Integrating indium phosphide (InP) material on a gallium arsenide (GaAs) substrate to form an InP/GaAs virtual substrate has been an attractive research subject over the past decade. However, the epitaxial growth of InP on GaAs is challenging due to...
This paper presents an alternative approach to formulating a rational bar-elastic substrate model with inclusion of small-scale and surface-energy effects. The thermodynamics-based strain gradient model is utilized to account for the small-scale effe...
The realization of high-performance Si-based III-V quantum-dot (QD) lasers has long attracted extensive interest in optoelectronic circuits. This manuscript presents InAs/GaAs QD lasers integrated on an advanced GaAs virtual substrate. The GaAs layer...
A lattice matched triple junction solar cell (TJSC) structure with a GaAs0.58 P0.42 top cell and bandgap tunable GaNxAs1-x-zPz middle and bottom cells on virtual SiGe substrate is proposed in this study. SiGe/Si substrate is preferred as it is a low-...
Direct band electroluminescence (EL) from tensile-strained Si0.13Ge0.87/Ge multiple quantum wells (MQWs) on a Ge virtual substrate (VS) at room temperature is reported herein. Due to the competitive result of quantum confinement Stark effect and band...
The serine/threonine kinase, GSK-3, is a promising drug discovery target for treating multiple pathological disorders. Most GSK-3 inhibitors that were developed function as ATP competitive inhibitors, with typical limitations in specificity, safety a...
In this manuscript, a novel dual-step selective epitaxy growth (SEG) of Ge was proposed to significantly decrease the defect density and to create fully strained relaxed Ge on a Si substrate. With the single-step SEG of Ge, the threading defect densi...
ATP-binding cassette (ABC) transporters, particularly those of subfamily B, are involved in cell detoxification, multidrug resistance, drug treatment pharmacodynamics, and also ecological adaptation. In this regard, ABCB transporters may play a decis...
For embedding virtual networks into a large scale substrate network, a massive amount of time is needed to search the resource space even if the scale of the virtual network is small. The complexity of searching the candidate resource will be reduced...
Wireless network virtualization is widely used to solve the ossification problem of networks, such as 5G and the Internet of Things. The most crucial method of wireless network virtualization is virtual network embedding, which allows virtual network...
Network virtualization (NV) is considered a promising technology that may solve the problem of Internet rigidity. The resource competition of multiple virtual networks for shared substrate network resources is a challenging problem in NV called virtu...
Three types of GaAsP metamorphic buffer layers, including linearly graded, step graded, and metamorphic superlattices, were compared for the purposes of virtual substrates for red laser diode heterostructures. Laser diodes were fabricated on GaAs sub...
With the emergence of cloud services based on data centers, demands for bandwidth-intensive applications have increased dramatically, and application services have transferred to a more diversified direction. Management as well as capacity of the bac...
We demonstrate, for the first time, GaAs thin film solar cells epitaxially grown on a Si substrate using a metal wafer bonding and epitaxial lift-off process. A relatively thin 2.1 μm GaAs buffer layer was first grown on Si as a virtual substrate,...
In this study, we describe the input data and processing steps to find antiviral lead compounds by a virtual screen. Two-dimensional and three-dimensional filters were designed based on the X-ray crystallographic structures of viral neuraminidase co-...
Network virtualization can offer more flexibility and better manageability for next generation Internet. With the increasing deployments of virtual networks in military and commercial networks, a major challenge is to ensure virtual network survivabi...
A service function chain (SFC) is an ordered virtual network function (VNF) chain for processing traffic flows to deliver end-to-end network services in a virtual networking environment. A challenging problem for an SFC in this context is to determin...
Network slicing is a vital component of the 5G system to support diverse network scenarios, creating virtual networks (slices) by mapping virtual network requests to real networks. The mapping is an arduous computing process, mathematically studied a...
Targeting enzymes that play a role in the biosynthesis of the bacterial cell wall has long been a strategy for antibacterial discovery. In particular, the cell wall of Mycobacterium tuberculosis (Mtb) is a complex of three layers, one of which is Pep...
Background/Objectives: Cirrhosis significantly alters physiological function and drug metabolism, particularly for medications primarily metabolized by CYP2C19 and CYP3A4. This study aims to establish a physiologically based pharmacokinetic (PBPK) mo...
Hepatic carboxylesterase 1 (CES1) metabolizes numerous prodrugs into active ingredients or direct-acting drugs into inactive metabolites. We aimed to develop a semi-physiologically based pharmacokinetic (semi-PBPK) model to simultaneously predict the...
With the widespread application of wireless sensor networks (WSNs), WSN virtualization technology has received extensive attention. A key challenge in WSN virtualization is the survivable virtual network embedding (SVNE) problem which efficiently map...
Wireless Sensor Networks (WSNs) are gaining tremendous importance thanks to their broad range of commercial applications such as in smart home automation, health-care and industrial automation. In these applications multi-vendor and heterogeneous sen...
Liquid layering, which is a general phenomenon adjacent to the solid substrates, is less understood for its role in heterogeneous nucleation. In this work, the structural features and dynamics of the liquid Al layers induced by the (0001) sapphire an...
Quercetin is a flavonoid largely employed as a phytochemical remedy and a food or dietary supplement. We present here a novel biocatalytic methodology for the preparation of quercetin from plant-derived rutin, with both substrate and product being in...
