Background/Objectives: Downy mildew, caused by Peronosclerospora and Sclerophthora species, is a major constraint to maize production in tropical and subtropical regions, with yield losses of 30–100%. This systematic review synthesised evidence...
This paper addresses the challenge of identifying causes for functional dynamic targets, which are functions of various variables over time. We develop screening and local learning methods to learn the direct causes of the target, as well as all indi...
Worldwide, the green rot caused by Penicillium digitatum is one of the most aggressive postharvest diseases of lemons. Searching for sustainable alternatives to chemical fungicides, epiphytic yeasts as potential biocontrol agents were isolated from c...
Aptamers are nucleic acid sequences that specifically bind with target molecules and are vital to applications such as biosensing, drug development, disease diagnostics, etc. The traditional selection procedure of aptamers is based on the Systematic...
Systemic sclerosis (SSc) is an immuno-inflammatory rheumatic disease that can affect both the skin and internal organs through fibrosis. Pulmonary arterial hypertension (PAH) is one of the most severe secondary complications. Structural changes in th...
Bacteriophages are increasingly investigated as tools for studying and manipulating microbial communities in cattle. However, phage isolation remains challenging because of host specificity, microbial ecosystem differences, and the lack of optimized...
Sickle cell disease (SCD) and other hemoglobinopathies are a major health concern with a high burden of disease worldwide. Since the implementation of newborn screening (NBS) for SCD and other hemoglobinopathies in several regions of the world, techn...
Virtual screening (VS) is an outstanding cornerstone in the drug discovery pipeline. A variety of computational approaches, which are generally classified as ligand-based (LB) and structure-based (SB) techniques, exploit key structural and physicoche...
Background: Access to cancer screening services is crucial for early detection and improved survival rates, yet older adults in Saudi Arabia face significant barriers. Recent data from the Saudi Health Ministry indicate that cancer incidence in this...
Pesticides have been extensively used in agriculture to protect crops and enhance their yields, indicating the need to monitor for their toxic residues in foodstuff. To achieve that, chromatographic methods coupled to mass spectrometry is the common...
Deep learning for glaucoma screening often relies on high-resolution clinical images and convolutional neural networks (CNNs). However, these methods face significant performance drops when applied to noisy, low-resolution images from portable device...
The Hippo pathway controls organ size and homeostasis and is linked to numerous diseases, including cancer. The transcriptional enhanced associate domain (TEAD) family of transcription factors acts as a receptor for downstream effectors, namely yes-a...
Heavy-oil reservoirs exhibit a high water–oil mobility ratio. During cyclic steam stimulation or water flooding in the later stages, severe fingering occurs, making it difficult to produce the remaining oil. Chemical flooding methods such as po...
The thyroid gland, which is sensitive to electromagnetic radiation, plays a crucial role in the regulation of the hormonal levels of the human body. Biosensors, on the other hand, are essential to access information and derive metrics about the condi...
Phosphodiesterases (PDEs), a superfamily of enzymes that hydrolyze cyclic adenosine monophosphate (cAMP) and cyclic guanosine monophosphate (cGMP), are recognized as a therapeutic target for various diseases. However, the current screening methods fo...
In contemporary narrative filmmaking, emerging technologies such as virtual production and generative artificial intelligence are impacting production workflows. Yet one central element of the practice remains unchanged: filmmakers seek to create rel...
Background: The World Health Organisation reports that melanoma had an incidence of 331,722 cases worldwide in 2022, ranking it 17th on the list of the most prevalent malignancies. This disease is a threat to public health as years of potential life...
Screening is a key operation in a crushing plant that ensures adequate product quality of aggregates in mineral processing. The screening process can be divided into the two sub-processes of stratification and passage. The stratification process is a...
Proficiency testing (PT) is an important tool for evaluation of the competences of laboratories which test milk for residues of antimicrobial substances. It also warrants the reliability of the obtained test results, which is important to the clients...
Citrus Huanglongbing (HLB) is one of the most destructive diseases in the citrus industry. At present, Candidatus Liberibacter asiaticus (CLas) cannot be cultured in vitro, and there is a lack of rapid methods to test antibacterial activity, which gr...
Background: This study aimed to enhance the scope of neonatal congenital heart disease (CHD) screening by evaluating the effectiveness of training personnel in CHD screening using the “dual-index” method, combining pulse oximetry with car...
The role and potential impact of digital screen technology in the lives of children is heavily debated. Current evidence is limited by the weakness of measures typically used to characterise screen use, predominantly proxy- or self-reports with known...
Neonatal ophthalmic screening should lead to early diagnosis of ocular abnormalities to reduce long-term visual impairment in selected diseases. If a treatable pathology is diagnosed within a few days after the birth, adequate therapy may be indicate...
The flip-flow vibrating screen (FFVS) is a novel multi-body screening equipment that utilizes vibrations to classify bulk materials in the field of screening machinery. The relative amplitude of FFVSs determines the tension and ejection intensity of...
Methods for woody plant herbicide screening were assayed with the goal of reducing resources and time required to conduct preliminary screenings for new products. Rapid screening methods tested included greenhouse seedling screening, germinal screeni...
