The clinical use of genomic analysis has expanded rapidly resulting in an increased availability and utility of genomic information in clinical care. We have developed an infrastructure utilizing informatics tools and clinical processes to facilitate...
This study addresses a critical policy paradox in transport infrastructure planning: the necessity for substantial decarbonization investments amid declining freight demand forecasts in less developed territories. Despite reduced demand, such investm...
The failures of interdependent critical infrastructure systems (CISs) caused by disasters could result in significant impacts on the economy and society of cities. Although existing studies have proposed several socioeconomic impact indicators of CIS...
Expressway networks represent evolving complex systems whose topological properties significantly impact regional development. This paper presents a decision support framework for addressing the expressway infrastructure sequencing problem using comp...
The adaptation tipping point and adaptation pathway approach developed to make decisions under deep uncertainty do not shed light on which among the multiple available pathways should be chosen as the preferred pathway. This creates the need to exten...
This paper examines cultural institutions as architectural infrastructures that extend beyond physical boundaries to generate events, shape collective spatial experience, and contribute to the production of urban memory. Instead of interpreting the c...
Next-generation sequencing (NGS) may enable more focused and highly personalized cancer treatment, with the National Comprehensive Cancer Network and European Society for Medical Oncology guidelines now recommending NGS for daily clinical practice fo...
Background/Objectives: Value frameworks are useful tools to explicitly define the dimensions and criteria important for decision-making, but no existing frameworks capture the broad value domains of population genomic programs. Using a mixed methods...
The role of schools as a source of infection and driver in the coronavirus-pandemic has been controversial and is still not completely clarified. To prevent harm and disadvantages for children and adolescents, but also adults, detailed data on school...
Here, we report on the increasing frequency of the SARS-CoV-2 lineage A.27 in Germany during the first months of 2021. Genomic surveillance identified 710 A.27 genomes in Germany as of 2 May 2021, with a vast majority identified in laboratories from...
Indoor positioning technologies are of great use in GPS-denied areas. They can be partitioned into two types of systems—infrastructure-free based and infrastructure-dependent based. WiFi based indoor positioning system is somewhere between the...
The High-performance Integrated Virtual Environment (HIVE) is a high-throughput cloud-based infrastructure developed for the storage and analysis of genomic and associated biological data. HIVE consists of a web-accessible interface for authorized us...
The Cushing Hub in Oklahoma, one of the largest oil storage facilities in the world, is federally designated as critical national infrastructure. In 2014, the formerly aseismic city of Cushing experienced a Mw 4.0 and 4.3 induced earthquake sequence...
The discussion about the impact of the construction of new transport infrastructure on economic growth has been going on in scientific journals for decades. The objective of the article is to assess the importance of the development of transport infr...
Electric vehicle (EV) adoption is rising rapidly, creating growing challenges for charging infrastructure planning, energy demand management, and grid stability. However, most existing studies rely on single-domain data, such as behavioral charging s...
The objective of this article is the definition of an algorithm aimed to settle the sequence of implementation of Information Technology Infrastructure Library (ITIL) processes that should be followed in the technology departments for its proper mana...
The most important standard in technology services management is the Information Technology Infrastructure Library (ITIL). The literature review developed shows that one of the most important questions to answer is finding the sequence of processes t...
One of the main points when implementing the Information Technology Infrastructure Library (ITIL) is which order the processes must be implemented. In the systematic literature review (SLR) developed, it is possible to find references about strategie...
In this paper, we seek to establish ‘sequencing economics’ in an architectural theory on agglomerations that are comprised of various segments, such as infrastructure, institutions and human resources. The sequencing of such segments is b...
One of the key elements to consider in business management is the management of IT (Information Technology) departments by implementing processes as described in the ITIL (Information Technology Infrastructure Library) standard. This is particularly...
Among all economically important plant species in the world, grapevine (Vitis vinifera L.) is the most cultivated fruit plant. It has a significant impact on the economies of many countries through wine and fresh and dried fruit production. In recent...
Over the past years, NGS has become a crucial workhorse for open-view pathogen diagnostics. Yet, long turnaround times result from using massively parallel high-throughput technologies as the analysis can only be performed after sequencing has finish...
Autosomal short tandem repeat (STR) markers remain the cornerstone of modern forensic genetics, providing exceptional power for individualization, kinship verification, and reconstruction of complex investigative cases. Over the last decade, the fiel...
Bacterial culture and biochemical testing (CBtest) have been the cornerstone of pathogen identification in the diagnostic microbiology laboratory. With the advent of Sanger sequencing and later, next-generation sequencing, 16S rRNA next-generation se...
Affordable, sensitive, and scalable technologies are needed for monitoring antiretroviral treatment (ART) success with the goal of eradicating HIV-1 infection. This review discusses use of Sanger sequencing and next generation sequencing (NGS) method...
