Sarcopenia: Skeletal Muscle Health and Ageing

Dear Colleagues,

Sarcopenia is a skeletal muscle disease identified by low muscle mass and characterised by weakness and impaired physical function. Muscle decline is progressive over the adult life course and may be accelerated in older age or aggravated by periods of disuse due to illness, injury, hospitalisation, sedentary living, malnutrition, and the presence of co-morbidities, eventually leading to sarcopenia. The socio-economic costs of sarcopenia will increase considerably as the global population of older adults rises at a greater rate than the other age groups. This highlights the pressing need to raise awareness of sarcopenia and the possible therapeutic strategies, and to understand the underlying disease processes. For this Topical Collection of “Sarcopenia: Skeletal Muscle Health and Ageing”, we are inviting relevant original research, systematic reviews, and meta-analyses covering the following:

- The incidence of sarcopenia in the general population and amongst specialist populations where disuse or deconditioning are major concerns

- The use of exercise, lifestyle, or pharmaceutical therapies to combat sarcopenia

- Application of new technologies to diagnose and manage sarcopenia

- The risk of adverse outcomes when sarcopenic individuals experience illness, serious injury, or surgery

- The distinction between sarcopenia, wasting, and cachexia

- Interventions that can be applied as pre-habilitation or at the bedside to prevent accelerated muscle wasting and improve recovery outcomes.

Prof. Jamie McPhee
Collection Editor

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