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8,210 Results Found

  • Article
  • Open Access
1 Citations
3,098 Views
15 Pages

20 August 2024

Fundamental movement skills (FMSs) are essential building blocks for children’s physical development and future participation in physical activities. While early childhood curriculum frameworks recognize the importance of teaching FMSs, little...

  • Article
  • Open Access
33 Citations
6,196 Views
16 Pages

Interpersonal Conflict, School Connectedness and Depressive Symptoms in Chinese Adolescents: Moderation Effect of Gender and Grade Level

  • Guan-Hao He,
  • Esben Strodl,
  • Wei-Qing Chen,
  • Fan Liu and ,
  • Alimila Hayixibayi and
  • Xiang-Yu Hou
  • + 1 author+ 0 author

This study examined the associations of interpersonal conflict and school connectedness with depressive symptoms in Chinese adolescents. A cross-sectional study was conducted among 6576 adolescents in Shenzhen, China. Participants completed a battery...

(This article belongs to the Section Mental Health)
  • Article
  • Open Access
9 Citations
3,754 Views
23 Pages

25 June 2022

This paper presents a hybrid level set method (HLSM) to design novelty functionally graded structures (FGSs) with complex macroscopic graded patterns. The hybrid level set function (HLSF) is constructed to parametrically model the macro unit cells by...

(This article belongs to the Special Issue Mechanical Metamaterials: Optimization and New Design Ideas)
  • Article
  • Open Access
10 Citations
3,133 Views
28 Pages

14 July 2023

The technical research on determining the drought limit water level can be used as an important basis for starting the emergency response of drought resistance in the basin and guiding the drought resistance scheduling of water conservancy projects....

(This article belongs to the Section Water Resources Management, Policy and Governance)
  • Article
  • Open Access
10 Citations
4,635 Views
21 Pages

Deep Neural Networks for HER2 Grading of Whole Slide Images with Subclasses Levels

  • Anibal Pedraza,
  • Lucia Gonzalez,
  • Oscar Deniz and
  • Gloria Bueno

23 February 2024

HER2 overexpression is a prognostic and predictive factor observed in about 15% to 20% of breast cancer cases. The assessment of its expression directly affects the selection of treatment and prognosis. The measurement of HER2 status is performed by...

(This article belongs to the Section Evolutionary Algorithms and Machine Learning)
  • Article
  • Open Access
4 Citations
3,854 Views
11 Pages

Food Trying and Liking Related to Grade Level and Meal Participation

  • Jennifer Hanson,
  • Janelle Elmore and
  • Marianne Swaney-Stueve

School-based child nutrition programs provide students with meals and snacks that align with guidelines for a healthy eating pattern. However, participation is not universal, and research on the determinants of food selection is needed to improve sch...

(This article belongs to the Special Issue Child Nutrition Management)
  • Article
  • Open Access
1 Citations
596 Views
45 Pages

RubricAdapt-LLM: Measuring Criterion-Level Adaptation and Score Shifts Under Alternative Grading Rubrics

  • Catalin Anghel,
  • Andreea Alexandra Anghel,
  • Adina Cocu,
  • Marian Viorel Craciun and ,
  • Simona Moldovanu,
  • Mihai Vlase and
  • Cristian Sandu
  • + 2 authors+ 0 author

10 September 2026

Background: Large language models are increasingly used for rubric-based grading, but it remains unclear whether they adapt selectively when criterion weights change while the response, criterion definitions, and total score remain fixed. This study...

  • Article
  • Open Access
1 Citations
3,844 Views
12 Pages

15 May 2024

This study examined the aesthetic developmental characteristics of contour features (curved and sharp corners) among children and adolescents with different levels (high and low) of visual aesthetic sensitivity in three grades (4, 6, and 8). The resu...