In recent years, the use of Cloud infrastructures for data processing has proven useful, with a computing potential that is not affected by the limitations of a local infrastructure. In this context, Serverless computing is the fastest-growing Cloud...
The introduction of next-generation sequencing (NGS) in the molecular diagnostic armamentarium is deeply changing pathology practice and laboratory frameworks. NGS allows for the comprehensive molecular characterization of neoplasms, in order to prov...
The extensive genetic diversity of HIV-1 represents a major challenge to public health interventions, treatment, and successful vaccine design. This challenge is particularly pronounced in the Middle East and North Africa (MENA) region, where limited...
Diagnosing and treating many infectious diseases depends on correctly identifying the causative pathogen. Characterization of pathogen-specific nucleic acid sequences by PCR is the most sensitive and specific method available for this purpose, althou...
The increase in memory and in network traffic used and caused by new sequenced biological data has recently deeply grown. Genomic projects such as HapMap and 1000 Genomes have contributed to the very large rise of databases and network traffic relate...
The imperative for building managers, in the face of high-density urban environments, is to drive existing chiller plants to greater operational efficiency through the application of advanced technological interventions. The case for applying Supervi...
Whole-genome sequencing (WGS) is central to outbreak response for high-consequence ribonucleic acid (RNA) viruses, but useful genomes depend on workflow design, sample quality, biosafety, diagnostic breadth, infrastructure, and bioinformatics as much...
In modern societies, the rampant growth of the Internet, both on the technological and social level, has created fertile ground for the emergence of new types of risk. On top of that, it enhances pre-existing threats by offering new means for accessi...
Companies such as Netflix increasingly use the cloud to deploy their business processes. Those processes often involve partnerships with other companies, and can be modeled as workflows where the owner of the data at risk interacts with contractors t...
The detection of drug resistance mutations (DRMs) in minor viral populations is of potential clinical importance. However, sophisticated computational infrastructure and competence for analysis of high-throughput sequencing (HTS) data lack at most di...
Public sports facilities have the potential to improve their functions as active living infrastructures (ALIs) in combination with bicycle lanes and green spaces. A favorable sequence of exercise intensities in different scenes is important for indiv...
Background: Liquefied natural gas (LNG) distribution in archipelagic regions involves complex trade-offs between transportation, infrastructure investment, and contractual arrangements. While most optimisation studies focus on seller-managed Delivery...
The Industry 4.0 idea influences the development of both charging stations and electromobility development, due to its emphasis on device communication, cooperation, and proximity. Therefore, in electromobility development, growing attention is paid...
Salmonella surveillance and outbreak management is a key function of public health. Laboratories are shifting from antigenic serotype determination to molecular methods including microarray or whole genome sequencing technologies. The objective of th...
The advent of next-generation sequencing (NGS) has provided unprecedented insight into the molecular complexity of pancreatic ductal adenocarcinoma (PDAC). This has led to the emergence of biomarker-driven treatment paradigms that challenge empiric t...
The increasing digitalization of energy transmission and distribution infrastructures has made industrial control systems (ICS), and especially IEC 61850-based communication structures, critical. IEC 61850 performs protection and control functions in...
The use of fiber-reinforced polymer (FRP) composite materials are continuously growing in civil infrastructure due to their high strength, low weight, and manufacturing flexibility. However, FRP is characterized by sudden failure and lacks ductility....
Hand gestures are a natural and efficient means to control systems and are one of the promising but challenging areas of human–machine interaction (HMI). We propose a system to recognize gestures by processing interrupted patterns of light in a...
Nanopore-based sequencing has emerged as a revolutionary tool for animal pathogen genomics, offering capabilities unattainable with Sanger and next-generation sequencing (NGS). Despite rapid technical progress, routine veterinary deployment still fac...
Tourism performance often depends on the joint provision of built (“hard”) and environmental (“green”) infrastructure, yet their combined effects are not well established. Using official data for Saudi Arabia’s 13 region...
This study investigates the transition toward green transportation in Hanoi through a culture-centered perspective by integrating the Culture Tower (KAUC) framework with PLS-SEM analysis. Using survey data from 172 urban residents, the research exami...
Open data is often presented as a democratising condition for digital heritage, yet this assumption overlooks the unequal infrastructures and classificatory regimes through which data are produced, stored, and made visible. The article introduces the...
The widespread integration of inverter-based distributed generators (IIDGs) severely limits the adaptability of conventional three-step overcurrent protection in distribution networks (DNs). To address weak rural infrastructure and incomplete post-fa...
This review chronicles the evolution of human microbiome research, tracing its trajectory from early descriptive studies to the current era of large multi-omics repositories. Technological advancements, such as high-throughput 16S rRNA sequencing and...
With the widespread adoption of electric vehicles, predicting user charging consumption can enhance the operational efficiency of charging infrastructure. However, differences in user charging habits result in charging station operators obtaining dat...
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