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11,042 Results Found

  • Article
  • Open Access
217 Views
25 Pages

A Systems Engineering Design Framework for University Air Traffic Control Simulators: Integrating Regulatory Requirements, Human Factors, and Infrastructure Design

  • Ioana Catalina Enache,
  • Oana Roxana Chivu,
  • Răzvan Lepădatu,
  • Timur-Vasile Chiș and ,
  • Vitor J. Sá and
  • Berna Haktanirlar Ulutas
  • + 1 author+ 0 author

19 October 2026

Air traffic control (ATC) simulators are essential tools for controller training, operational research and higher education, enabling realistic practice without affecting live air traffic. Although commercial simulation platforms are widely available...

(This article belongs to the Topic Circularity Research and Innovation Towards Sustainable Cities and Built Environment)
  • Article
  • Open Access
1,703 Views
11 Pages

23 February 2025

WiFi (wireless fidelity) signals, renowned for their extensive coverage, absence of electromagnetic pollution, and robust penetration capabilities, are exceptionally well suited for serving as an external radiation source in target detection and envi...

  • Article
  • Open Access
4 Citations
3,613 Views
14 Pages

Effectiveness of Mechanical Design Optimization Using a Human-in-the-Loop Simulator for the Development of a Pediatric Surgical Robot

  • Kazuya Kawamura,
  • Hiroto Seno,
  • Yo Kobayashi,
  • Satoshi Ieiri and ,
  • Makoto Hashizume and
  • Masakatsu G. Fujie
  • + 1 author+ 0 author

2 October 2019

In pediatric surgery, robotic technology is useful. However, it is difficult to apply this technology due to size-related problems. In our study, we proposed a mechanical design method using a human-in-the-loop type simulator, and the moving volume a...

(This article belongs to the Special Issue Next-Generation Surgical Robotics)
  • Article
  • Open Access
20 Citations
4,370 Views
18 Pages

Effects of Simulated Microgravity In Vitro on Human Metaphase II Oocytes: An Electron Microscopy-Based Study

  • Selenia Miglietta,
  • Loredana Cristiano,
  • Maria Salomé B. Espinola,
  • Maria Grazia Masiello and ,
  • Giulietta Micara,
  • Ezio Battaglione,
  • Antonella Linari,
  • Maria Grazia Palmerini,
  • Giuseppe Familiari and
  • Stefania A. Nottola
  • + 8 authors+ 3 authors

9 May 2023

The Gravity Force to which living beings are subjected on Earth rules the functionality of most biological processes in many tissues. It has been reported that a situation of Microgravity (such as that occurring in space) causes negative effects on l...

(This article belongs to the Section Cell Microenvironment)
  • Article
  • Open Access
21 Citations
6,079 Views
18 Pages

The Effect of Human Milk Oligosaccharides and Bifidobacterium longum subspecies infantis Bi-26 on Simulated Infant Gut Microbiome and Metabolites

  • Krista Salli,
  • Johanna Hirvonen,
  • Heli Anglenius,
  • Ashley A. Hibberd and ,
  • Ilmari Ahonen,
  • Markku T. Saarinen,
  • Johanna Maukonen and
  • Arthur C. Ouwehand
  • + 3 authors+ 0 author

Human milk oligosaccharides (HMOs) shape the developing infant gut microbiota. In this study, a semi-continuous colon simulator was used to evaluate the effect of 2 HMOs—2′-fucosyllactose (2′-FL) and 3-fucosyllactose (3-FL)—on...

(This article belongs to the Special Issue Novel Strategies in the Study of the Human Gut Microbiota)
  • Article
  • Open Access
8 Citations
3,907 Views
15 Pages

Molecular Dynamics Simulations Study of the Interactions between Human Dipeptidyl-Peptidase III and Two Substrates

  • Shitao Zhang,
  • Shuai Lv,
  • Xueqi Fu,
  • Lu Han and ,
  • Weiwei Han and
  • Wannan Li
  • + 1 author+ 0 author

27 October 2021

Human dipeptidyl-peptidase III (hDPP III) is capable of specifically cleaving dipeptides from the N-terminal of small peptides with biological activity such as angiotensin II (Ang II, DRVYIHPF), and participates in blood pressure regulation, pain mod...