(This article belongs to the Section Cognition)
  • Article
  • Open Access
1 Citations
799 Views
14 Pages

Physical Activity, Academic Stress, and Motivation in Physical Education: A Cross-Sectional Analysis by Sex and Grade Level

  • Borys Bismark León-Reyes,
  • Dilan Galeano-Rojas,
  • Marcos Granados-Moreno,
  • Josivaldo de Souza-Lima and ,
  • Claudio Farías-Valenzuela,
  • Antonio Castillo-Paredes and
  • Pedro Valdivia-Moral
  • + 2 authors+ 0 author

Objectives: The aim of the present study was to analyze the relationships among physical activity, academic stress, and motivation in Physical Education, as well as to determine differences according to sex and grade level. Methods: A total of 310 se...

(This article belongs to the Special Issue Exploring the Link Between Physical Activity, Mental Health, and Well-Being)
  • Article
  • Open Access
6 Citations
2,644 Views
14 Pages

We investigated associations between polysubstance use and behavioral problems among adolescents. Because substance use becomes more developmentally normative with age, we examined whether polysubstance use was less likely to co-occur with behavioral...

(This article belongs to the Section Behavioral and Mental Health)
  • Article
  • Open Access
3,471 Views
14 Pages

Nomophobia Levels in Turkish High School Students: Variations by Gender, Physical Activity, Grade Level and Smartphone Use

  • Piyami Çakto,
  • İlyas Görgüt,
  • Amayra Tannoubi,
  • Michael Agyei and ,
  • Medina Srem-Sai,
  • John Elvis Hagan,
  • Oğuzhan Yüksel and
  • Orhan Demir
  • + 3 authors+ 0 author

1 August 2025

The rapidly changing dynamics of the digital age reshape the addiction relationship that high school students establish with technology. While smartphones remove boundaries in terms of communication and access to information, their usage triggers a s...

  • Article
  • Open Access
20 Citations
3,802 Views
25 Pages

A Low-Grade Road Extraction Method Using SDG-DenseNet Based on the Fusion of Optical and SAR Images at Decision Level

  • Jinglin Zhang,
  • Yuxia Li,
  • Yu Si,
  • Bo Peng and ,
  • Fanghong Xiao,
  • Shiyu Luo and
  • Lei He
  • + 2 authors+ 0 author

15 June 2022

Low-grade roads have complex features such as geometry, reflection spectrum, and spatial topology in remotely sensing optical images due to the different materials of those roads and also because they are easily obscured by vegetation or buildings, w...

(This article belongs to the Special Issue Synthetic Aperture Radar (SAR) Meets Deep Learning)
  • Article
  • Open Access
6 Citations
4,906 Views
11 Pages

Changes in Nurse Staffing Grades of Korean Hospitals during COVID-19 Pandemic

  • Young-Taek Park,
  • JeongYun Park,
  • Ji Soo Jeon,
  • Young Jae Kim and
  • Kwang Gi Kim

The global COVID-19 pandemic is creating challenges to manage staff ratios in clinical units. Nurse staffing level is an important indicator of the quality of care. This study aimed to identify any changes in the nurse staffing levels in the general...

  • Article
  • Open Access
11 Citations
3,491 Views
14 Pages

Little is known about the longitudinal trajectories and associations regarding physical activity (PA), physical fitness (PF), and cognitive skills in childhood. Accelerometer-based PA, sedentary behavior (SB), PF, and cognitive skills were measured i...

(This article belongs to the Special Issue Physical Education in Early Childhood)
  • Systematic Review
  • Open Access
5 Citations
3,214 Views
19 Pages

19 June 2025

The increasing demand for efficient, sustainable, and coordinated construction practices has intensified interest in the integration of digital tools such as Building Information Modelling (BIM) with modularization and standardization strategies. Thi...

(This article belongs to the Collection Construction Management – Future Innovations, Methods, Techniques and Technologies)
  • Article
  • Open Access
35 Citations
6,393 Views
22 Pages

27 January 2015

In order to realize the non-contact measurement of ceramic insulator contamination severity, a method based on feature level fusion of infrared (IR) and ultraviolet (UV) image information is proposed in this paper. IR and UV images of artificially po...

