It is often reported in the forecast combination literature that a simple average of candidate forecasts is more robust than sophisticated combining methods. This phenomenon is usually referred to as the “forecast combination puzzle”. Mot...
Considering the influence of the ionosphere, troposphere, and other systematic errors on double-differenced ambiguity resolution (AR), we present an optimal triple-frequency code-phase combination determination method driven by both the model and the...
Peptide receptor radionuclide therapy (PRRT) is a successful targeted radionuclide therapy in neuroendocrine tumors (NETs). However, complete responses remain elusive. Combined treatments anticipate synergistic effects and thus better responses by co...
Forecast combination has been proven to be a very important technique to obtain accurate predictions for various applications in economics, finance, marketing and many other areas. In many applications, forecast errors exhibit heavy-tailed behaviors...
In this paper, the dual combination–combination hybrid synchronization (DCCHS) scheme has been investigated in fractional-order chaotic systems with a distinct dimension applying a scaling matrix. The formulations for the active control have be...
The differential evolution (DE) algorithm is a popular and efficient evolutionary algorithm that can be used for single objective real-parameter optimization. Its performance is greatly affected by its parameters. Generally, parameter control strateg...
Adjuvants are crucial components of vaccines. They significantly improve vaccine efficacy by modulating, enhancing, or extending the immune response and at the same time reducing the amount of antigen needed. In contrast to previously licensed adjuva...
The emergence of pandemic H1N1 influenza viruses in April 2009 and the continuous evolution of highly pathogenic H5N1 influenza viruses underscore the urgency of novel approaches to chemotherapy for human influenza infection. Anti-influenza drugs are...
Neuroblastoma is the most common extracranial solid tumor found in childhood and is responsible for 15% of deaths among children with cancer. Although multimodal therapies focused on surgery, chemotherapy, radiotherapy, and stem cell transplants have...
It is well recognized today that anticancer drugs often are most effective when used in combination. However, the establishment of chemotherapy as key modality in clinical oncology began with sporadic discoveries of chemicals that showed antiprolifer...
Both the statistical machine translation (SMT) model and neural machine translation (NMT) model are the representative models in Uyghur–Chinese machine translation tasks with their own merits. Thus, it will be a promising direction to combine the adv...
This study delves into the intricacies of variable load combination factors (ψ) within structural codes under fundamental design scenarios, with Eurocodes serving as the primary reference. Currently, variable loads are combined by adding one load...
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Background/Objectives: Limited robust data support the use of antibiotic combinations in the treatment of orthopedic infections. However, in certain situations, the combination of antibiotics seems to be beneficial. This review aims to outline the ci...
A new predefined time sliding mode control theme is proposed and applies to the multi-switch combination–combination synchronization (MSCCS) of fractional-order (FO) hyperchaotic systems. Firstly, based on the Lyapunov stability theory, we demo...
In the eukaryotic cells, the ubiquitin–proteasome system (UPS) plays a crucial role in the intracellular protein turnover. It is involved in several cellular functions such as the control of the regular cell cycle progression, the immune survei...
This study concerns the combination of the permanent and the variable loads in the structural design. The Eurocodes are used as a reference. Three new findings are presented: (1) In each physical structure, and in every load pair of the permanent loa...
Under the action of the same wind azimuth, the extreme values of the wind load effect components of building structures are generated in the along-wind, cross-wind, vertical, and torsional directions. In designing the wind-resistant structure, the ex...
Malaria is a vector- and blood-borne infection that is responsible for a large number of deaths around the world. Most of the currently used antimalarial therapeutics suffer from drug resistance. The other limitations associated with the currently us...
In exploratory search, users sometimes combine two or more issued queries into new queries. We present such a kind of search behavior as query combination behavior. We find that the queries after combination usually can better meet users’ infor...
Essential oils (EOs) have been long recognized for their antibacterial, antifungal, antiviral, insecticidal and antioxidant properties. They are widely used in medicine and the food industry for these purposes. The increased interest in alternative n...
Coded distributed computing (CDC) is a powerful approach to reduce the communication overhead in distributed computing frameworks by utilizing coding techniques. In this paper, we focus on the CDC problem in
The advent of novel immunotherapies in the treatment of cancers has dramatically changed the landscape of the oncology field. Recent developments in checkpoint inhibition therapies, tumor-infiltrating lymphocyte therapies, chimeric antigen receptor T...
Current modalities of cancer treatment have limitations related to poor target selectivity, resistance to treatment, and low response rates in patients. Accumulating evidence over the past few decades has demonstrated the capacity of several strains...
Forecast combination methods reduce the information in a vector of forecasts to a single combined forecast by using a set of combination weights. Although there are several methods, a typical strategy is the use of the simple arithmetic mean to obtai...
Background: Combination therapy with antihypertensive agents utilises different mechanisms of action and may be responsible for a more effective decrease in blood pressure. Objective: To review the recently published trials on efficacy and safety of...
