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Antibiotics
Special Issues
Emerging Challenges in Food Safety: Addressing Antimicrobial Resistance, Virulence Factors,...
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Emerging Challenges in Food Safety: Addressing Antimicrobial Resistance, Virulence Factors, and Biofilm Formation in Food-Borne Pathogens

A special issue of Antibiotics (ISSN 2079-6382).

Deadline for manuscript submissions: 31 March 2025 | Viewed by 1936

Special Issue Editors

Dr. Liora Mihaela Colobățiu

E-Mail Website
Guest Editor
Department of Medical Devices, Faculty of Pharmacy, Iuliu Hatieganu University of Medicine and Pharmacy, Victor Babes Street No. 8, 400012 Cluj-Napoca, Romania
Interests: antimicrobial resistance mechanisms; antimicrobial resistance epidemiology; Escherichia coli; Salmonella spp.; Clostridium difficile; development and evaluation of new dressing materials
Dr. Marian Mihaiu

E-Mail Website
Guest Editor
Department of Food Safety and Inspection, Faculty of Veterinary Medicine, University of Agricultural Sciences and Veterinary Medicine, Manastur 3-5, 400372 Cluj-Napoca, Romania
Interests: food inspection; food control; antimicrobial resistance mechanisms and epidemiology; molecular methods for antimicrobial resistance detection
Dr. Zorita Diaconeasa

E-Mail Website
Guest Editor
Department of Food Science, Faculty of Food Science and Technology, University of Agricultural Sciences and Veterinary Medicine, Manastur 3-5, 400372 Cluj-Napoca, Romania
Interests: food chemistry; analytic biochemistry; molecular biology
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

In recent years, the safety of our food supply has come under increasing scrutiny due to the emergence of antimicrobial-resistant (AMR) pathogens. These microorganisms pose a significant threat to public health as they diminish the efficacy of existing treatments, leading to prolonged illnesses, increased mortality rates, and higher healthcare costs. The prevalence of AMR in food-borne pathogens, which are transmitted through contaminated food and water, underscores the critical need for a comprehensive approach to mitigate these risks.

Addressing antimicrobial resistance in food-borne pathogens is not just a matter of food safety, but a critical component of the One Health approach, which recognizes the interconnectedness of human, animal, and environmental health in safeguarding our future.

This Special Issue seeks manuscript submissions that further our understanding of antimicrobial resistance, virulence factors, and biofilm formation in food-borne pathogens. We are particularly interested in studies that explore the mechanisms underlying antimicrobial resistance in food-borne bacteria, advances in the detection and characterization of virulence factors and biofilms, and innovative strategies for controlling these threats in food safety practices. Submissions on the development of novel antimicrobial compounds or approaches to disrupt biofilm formation and enhance food safety are also strongly encouraged.

Dr. Liora Mihaela Colobățiu
Dr. Marian Mihaiu
Dr. Zorita Diaconeasa
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Antibiotics is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2900 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • antimicrobial resistance
  • food-borne pathogens
  • food safety
  • virulence factors
  • biofilm formation
  • resistance genes
  • food production
  • public health
  • molecular epidemiology
  • infection control

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Published Papers (2 papers)

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Review

28 pages, 386 KiB  
Review
Screening Methods for Antimicrobial Residues in the Dairy Chain—The Past and the Present
by Pavlína Navrátilová, Lenka Vorlová, Sandra Dluhošová, Klára Bartáková, Oto Hanuš and Eva Samková
Antibiotics 2024, 13(11), 1098; https://doi.org/10.3390/antibiotics13111098 - 19 Nov 2024
Viewed by 729
Abstract
The presence of residues of antimicrobial substances in milk has been an important hygienic and technological parameter of raw milk quality since the 1960s. The presented review focuses on screening methods (microbiological inhibition methods and rapid specific tests) that are used in the [...] Read more.
The presence of residues of antimicrobial substances in milk has been an important hygienic and technological parameter of raw milk quality since the 1960s. The presented review focuses on screening methods (microbiological inhibition methods and rapid specific tests) that are used in the control of antimicrobial residues in milk in the context of their historical development up to the present. We briefly explain the principles of the methods and discuss their pros and cons. The aim was to provide both the historical perspective on this topic and provide useful information on screening methods that are currently routinely used for the detection of residues of antimicrobials at farms, in the dairy industry, and in milk quality control laboratories. Full article
(This article belongs to the Special Issue Emerging Challenges in Food Safety: Addressing Antimicrobial Resistance, Virulence Factors, and Biofilm Formation in Food-Borne Pathogens)
24 pages, 534 KiB  
Review
Dairy Chain Safety in the Context of Antibiotic Residues—Current Status of Confirmatory Liquid Chromatography Methods: A Review
by Sandra Dluhošová, Klára Bartáková, Lenka Vorlová, Pavlína Navrátilová, Oto Hanuš and Eva Samková
Antibiotics 2024, 13(11), 1038; https://doi.org/10.3390/antibiotics13111038 - 3 Nov 2024
Viewed by 944
Abstract
With ever-developing analytical capabilities, the protection of the dairy chain from contamination by residues of veterinary drugs is improving. Legislative requirements are an inherent part of this process. Of antibiotics in dairy farming, representatives of the beta-lactams, tetracyclines, sulfonamides, (fluoro)quinolones, aminoglycosides, or polypeptide [...] Read more.
With ever-developing analytical capabilities, the protection of the dairy chain from contamination by residues of veterinary drugs is improving. Legislative requirements are an inherent part of this process. Of antibiotics in dairy farming, representatives of the beta-lactams, tetracyclines, sulfonamides, (fluoro)quinolones, aminoglycosides, or polypeptide antibiotics are the most widely used. Due to the typically low levels of antibiotic residues in milk, mass spectrometry is the most commonly used detection technique. However, the interference of the sample matrix is one of its main limiting factors, and therefore, it needs to be eliminated. In the first step, the lipid fraction is removed and proteins are precipitated, followed by solid-phase or liquid–liquid extraction. The current trends include the reduction in the consumption of organic solvents (to reduce occupational hazards and burden to the environment) and automation, eliminating the influence of human error and optimizing the workflow. These trends lead to the development of new microextraction and automated techniques as well as the use of new sorbents and/or (green) solvents of natural origin. To capture the latest developments in the field and the relatively recent aforementioned trends, this review focuses on papers investigating antimicrobial residues in milk that were published between 2015 and 2024, providing an overview of emerging techniques applicable to antibiotic residue detection in milk samples. Full article
(This article belongs to the Special Issue Emerging Challenges in Food Safety: Addressing Antimicrobial Resistance, Virulence Factors, and Biofilm Formation in Food-Borne Pathogens)
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