  • Article
  • Open Access
7 Citations
4,469 Views
13 Pages

School-related stress and burnout can have serious consequences for students’ well-being and academic outcomes. However, there are few studies that assess the prevalence of school burnout, especially in Germany. The present study aims to determ...

  • Article
  • Open Access
4 Citations
3,196 Views
19 Pages

New Insights Reached via Graded-Interfaces Modeling: How High-Power, High-Efficiency Mid-Infrared QCLs Work

  • Dan Botez,
  • Suraj Suri,
  • Huilong Gao,
  • Thomas Grange and ,
  • Jeremy D. Kirch,
  • Luke J. Mawst and
  • Robert A. Marsland
  • + 2 authors+ 0 author

21 January 2025

Graded-interfaces modeling unveils key features of high-power, high-efficiency quantum-cascade lasers (QCLs): direct resonant-tunneling injection from a prior-stage, low-energy state into the upper-laser (ul) level, over a wide (~50 nm) multiple-barr...

(This article belongs to the Special Issue Photonics: 10th Anniversary)
  • Article
  • Open Access
18 Citations
11,240 Views
17 Pages

10 September 2012

I define information from a philosophical perspective as a category that indicates the presence of indirect existence, which is a self-display by material entities (with direct existence) of the status and trajectory of that existence. In this paper,...

(This article belongs to the Section Information Theory and Methodology)
  • Article
  • Open Access
1 Citations
4,361 Views
6 Pages

The purpose of this study was to evaluate the impact of biofeedback therapy on evacuation difficulty level and the pain grade during defecation of elderly female patients with dyssynergic defecation. With this aim, after one month of initial assessme...

  • Article
  • Open Access
3 Citations
4,931 Views
14 Pages

Chinese Virtues and Resilience among Students in Hong Kong

  • Xiaoxue Kuang,
  • John Chi-Kin Lee and
  • Junjun Chen

Character strengths and training have a great impact on students’ whole-person development. This study examined the applicability of the Chinese virtues questionnaire (CVQ) and the relationships between students’ perceptions of virtues an...

(This article belongs to the Special Issue Well-Being and Health in Education: Challenges, Chances, and Change)
  • Review
  • Open Access
3 Citations
2,683 Views
20 Pages

Next-Generation S3-Level Clinical Practice Guidelines in Periodontology: Methodology, Current Evidence, and Future Directions

  • Nada Tawfig Hashim,
  • Ayman Ahmed,
  • Azza A. Abushama,
  • Salma Musa Adam Abduljalil and ,
  • Bakri Gobara Gismalla and
  • Muhammed Mustahsen Rahman
  • + 1 author+ 0 author

15 January 2026

Background: S3-level clinical practice guidelines represent the highest standard of evidence-based healthcare, integrating systematic reviews, formal evidence grading, and structured expert consensus. In periodontology, current S3-level guidelines pr...

  • Article
  • Open Access
1 Citations
568 Views
40 Pages

4 June 2026

Highway–rail grade crossing (HRGC) safety analysis is often based on raw incident counts or site-level models that do not adequately control for regional crossing-density exposure and frequently ignore spatial dependence. This limits the abilit...

(This article belongs to the Special Issue Algorithms for Smart Cities (3rd Edition))
  • Article
  • Open Access
8 Citations
7,116 Views
12 Pages

2 March 2020

This study identified the relational paths between children’s ego function and fear of negative evaluation affecting academic failure tolerance across three grades. The ego function consisted of four factors: competence, initiative, resilience,...

(This article belongs to the Special Issue Selected Papers from the Eurasian Conference on Educational Innovation 2020)
  • Article
  • Open Access
10 Citations
4,446 Views
13 Pages

Iron Levels and Markers of Inflammation in a Population of Adults with Severe Obesity, a Cross-Sectional Study

  • Daniela Laudisio,
  • Giulia de Alteriis,
  • Claudia Vetrani,
  • Sara Aprano and ,
  • Gabriella Pugliese,
  • Francesca Zumbolo,
  • Annamaria Colao and
  • Silvia Savastano
  • + 3 authors+ 0 author

6 November 2023

Low-grade chronic inflammation linked to obesity can lead to alterations in biomarkers of iron status. The aim of this study was to investigate the primary determinant of serum iron levels among anthropometric measurements, body fat, and serum biomar...