(This article belongs to the Special Issue Advances in Computational Chemistry for Drug Design, Discovery and Screening)
  • Article
  • Open Access
76 Citations
11,308 Views
17 Pages

Food Matrix Effects of Polyphenol Bioaccessibility from Almond Skin during Simulated Human Digestion

  • Giuseppina Mandalari,
  • Maria Vardakou,
  • Richard Faulks,
  • Carlo Bisignano and ,
  • Maria Martorana,
  • Antonella Smeriglio and
  • Domenico Trombetta
  • + 2 authors+ 0 author

15 September 2016

The goal of the present study was to quantify the rate and extent of polyphenols released in the gastrointestinal tract (GIT) from natural (NS) and blanched (BS) almond skins. A dynamic gastric model of digestion which provides a realistic simulation...

(This article belongs to the Special Issue Polyphenols for Cancer Treatment or Prevention)
  • Proceeding Paper
  • Open Access
1 Citations
3,345 Views
4 Pages

Simulation Model to Evaluate Human Comfort Factors for an Office in a Building

  • Raghavalu Thirumalai Durai Prabhakaran,
  • Simon F. Curling,
  • Morwenna Spear and
  • Graham A. Ormondroyd

According to the literature, both advanced and developing countries are facing several challenges due to the lack of clean energy and emissions of CO2 leading to climate change. Especially in the built environment, energy efficient buildings are high...

(This article belongs to the Proceedings of Sustainable Places 2018)
  • Article
  • Open Access
2 Citations
1,420 Views
21 Pages

1 March 2025

Currently, Industry 4.0 creates new opportunities for analyzing data on production processes and extracting knowledge from them. With the Internet of Things, data is continuously collected from machine sensors to analyze machine health. Thanks to art...

(This article belongs to the Section F: Engineering and Materials)
  • Proceeding Paper
  • Open Access
4 Citations
3,681 Views
10 Pages

Simulation of Low-Frequency Sonophoretic Piezoelectric Transducer Applied over Human Skin

  • Sehreen Moorat,
  • Ahsan Ahmed Ursani,
  • Aftab Memon,
  • Nashrul Fazli Mohd Nasir and
  • Bhawani S. Chowdhry

Sonophoresis is the process that involves the passage of drug molecules through the skin under ultrasonic stimulation. Drugs with a molecular weight greater than 500 daltons require some kind of stimulus to catalyze their penetration into the skin. L...

(This article belongs to the Proceedings of The 2nd International Conference on Emerging Trends in Electronic and Telecommunication Engineering)
  • Review
  • Open Access
10 Citations
7,498 Views
24 Pages

A Review of Human Circulatory System Simulation: Bridging the Gap between Engineering and Medicine

  • Abdulrahman Mahmoud,
  • Abdullah Alsalemi,
  • Faycal Bensaali,
  • Ali Ait Hssain and
  • Ibrahim Hassan

28 September 2021

(1) Background: Simulation-based training (SBT) is the practice of using hands-on training to immerse learners in a risk-free and high-fidelity environment. SBT is used in various fields due to its risk-free benefits from a safety and an economic per...

(This article belongs to the Special Issue Advances in Extracorporeal Membrane Oxygenation)
  • Article
  • Open Access
715 Views
19 Pages

Unravelling the Interaction Mechanism Between Oryzanol and Human Serum Albumin: An Integrated Approach Using Multispectral Analysis and Molecular Simulations

  • Chenge Zhang,
  • Siyi Zhu,
  • Shanshan Duan,
  • Keyu Meng and ,
  • Menglin Guo,
  • Lanlan Wei,
  • Jiayi Shi and
  • Fuqiang Liang
  • + 3 authors+ 0 author

18 April 2026

Gamma-oryzanol (Ory), a major bioactive constituent of rice bran oil, has attracted increasing attention because of its antioxidant and cholesterol-lowering properties. In this study, the interactions between Ory and human serum albumin (HSA) and the...

