Addition of bioactive materials such as calcium phosphates or Bioglass, and incorporation of porosity into polyetheretherketone (PEEK) has been identified as an effective approach to improve bone-implant interfaces and osseointegration of PEEK-based...
In this paper, Ti-27Nb-17Ta-8Zr/HA series composite materials were prepared by spark plasma sintering (SPS) technology. The medical titanium alloy (Ti-27Nb-17Ta-8Zr) with good mechanical properties, wear resistance, and corrosion resistance was combi...
Bone morphogenetic protein-2 (BMP-2) is used in the treatment of degenerative spinal disease and vertebral fractures, spine fusion, dental surgery, and facial surgery. However, high doses are associated with side effects such as inflammation and oste...
(1) Background: Avian influenza viruses (AIVs) promptly evade preexisting immunity by constantly altering the immunodominant neutralizing antibody epitopes (antigenic drift) or by procuring new envelope serotypes (antigenic shift). As a consequence,...
Many modern rabbis insist that original sin was invented by St. Paul, and that it does not have a Jewish antecedent. Instead, rabbinic Judaism explains human evil in terms of “yeṣer ha-raʻ,” “the evil inclination.”...
The incorporation of bioactive ceramic into polyether ether ketone (PEEK) was expected to improve the bioinertia and hydrophobicity of pure PEEK, further facilitating osseointegration and bone ingrowth. However, the addition of bioceramic also change...
To improve the performance of porous hydroxyapatite/titanium (HA/Ti) composites, LaF3 reinforced porous HA/Ti scaffolds with a porosity of approximately 60% were prepared via a powder metallurgical method, using NH4HCO3 as the pore-forming agent. The...
Increased hyaluronic acid (HA) production is often associated with cancer progression. In malignant pleural mesothelioma (MPM), HA is found at elevated levels in pleural effusions and sera of patients, and it has been widely debated whether MPM cells...
Background: Botulinum neurotoxins (BoNTs) comprise seven agreed-on serotypes, A through G. In 2014, a novel chimeric neurotoxin produced by clostridial strain IBCA10-7060 was reported as BoNT/H, with subsequent names of BoNT/FA or BoNT/HA based on se...
Microbial adhesion is critical for parasitic infection and colonization of host cells. To study the host–parasite interaction in vitro, we established a flow cytometry-based assay to measure the adherence of Trichomonas vaginalis to epithelial...
Many cases of human infection with the H7N9 virus have been detected in China since 2013. H7N9 viruses are maintained in chickens and are transmitted to humans at live bird markets. During circulation in birds, H7N9 viruses have accumulated amino aci...
In this study, niobium/zirconium dioxide/hydroxyapatite (Nb/ZrO2/HA) composite coating was deposited on ZK60 magnesium alloy by the plasma spraying technique. The effects of spraying power and the powder feeding rate on the surface morphology, corros...
Fe/Mn (hydr)oxides are metallic compounds that exhibit significant redox activity in environmental media and play a pivotal role in geochemical processes, thereby influencing the fate of metals in porous media. The morphology of Fe/Mn (hydr)oxides in...
In modern surgery, the internal fixation plates fabricated from hydroxyapatite/poly(L-lactide) (HA/PLLA) composites encounter clinical limitations in fracture treatment due to their inadequate mechanical properties. In this work, pressure-induced flo...
In the present work, the fabrication of a membrane composed of polylactic acid (PLA), polyvinyl alcohol (PVA), and Biological Hydroxyapatite (BIO-HA) is reported using the coaxial electrospinning technique. The membrane fabrication process involved m...
Biodegradability is one of the most important properties of implantable bone biomaterials, which is directly related to material bioactivity and the osteogenic effect. How foreign body giant cells (FBGC) involved in the biodegradation of bone biomate...
Aesthetic medicine has progressed from the early 2000s fascination with bio-stimulation to the current dominance of hyaluronic acid (HA) fillers, prized for immediate, predictable, and reversible volumizing effects. Recently, demand for more natural...
Binding of cell surface glycoprotein CD44 to hyaluronic acid (HA) is a key event for mediating cell adhesion, motility, metastasis, inflammatory responses and tumor development, but the regulation mechanism and its molecular basis under diverse mecha...