(This article belongs to the Special Issue The Effect of Nutritional Aspect on Obesity and Hypertension)
  • Article
  • Open Access
768 Views
20 Pages

5 June 2026

This study used a Cross-Lagged Panel Network model to examine prospective longitudinal associations among dimensions of adolescent mental health and differences in these associations across gender and grade levels. A total of 3610 Chinese adolescents...

(This article belongs to the Section Educational Psychology)
  • Article
  • Open Access
56 Citations
6,269 Views
17 Pages

Comparison of SVM, RF and ELM on an Electronic Nose for the Intelligent Evaluation of Paraffin Samples

  • Hong Men,
  • Songlin Fu,
  • Jialin Yang,
  • Meiqi Cheng and ,
  • Yan Shi and
  • Jingjing Liu
  • + 1 author+ 0 author

18 January 2018

Paraffin odor intensity is an important quality indicator when a paraffin inspection is performed. Currently, paraffin odor level assessment is mainly dependent on an artificial sensory evaluation. In this paper, we developed a paraffin odor analysis...

(This article belongs to the Section Chemical Sensors)
  • Article
  • Open Access
427 Views
24 Pages

2 September 2026

Rapid technological innovation and digitalization have intensified the demand for STEM-related skills, yet many educational systems face stagnant or declining student engagement in STEM, particularly in the later years of secondary education. This st...

(This article belongs to the Special Issue Innovative Learning Environments: Technology, Self-Regulated Learning, and Educational Design)
  • Article
  • Open Access
10 Citations
3,009 Views
23 Pages

23 October 2020

In recent years, the functionally graded materials (FGM) with cellular structure have become a hot spot in the field of materials research. For the continuously varying cellular structure in the layer-wise FGM, the connection of gradient cellular str...

(This article belongs to the Special Issue Homogenization Methods in Materials and Structures)
  • Article
  • Open Access
2 Citations
1,949 Views
19 Pages

Relevance of Social Medicine Skills and the Role of Teaching Formats in the Perception of Medical Students: A Retrospective Trend Study

  • Sibylle Hildenbrand,
  • Joachim Graf,
  • Martina Michaelis,
  • Anke Wagner and ,
  • Susanne Völter-Mahlknecht,
  • Elisabeth Simoes and
  • Monika A. Rieger
  • + 2 authors+ 0 author

20 October 2025

During medical school, students in Germany acquire knowledge, abilities, competencies, and skills in social medicine. The aim of this study was to investigate how human medicine students perceive the relevance of selected social medical issues and th...

  • Article
  • Open Access
4 Citations
3,891 Views
20 Pages

22 July 2021

Although several biomarkers have been identified to predict the prognosis of lower-grade (Grade II/III) gliomas (LGGs), we still need to identify new markers to facilitate those well-known markers to obtain more accurate prognosis prediction in LGGs....

  • Article
  • Open Access
8 Citations
4,132 Views
24 Pages

27 April 2024

The intensity of the odor in food-grade paraffin waxes is a pivotal quality characteristic, with odor panel ratings currently serving as the primary criterion for its assessment. This study presents an innovative method for assessing odor intensity i...

(This article belongs to the Section Food Quality and Safety)
  • Article
  • Open Access
1 Citations
765 Views
11 Pages

Effect of High Pelvic Incidence on Fixation Failure in Single-Level Transforaminal Lumbar Interbody Fusion for Low-Grade Spondylolisthesis: A Retrospective Cohort Study

  • Koopong Siribumrungwong,
  • Sansern Satthanan,
  • Bunyaporn Wuttiworawanit,
  • Punnawit Pinitchanon and
  • Thongchai Suntharapa

22 April 2026

Objective: To investigate the association between pelvic incidence (PI) and fixation failure following single-level transforaminal lumbar interbody fusion (TLIF) for low-grade spondylolisthesis and to identify risk factors for pedicle screw loosening...