5 January 2023
(1) Background: Hypertension (HT) is the most common chronic condition, affecting approximately 1.13 billion people worldwide. Despite freely available blood pressure (BP) devices in primary care (PC) clinics, many patients do not regularly screen fo...
The results of studying the morphological peculiarities of polycrystalline CdS1−xSex films, obtained by screen printing, with well-formed grain boundaries of high structural quality are presented here. The developed method for screen printing provide...
The study assessed the effect of ion nitriding on the properties of the surface layer of Grade 5 titanium alloy used, among others, in medicine. Titanium and its alloys have low hardness and insufficient wear resistance in conditions of friction whic...
Bopu powder® and Sangrovit® were developed from Macleayacordata and are widely used in agriculture and animal husbandry, but their impurities have been rarely reported in the literature. Impurity analysis is of great importance to the quality and saf...
This research explores discrete element method analysis to investigate the wear of NiTi Sand Screens in comparison to traditional materials. The study utilized Altair EDEM v2022.2 software and employed Oka and Archard models to simulate the wear beha...
Newborn screening for lysosomal storage diseases (LSDs) is increasingly being considered as an option. The development of analytical screening methods, of second-tier methods, and of therapeutic possibilities, are paving the way for routine screening...
Aiming at the problems of big noise, lots of false targets, and accurate time extraction while tracking a flying target in the signal from a sky screen sensor, a flying target recognition and time extraction method is proposed, based on wavelet trans...
Several studies have reported the waning effectiveness of COVID-19 vaccines. This study aims to demonstrate the applicability of the screening method for estimating vaccine effectiveness (VE) in a pandemic. We report VE in Hungary, estimated with the...
22 June 2018
Americans fill upward of four billion prescriptions for pharmaceuticals each year, and many of those pharmaceuticals eventually make their way into the environment. Hundreds of different active pharmaceutical ingredients (APIs) are detected in ambien...
Drug development is one of the most significant processes in the pharmaceutical industry. Various computational methods have dramatically reduced the time and cost of drug discovery. In this review, we firstly discussed roles of multiscale biomolecul...
Recent decades have seen a surge in corporate sustainability reports (SRs); their proliferation, however, does not ensure effective and consistent reporting on materiality. To improve the completeness, consistency and uniformity of SRs, this study ai...
This work introduces a novel temperature-triggered threshold voltage shift (T3VS) method to study the energy-dependent
The double-deck vibrating flip-flow screen (DDVFFS) resolves the limitation of the traditional single-deck vibrating flip-flow screen, which cannot perform multi-granularity screening. The nonlinear characteristics of the springs in the DDVFFS lead t...
Bitter orange, Citrus aurantium L. var. amara (CAVA), is an important crop and its flowers and fruits are widely used in China as a food spice, as well as in traditional Chinese medicine, due to its health-promoting properties. The secondary metaboli...
The presence of residues of antimicrobial substances in milk has been an important hygienic and technological parameter of raw milk quality since the 1960s. The presented review focuses on screening methods (microbiological inhibition methods and rap...
Hearing loss is commonly encountered by general practitioners. We aimed to evaluate the screening benefit of air conduction pure-tone audiometry over visual analogue scale (VAS) scores for hearing loss. Moreover, we intended to perform the first cros...
Liquid sloshing is a common phenomenon in ocean engineering, and one which not only affects the stability of ship navigation, but also poses a threat to both the marine environment and human life. Ascertaining how best to reduce the amplitude of liqu...
The successful implementation of carbon dioxide-enhanced oil recovery (CO2-EOR) is crucial in increasing oil production and reducing carbon emissions. For this reason, screening criteria are needed for the initial characterization of a suitable CO2-E...
The continuous emergence of New Psychoactive Substances (NPS) poses a significant challenge to public health and forensic toxicology due to their unpredictable pharmacology and rapid turnover on the illicit market. This study describes the developmen...
Computer-aided drug design techniques are today largely applied in medicinal chemistry. In particular, receptor-based virtual screening (VS) studies, in which molecular docking represents the gold standard in silico approach, constitute a powerful st...
We aimed to determine the most appropriate sarcopenia screening method for Asian populations. We retrospectively studied the physiological differences between the sexes in healthy individuals and prospectively compared using skeletal muscle mass vers...
Non-targeted methods (NTMs) using matrix-assisted laser desorption/ionization time-of-flight mass spectrometry (MALDI-TOF MS) show promise in bacterial resistance detection, yet temporal variations in spectral features pose significant challenges. Th...
An improved system for measuring antioxidant activity via thiobarbituric acid reactive substances and ferric thiocyanate assays is reported, on the basis of oxidation of a linoleic acid (LA) emulsion. Oxidation times were reduced from 20 h to 5 h by...
Isovaleric aciduria (IVA) is a rare disorder of leucine metabolism and part of newborn screening (NBS) programs worldwide. However, NBS for IVA is hampered by, first, the increased birth prevalence due to the identification of individuals with an att...
Background/Objectives: Non-invasive prenatal testing (NIPT) has become a widely used method for screening common fetal aneuploidies due to its high sensitivity and specificity compared to traditional screening methods. With various NIPT technologies...
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