Special Issue "Coumarins and Coumarin Derivatives: From Chemistry to Drug"
Deadline for manuscript submissions: closed (30 April 2019).
Interests: phytochemistry; natural products; coumarin; chemical synthesis; HPLC, oxyprenylated, plant secondary metabolites identification and quantification; anti-inflammatory and anticancer activity
Interests: natural products; pharmaceutical analysis; pharmaceutical synthesis; medicinal chemistry; tossicology
Special Issues and Collections in MDPI journals
Special Issue in Molecules: Current Trends in the Analysis of Medicinal Plants
Interests: coumarin and coumarine derivatives; chemical characterizations; biological activities; plant secondary metabolites
Plant secondary metabolites have played an important role in human welfare due to their great therapeutic potential. Among them, coumarins and coumarin derivatives have gained popularity because of their health benefits; and structurally, coumarin derivatives resamble vitamin K, an important element involved in the synthesis of a numbers of clotting factors. Coumarins belong to the heterocyclic class of organic compounds, naturally present in a large variety of plant families. Since the discovery of the first coumarin, more than 200 years ago, a huge of number of coumarins and analogues have been either isolated or synthesized. Numerous biological activities, including the antimicrobial, the anti-inflammatory, the anti-cancer and the antioxidant properties have been demostratred. In light of these premises, this Special Issue aims to collect contributions on the potential of coumarins and coumarin derivatives to enhance the positive influence in human welfare. Chemical characterizations of plant extracts together with the evaluation of biological activities (cytotoxicity against microorganisms and human cell lines, antimicrobial, antifungal, antioxidant, anti-inflammatory effects) of the mixture, as well as of the single compounds, are required.
Prof. Genovese Salvatore
Dr. Serena Fiorito
Dr. Vito Alessandro Taddeo
Manuscript Submission Information
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- Coumarin and coumarine derivatives
- chemical characterizations
- biological activities
- plant secondary metabolites