(This article belongs to the Special Issue Spine Surgery: Current Challenges and Future Perspectives)
  • Article
  • Open Access
8 Citations
1,819 Views
12 Pages

Background/Objectives: The increased accessibility of information has resulted in a rise in patients trying to self-diagnose and opting for self-medication, either as a primary treatment or as a supplement to medical care. Our objective was to evalua...

(This article belongs to the Special Issue Advancements in the Diagnostics and Management of Musculoskeletal Diseases)
  • Article
  • Open Access
8 Citations
3,622 Views
13 Pages

Numerical Analyses of Slope Stability Considering Grading and Seepage Prevention

  • Yuting Feng,
  • Fuyu Yan,
  • Lianrong Wu,
  • Guangyin Lu and
  • Taoying Liu

1 May 2023

The normal operation of the Yulangpei tailings reservoir is affected by landslide stability. In this paper, taking the main and side slopes near the dam bank of the Yulangpei ditch as an example, the water–soil coupling theory is applied to com...

(This article belongs to the Section Hydraulics and Hydrodynamics)
  • Article
  • Open Access
39 Citations
8,766 Views
14 Pages

28 February 2023

Internal short-circuit (ISC) faults are a common cause of thermal runaway in lithium-ion batteries (LIBs), which greatly endangers the safety of LIBs. Different LIBs have common features related to ISC faults. Due to the insufficient volume of acquir...

(This article belongs to the Collection Advances in Battery Energy Storage and Applications)
  • Article
  • Open Access
3 Citations
1,721 Views
13 Pages

29 May 2025

Background: Cervical dysplasia is a pre-malignant condition of the uterine cervix and is highly prevalent in Sub-Saharan Africa; especially affecting HIV-infected Black women. The anti-dysplastic effect of vitamin D hormones in cervical dysplasia is...

(This article belongs to the Section Obstetrics & Gynecology)
  • Article
  • Open Access
450 Views
22 Pages

1 September 2026

Early-warning systems based on Learning Management System (LMS) traces are commonly evaluated using random or unseen-student splits, even when deployment requires predictions in courses that were absent during model development. In this study, we dis...

(This article belongs to the Special Issue Transformative Approaches in Education: Harnessing AI, Augmented Reality, and Virtual Reality for Innovative Teaching and Learning (2nd Edition))
  • Article
  • Open Access
7 Citations
2,674 Views
13 Pages

Dual-Level Augmentation Radiomics Analysis for Multisequence MRI Meningioma Grading

  • Zongyou Cai,
  • Lun M. Wong,
  • Ye Heng Wong,
  • Hok Lam Lee and ,
  • Kam Yau Li and
  • Tiffany Y. So
  • + 1 author+ 0 author

17 November 2023

Background: Preoperative, noninvasive prediction of meningioma grade is important for therapeutic planning and decision making. In this study, we propose a dual-level augmentation strategy incorporating image-level augmentation (IA) and feature-level...

(This article belongs to the Special Issue Advances in Diagnosis and Differentiation in Head and Neck and Neuro Oncology)
  • Article
  • Open Access
2 Citations
4,001 Views
27 Pages

11 February 2025

This study validates and adapts the Grade Retention Survey for Chilean fourth-grade school teachers, focusing on their beliefs about the consequences of grade retention. A questionnaire of 17 items was administered to 4297 fourth-grade elementary sch...

