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Special Issue "Frontier of Protein Crystallography"
Deadline for manuscript submissions: closed (31 July 2019).
Prof. Dr. Silvano Geremia
CEB Centre of Excellence in Biocrystallography, Department of Chemical and Pharmaceutical Sciences, University of Trieste, Via L. Giorgieri 1, Trieste, Italy
Interests: crystallography; structural biology; vitamin B12 proteins; redox-proteins; drug delivery; diagnostics; metals in medicine; bioinorganic chemistry; supramolecular chemistry; nanostructures
Structural biology is a relatively young science, initiated about 60 years ago with the elucidation of the first three-dimensional crystal structure of myoglobin. Protein crystallography continues to develop vigorously and today there are over 120,000 structures deposited at the Protein Data Bank (PDB), 90% of which are from X-ray data. The technological developments behind this rapid growth involves all crucial steps of the pipeline “from gene to structure”: from the developments of wet lab technologies, including recombinant DNA techniques, protein purification and crystallization; to innovative hardware technology, for example brilliant light sources such as synchrotrons and X-ray free electron lasers (XFEL) together with high-frame-rate and ultra-sensitive detectors. An important impetus to protein crystallography has also been provided by soft technology: theoretical foundations, computational algorithm, and software development. The bio-crystallography integrated with cryo-electron microscopy is a major research trend in structural biology and the present Special Issue is aimed at covering frontier technologies and methodologies in protein crystallography, as well as their novel applications.
Prof. Dr. Silvano Geremia
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All papers will be peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Molecules is an international peer-reviewed open access semimonthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 1800 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
- X-ray crystallography
- recombinant protein overexpression
- protein purification
- protein crystallization
- radiation sources
- X-ray detectors
- structural biology software
- high-throughput crystallography
- structural biology