This paper presents a study of the quartz fibrous filters used as a substrate for capturing the particulate matter (PM) present in the air. Although these substrates are widely used in environmental applications, their microstructure has been barely...
Fluoropolymers such as PFA are used as coatings for the protection of metal substrates due to their high chemical inertia and non-stick properties. These are “wear and tear” coatings and they degrade, at which point they should be removed...
Many specialty crop growers are transitioning high-value crops from in-ground production to soilless culture due to the diminishing availability of fumigants, increasing pest pressure, extreme weather, and the need for flexible production practices....
Aluminum coatings, which are applied by physical vapor deposition (PVD), have to be virtually defect-free in barrier applications for the packaging industry. When aluminum is applied to paper, hygroexpansion and substrate roughness can impair the alu...
Consolidated bioprocessing (CBP) is difficult to monitor because enzyme production, lignocellulose degradation, sugar release, and fermentation occur simultaneously under sparse measurement, feedstock variability, and plant–model mismatch condi...
Lignin, the most abundant aromatic biopolymer, represents a key renewable feedstock for sustainable biorefineries, yet its structural complexity poses a formidable challenge for enzymatic degradation. While ligninolytic enzymes such as laccases (LACs...
Future 6G networks require higher performance and wider service coverage. Multi-domain Service Function Chain (SFC) deployment enables service provisioning across multiple network domains to meet these demands. However, when collaboration occurs amon...
Benzoylformate decarboxylase (BFDC) and pyruvate decarboxylase (PDC) are thiamin diphosphate-dependent enzymes that share some structural and mechanistic similarities. Both enzymes catalyze the nonoxidative decarboxylation of 2-keto acids, yet differ...
Dairy products play a significant role in the human diet, but they are often associated with high freshwater resource depletion. In Italy, the dairy sector represents more than 12% of the total turnover of the agri-food sector. Trentino Alto Adige is...
With the development of virtual reality/augmented reality (VR/AR) display devices, the conventional fine metal mask is limited by the wet etch process, which no longer meets the demand for high pixels per inch (PPI) displays. We deposited a layer of...
Diffractive optical elements (DOEs) are specialized optical components that manipulate light through diffraction for various applications, including holography, spectroscopy, augmented reality (AR) and virtual reality (VR), and light detection and ra...
This paper analyzes how the real part of the dielectric constant affects the emittance or temperature in some materials. A two-layer configuration was implemented on a glass substrate, with theory and experiment, on a sunny day in Mexico. Furthermore...
Bacteria resistance to antibiotics is a concerning global health problem; in this context, methicillin-resistant Staphylococcus aureus (MRSA) is considered as a high priority by the World Health Organization. Furthermore, patients with a positive res...
Network virtualization (NV) technology is the cornerstone of modern network architectures, offering significant advantages in resource utilization, flexibility, security, and streamlined management. By enabling the deployment of multiple virtual netw...
The turbulent flow through a plane channel bounded by a single permeable wall is considered; this is a problem of interest since a carefully chosen distribution of grains and voids in the porous medium can result in skin friction reduction for the fl...
SUMOylation is a reversible post–translational modification (PTM) involving covalent attachment of small ubiquitin-related modifier (SUMO) proteins to substrate proteins. Dysregulation of SUMOylation and deSUMOylation results in cellular malfun...
A three-phase GaN-based motor inverter IC with three integrated phase current mirror sensors (sense-FETs or sense-HEMTs, 1200:1 ratio), a temperature sensor, and an amplifier is presented and experimentally operated. The three low-side currents are r...
The endogenous protease furin is a key protein in many different diseases, such as cancer and infections. For this reason, a wide range of studies has focused on targeting furin from a therapeutic point of view. Our main objective consisted of identi...
Accurately capturing human movements is a crucial element of health status monitoring and a necessary precondition for realizing future virtual reality/augmented reality applications. Flexible motion sensors with exceptional sensitivity are capable o...
Thrombin, a key enzyme of the serine protease superfamily, plays an integral role in the blood coagulation cascade and thrombotic diseases. In view of this, it is worthwhile to establish a method to screen thrombin inhibitors (such as natural flavono...
Wearable data gloves often suffer from electromagnetic interference, insufficient substrate stability, and limited capability for multi-degree-of-freedom motion measurement. To address these limitations, a flexible glove incorporating a hybrid POF-FB...
Homoserine dehydrogenase (HSD) from Mycobacterium leprae TN is an antifungal target for antifungal properties including efficacy against the human pathogen. The 3D structure of HSD has been firmly established by homology modeling methods. Using the t...
NAD(P)H:quinone acceptor oxidoreductase-1 (NQO1) is a ubiquitous flavin adenine dinucleotide-dependent flavoprotein that promotes obligatory two-electron reductions of quinones, quinonimines, nitroaromatics, and azo dyes. NQO1 is a multifunctional an...
Gallium phosphide (GaP) is an ideal candidate to implement a III-V nucleation layer on a silicon substrate. The optimization of this nucleation has been pursued for decades, since it can form a virtual substrate to grow monolithically III-V devices....
The synthesis of enantiomeric forms of D-amino acids can be achieved by a two-step “hydantoinase process” based on the sequential catalysis of substrates by specific enzymes, D-carbamoylase and D-hydantoinase. Here, we describe the struct...
of 5