(This article belongs to the Section Food Analytical Methods)
  • Article
  • Open Access
10 Citations
2,115 Views
30 Pages

Flavonifractor plautii as a Next-Generation Probiotic Enhancing the NGP F/P Index in a Simulated Human Gut Microbiome Ecosystem

  • Md Sarower Hossen Shuvo,
  • Sukyung Kim,
  • Sujin Jo,
  • Md Abdur Rahim and ,
  • Indrajeet Barman,
  • Mohammed Solayman Hossain,
  • Youjin Yoon,
  • Hanieh Tajdozian,
  • Izaz Ahmed and
  • Ho-Yeon Song
  • + 12 authors+ 7 authors

Background/Objectives: Traditionally consumed fermented foods and lactic acid bacteria (LAB)-based products have primarily been investigated for their nutritional and health-promoting benefits as dietary supplements. More recently, research has advan...

(This article belongs to the Section Drug Targeting and Design)
  • Article
  • Open Access
419 Views
23 Pages

From Simulation to Shop Floor: A Human-Centered Digital Twin Methodology for Industry 5.0

  • Francesco Biondani,
  • Luigi Capogrosso,
  • Francesco Tosoni,
  • Nicola Dall’Ora and ,
  • Enrico Fraccaroli and
  • Franco Fummi
  • + 1 author+ 0 author

26 August 2026

Recent advances in Digital Twin technology focus on visualization, operator training, and real-time machine simulation, aligning with the Industry 4.0 paradigm. However, the transition toward Industry 5.0 demands human-centric approaches that integra...

(This article belongs to the Section Human–Computer Interactions)
  • Article
  • Open Access
13 Citations
4,693 Views
17 Pages

A Co-Simulation Model Integrating a Musculoskeletal Human Model with Exoskeleton and Power Tool Model

  • Carla Molz,
  • David Scherb,
  • Christopher Löffelmann,
  • Johannes Sänger and ,
  • Zhejun Yao,
  • Andreas Lindenmann,
  • Sven Matthiesen,
  • Robert Weidner,
  • Sandro Wartzack and
  • Jörg Miehling
  • + 5 authors+ 0 author

19 March 2024

Working at and above head height with a power tool represents a common activity in craft and assembly applications. To assist and protect the user from overload and injuries in these situations, the development and use of application-specific support...

(This article belongs to the Special Issue Novel Approaches and Applications in Ergonomic Design III)
  • Article
  • Open Access
2 Citations
703 Views
23 Pages

30 January 2026

Constructing ecological networks (ENs) is an effective measure to mitigate the conflict between urban development and ecological conservation. However, existing simulating methods lack adequate consideration of human ecological demands and the spatia...

  • Article
  • Open Access
10 Citations
7,621 Views
31 Pages

Novel Human-in-the-Loop (HIL) Simulation Method to Study Synthetic Agents and Standardize Human–Machine Teams (HMT)

  • Praveen Damacharla,
  • Parashar Dhakal,
  • Jyothi Priyanka Bandreddi,
  • Ahmad Y. Javaid and ,
  • Jennie J. Gallimore,
  • Colin Elkin and
  • Vijay K. Devabhaktuni
  • + 2 authors+ 0 author

25 November 2020

This work presents a multi-year study conducted at the University of Toledo, aimed at improving human–machine teaming (HMT) methods and technologies. With the advent of artificial intelligence (AI) in 21st-century machines, collaboration betwee...

(This article belongs to the Collection Advances in Automation and Robotics)
  • Article
  • Open Access
6 Citations
7,225 Views
13 Pages

30 October 2018

Distributed expertise task environments represent a critical, but challenging, area of team performance. As teams work together to perform complex tasks, they share much information and expertise to efficiently and effectively coordinate activities....

  • Article
  • Open Access
17 Citations
4,805 Views
19 Pages

Impact of the Sub-Grid Scale Turbulence Model in Aeroacoustic Simulation of Human Voice

  • Martin Lasota,
  • Petr Šidlof,
  • Manfred Kaltenbacher and
  • Stefan Schoder

23 February 2021

In an aeroacoustic simulation of human voice production, the effect of the sub-grid scale (SGS) model on the acoustic spectrum was investigated. In the first step, incompressible airflow in a 3D model of larynx with vocal folds undergoing prescribed...

(This article belongs to the Special Issue Computational Methods and Engineering Solutions to Voice II)
  • Article
  • Open Access
3 Citations
3,370 Views
18 Pages

13 August 2024

The global healthcare market is expanding, with a particular focus on personalized care for individuals who are unable to leave their homes due to the COVID-19 pandemic. However, the implementation of personalized care is challenging due to the need...

