article
  • Open Access
18 Citations
3,481 Views
25 Pages

10 October 2022

Nowadays, electricity theft has been a major problem worldwide. Although many single-classification algorithms or an ensemble of single learners (i.e., homogeneous ensemble learning) have proven able to automatically identify suspicious customers in...

(This article belongs to the Special Issue Application of Artificial Intelligence in Power System Monitoring and Fault Diagnosis)
  • Article
  • Open Access
600 Views
31 Pages

22 April 2026

This study evaluated whether membrane structures can enhance thermal comfort and reduce heat- and cold-related health risks in privately owned public spaces (POPS) under representative seasonal peak conditions. Based on previous in situ measurements...

(This article belongs to the Special Issue Sustainable Urban Risk Management and Resilience Strategy)
  • Article
  • Open Access
14 Citations
5,577 Views
15 Pages

12 May 2018

With the economic development, the demand for water resources has been increasing dramatically during the last several decades. The sustainable development of water resources has become a major challenge in our society. As the largest economic center...

(This article belongs to the Special Issue Transition from China-Made to China-Innovation )
  • Article
  • Open Access
10 Citations
3,933 Views
20 Pages

16 March 2023

Relation extraction, a fundamental task in natural language processing, aims to extract entity triples from unstructured data. These triples can then be used to build a knowledge graph. Recently, pre-training models that have learned prior semantic a...

(This article belongs to the Special Issue New Machine Learning and Deep Learning Techniques in Natural Language Processing)
  • Article
  • Open Access
31 Citations
5,095 Views
20 Pages

27 February 2020

In a context of widespread acceptance and implementation of the United Nations Sustainable Development Goals (SDGs), this paper discusses the possible relationship between intellectual capital (IC) and nonfinancial information (NFI), particularly rel...

(This article belongs to the Special Issue Achieving Sustainable Development Goals (SDGs) among Walking and Talking)
  • Article
  • Open Access
1,984 Views
20 Pages

20 December 2024

By combining molecular dynamics (MD) simulations and density functional theory (DFT), the influence of dye structure on the optical modulation properties of negative-mode guest–host liquid crystal (GHLC) systems was systematically investigated....

  • Article
  • Open Access
1,263 Views
27 Pages

Ancestral BG1 Alleles and Structural Conservation Ensure Immune-Related Genetic Resilience in Southeast Asian Chicken Lineages

  • Anh Huynh Luu,
  • Trifan Budi,
  • Worapong Singchat,
  • Chien Tran Phuoc Nguyen and ,
  • Thitipong Panthum,
  • Nivit Tanglertpaibul,
  • Kanithaporn Vangnai,
  • Aingorn Chaiyes,
  • Chotika Yokthongwattana and
  • Kornsorn Srikulnath
  • + 12 authors+ 7 authors

3 May 2026

Chicken (Gallus gallus domesticus) domestication, likely associated with dry-rice farming in central Thailand, has led to substantial loss of ancestral immune-related genetic diversity in commercial chicken lineages. This study addresses allelic loss...

(This article belongs to the Section Animal Genetics and Genomics)
  • Article
  • Open Access
3 Citations
2,163 Views
11 Pages

Tooth Loss, Nutrition, and Oral Health-Related Quality of Life in Older Adults: Evidence from a Structural Equation Model

  • Beatriz Della Terra Mouco Garrido,
  • Patrícia Soares Silva Pereira,
  • Kamilly Foloni,
  • Heloisa Dalberto Pegoraro and ,
  • Isabelle Roldão Souza,
  • José Roberto Magalhães Bastos,
  • Gerson Aparecido Foratori-Júnior,
  • Monica Yamauti,
  • Raquel Conceição Ferreira and
  • Roosevelt Silva Bastos
  • + 5 authors+ 0 author

Background: Oral health problems, particularly tooth loss, may impair nutrition and reduce oral health-related quality of life (OHRQoL) in older adults. However, the pathways linking these conditions remain unclear. Methods: We analyzed data from 112...

(This article belongs to the Section Global Health)
  • Article
  • Open Access
15 Citations
4,142 Views
11 Pages

Analysis of Non-Structural Carbohydrate in Relation with Shoot Elongation of Rice under Complete Submergence

  • Arinal Haq Izzawati Nurrahma,
  • Shin Yabuta,
  • Ahmad Junaedi and
  • Jun-Ichi Sakagami

12 January 2021

Regulation of non-structural carbohydrates (NSCs) are important for plants in response to submergence. In this study, the difference in non-structural carbohydrates in relation with shoot elongation between Sub1A and non-Sub1A rice genotypes was inve...

(This article belongs to the Special Issue Sustainable Tropical Crop Science and Agriculture Management)
  • Article
  • Open Access
2 Citations
3,836 Views
12 Pages

19 March 2024

There has been an interest in understanding the relationship between textile cotton fiber strength (or tenacity) and structure for better fiber quality measurement and enhancement. This study utilized coupled Stelometer and high volume instrument (HV...

