Congenital tufting enteropathy (CTE) is an autosomal recessive disease of infancy that causes severe intestinal failure with electrolyte imbalances and impaired growth. CTE is typically diagnosed by its characteristic histological features, including...
Tufting enteropathy (TE) is caused by recessive EPCAM mutations, and is characterized by intractable diarrhea of congenital onset and disorganization of enterocytes. TE generally requires parenteral nutrition (PN) during childhood or intestinal bowel...
Background and Clinical Significance: Congenital tufting enteropathy (CTE), or autosomal recessive congenital diarrhea type 5 (DIAR5), is a rare intestinal epithelial disorder characterized by severe neonatal-onset watery diarrhea, failure to thrive,...
The influences of reinforcement by tufting on the interlaminar shear performance of laminated preforms and composites are studied in the present paper. A modified T steel shearing test was established and used to achieve a pure Mode II loading (slidi...
Congenital tufting enteropathy (CTE) is a rare chronic diarrheal disease of infancy caused by mutations in epithelial cell adhesion molecule (EpCAM). Previously, a murine CTE model showed mis-localization of EpCAM away from the basolateral cell surfa...
The aim of study is to determine which environmental factors could influence the biological traits of Z. caespitosa, a unique tuft-forming seagrass. This study examined the dynamics of tufts and the growth of Z. caespitosa, along with the environment...
Background/Objectives: Acinar-to-ductal metaplasia (ADM) refers to the dedifferentiation or transdifferentiation of pancreatic acinar cells. Recently, ADM has received considerable attention as a potential precursor of pancreatic tumours. Previous st...
This study presents a novel sandwich structure that replaces the polypropylene (PP) foam core with a carbon fiber non-woven material in the tufting process and the liquid resin infusion (LRI) process. An experimental investigation was conducted into...
The luminescent mini-tufts method is widely used for flow visualization for quantitative field analysis. A set of numerical methods for digitalization of 3D surfaces surrounding flows with luminescent mini-tufts has been developed in this study. The...
Shape memory alloy (SMA) tufted composites have shown a significant improvement of the mechanical strength, fracture toughness, and delamination resistance of structural joints. This paper investigated the self-sensing functionality of SMA tufted car...
Background/Objective: Eosinophilic chronic rhinosinusitis (ECRS) is a subtype of chronic rhinosinusitis with nasal polyps that is characterized by abundant eosinophilic infiltration within nasal polyps. Tuft cells are epithelial chemosensory cells th...
Shock buffet is one of the critical issues affecting the aerodynamic performance, flight quality, and flight safety of large aircraft. To overcome the limitations of traditional experimental measurement methods, such as insufficient capability in cap...
Tuft cells are more than guardian chemosensory elements of the digestive tract. They produce a variety of immunological effector molecules in response to stimulation; moreover, they are essential for defense against protozoa and nematodes. Beyond the...
Acinar-to-ductal metaplasia (ADM)—a process involving the dedifferentiation or transdifferentiation of pancreatic acinar cells—is recognized as an initial event in pancreatic tumorigenesis. Studies in mouse models have revealed that tuft...
22 February 2022
Pelvic radiotherapy is associated with chronic intestinal dysfunction. Dietary approaches, such as fiber enrichment during and after pelvic radiotherapy, have been suggested to prevent or reduce dysfunctions. In the present paper, we aimed to investi...
In the intestine, the innate immune system excludes harmful substances and invading microorganisms. Tuft cells are taste-like chemosensory cells found in the intestinal epithelium involved in the activation of group 2 innate lymphoid cells (ILC2). Al...
Clarifying the distribution pattern and overlapping relationship of sympatric relative species in the spatio-temporal niche is of great significance to the basic theory of community ecology and integrated management of multi-species habitats in the s...
Molar incisor hypomineralization (MIH) is a developmental defect that affects the enamel tissue of permanent teeth. Clinicians may observe a range of opacities in the affected teeth, varying from white to creamy, yellow, and brown. Of particular inte...
Dietary fibers regulate intestinal barrier function; however, the precise mechanisms remain unclear. This study investigated the effects of psyllium fibers on antimicrobial protein expression, focusing on the type II immunity and tuft cell-group 2 in...
The tufted deer (Elaphodus cephalophus), a Near-Threatened (NT) species endemic to China and Myanmar, requires robust genetic data for effective conservation. However, the genetic landscape of key populations, such as those in Chongqing, remains poor...
In this paper, we addressed the flow patterns over a light boxplane scale model to explain the previously discovered disagreement between its predicted and experimental aerodynamic characteristics. By tuft flow and CFD visualization, we explored the...
(1) Background: Knockout (KO) of heterogeneous nuclear ribonucleoprotein I (Hnrnp I) in mouse intestinal epithelial cells (IECs) induced a severe inflammatory response in the colon, followed by hyperproliferation. This study aimed to investigate the...
Tuft cells are a rare type of epithelial cell that are essential to regulate innate and adaptive immune responses. Mucosal immunity is also composed primarily of IgA produced by B cells that is secreted onto mucosal surfaces as secretory IgA via the...
Continuous and rapid renewal of the intestinal epithelium depends on intestinal stem cells (ISCs). A large repertoire of transcription factors mediates the correct maintenance and differentiation of ISCs along either absorptive or secretory lineages....
Tuft cells (TCs) are rare chemosensory epithelial cells that regulate mucosal homeostasis in multiple organs, but their role in salivary gland (SG) biology remains poorly defined. This study aimed to define TC structure in mice submandibular glands (...
