Detection of BRAFV600E is useful for making diagnosis and risk stratification of papillary thyroid carcinoma (PTC). Molecular testing, however, is not always available for routine clinical use. To assess the clinical utility and reliability of VE1 im...
Background and Objectives: BRAF p.V600E status has diagnostic, prognostic, and therapeutic relevance in colorectal carcinoma. Molecular assays remain the reference methods, whereas mutation-specific BRAF (VE1 clone) immunohistochemistry offers a rapi...
The article investigated the effects of solution and ging temperatures on microstructure and mechanical properties of ultra-high strength stainless steel 10Cr13Co13Mo5Ni3W1VE(S280). Higher solution temperatures can improve impact toughness because of...
During metastasis, cancer cells that originate from the primary tumor circulate in the bloodstream, extravasate, and form micrometastases at distant locations. Several lines of evidence suggest that specific interactions between cancer cells and endo...
5 September 2023
The eVe lidar is a scanning system that can perform combined linear/circular polarization and Raman measurements at 355 nm and consists of the European Space Agency’s (ESA) reference aerosol lidar system. eVe was deployed in the ASKOS campaign,...
Hydraulic fracturing operations target enhancing the productivity of tight formations through viscous fluid injection to break down the formation and transport proppant. Crosslinked polymers are usually used for desired viscoelasticity of the fractur...
The Vietnamese economy has increased at high speed over the transformation decades; however, most recent studies on the economic growth of this country used the Cobb-Douglas or CES (Constant Elasticity of Substitution) production functions, which are...
VE-cadherin (VE-cad) membrane stability and localization regulates adhesion formation and actin cytoskeleton dynamics in angiogenesis and vascular remodeling and requires the heparan sulfate proteoglycan (HSPG), Syndecan-4 (Sdc4). This study characte...
In hydraulic fracturing, fracturing fluids are used to create fractures in a hydrocarbon reservoir throughout transported proppant into the fractures. The application of many fields proves that conventional fracturing fluid has the disadvantages of r...
Long COVID-19 syndrome appears after Severe Acute Respiratory Syndrome-Corona Virus (SARS-CoV-2) infection with acute damage to microcapillaries, microthrombi, and endothelialitis. However, the mechanisms involved in these processes remain to be eluc...
To overcome the resistance to radiotherapy in chondrosarcomas, the prevention of efficient DNA repair with an additional treatment was explored for particle beams as well as reference X-ray irradiation. The combined treatment with DNA repair inhibito...
The clinical success of neutralizing vascular endothelial growth factor (VEGF) has unequivocally identified VEGF as a driver of retinal edema that underlies a variety of blinding conditions. VEGF is not the only input that is received and integrated...
Vascular endothelial cadherin (VE-Cadherin) is a major endothelial adhesion molecule and can be cleaved explicitly by metalloproteinase domain-containing protein 10 (ADAM10). Vascular hyperpermeability may contribute to a greater susceptibility to se...
The mesenchymal subtype of glioblastoma (mGBM), which is characterized by rigorous vasculature, resists anti-tumor immune therapy. Here, we investigated the mechanistic link between tumor vascularization and the evasion of immune surveillance. Clinic...
Cardiopulmonary exercise testing (CPET) was limited to peak oxygen consumption analysis (VO2peak), and now the ventilation/carbon dioxide production (VE/VCO2) slope is recognized as having independent prognostic value. Unlike VO2peak, the VE/VCO2 slo...
Monascus spp. is widely used in food fermentation and additive production, and some of its strains produce citrinin (CIT), which is nephrotoxic. In this study, we constructed a mutant strain of Monascus ruber M7 (M. ruber M7) with a VeA gene deletion...
Bulk 2D electronic–vibrational (2D-EV) and 2D vibrational–electronic spectroscopies (2D-VE) were previously developed to correlate the electronic and vibrational degrees of freedom simultaneously, which allow for the study of couplings be...
Hydrocephalus induced by intraventricular hemorrhage (IVH) is associated with unfavorable prognosis. The increased permeability of choroid plexus and breakdown of the blood–brain barrier (BBB) was reported as a prominent mechanism of IVH-induce...
Virtualized infrastructure management has shifted from traditional reactive monitoring to proactive observability. However, the literature regarding Proxmox Virtual Environment (VE) monitoring using custom agents remains fragmented. This study presen...
Sensitization to cross-reactive allergens complicates identifying the culprit insect in Hymenoptera venom allergy via diagnostic tests. This study evaluates sensitization to hyaluronidases (Api m 2 from honey bee (Apis mellifera) venom, HBV; Pol d 2...
We investigated the performance of viscoelastic surfactant (VES) solution when applied in treatment on the uninvaded matrix using core flooding tests to analyze the impact of VES/CaCl2 concentration on fluid viscosity. In this paper, core samples fro...
DNA damaging agents such as ionizing radiation or chemotherapy are frequently used in oncology. DNA damage response (DDR)—triggered by radiation-induced double strand breaks—is orchestrated mainly by three Phosphatidylinositol 3-kinase-related kinase...
Lymphatic metastasis is a biological procedure associated with the pathogenesis of several diseases, especially in tumor metastasis. Therefore, regulation of lymphangiogenesis has become a promising strategy for cancer therapy. In this study, we aime...
Ensuring secure and reliable communication in Vehicular Ad hoc Networks (VANETs) is critical for safe transportation systems. This paper presents Vehicular Misbehavior Network (VeMisNet), a deep learning framework for detecting misbehaving vehicles,...
