Advanced Antimicrobial Susceptibility Testing and Detection
A special issue of Microorganisms (ISSN 2076-2607). This special issue belongs to the section "Antimicrobial Agents and Resistance".
Deadline for manuscript submissions: closed (31 March 2026) | Viewed by 751
Special Issue Editors
Interests: infection prevention andcontrol; infectious diseases (TB, COVID-19, bacterial and fungal infections); analysis of clinical and microbiological data on microorganisms-related sepsis/infection to guide
Interests: antimicrobial resistance microorganisms
2. School of Laboratory Medicine and Medical Sciences, College of Health Sciences, University of KwaZulu-Natal, Durban, South Africa
Interests: antimicrobial susceptibility patterns; uti in pregnant women; resistance genes; uropathogens; porins
Special Issue Information
Dear Colleagues,
It is our privilege to serve as Guest Editors of this Special Issue titled “Advanced Antimicrobial Susceptibility Testing and Detection”, which will offer valuable insight.
Carbapenem-resistant Gram-negative bacteria (GNB) represent one of the most urgent global health threats, owing to their intrinsic and acquired resistance mechanisms, the limited therapeutic options associated with them, and their high mortality rates in vulnerable patient populations. Among them, carbapenemase-producing Enterobacterales (CPE), Acinetobacter baumannii, and intrinsically carbapenem-resistant organisms such as Stenotrophomonas maltophilia are of particular concern in intensive care units and other high-risk clinical environments.
While phenotypic antimicrobial susceptibility testing remains essential for guiding initial treatment decisions, the growing variety of resistance mechanisms calls for the use of genotypic assays to accurately identify carbapenemase genes and other molecular markers. The integration of phenotypic and genotypic results provides a more comprehensive diagnostic framework, allowing clinicians to distinguish between intrinsic and acquired resistance, monitor emerging resistance patterns, and implement appropriate treatment and infection prevention strategies.
This Special Issue will feature contributions that deepen our understanding of both the laboratory and clinical aspects of carbapenem resistance. By showcasing advancements in detection technologies and their clinical applications, these articles emphasize the need to align diagnostic precision with antimicrobial stewardship to enhance patient outcomes.
Through this collective effort, we aim to strengthen the evidence base needed for effective management of infections caused by CRE, Stenotrophomonas maltophilia, and Acinetobacter spp., and to contribute to global strategies in combating the growing challenge of multidrug-resistant Gram-negative pathogens.
The focal points and target organisms include, but are not limited to, those mentioned above and the following:
- Multidrug-resistant Gram-positive bacteria;
- Other multidrug-resistant Gram-negative bacteria;
- STD/STI-related microorganisms.
Dr. Jeannette Wadula
Dr. Khine Swe Han
Dr. Prathna Bhola
Guest Editors
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 250 words) can be sent to the Editorial Office for assessment.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Microorganisms is an international peer-reviewed open access monthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2700 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
Keywords
- multidrug-resistant
- gram-positive bacteria
- gram-negative bacteria
- pathogens
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