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Plants
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Advanced Research in Plant Analytical Chemistry
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Advanced Research in Plant Analytical Chemistry

A special issue of Plants (ISSN 2223-7747). This special issue belongs to the section "Phytochemistry".

Deadline for manuscript submissions: 30 September 2025 | Viewed by 898

Special Issue Editors

Dr. Petar Ristivojevic

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Guest Editor
Department of Analytical Chemistry, Faculty of Chemistry, University of Belgrade, Belgrade, Serbia
Interests: green analytical chemistry; food and forensic methods development; natural product research; planar chromatography
Prof. Dr. Jelena Trifković

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Guest Editor
Department of Analytical Chemistry, Faculty of Chemistry, University of Belgrade, Belgrade, Serbia
Interests: extraction techniques; liquid chromatography; chemometrics; food analysis
Dr. Filip Andrić

E-Mail Website
Guest Editor
Department of Analytical Chemistry, Faculty of Chemistry, University of Belgrade, Belgrade, Serbia
Interests: chemometrics; analytical chemistry; separation methods

Special Issue Information

Dear Colleagues,

The continuous development of advanced analytical techniques has enabled researchers to unlock the intricate chemical profiles of plants, providing critical insights into their chemical composition, biological properties, and potential applications. Plants are an unlimited source of bioactive compounds. This Special Issue, “Advanced Research in Plant Analytical Chemistry”, invites contributions that explore the application of cutting-edge analytical methods in plant research, fostering innovation and advanced knowledge in this multidisciplinary field. Topics of interest include, but are not limited to, research employing novel electrochemical, chromatographic, spectroscopic, and mass spectrometric analytical approaches; integrative techniques like chemometrics, metabolomics, and in silico modeling for the identification and characterization of plant metabolites; the discovery of phytochemicals with health-promoting properties; and the standardization of plant-based products for industrial and commercial applications. The scope of this Special Issue includes addressing critical challenges such as food safety, developing plant-derived pharmaceuticals and cosmetics, and performing forensic investigations involving plant-based substances.

This Special Issue aims for researchers to share their findings, present innovative methodologies, and discuss the transformative role of plant analytical chemistry in driving progress across multiple scientific and industrial disciplines.

Dr. Petar Ristivojevic
Prof. Dr. Jelena Trifković
Dr. Filip Andrić
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Plants is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2700 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • plant metabolites
  • advanced analytical methods
  • phytochemical profiling
  • metabolomics
  • food
  • pharmaceutical and forensic application

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Further information on MDPI's Special Issue policies can be found here.

Published Papers (2 papers)

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19 pages, 1721 KiB  
Article
Bioassay-Guided Isolation of cis-Clerodane Diterpenoids and Monoglycerides from the Leaves of Solidago gigantea and Their Antimicrobial Activities
by Márton Baglyas, Péter G. Ott, Zoltán Bozsó, Ildikó Schwarczinger, József Bakonyi, Dénes Dlauchy, András Darcsi, Szilárd Varga and Ágnes M. Móricz
Plants 2025, 14(14), 2152; https://doi.org/10.3390/plants14142152 - 11 Jul 2025
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Abstract
A previously undescribed cis-clerodane diterpenoid, diangelate solidagoic acid J (1), along with two known cis-clerodane diterpenoids, solidagoic acid C (2) and solidagoic acid D (3), as well as two known unsaturated monoacylglycerols, 1-linoleoyl glycerol ( [...] Read more.
A previously undescribed cis-clerodane diterpenoid, diangelate solidagoic acid J (1), along with two known cis-clerodane diterpenoids, solidagoic acid C (2) and solidagoic acid D (3), as well as two known unsaturated monoacylglycerols, 1-linoleoyl glycerol (4) and 1-α-linolenoyl glycerol (5), were isolated and characterized from the n-hexane leaf extract of Solidago gigantea (giant goldenrod). Compounds 2–5 were identified first in this species, and compounds 4 and 5 are reported here for the first time in the Solidago genus. The bioassay-guided isolation procedure included thin-layer chromatography (TLC) coupled with a Bacillus subtilis antibacterial assay, preparative flash column chromatography, and TLC–mass spectrometry (MS). Their structures were elucidated via extensive spectroscopic and spectrometric techniques such as one- and two-dimensional nuclear magnetic resonance (NMR) spectroscopy and high-resolution tandem mass spectrometry (HRMS/MS). The antimicrobial activities of the isolated compounds were evaluated by a microdilution assay. All compounds exhibited weak to moderate antibacterial activity against the Gram-positive plant pathogen Clavibacter michiganensis, with MIC values ranging from 17 to 133 µg/mL, with compound 5 being the most potent. Only compound 1 was active against Curtobacterium flaccumfaciens pv. flaccumfaciens, while compound 3 demonstrated a weak antibacterial effect against B. subtilis and Rhodococcus fascians. Additionally, the growth of B. subtilis and R. fascians was moderately inhibited by compounds 1 and 5, respectively. None of the tested compounds showed antibacterial activity against Gram-negative Pseudomonas syringae pv. tomato and Xanthomonas arboricola pv. pruni. No bactericidal activity was observed against the tested microorganisms. Compounds 2 and 3 displayed weak antifungal activity against the crop pathogens Bipolaris sorokiniana and Fusarium graminearum. Our results demonstrate the efficacy of bioassay-guided strategies in facilitating the discovery of novel bioactive compounds. Full article
(This article belongs to the Special Issue Advanced Research in Plant Analytical Chemistry)
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18 pages, 5858 KiB  
Article
Analytical Characterization and Pharmacokinetic Insight of Bioactive Compounds from Champia parvula and Moringa oleifera for Biocontrol of Blue Mold in Apple Fruits
by Eman A. Alwaleed, Mashail N. Alzain, Naglaa Loutfy and Amany A. El-Shahir
Plants 2025, 14(14), 2104; https://doi.org/10.3390/plants14142104 - 8 Jul 2025
Viewed by 310
Abstract
The present study aimed to identify the active chemical compounds, mainly phenolic acids, of Champia parvula and Moringa oleifera, evaluate the pharmacokinetic properties of their primary compounds, and assess a novel method for the biocontrol of blue mold by evaluating the antifungal [...] Read more.
The present study aimed to identify the active chemical compounds, mainly phenolic acids, of Champia parvula and Moringa oleifera, evaluate the pharmacokinetic properties of their primary compounds, and assess a novel method for the biocontrol of blue mold by evaluating the antifungal activity of both extracts. Gas chromatography (GC) and high-performance liquid chromatography (HPLC) were utilized to identify the active chemical compounds, mainly phenolic acids. GC illustrated the presence of long-chain aliphatic fatty acids like eicosanoic acid with the formation of oct-1-en-3-ol compounds attached. Catechin was the main bioactive component among the several bioactive compounds identified by HPLC analysis, exhibiting favorable pharmacokinetic behavior, including good absorption, distribution, and metabolic stability. According to the findings, both extracts had antifungal activity, but C. parvula extract (100 mg/mL) exhibited the strongest in vitro and in vivo antifungal activity, with the highest percentages of inhibition (disk diffusion method) against Penicillium expansum, Penicillium crustosum, and Talaromyces atroroseus, ranging between 62.67 and 100%. C. parvula extract (100 mg/mL) could fully inhibit the pathogenicity and aggressiveness of the five tested strains in apple fruits (in vivo). In conclusion, the extract from C. parvula and M. oleifera shows potential antifungal properties and a high phytochemical content. Full article
(This article belongs to the Special Issue Advanced Research in Plant Analytical Chemistry)
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