Background: The diagnosis of lymphoma requires surgical specimens to perform morphological evaluation, immunohistochemical and molecular analyses. Ultrasound-guided fine needle aspiration may represent an appropriate first approach to obtain cytologi...
Histological evidence is essential for diagnosing malignant biliary strictures. However, conventional brush cytology remains the primary method used worldwide, despite its low diagnostic sensitivity and accuracy, as it is technically easy, rapid, and...
Circulating tumor cells (CTCs) are extremely low-frequency cells in the bloodstream. As those cells have detached from the primary tumor tissues and it circulates throughout the whole body, they are considered as promising diagnostic biomarkers for c...
Malignant pleural effusion (MPE) can accompany advanced lung adenocarcinoma. Recent studies suggest that MPE could contain a heterogeneous subpopulation of cells with stem-like properties, such as tumorigenicity and self-renewal, indicating that they...
Purpose: The purpose of this study was to examine the diagnostic accuracy of the cell block (CB) method and clinical features affecting it in patients with vitreoretinal lymphoma (VRL). Methods: This study enrolled 38 eyes in 33 VRL patients, and 7 e...
Primary oral diffuse large B cell lymphoma (DLBCL) is rare and the differential diagnosis is difficult due to its low incidence and nonspecific symptoms, which resemble those of common oral diseases in the initial clinical setting. We aimed to discus...
The identification of anticancer therapies using next-generation sequencing (NGS) is necessary for the treatment of cholangiocarcinoma. NGS can be easily performed when cell blocks (CB) are obtained from bile stored overnight. We compared NGS results...
The specimen collection and subsequent pathological diagnosis of malignant biliary stricture (MBS) are difficult. This study aimed to determine whether the cell block (CB) method using overnight-stored bile is useful in the diagnosis of MBS. This tri...
This work aims to study and analyze sustainability improvement in urban and road transportation by using a hybrid power system for electric vehicles consisting of a dual low- and high-rate operation lithium battery block and a fuel cell. The proposed...
Feline infectious peritonitis (FIP) can be overlooked in older cats with competing causes of effusion. An older female domestic shorthair cat with hyperthyroidism and a hypertrophic cardiomyopathy phenotype developed abdominal effusion in December 20...
Like batteries, fuel cells provide an inherently clean source of energy with no adverse environmental impact during operation. The utilization of methanol as a fuel is advantageous: it has an energy density of about 6 kWh/kg, which is, much higher th...
Background/Objectives: Risk stratification of thyroid nodules classified as categories III–IV in The Bethesda System for Reporting Thyroid Cytopathology (TBSRTC) remains challenging. This study evaluated the incremental diagnostic value of cell...
At least 12 serotypes of ‘atypical’ bluetongue virus (BTV-25 to BTV-36) have been identified to date. These atypical serotypes fail to infect/replicate in Culicoides-derived cell lines and/or adult Culicoides vectors and hence can no long...
Pancreatic cancer is one of the deadliest malignancies, characterized by late-stage diagnosis and limited treatment options. Comprehensive genomic profiling plays an important role in understanding the molecular mechanisms underlying the disease and...
We report the synthesis of poly[(3-hexylthiophene)-block-(3-(4,4,5,5,6,6,7,7,7-nonafluoroheptyl)thiophene)], P(3HT-b-3SFT), carried out by the Grignard Metathesis Method (GRIM). The copolymers composition was determined by 1H and 19F NMR spectroscopi...
The block layer situated between the active material and electrode in photoelectrochemical devices serves as a critical component for performance enhancement. Using dye-sensitized solar cells as a representative model, this review systematically exam...
Among the emerging photovoltaic technologies, perovskite solar cells (PSCs) are the most promising ones with efficiencies close to crystalline silicon. However, stability and reliability issues are still a limit for future applications of this techno...
Classical swine fever (CSF), caused by the classical swine fever virus (CSFV), is an acute, febrile, and highly contagious disease that has led to significant economic losses in the global swine industry. Although the attenuated lapinized CSF vaccine...
Cytopathological examination is one of the main examinations for pleural effusion, and especially for many patients with advanced cancer, pleural effusion is the only accessible specimen for establishing a pathological diagnosis. The lack of cytopath...
Fullerene derivatives have been widely used for conventional acceptor materials in organic photovoltaics (OPVs) because of their high electron mobility. However, there are also considerable drawbacks for use in OPVs, such as negligible light absorpti...
The main efficiency loss is caused by an intensive recombination process at the interface of fluorine-doped tin oxide (FTO) and electrolyte in dye-sensitized solar cells. Electrons from the photoanode can be injected back to the redox electrolyte and...
16 September 2026
Magnetic cell assembly has emerged as a powerful biofabrication strategy that uses externally applied magnetic fields to manipulate and organize living cells with spatial control, enabling the fabrication of scaffold-free multicellular constructs whi...
The hole blocking layer plays an important role in suppressing recombination of holes and electrons between the perovskite layer and fluorine-doped tin oxide (FTO). Morphological defects, such as cracks, at the compact TiO2 hole blocking layer due to...
In this study, a singly diagonally implicit block backward differentiation formula (SDIBBDF) was proposed to approximate solutions for a dynamical HIV infection model of CD
It is widely recognized that fullerene derivatives show several advantages as n-type materials in photovoltaic applications. However, conventional [6,6]-phenyl-C61-butyric acid methyl ester (PCBM) exhibits weak absorption in the visible region, and p...
This is a review of approaches to the design of peptides and small molecules that selectively block the oncogenic RAS-p21 protein in ras-induced cancers. Single amino acid substitutions in this protein, at critical positions such as at Gly 12 and Gln...