(This article belongs to the Special Issue State-of-the-Art of Computer Vision and Pattern Recognition)
  • Article
  • Open Access
5 Citations
3,043 Views
8 Pages

Simulation and Evaluation of the Radiation Dose Deposited in Human Tissues by Atmospheric Neutrons

  • Ernesto Ortiz,
  • Blanca Mendoza,
  • Carlos Gay,
  • Victor Manuel Mendoza and ,
  • Marni Pazos and
  • Rene Garduño
  • + 1 author+ 0 author

9 September 2021

The evaluation of the radiation dose (RD) deposited by atmospheric neutrons in human tissues is of vital importance due to the potential damages that over exposure to this radiation may cause to human health. The goal of this work was to obtain the R...

(This article belongs to the Special Issue Research on Cosmic Rays and Their Impact on Human Activities)
  • Article
  • Open Access
3 Citations
3,288 Views
20 Pages

12 May 2025

Human–machine interface (HMI) systems are increasingly utilized to develop assistive technologies for individuals with disabilities and older adults. This study proposes two HMI systems using piezoelectric sensors to detect facial muscle activa...

(This article belongs to the Special Issue Wearable Sensors, Robotic Systems and Assistive Devices)
  • Article
  • Open Access
15 Citations
4,070 Views
13 Pages

29 January 2024

Alzheimer’s disease and Type 2 diabetes are two epidemiologically linked diseases which are closely associated with the misfolding and aggregation of amyloid proteins amyloid-β (Aβ) and human islet amyloid polypeptide (hIAPP), respect...

(This article belongs to the Section Molecular Biophysics)
  • Article
  • Open Access
30 Citations
11,261 Views
16 Pages

A Finite-Element Simulation of Galvanic Coupling Intra-Body Communication Based on the Whole Human Body

  • Yong Song,
  • Kai Zhang,
  • Qun Hao,
  • Lanxin Hu and ,
  • Jingwen Wang and
  • Fuzhou Shang
  • + 1 author+ 0 author

9 October 2012

Simulation based on the finite-element (FE) method plays an important role in the investigation of intra-body communication (IBC). In this paper, a finite-element model of the whole body model used for the IBC simulation is proposed and verified, whi...

(This article belongs to the Special Issue Body Sensor Networks for Healthcare and Pervasive Applications)
  • Article
  • Open Access
6 Citations
3,534 Views
16 Pages

Mechanical Behaviour of Human and Porcine Urethra: Experimental Results, Numerical Simulation and Qualitative Analysis

  • António Diogo André,
  • Bruno Areias,
  • Ana Margarida Teixeira,
  • Sérgio Pinto and
  • Pedro Martins

26 October 2022

Low urinary tract dysfunctions and symptoms (LUTS) affect both men and woman, with the incidence increasing with age. Among the LUTS, urinary incontinence (UI) is a common dysfunction, characterised by the involuntary loss of urine. These medical con...

(This article belongs to the Section Applied Biosciences and Bioengineering)
  • Article
  • Open Access
17 Citations
9,997 Views
21 Pages

15 October 2018

Manufacturing and service processes are composed of several elements: Technical, financial, logistics, information and human resources. Staff deployment and staffing is an essential problem in the human resource management domain because the structur...

(This article belongs to the Special Issue Sustainable Human Resource Management)
  • Article
  • Open Access
3 Citations
1,734 Views
13 Pages

6 February 2026

Understanding how different debriefing formats impact learner’s cognitive load is crucial for designing effective post-simulation reflection activities. This paper examines cognitive load after post-simulation debriefings facilitated either by...

(This article belongs to the Special Issue Redefining Education with Immersive Technologies: Transforming Education with AR and VR)
  • Article
  • Open Access
8 Citations
10,635 Views
9 Pages

17 April 2009

Amyloid diseases such as Alzheimer’s and thrombosis are characterized by an aberrant assembly of specific proteins or protein fragments into fibrils and plaques that are deposited in various tissues and organs. The single-domain fragment of a camelid...

(This article belongs to the Section Physical Chemistry, Theoretical and Computational Chemistry)
  • Article
  • Open Access
5 Citations
13 Views

31 December 2020

A novel model of heat and moisture transfer in human-chemical protective clothing-environment is proposed to predict the human physiological regulatory response wearing chemical protective clothing (CPC). The human thermal model is developed by divid...

