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Open AccessReview

A Review of the Preparation, Analysis and Biological Functions of Chitooligosaccharide

1
Beijing Key Laboratory of Bioactive Substances and Functional Foods, Beijing Union University, Beijing 100191, China
2
Department of Food Sciences, College of Biochemical Engineering, Beijing Union University, Beijing 100023, China
*
Author to whom correspondence should be addressed.
Int. J. Mol. Sci. 2018, 19(8), 2197; https://doi.org/10.3390/ijms19082197
Received: 13 June 2018 / Revised: 23 July 2018 / Accepted: 25 July 2018 / Published: 27 July 2018
(This article belongs to the Special Issue Chitins 2018)
Chitooligosaccharide (COS), which is acknowledged for possessing multiple functions, is a kind of low-molecular-weight polymer prepared by degrading chitosan via enzymatic, chemical methods, etc. COS has comprehensive applications in various fields including food, agriculture, pharmacy, clinical therapy, and environmental industries. Besides having excellent properties such as biodegradability, biocompatibility, adsorptive abilities and non-toxicity like chitin and chitosan, COS has better solubility. In addition, COS has strong biological functions including anti-inflammatory, antitumor, immunomodulatory, neuroprotective effects, etc. The present paper has summarized the preparation methods, analytical techniques and biological functions to provide an overall understanding of the application of COS. View Full-Text
Keywords: chitin; chitosan; chitooligosaccharide (COS); COS preparation; COS analysis; COS biological activity chitin; chitosan; chitooligosaccharide (COS); COS preparation; COS analysis; COS biological activity
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Liang, S.; Sun, Y.; Dai, X. A Review of the Preparation, Analysis and Biological Functions of Chitooligosaccharide. Int. J. Mol. Sci. 2018, 19, 2197.

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