  • Article
  • Open Access
3 Citations
2,763 Views
14 Pages

Serum Zinc Level Grading System: A Useful Model for Composite Hepatic Events in Hepatitis C Virus-Associated Liver Cirrhosis

  • Hiroki Nishikawa,
  • Hirayuki Enomoto,
  • Kazunori Yoh,
  • Yoshinori Iwata and ,
  • Yoshiyuki Sakai,
  • Kyohei Kishino,
  • Yoshihiro Shimono,
  • Naoto Ikeda,
  • Tomoyuki Takashima and
  • Shuhei Nishiguchi
  • + 12 authors+ 7 authors

28 February 2020

We aimed to clarify the impact of the serum zinc (Zn) level grading system proposed by the Japanese society of clinical nutrition (JSCN: 80 μg/dL ≤ serum Zn level < 130 μg/dL (type A), 60 μg/dL ≤ serum Zn level < 80 μg/dL (typ...

(This article belongs to the Section Gastroenterology & Hepatopancreatobiliary Medicine)
  • Article
  • Open Access
12 Citations
8,111 Views
8 Pages

Non-Pulse-Leakage 100-kHz Level, High Beam Quality Industrial Grade Nd:YVO4 Picosecond Amplifier

  • Zhenao Bai,
  • Zhenxu Bai,
  • Zhijun Kang,
  • Fuqiang Lian and ,
  • Weiran Lin and
  • Zhongwei Fan
  • + 1 author+ 0 author

14 June 2017

A non-pulse-leakage optical fiber pumped 100-kHz level high beam quality Nd:YVO4 picosecond amplifier has been developed. An 80 MHz, 11.5 ps mode-locked picosecond laser is used as the seed with single pulse energy of 1 nJ. By harnessing the double β...

(This article belongs to the Special Issue Solid State Lasers Materials, Technologies and Applications)
  • Article
  • Open Access
11 Citations
4,192 Views
20 Pages

Biomarkers in Adult-Type Diffuse Gliomas: Elevated Levels of Circulating Vesicular Heat Shock Protein 70 Serve as a Biomarker in Grade 4 Glioblastoma and Increase NK Cell Frequencies in Grade 3 Glioma

  • Philipp Lennartz,
  • Dennis Thölke,
  • Ali Bashiri Dezfouli,
  • Mathias Pilz and ,
  • Dominik Lobinger,
  • Verena Messner,
  • Hannah Zanth,
  • Karen Ainslie,
  • Morteza Hasanzadeh Kafshgari and
  • Gabriele Multhoff
  • + 11 authors+ 6 authors

The presence of circulating Hsp70 levels and their influence on the immunophenotype of circulating lymphocyte subsets were examined as diagnostic/prognostic biomarkers for the overall survival (OS) in patients with IDH-mutant WHO grade 3 oligodendrog...

(This article belongs to the Special Issue Establishment of State-of-the-Art Methods/Techniques and Identification of Novel Biomarkers in Brain Tumor Diagnosis)
  • Article
  • Open Access
19 Citations
5,055 Views
20 Pages

A Field Calibration Solution to Achieve High-Grade-Level Performance for Low-Cost Dual-Frequency GNSS Receiver and Antennas

  • Andreas Krietemeyer,
  • Hans van der Marel,
  • Nick van de Giesen and
  • Marie-Claire ten Veldhuis

15 March 2022

Low-cost dual-frequency receivers and antennas have created opportunities for a wide range of new applications, in regions and disciplines where traditional GNSS equipment is unaffordable. However, the major drawback of using low-cost antenna equipme...

(This article belongs to the Special Issue Advances in GNSS Positioning and GNSS Remote Sensing)
  • Article
  • Open Access
138 Views
26 Pages

The UFMylation Machinery Is a Protein-Level Co-Expression Module Uncoupled from the Transcriptome: Evidence from High-Grade Serous Ovarian Cancer

  • Zhi Wang,
  • Yingge Li,
  • Ming Hu,
  • Shouqi Huang and ,
  • Hongyang Xue,
  • Suting Li and
  • Jie Min
  • + 2 authors+ 0 author

Background: UFMylation is an evolutionarily conserved ubiquitin-like modification catalyzed by an enzymatic cascade comprising UBA5 (E1), UFC1 (E2), and UFL1 (E3). UFL1 acquires catalytic activity only upon assembly with DDRGK1 and CDK5RAP3 into a te...