  • Article
  • Open Access
11 Citations
8,494 Views
18 Pages

11 January 2023

Pauses act as important acoustic cues to prosodic phrase boundaries. However, the distribution and phonetic characteristics of pauses have not yet been fully described either cross-linguistically or in different genres and speech styles within langua...

(This article belongs to the Special Issue Pauses in Speech)
  • Article
  • Open Access
163 Views
23 Pages

Enhancing Question Representation for Knowledge Tracing via Adaptive Concept Relation Discovery and Structural–Semantic Co-Optimization

  • Zhigang Sun,
  • Lixin Tian,
  • Yifeng Zhu,
  • Qiuxia Gong and ,
  • Li-E Wang and
  • Wei Wang
  • + 1 author+ 0 author

15 October 2026

Knowledge tracing (KT) models the evolution of students’ knowledge states from historical learning interactions, serving as a fundamental mechanism for intelligent educational systems. The efficacy of KT models heavily relies on the quality of...

(This article belongs to the Section Artificial Intelligence)
  • Article
  • Open Access
418 Views
27 Pages

Knowledge graph link prediction is a fundamental task for improving the completeness and reasoning capability of knowledge graphs. In industrial knowledge graph scenarios, missing relations may limit knowledge completion, relational reasoning, and do...

(This article belongs to the Section Artificial Intelligence)
  • Article
  • Open Access
40 Citations
6,000 Views
23 Pages

Modeling the Relation between Building Information Modeling and the Success of Construction Projects: A Structural-Equation-Modeling Approach

  • Ahsan Waqar,
  • Idris Othman,
  • Dorin Radu,
  • Zulfiqar Ali and ,
  • Hamad Almujibah,
  • Marijana Hadzima-Nyarko and
  • Muhammad Basit Khan
  • + 2 authors+ 0 author

7 August 2023

Over the course of the last twenty years, building information modeling (BIM) has emerged as a firmly established construction methodology integrating fundamental principles. The implementation of BIM methodologies possesses the capability to augment...

(This article belongs to the Special Issue Advances in BIM-Based Architectural Design and System)
  • Article
  • Open Access
9 Citations
2,993 Views
10 Pages

12 August 2021

Single crystals of new non-centrosymmetric iodate Ba(IO3)OH are synthesized hydrothermally and structurally investigated. OD topology-symmetry analysis of layers and their alternation led to conclusions about the similarity with the Bi(IO3)O nonlinea...

(This article belongs to the Section D: Chemistry: Symmetry/Asymmetry)
  • Article
  • Open Access
1,438 Views
16 Pages

Quantum mechanics is among the most successful physical theories, yet its formulation and empirical testing rely on classical structures. Following Lev Landau and Niels Bohr, this reliance is not merely pragmatic: quantum observables acquire empirica...

(This article belongs to the Special Issue Quantum Theory 100 Years Later: Advances on Foundations and Applications)
  • Article
  • Open Access
26 Citations
5,176 Views
27 Pages

Modified Rhamnogalacturonan-Rich Apple Pectin-Derived Structures: The Relation between Their Structural Characteristics and Emulsifying and Emulsion-Stabilizing Properties

  • Jessika N. Humerez-Flores,
  • Sarah H. E. Verkempinck,
  • Clare Kyomugasho,
  • Paula Moldenaers and ,
  • Ann M. Van Loey and
  • Marc E. Hendrickx
  • + 1 author+ 0 author

8 July 2021

In the context of the increasing interest in natural food ingredients, the emulsifying and emulsion-stabilizing properties of three rhamnogalacturonan-rich apple pectin-derived samples were assessed by evaluating a range of physicochemical properties...

(This article belongs to the Section Food Physics and (Bio)Chemistry)
  • Article
  • Open Access
3 Citations
2,598 Views
16 Pages

Quantifying the Relation between Activity Pattern Complexity and Car Use Using a Partial Least Square Structural Equation Model

  • François Sprumont,
  • Ariane Scheffer,
  • Geoffrey Caruso,
  • Eric Cornelis and
  • Francesco Viti

24 September 2022

This paper studies the relationship between activity pattern complexity and car use using two multi-day surveys involving the same participants but collected just before and about one year after they relocated their workplace. Measurable characterist...

  • Article
  • Open Access
1,645 Views
26 Pages

Street-view imagery supports fine-grained urban monitoring, but most street-scene change detection methods are pixel-centric or object-centric and cannot explicitly capture the evolution of inter-entity spatial relations needed for interpretable task...

(This article belongs to the Topic Digital and Intelligent Technologies and Application in Urban Construction, Operation, Maintenance, and Renewal)
  • Article
  • Open Access
2 Citations
647 Views
28 Pages

17 July 2026

Geometry is typically treated as a primitive background structure within which physical processes unfold. In this work, we investigate an alternative possibility: that geometry can arise as a structural consequence of relational dynamics. We study th...

(This article belongs to the Section Mathematical Physics)

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