  • Article
  • Open Access
13 Citations
7,887 Views
22 Pages

As recommended by the international standards, ISO 21542, ease of wayfinding must be ensured by installing signage at all key decision points on walkways such as forks because signage greatly influences the way in which people unfamiliar with an envi...

(This article belongs to the Special Issue 3D Indoor Modelling and Navigation)
  • Article
  • Open Access
5 Citations
2,022 Views
17 Pages

The integration of autonomous vehicles (AVs) into urban transportation systems has significant potential to enhance traffic efficiency and reduce environmental impacts. This study evaluates the impact of different AV penetration scenarios (0%, 10%, 3...

(This article belongs to the Section Smart System Infrastructure and Applications)
  • Review
  • Open Access
138 Citations
18,797 Views
22 Pages

The platform of a microscopic traffic simulation provides an opportunity to study the driving behavior of vehicles on a roadway system. Compared to traditional conventional cars with human drivers, the car-following behaviors of autonomous vehicles (...

(This article belongs to the Special Issue Feature Papers for Smart Cities)
  • Article
  • Open Access
3 Citations
3,070 Views
21 Pages

Education is highly valued in Asian families. However, as family members age, competition for intra-family resources affects children’s actualization in the family, which impacts the family’s future capital. However, most existing studies...

  • Feature Paper
  • Review
  • Open Access
20 Citations
9,089 Views
15 Pages

In Vitro Simulation of Human Colonic Fermentation: A Practical Approach towards Models’ Design and Analytical Tools

  • Elena Veintimilla-Gozalbo,
  • Andrea Asensio-Grau,
  • Joaquim Calvo-Lerma,
  • Ana Heredia and
  • Ana Andrés

2 September 2021

The human colonic microbiota plays an important role in the food digestion process and has a key role in maintaining health status. This community of microbes is inter-individually different due to several factors that modulate its composition. Among...

(This article belongs to the Special Issue Applied Microbiology in Food Technology)
  • Review
  • Open Access
25 Citations
6,208 Views
23 Pages

Business Simulation Games Analysis Supported by Human-Computer Interfaces: A Systematic Review

  • Cleiton Pons Ferreira,
  • Carina Soledad González-González and
  • Diana Francisca Adamatti

14 July 2021

This article performs a Systematic Review of studies to answer the question: What are the researches related to the learning process with (Serious) Business Games using data collection techniques with Electroencephalogram or Eye tracking signals? The...

(This article belongs to the Collection Human-Computer Interaction in Pervasive Computing Environments)
  • Article
  • Open Access
579 Views
20 Pages

10 July 2026

This study presents the development and application of a human-centered assessment protocol for in-vehicle Human–Machine Interfaces (HMIs), suitable for real-vehicle evaluation and designed to support future implementation in simulated environm...

(This article belongs to the Special Issue Human-Centred Design in Ergonomics)
  • Article
  • Open Access
15 Citations
4,244 Views
15 Pages

13 November 2023

Currently, many virtual simulation design studies of compression pants do not consider pressure distribution and human body characteristics. Therefore, this study aimed to optimize the simulation design accuracy of compression pants by investigating...

(This article belongs to the Special Issue Advances in Manufacturing Ergonomics)
  • Article
  • Open Access
7 Citations
6,005 Views
16 Pages

9 March 2020

The comfort level of the human occupant inside a dynamic vehicle is dependent on the level of vibration generated inside the different segments of the human body. Some technologies have been developed to provide the final level of vibration inside an...

(This article belongs to the Section Mechanical Engineering)
  • Article
  • Open Access
25 Citations
7,571 Views
38 Pages

9 October 2019

Modelling and simulation of social interaction and networks are of high interest in multiple disciplines and fields of application ranging from fundamental social sciences to smart city management. Future smart city infrastructures and management are...

(This article belongs to the Special Issue Selected Papers from the 5th International Electronic Conference on Sensors and Applications)
  • Article
  • Open Access
2,045 Views
23 Pages

15 May 2025

The simulation of human soft tissue deformation is a key issue in the research of surgical simulators. The most mathematically accurate model for soft tissue behavior is the finite element model (FEM), being the most widely adopted numerical approach...