(This article belongs to the Special Issue AI/Machine Learning-Driven Multi-Omics Research in Oncology)
  • Article
  • Open Access
7 Citations
2,590 Views
11 Pages

The Role of Consecutive Plasma Copeptin Levels in the Screening of Delayed Cerebral Ischemia in Poor-Grade Subarachnoid Hemorrhage

  • Jong Kook Rhim,
  • Dong Hyuk Youn,
  • Bong Jun Kim,
  • Youngmi Kim and ,
  • Sungeun Kim,
  • Heung Cheol Kim and
  • Jin Pyeong Jeon
  • + 2 authors+ 0 author

25 March 2021

The prognostic value of copeptin in subarachnoid hemorrhage (SAH) has been reported, but the prognosis was largely affected by the initial clinical severity. Thus, the previous studies are not very useful in predicting delayed cerebral ischemia (DCI)...

(This article belongs to the Section Medical Research)
  • Article
  • Open Access
12 Citations
5,987 Views
12 Pages

CA-125 Levels Are Predictive of Survival in Low-Grade Serous Ovarian Cancer—A Multicenter Analysis

  • Christoph Wohlmuth,
  • Vladimir Djedovic,
  • Susanne K. Kjaer,
  • Allan Jensen and ,
  • Rosalind Glasspool,
  • Patricia Roxburgh,
  • Anna DeFazio,
  • Sharon E. Johnatty,
  • Penelope M. Webb and
  • Taymaa May
  • + 24 authors+ 19 authors

13 April 2022

Objective: Studies on low-grade serous ovarian cancer (LGSC) are limited by a low number of cases. The aim of this study was to define the prognostic significance of age, stage, and CA-125 levels on survival in a multi-institutional cohort of women w...

  • Article
  • Open Access
6 Citations
3,233 Views
13 Pages

Exploring the Control of PARP1 Levels in High-Grade Serous Ovarian Cancer

  • Giuseppina Raspaglio,
  • Marianna Buttarelli,
  • Natalia Cappoli,
  • Alessandra Ciucci and ,
  • Anna Fagotti,
  • Giovanni Scambia and
  • Daniela Gallo
  • + 2 authors+ 0 author

18 April 2023

High-grade serous ovarian cancer (HGSOC) is a leading cause of mortality from gynecologic malignancies worldwide. Although a transformative improvement has been shown with the introduction of PARP (poly(ADP-ribose) polymerase) inhibitors, the emergen...

(This article belongs to the Special Issue Advances in Ovarian Cancer Research and Treatment)
  • Article
  • Open Access
410 Views
30 Pages

Background: Hypertensive retinopathy (HR) is an early marker of hypertension-related end-organ damage, and multi-grade classification is limited by overlap between the early stages. No prior study has reported edge-deployable HR grading from optical...

(This article belongs to the Special Issue Application of Deep Learning in Medical Image Classification and Segmentation for Precise Disease Diagnosis)
  • Article
  • Open Access
1 Citations
3,560 Views
15 Pages

Association of Klotho Gene Polymorphism and Serum Level of α Klotho Protein with Different Tumor Grades, Overall Survival and Cytokine Profile in Glioma Patients

  • Eszter Zsemlye,
  • Vladimira Durmanova,
  • Kristina Kluckova,
  • Jan Kozak and ,
  • Boris Rychly,
  • Marian Svajdler,
  • Viktor Matejcik,
  • Monika Homolova,
  • Juraj Steno and
  • Maria Bucova
  • + 6 authors+ 1 author

Gliomas are the most common and lethal forms of malignant brain tumors. We attempted to identify the role of the aging-suppressor Klotho gene and Klotho protein in the immunopathogenesis of gliomas. We examined Klotho genetic variants by PCR-RFLP and...

(This article belongs to the Special Issue Biomechanics and Molecular Research on Glioblastoma)

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