In this work, chemical bath-deposited cadmium sulfide (CdS) thin films were employed as an alternative hole-blocking layer for inverted poly(3-hexylthiophene) (P3HT) and phenyl-C61-butyric acid methyl ester (PCBM) bulk heterojunction solar cells. CdS...
Canine lymphoma (CL) is a heterogeneous neoplasm with varying prognoses, and Ki67 expression is a key marker for assessing tumor proliferation. This study aimed to compare Ki67 immunostaining in cytology smears (PSCS) and cell blocks (CBs) of canine...
(1) Background: The Milan System for Reporting Salivary Gland Cytopathology (MSRSGC) was introduced in 2018, bringing an organ-specific classification system for salivary gland cytopathology. The aim of present study is to evaluate the MSRSGC prospec...
Standard toxicity tests might not be fully adequate for evaluating nanomaterials since their unique features are also responsible for unexpected interactions. The in vitro cytokinesis-block micronucleus (CBMN) test is recommended for genotoxicity tes...
Immunolabeling on Romanowsky-stained cytology (RSC) slides can be used, although there is limited evidence of its suitability for phenotyping canine and feline lymphomas. A comparison with matched cell blocks (CB) is missing. Immunolabeling on RSC an...
Aggressive metastatic progression often develops in bladder cancer patients with acquired cisplatin or gemcitabine resistance. The potential of the natural isothiocyanates allyl-isothiocyanate (AITC), butyl-isothiocyanate (BITC), and phenylethyl-isot...
The collection of solar energy in chemical bonds via dye-sensitized photoelectrosynthesis cells (DSPECs) is a reliable solution. Herein, atomic layer deposition (ALD) introduced ultrathin blocking layers (BLs) between a mesoporous TiO2 membrane and f...
Equine bone blocks have osteogenic effects promoting bone regeneration with biocompatibility and osteoconductivity capacity. Human dental pulp stem cells (hDPSCs) can differentiate into osteoblasts enhancing biomineralization with such scaffolds. Mel...
We recently characterised the NUP98-HOXD13 (NHD13) mouse as a model of T-cell pre-leukaemia, featuring thymocytes that can engraft in recipient animals and progress to T-cell acute lymphoblastic leukaemia (T-ALL). However, loss of this engraftment ab...
With half-cut photovoltaic (PV) modules being the dominant technology on the market, there is an increasing necessity for accurate modeling of this module type. Circuit simulators such as Simulink are widely used to study different topics regarding p...
Reperfusion after ischemia causes additional cellular damage, known as reperfusion injury, for which there is still no effective remedy. Poloxamer (P)188, a tri-block copolymer-based cell membrane stabilizer (CCMS), has been shown to provide protecti...
The cell-surface protein B cell maturation antigen (BCMA, CD269) has emerged as a promising target for CAR-T cell therapy for multiple myeloma. In order to create a novel BCMA CAR, we generated a new BCMA monoclonal antibody, clone 4C8A. This antibod...
Research on the budding yeast Saccharomyces cerevisiae has yielded fundamental discoveries on highly conserved biological pathways and yeast remains the best-studied eukaryotic cell in the world. Studies on the mitotic cell cycle and the discovery of...
Previous results have shown that infection with the cytoplasmic-replicating parainfluenza virus 5 mutant P/V-CPI- sensitizes cells to DNA damaging agents, resulting in the enhanced killing of airway cancer cells. Here, we have tested the hypothesis t...
Fibrosis is characterized by excessive production of disorganized collagen- and fibronectin-rich extracellular matrices (ECMs) and is driven by the persistence of myofibroblasts within tissues. A key protein contributing to myofibroblast differentiat...
In this work, we design and produce micron-sized fiber mats by blending poly(ε-caprolactone) (PCL) with small amounts of block copolymers poly(ethylene oxide)m-block-poly(ε-caprolactone)n (PEOm-b-PCLn) using electrospinning. Three dif...
17 March 2022
Introduction: Diagnosis of lung nodules is still under investigation. We use computed tomography scans and positron emission tomography in order to identify their origin. Patients and Methods: In our retrospective study, we included 248 patients with...
Background/Objectives: The rat osteosarcoma cell line UMR-106 is widely used for the study of bone cancer biology but it has not been well characterized with modern genomic methods. Methods: To better understand the biology of UMR-106 cells we used a...
The aim of this work was to study the initial events of Escherichia coli adhesion to polydimethylsiloxane, which is critical for the development of antifouling surfaces. A parallel plate flow cell was used to perform the initial adhesion experiments...
Poly(3-hexylthiophene)-block-polystyrene (P3HT-b-PS) was synthesized by Suzuki coupling reaction between P3HT and PS, prepared by Grignard metathesis polymerization and atom transfer radical polymerization (ATRP), respectively. The formation of block...
Despite the success of highly active antiretroviral therapy (HAART), integrated HIV-1 proviral DNA cannot be eradicated from an infected individual. HAART is not able to eliminate latently infected cells that remain invisible to the immune system. Vi...
The chromatin-remodeling protein ATRX, which is currently recognized as one of the key genome caretakers, plays an important role in oogenesis and early embryogenesis in mammals. ATRX distribution in the nuclei of mouse embryos developing in vivo and...
In 2019, streptoglutarimide H (SGH) was characterized as a new glutarimide from the secondary metabolites produced by a marine-derived actinomycete Streptomyces sp. ZZ741 and shown to have in vitro antiglioma activity. However, the antiproliferative...
Semantic segmentation of Signet Ring Cells (SRC) plays a pivotal role in the diagnosis of SRC carcinoma based on pathological images. Deep learning-based methods have demonstrated significant promise in computer-aided diagnosis over the past decade....
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