Cell Microenvironment
A section of Cells (ISSN 2073-4409).
Section Information
The “Cell Microenvironment” section of Cells aims to publish experimental findings and reviews that provide novel insights and/or conceptual advances to understand bidirectional interactions between diverse cell types and their microenvironment, which includes other cells, interstitial fluid, and the extracellular matrix (ECM) with associated signaling molecules. The focus is on the formation and remodeling of cell microenvironment under physiological and pathophysiological conditions, and its role in governing cell and tissue architecture and function through signaling pathways mediated by cell adhesion molecules, mechanosensitive channels, and receptors to ECM, growth factors, cytokines and neurotransmitters. Relevant research topics in this interdisciplinary field include, but not limited to, the ECM remodeling, mechanotransduction, stem-cell niche, tumor microenvironment, perineuronal nets and synaptic microenvironment, reconstitution and repair of cell microenvironments by injectable ECM scaffolds, gene therapy and pharmacological targeting, experimental modeling of microenvironment using micropatterning and microfluidics, and systems biology of cell microenvironment.
Editorial Board
Topical Advisory Panel
Special Issues
Following special issues within this section are currently open for submissions:
- New Insight into Tumor–Tumor Microenvironment Crosstalk (Deadline: 31 May 2025)
- Cancer-Associated Fibroblasts: Challenges and Directions (Deadline: 31 July 2025)
- Cell–Cell Interactome-Based Therapies for Osteosarcoma (Deadline: 31 July 2025)
- Role of Extracellular Matrix in Cancer and Disease (Deadline: 31 July 2025)
- Targeting Tumor Microenvironments for Enhanced Cancer Immunotherapy (Deadline: 20 August 2025)
- Ovarian Microenvironment and Oocyte Quality: Mechanisms, Aging, and Therapeutic Strategies (Deadline: 25 September 2025)
- Organellar Ca2+ Transport in Plant versus Animal Cells: Can We Learn from Each Other? (Deadline: 30 September 2025)
- The Interplay Between Tumor Metabolism, Microenvironment and Cell Survival (Deadline: 30 September 2025)
- How Can We Optimise Cancer Therapy? Tumour Microenvironment and Immune Evasion Strategies (Deadline: 31 October 2025)
- Harnessing the Tumor Microenvironment and Signaling Pathways for Precision Cancer Therapy (Deadline: 30 November 2025)
- New Targets and Therapeutic Approaches Based on Molecular Mechanisms in Tumorigenesis and Cancer Metastasis (Deadline: 10 December 2025)
- The Role of the Extracellular Vesicles in Kidney Disease (Deadline: 15 December 2025)
- How Does Gene Regulation Affect Cancer Development? (Deadline: 31 December 2025)
- Emerging Targets and Therapeutic Potential Drugs in Tumor Progression and Therapeutic Resistance (Deadline: 31 January 2026)
- Phosphodiesterases (PDEs): Therapeutic Targets in Human Health and Disease (Deadline: 20 February 2026)
- New Concepts Relating Mesenchymal Tumors Based on Genetics and Epigenetics (Deadline: 20 March 2026)
Topical Collections
Following topical collections within this section are currently open for submissions:
