Multidrug Combinations

Dear Colleagues,

One possible way to overcome or delay the development of drug resistance is to treat patients with combinations of different drugs, probably because the combination treatment approach works by different molecular mechanisms. For cancer, the other approach is based on the treatment of patients with drugs that block the particular resistance mechanism that tumors have developed, and in a second step, using other drugs to improve intrinsic resistance.

I believe that we need to work on developing a new generation of drug combinations to strike a balance between increased efficacy and decreased toxicity. This Special Issue on Multidrug Combinations, will consider publications on several topics, including:

• Combining cancer drugs
• Precision medicine
• Drug–drug interactions
• Drug repurposing in drug combinations
• Peptide as a drug in biomedicine
• Drug metabolism
• Alteration in the tumor microenvironment
• High-throughput screening
• Keeping cancer drugs inside cells
• Epigenetic alteration and drug resistance/combination

Biomolecules is an open access journal and therefore all manuscripts will be published as soon as they are accepted and will be accessible online free of charge to all readers. The article processing charge is 650 CHF per published manuscript. The deadline for submissions is 15 November 2018.

Prof. Nuno Vale
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 250 words) can be sent to the Editorial Office for assessment.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Biomolecules is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2700 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.