Biological networks such as protein interaction networks, gene regulation networks, and metabolic pathways are examples of complex networks that are large graphs with small-world and scale-free properties. An analysis of these networks has a profound...
13 May 2021
Multiple studies have been conducted to identify the complex and diverse relationships between stream ecosystems and land cover. However, these studies did not consider spatial dependency inherent from the systemic structure of streams. Therefore, th...
Biological systems, characterized by their complex interplay of symmetry and asymmetry, operate through intricate networks of interacting molecules, weaving the elaborate tapestry of life. The exploration of these networks, aptly termed the “mo...
Nowadays, cluster analysis of biological networks has become one of the most important approaches to identifying functional modules as well as predicting protein complexes and network biomarkers. Furthermore, the visualization of clustering results i...
The increasing availability of transcriptomic data has created new opportunities for integrating gene expression studies across biological systems and conditions. However, differences in experimental design, sequencing platforms, and sample compositi...
Arthropod natural enemies—encompassing predators and parasitoids—form the backbone of sustainable agriculture, delivering irreplaceable ecosystem services via biological pest suppression. Driven by global demand for eco-friendly alternati...
Actinidia arguta, also known as mini kiwi (due to its small size) or hardy kiwi (due to its frost resistance), is becoming an increasingly popular fruit alongside its commercially older siblings, i.e., A. deliciosa (green kiwi fruit) and A. chinensis...
The aim of this work is to provide a critical review of plant furanocoumarins from different points of view, including their chemistry and biosynthetic pathways to their extraction, analysis, and synthesis, to the main biological activities found for...
Efficacy of Vitamin D supplements in depression is controversial, awaiting further literature analysis. Biological flaws in primary studies is a possible reason meta-analyses of Vitamin D have failed to demonstrate efficacy. This systematic review an...
Grapevine crown gall (GCG), which is caused by Allorhizobium vitis (=Rhizobium vitis) tumorigenic strains, is the most important disease of grapevine around the world. Previously, nonpathogenic A. vitis strains VAR03-1, ARK-1, ARK-2, and ARK-3 were i...
The panax genus is a widely used medicinal plant with good biological activity. As one of the main active components of the Panax genus, polysaccharides have various pharmacological effects. This review summarizes the latest research reports on ginse...
Biological technology allows us to invent new medical approaches, create effective food production methods and reserves and develop new materials for industrial production. There is a diversity of biological technology types, and different technologi...
Lead (Pb) is one of the most relevant contaminants due to its high toxicity, even at low concentrations. The growing need for research about real-time Pb analysis in the field has driven advancements in portable, sensitive, and automated analytical m...
Graph neural networks (GNNs) are increasingly used for medical imaging analysis and biological data modeling, where the integration of radiomics, topology, geometry, and generative artificial intelligence (AI) may improve representation learning from...
This paper presents a trial analysis of the relationship between taste and biological information obtained while eating strawberries (for a sensory evaluation). This study used the visual analog scale (VAS); we collected questionnaires used in previo...
Staphylococcus aureus is an important zoonotic pathogen that threatens public health, food safety, and livestock production. Bacteriophages are promising antibacterial agents for controlling antimicrobial-resistant S. aureus, but their biological pro...
Integrated solid waste management (ISWM) strategies are developed towards promoting sustainable approaches for handling waste. Recently, gasification and mechanical biological treatment (MBT) technologies were recognized as effective processes for tr...
In this study, we investigate the application of fractional calculus to the mathematical modeling of biological systems, focusing on fractional-order-in-time partial differential equations (FTPDEs). Fractional derivatives, especially those defined in...
The technological advantages that biosensors have over conventional technical sensors for odor detection and the role they play in the biological transformation have not yet been comprehensively analyzed. However, this is necessary for assessing thei...
28 January 2023
Cannabinoids are still the most consumed drugs of abuse worldwide. Despite being considered less harmful to human health, particularly if compared with opiates or cocaine, cannabis consumption has important medico-legal and public health consequences...
Conventional methods for transporting biological materials typically use dry ice or ice for preservation but often overlook important aspects of temperature monitoring and metrological control. These methods generally do not include temperature senso...
Predicting compounds with single- and multi-target activity and exploring origins of compound specificity and promiscuity is of high interest for chemical biology and drug discovery. We present a large-scale analysis of compound promiscuity including...
CD68 is a highly glycosylated transmembrane glycoprotein that belongs to the lysosome-associated membrane glycoprotein family and is involved in various immune processes. In this study, Megalobrama amblycephala CD68 (MaCD68) was cloned and chara...
Poplar (Populus × xiaohei T. S. Hwang et Liang) is an excellent model plant, with a known genome sequence, for studying woody plant developmental processes, such as seed germination. Here, we report the transcriptional profiling of poplar seeds...
Due to the high microbiological contamination of raw food materials and the increase in the incidence of multidrug-resistant bacteria, new methods of ensuring microbiological food safety are being sought. One solution may be to use bacteriophages (so...
Single-cell RNA-sequencing (scRNA-seq) is a recent high-throughput technique that can measure gene expression, reveal cell heterogeneity, rare and complex cell populations, and discover cell types and their relationships. The analysis of scRNA-seq da...