We propose probability and density forecast combination methods that are defined using the entropy regularized Wasserstein distance. First, we provide a theoretical characterization of the combined density forecast based on the regularized Wasserstei...
In this paper, we put forward the model of multiple linear-combination security multicast network coding, where the wiretapper desires to obtain some information about a predefined set of multiple linear combinations of the source symbols by eavesdro...
With the rapid development of wireless communications, the occupation of time and frequency resources becomes more crowded. The exploitation of space resources is necessary and the diversity combining techniques have substantial applications. Diversi...
31 March 2022
Multiple illness is an increasingly common phenomenon. Its consequence is the need for polytherapy, which is particularly common among people suffering from arterial hypertension. The development of combined preparations (containing at least two API-...
The exact distribution of the linear combination α X + β Y is derived when X and Y are exponential and gamma random variables distributed independently of each other. A measure of entropy of the linear combination is investigated. We also provide com...
This study introduces a novel forecast combination method for monthly Japanese tourism demand, analyzed at both aggregated and disaggregated levels, including tourist, business, and other travel purposes. The sample period spans from January 1996 to...
Biological drugs have revolutionized the management of severe asthma. However, a variable number of patients remain uncontrolled or only partially controlled even after the appropriate administration of a biologic agent. The combination of two biolog...
With the rapidly spreading resistance of Plasmodium falciparum to available non-artemisinin antimalarial drugs, new and novel pharmaceuticals are needed. ARCO® is a new generation ACT, one of several artemisinin-based combinations developed in China...
To address the common drawbacks of current disinfection robots, which include the potential for secondary environmental pollution, disinfection dead corners, and low efficiency, in this paper, an autonomous mobile combination disinfection system is p...
Schistosomiasis is a major neglected tropical disease. Treatment for schistosomiasis with praziquantel (PZQ), which is effective against the parasite, by itself is not capable to counteract infection-associated disease lesions including hepatic fibro...
In this paper, we develop a modified adaptive combination strategy for the distributed estimation problem over diffusion networks. We still consider the online adaptive combiners estimation problem from the perspective of minimum variance unbiased es...
To avoid the risk of misspecification between homoscedastic and heteroscedastic models, we propose a combination method based on ordinary least-squares (OLS) and generalized least-squares (GLS) model-averaging estimators. To select optimal weights fo...
Glioblastoma is currently an incurable disease despite the development of a wide variety of therapeutic approaches, from surgical methods to immunotherapy. In current clinical practice, treatment typically involves a combination of existing methods,...
Osteoporosis is a multifactorial disease, the pathogenesis of which is caused by a complex interaction of genetic, hormonal, and metabolic factors. The challenges of early diagnosis highlight the need to identify genetic predictors to prevent bone mi...
This paper proposes a new linear combination model to predict the closing prices on multivariate financial data sets. The new approach integrates two delays of deep learning methods called the two-delay combination model. The forecasts are derived fr...
Image denoising is a classic but still important issue in image processing as the denoising effect has a significant impact on subsequent image processing results, such as target recognition and edge detection. In the past few decades, various denois...
Phage therapy is an alternative therapy that is being used as the last resource against infections caused by multidrug-resistant bacteria after the failure of standard treatments. Pseudomonas aeruginosa can cause pneumonia, septicemia, urinary tract,...
Oral cancer is a highly aggressive tumor with invasive properties that can lead to metastasis and high mortality rates. Conventional treatment strategies, such as surgery, chemotherapy, and radiation therapy, alone or in combination, are associated w...
An increasing number of people is affected by fungal biofilm-based infections, which are resistant to the majority of currently-used antifungal drugs. Such infections are often caused by species from the genera Candida, Aspergillus or Cryptococcus. O...
Background/Objectives: Pain is a growing public health concern worldwide, and the use of combinations of drugs can improve their analgesic effects while minimizing their adverse effects. Drugs such as metformin (antidiabetic) and melatonin (sleep reg...
Pancreatic cancer is one of the deadliest causes of cancer-related death in the United States, with a 5-year overall survival rate of 6 to 8%. These statistics suggest that immediate medical attention is needed. Gemcitabine (GEM) is the gold standard...
A passive micromixer was designed by combining two mixing units: the cross-channel split and recombined (CC-SAR) and a mixing cell with baffles (MC-B). The passive micromixer was comprised of eight mixing slots that corresponded to four combination u...
Malignant melanoma is skin cancer with high metastatic potential and resistance to treatment. Significant progress has been made following the introduction of its treatment kinase inhibitors such as binimetinib. Some studies suggested that the combin...
Culinary herbs and spices are known to be good sources of natural antioxidants. Although the antioxidant effects of individual culinary herbs and spices are widely reported, little is known about their effects when used in combination. The current st...
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