Microtubule-associated doublecortin-like kinase 1 (DCLK1) is an accepted marker of tuft cells (TCs) and several kinds of cancer stem cells (CSCs), and emerging evidence suggests that DCLK1-positive TCs participate in the initiation and formation of i...
Chenille tufted carpets typically use wet dyeing, which consumes large amounts of water, chemicals, and energy and limits pattern control. This study combines dope-dyed filaments with spatial (juxtaposed) color mixing to eliminate post-dyeing and exp...
The powered toothbrush has become a modern dental tool that is available in the supermarket. Indeed, the design of the powered toothbrush, e.g., mechanical and electrical, would affect not only the efficacy but also the safety of the products. This n...
TUFT cells have been described as strong modulators of inflammatory cells in several tissues including pancreas. TUFT cells, also known as DCLK1+ cells, are dependent of the transcriptional factor POU2F3. Several works report DCLK1+ cells in early st...
Our study aimed to quantify the pollen trapped by the seeds and relate it with the airborne pollen concentrations. Individual Populus spp. tuft-like seeds were sampled while suspended twice a day in 2017 and 2018 during the seed dispersal season. The...
Background: The histogenesis of thymic epithelial tumors (TETs) has been a subject of debate. Recent technological advancements have revealed that thymic carcinomas often exhibit a phenotype akin to tuft cells, which is a subset of medullary TECs. He...
Enteric tuft cells are chemosensory epithelial cells gaining attention in the field of host-parasite interactions. Expressing a repertoire of chemosensing receptors and mediators, these cells have the potential to detect lumen-dwelling helminth and p...
Dynamic regulation of intestinal epithelial cell (IEC) proliferation and differentiation is crucial for maintaining mucosa homeostasis and the response to helminth infection. O-GlcNAc transferase (OGT), an enzyme catalyzing the transfer of GlcNAc fro...
Ducks (Anatinae) play a crucial role in wetland ecosystems, contributing to seed dispersal and nutrient cycling. This study investigates the skeletal adaptations of three duck species: the Mallard (Anas platyrhynchos), Tufted Duck (Aythya fuligula),...
TROP1 (EpCAM) and TROP2 are homologous cell surface proteins that are widely expressed, and often co-expressed, in developing and adult epithelia. Various functions have been ascribed to EpCAM and TROP2, but responsible mechanisms are incompletely ch...
The aim of this study is to clarify the deflection, splaying, and abrasion of single tufts of polybutylene terephthalate (PBT) toothbrushes after use. A single-center randomized controlled trial is performed. The changes in deflection, bristle splayi...
Taste receptors are responsible for detecting their ligands not only in taste receptor cells (TRCs) but also in non-gustatory organs. For several decades, many research groups have accumulated evidence for such “ectopic” expression of tas...
The goal of this review is to expand our understanding of how the cellular organization of the normal colonic crypt is maintained and elucidate how this intricate architecture is disrupted during tumorigenesis. Additionally, it will focus on implicat...
In the tumor microenvironment, various stromal and immune cells accumulate and interact with cancer cells to contribute to tumor progression. Among stromal players, nerves have recently been recognized as key regulators of tumor growth. More neurotra...
In addition to the small intestine’s well-known function of nutrient absorption, the small intestine also plays a major role in nutrient sensing. Similar to taste sensors seen on the tongue, GPCR-coupled nutrient sensors are expressed throughout the...
Tuft cells have recently emerged as the focus of intense interest following the discovery of their chemosensory role in the intestinal tract, and their ability to activate Type 2 immune responses to helminth parasites. Moreover, they populate a wide...
This study aimed to explore the directional stability issues of a previously studied light box-wing aircraft model with a pusher propeller engine in the fuselage aft section. Earlier configurations have included the use of fuselage together with a li...
Knowledge of the mechanisms of species coexistence is crucial for biodiversity conservation. The tufted deer (Elaphodus cephalophus), alpine musk deer (Moschus chrysogaster), and Chinese serow (Capricornis milneedwardsii) are all found in alpine ecos...
Knowledge of the pattern of exploitation of trees can help us understand the relationship between marmosets and plants, especially in declining forests, such as those in the Brazilian Cerrado. Black-tufted marmosets (Callithrix penicillata) regularly...
Centrifugal projections in the olfactory system are critical to both olfactory processing and behavior. The olfactory bulb (OB), the first relay station in odor processing, receives a substantial number of centrifugal inputs from the central brain re...
The transition from adolescence to adulthood is a unique period during which lifelong dietary habits are shaped. Dietary patterns (DPs) among young adults attending college have not been adequately described, and associations between DPs and indicato...
The use of composites in industry is increasing due to their ability to replace traditional materials. Carbon fiber-reinforced polymers offer a favorable strength-to-weight ratio, making them advantageous in numerous applications. Delamination is a c...
The production of pancreatic β cells is the most challenging step for curing diabetes using next-generation treatments. Adult pancreatic endocrine cells are thought to be maintained by the self-duplication of differentiated cells, and pancreatic endo...
Human industry and land use has led to the anthropogenic release of manganese (Mn) into the air and soil near manufacturing centers. Overexposure to Mn can cause considerable health problems in birds. We studied whether the concentration of Mn in bir...
Ducks exhibit substantial ecological and dietary diversity, which drives morphological and functional adaptations in their digestive systems. This study analyzed the small intestine and cecum of three wild duck species: Mallard (Anas platyrhynchos),...
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