Chitooligosaccharide (COS), which is acknowledged for possessing multiple functions, is a kind of low-molecular-weight polymer prepared by degrading chitosan via enzymatic, chemical methods, etc. COS has comprehensive applications in various fields i...
Background/objectives: Melatonin has circadian, antioxidant, mitochondrial, and immunomodulatory functions, but human data linking relative melatonergic status to coordinated systemic biomarker burden remain limited. We examined this association and...
Background. Long-term outcomes of patients with infective endocarditis (IE) who received either a mechanical (MP) or biological prosthesis (BP) are conflicting. A meta-analysis of observational studies comparing the long-term outcomes of left-side IE...
Numerical analysis computational programs are applied to the research of biological tissues, which have complex forms. Continuous technological advance has facilitated the development of biomodels to evaluate biological tissues of different human bod...
In this work, a preliminary screening of the bioactivities of an ethanolic extract obtained from the leaves of Wollemia nobilis W.G.Jones, K.D.Hill & J.M.Allen was carried out to explore its potential pharmaceutical applications. In particular, t...
Objective: Update the available evidence comparing biologic disease-modifying antirheumatic drugs (bDMARDs) in combination with conventional synthetic disease-modifying antirheumatic drugs (CsDMARDs) to bDMARDs in monotherapy in patients with rheumat...
Biologists, philosophers, and mathematicians building upon Robert Rosen’s non-algorithmic theories of life using Relational Biology and Category Theory have continued to develop his theory and modeling approaches. There has been general agreeme...
Aristolochic acids are known for nephrotoxicity, and implicated in multiple cancer types such as hepatocellular carcinomas demonstrated by recent studies. Natural products that are analogues to aristolochic acids have been constantly isolated from or...
(1) Background: In recent years, the increasing emergence of multidrug-resistant pathogens in pig farms has begun to pose a severe threat to animal welfare and, by extension, public health. In this study, we aimed to explore the biological characteri...
The emission of volatile organic compounds (VOCs) has resulted in increasingly severe harm to the environment and human health. In recent years, biological methods have become the preferred technology for VOC removal due to their environmental friend...
Chronic spontaneous urticaria (CSU) is the most common phenotype of chronic urticaria. We compared treatment effects and safety profiles of the medications in patients with CSU. We searched PubMed, MEDLINE, and Web of Science for randomized control t...
Anthrax is a zoonotic infectious disease characterized by high lethality and transmissibility. Its spores are highly stable and can persist in the environment for long periods. Furthermore, the overuse or improper use of antibiotics may contribute to...
Biological agents used in biological warfare or bioterrorism are also present in bioaerosols. Prompt identification of a biological weapon and its characteristics is necessary. Herein, we optimized an environmentally adaptive detection algorithm that...
Previous studies have consistently revealed that both local and systemic inflammations are the key to the onset and progression of osteoarthritis (OA). Thus, anti-inflammatory biologic agents could potentially attenuate the progression of OA. We cond...
Mechanical impacts on loose biological objects caused by technological equipment can result in both external and internal damage, compromising the quality, storage life, and reproductive capacity of biological materials. This study addresses the need...
In this study, 20% ethanol elution fraction(PC-20), 40% ethanol elution fraction(PC-40), 60% ethanol elution fraction(PC-60), and 80% ethanol elution fraction (PC-80)of Penthorum chinense polyphenols were obtained using AB-8 macroporous resin . Their...
Background: The treatment guidelines for hidradenitis suppurativa (HS) vary among different countries, and several biologics and small molecule inhibitors have been tested for treating moderate-to-severe HS over the past few years. However, treatment...
Concerns regarding the safety, environmental impacts, and long-term sustainability of pesticide-dependent crop protection have intensified interest in biological control, which suppresses pest populations using natural enemies (predators, parasitoids...
Habitat fragmentation (HF) is an ecological process, which is potentially also one of the main causes of diversity loss. Many studies have debated the best tools to adopt for assessing the effects of HF. The traditional application of biodiversity me...
Potentilla nepalensis Hook is a perennial Himalayan medicinal herb of the Rosaceae family. The present study aimed to evaluate biological activities such as the antioxidant, antibacterial, and anticancer activities of roots and shoots of P. nepalensi...
High-Throughput technologies are producing an increasing volume of data that needs large amounts of data storage, effective data models and efficient, possibly parallel analysis algorithms. Pathway and interactomics data are represented as graphs and...
Bruguiera gymnorhiza (L.) Lam is a mangrove plant that spread in many parts of the world. Though mangrove plant polyphenols have been reported to exhibit many biological activities, little is known about mangrove plant tannins. To explore the applica...
Biological sequence analysis is an essential step toward building a deeper understanding of the underlying functions, structures, and behaviors of the sequences. It can help in identifying the characteristics of the associated organisms, such as viru...
Consumption of drugs of abuse is a scourge of modern world. Abuse, drug addiction and their consequences are one of the major current problems of European society because of the significant repercussions in individual, family, social and economic lev...
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