Background: The erythrocyte sedimentation rate (ESR) is a routine and aspecific test that is still widely used. The reference-manual method for ESR determination is the Westergren method. The VES-MATIC 5 is a novel, fully automated, and closed system...
In the context of the increasingly severe energy crisis and global warming, green buildings and their energy-saving issues are being paid more attention in the world. Since envelope optimization can significantly reduce the energy consumption of gree...
This study used all-atom molecular dynamics simulations to investigate the structural dynamics of Ves a 1, a phospholipase from Vespa affinis venom, and its interactions within a lipid membrane environment, both alone and in the presence of the inhib...
Cultural ecosystem services (CES) play a vital role in rural well-being, yet their spatial patterns and local perceptions remain underexplored in many regions, including Türkiye. This study aims to assess the social values of CES in rural landsc...
The goal of our study was to investigate the impact of p-cresylsulfate (PCS) on the barrier integrity in human umbilical vein endothelial cell (HUVEC) monolayers and the renal artery of chronic kidney disease (CKD) patients. We measured changes in th...
In the process of the operation and maintenance of secondary devices in smart substation, a wealth of defect texts containing the state information of the equipment is generated. Aiming to overcome the low efficiency and low accuracy problems of arti...
Fusarium proliferatum is the causative agent of rice spikelet rot disease, which can produce a group of toxic secondary metabolites, especially fumonisins. Velvet complex is a master regulator governing the development processes and secondary metabol...
In the pragmaticalization of ya ves que… ‘you see that…’, the perceptual basis of the verb becomes diluted, keeping its deictic profile. Most of its pragmatic values extend to non-perceptual phenomena, implying shared knowle...
Tumor growth depends on the vascular system, either through the expansion of blood vessels or novel adaptation by tumor cells. One of these novel pathways is vasculogenic mimicry (VM), which is defined as a tumor-provided vascular system apart from e...
Velvet (VeA), a light-regulated protein that shuttles between the cytoplasm and the nucleus, serves as a key global regulator of secondary metabolism in various Aspergillus species and plays a pivotal role in controlling multiple developmental proces...
The airborne AirSWOT instrument suite, consisting of an interferometric Ka-band synthetic aperture radar and color-infrared (CIR) camera, was deployed to northern North America in July and August 2017 as part of the NASA Arctic-Boreal Vulnerability E...
Vasculogenic mimicry (VM) is the alternative process of forming vessel-like networks by aggressive tumor cells, and it has an important role in tumor survival, growth, and metastasis. Epigallocatechin-3-gallate (EGCG) is well known to have diverse bi...
Assessing social values attributed to ecosystem services based on the Social Values for Ecosystem Services (SolVES) model helps ecosystems to provide services sustainably, including land and forest products and non-material services. Currently, urban...
In the last decade, the soil borne fungal pathogen Verticillium dahliae has had an increasingly strong effect on fiber flax (Linum usitatissimum L.), thus causing important yield losses in Normandy, France. Race-specific resistance against V. dahliae...
Points-of-interest (POIs) are an important carriers of location text information in smart cities and have been widely used to extract and identify urban functional regions. However, it is difficult to model the relationship between POIs and urban fun...
The endothelial cells (EC) of established blood vessels in adults remain extraordinarily quiescent in the sense that they are not actively proliferating, but they fulfill the necessary role to control the permeability of their monolayer that lines th...
Internet technologies are emerging very fast nowadays, due to which web pages are generated exponentially. Web page categorization is required for searching and exploring relevant web pages based on users’ queries and is a tedious task. The majority...
The Gompertz growth curve is used to describe the urban water population, the linear function is used to represent the per capita disposable income, and the domestic water demand is described combined with the factors of population, income, and the w...
Mounting evidence supports the role of the endocannabinoid system in neurophysiology, including blood–brain barrier (BBB) function. Recent work has demonstrated that activation of endocannabinoid receptors can mitigate insults to the BBB during...
The objective of this study was to investigate the molecular response to damage at the blood-brain barrier (BBB) and to elucidate critical pathways that might lead to effective treatment in central nervous system (CNS) pathologies in which the BBB is...
Increasing load requirements and harsh operating conditions have worsened the wear of drive shafts in special field vehicles. In this paper, the evolution of the microstructure and fretting wear behaviors of 25CrNi2MoVE torsion shaft steel and their...
Viscoelastic surfactants (VES) are amphiphilic molecules which self-assemble into long polymer-like aggregates—wormlike micelles. Such micellar chains form an entangled network, imparting high viscosity and viscoelasticity to aqueous solutions....
The access road to the powerhouse’s hydraulic system’s facilities in Guarumales (Azuay, Ecuador) presents a medium-sized landslide. Geophysical tests were conducted in the initial research stage, combining electrical and seismic methods....
As cities continue to grow, the functions of urban areas change and problems arise from previously constructed urban planning schemes. Hence, the actual distribution of urban functional areas needs to be confirmed. POI data, as a representation of ur...
The process of full-thickness skin regeneration is complex and has many parameters involved, which makes it difficult to use a single dressing to meet the various requirements of the complete regeneration at the same time. Therefore, developing hydro...
Impairment of vascular endothelial integrity is associated with various vascular diseases. Our previous studies demonstrated that andrographolide is critical to maintaining gastric vascular homeostasis, as well as to regulating pathological vascular...
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