(This article belongs to the Special Issue Simulation and Modelling in Natural Sciences, Biomedicine and Engineering III)
  • Article
  • Open Access
44 Citations
6,504 Views
17 Pages

22 February 2020

Maritime pilotage is an important guarantee for the safety of water traffic in port. The pilot is affected by the complex port environment, the differences of crew and equipment of different ships, the physical and psychological pressure of the pilot...

  • Article
  • Open Access
16 Citations
3,914 Views
18 Pages

12 March 2023

Various diffractive, refractive and holographic optical elements, such as diffraction gratings; microlens raster; phase plates; multi-order diffractive optical elements; adaptive mirrors; diffractive and refractive axicons; holographic multiplexes an...

  • Abstract
  • Open Access
873 Views
2 Pages

Introduction: Upper-limb loss results in significant functional impairment and a reduced quality of life. A human–machine interface (HMI) using surface electromyography (sEMG) establishes a link between the user and a hand prosthesis to recogni...

(This article belongs to the Proceedings of The 3rd International Electronic Conference on Processes—Green and Sustainable Process Engineering and Process Systems Engineering)
  • Article
  • Open Access
4 Citations
2,703 Views
21 Pages

23 October 2024

Most exoskeletons designed to assist users in load-bearing tasks face a mechanical dilemma in their conception. Designers may find a compromise between stiff active actuators-based architectures which are powerful but bulky and compliant actuator-bas...

(This article belongs to the Section Systems & Control Engineering)
  • Article
  • Open Access
17 Citations
5,966 Views
16 Pages

29 September 2016

Modern manufacturing systems should satisfy emerging needs related to sustainable development. The design of sustainable manufacturing systems can be valuably supported by simulation, traditionally employed mainly for time and cost reduction. In this...

(This article belongs to the Special Issue Energy Saving Design for Manufacturing Process, Product, and System)
  • Article
  • Open Access
13 Citations
3,356 Views
33 Pages

Microwave Technique for Linear Skull Fracture Detection—Simulation and Experimental Study Using Realistic Human Head Models

  • Mariella Särestöniemi,
  • Daljeet Singh,
  • Mikael von und zu Fraunberg and
  • Teemu Myllylä

6 September 2024

Microwave (MW) sensing is regarded as a promising technique for various medical monitoring and diagnostic applications due to its numerous advantages and the potential to be developed into a portable device for use outside hospital settings. The dete...

(This article belongs to the Section Biosensors and Healthcare)
  • Communication
  • Open Access
1,486 Views
15 Pages

A Simulation-Based Computational Study on the Dielectric Response of Human Hand Tissues to Radiofrequency Radiation from Mobile Devices

  • Agaku Raymond Msughter,
  • Jonathan Terseer Ikyumbur,
  • Matthew Inalegwu Amanyi,
  • Eghwubare Akpoguma and ,
  • Ember Favour Waghbo and
  • Patience Uneojo Amaje
  • + 1 author+ 0 author

13 March 2026

This study presents a computational, simulation-based investigation of the dielectric response of human hand tissues, skin, fat, muscle, and bone to radiofrequency (RF) electromagnetic fields emitted by mobile devices. The widespread adoption of hand...

  • Article
  • Open Access
3 Citations
2,299 Views
17 Pages

13 September 2025

Background/Objectives: The probiotic Lacticaseibacillus paracasei DG (LpDG) has shown promising results for various gastrointestinal diseases. This study evaluated the survival, metabolic activity, and impact on colonic microbiota of LpDG in an in vi...

(This article belongs to the Section Prebiotics, Probiotics and Postbiotics)
  • Article
  • Open Access
4 Citations
3,990 Views
26 Pages

9 May 2022

As one of the key issues in aviation safety, loss-of-control in the form of adverse aircraft-pilot couplings is attracting attention increasingly. Dynamic-pitch-control envelope shows to be a promising means to evaluate the loss-of-control related to...

(This article belongs to the Special Issue Autonomous Flight of Drone: Control, Trajectory Optimization and Mission Planning)
  • Article
  • Open Access
767 Views
23 Pages

12 August 2026

Misalignment between the rotation axis of a lower-limb exoskeleton knee joint and the human knee joint in the sagittal plane introduces additional human-exoskeleton interaction forces, affecting gait and assistance efficiency. This study proposes an...

(This article belongs to the Special Issue Advances in Biomedical Sensing Technologies for Assistive Robotics)

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