Laser post-heating computer controlled detonation spraying (CCDS) and cold spray (CS) hybrid processes were proposed for fabrication of near sub micron structure coatings of hydroxyapatite (HA) + Ti system. Optical and SEM with energy dispersive X-ra...
In this paper, a novel nanocrystalline composite material of hydroxyapatite (HA)/polyvinyltrimethoxysilane (PVTMS)/iron(II)chloride tetrahydrate (Cl2FeH8-O4) with hexagonal structure is proposed for the fabrication of a gas/temperature sensor. Taking...
A significant share of allogeneic hematopoietic stem cell transplantations (allo-HSCT) results in the relapse of malignant disease. The T cell immune response to minor histocompatibility antigens (MiHAs) promotes a favorable graft-versus-leukemia res...
Influenza virus infections pre-dispose an individual to secondary pneumococcal infections, which represent a serious public health concern. Matching influenza vaccination was demonstrated helpful in preventing postinfluenza bacterial infections and a...
This comparative study investigated the tissue regeneration and inflammatory response induced by xenografts comprised of hydroxyapatite (HA) and demineralized bone matrix (DBM) extracted from porcine (P) and bovine (B) sources. First, extraction of H...
As the major form of urbanization, urban agglomeration integrates urban resources, adjusts industrial structure, narrows the gap between urban and rural areas, enhances urban function, strengthens urban competitiveness, and promotes the strategy of r...
Nanometer hydroxyapatite (n-HA) powders were synthesized by the chemical precipitation method, and a novel ZnO/HA composite, which consisted of second-phase particles with different sizes and distributions, was successfully fabricated. ZnO/HA composi...
Novel H7N9 influenza virus transmitted from birds to human and, since March 2013, it has caused five epidemic waves in China. Although the evolution of H7N9 viruses has been investigated, the evolutionary changes associated with codon usage are still...
Apigenin (API) possesses excellent antitumor properties but its limited water solubility and low bioavailability restrict its therapeutic impact. Thus, a suitable delivery system is needed to overcome these limitations and improve the therapeutic eff...
An alloy surface with possible applications in the medical field, Ti4A14Zr, was improved through the deposition of a thin hydroxyapatite (HA) layer. In this paper, we analyzed the growth of a HA layer through electrophoresis and the corrosion resista...
In this study, new composites based on polyvinylidene fluoride (PVDF) were ornamented and prepared with hydroxyapatite (HA) and silver nitride (AgNO3). Taking into account the polarity of the solvent dimethyl sulfoxide, this solvent was used to dispe...
Background/Objectives: The H7N9 avian influenza virus (AIV) constitutes a novel subtype of influenza virus that has emerged within the past decade. Empirical studies have demonstrated that H7N9 AIV holds the potential to trigger a human pandemic. Vac...
Scaffolds based on aligned and non-aligned poly (L-lactic acid) (PLLA)/polycaprolactone (PCL) fibers obtained by electrospinning, associated to electrosprayed hydroxyapatite (HA) for tissue engineering applications were developed and their performanc...
At present, the magnetic selection of genetically modified cells is mainly performed with surface markers naturally expressed by cells such as CD4, LNGFR (low affinity nerve growth factor receptor), and MHC class I molecule H-2Kk. The disadvantage of...
Ha-Soo-Oh is a traditional Chinese medicine prepared from the roots of Polygonum multiflorum Thunb. The herb extract has been widely used in Asian countries as a tonic agent and nutritional supplement for centuries. To identify new bioactive compound...
The successful regeneration of large-size bone defects remains one of the most critical challenges faced in orthopaedics. Recently, 3D printing technology has been widely used to fabricate reliable, reproducible and economically affordable scaffolds...
The present work reports on the microstructural and micro-mechanical characterization of Ti-Nb-HA-based composites. The composites were prepared via a spark plasma sintering (SPS) consolidation process. The effect of two distinct levels of hydroxyapa...
Climate change is projected to bring substantial changes to hydroclimatic extremes, which will affect natural river regimes and have wide-ranging impacts on human health and ecosystems, particularly in Central Highland Vietnam. This study focuses on...
Magnesium alloy ZK60 shows great promise as a medical metal material, but its corrosion resistance in the body is inadequate. Hydroxyapatite (HA), the primary inorganic component of human and animal bones, can form chemical bonds with body tissues at...
We demonstrate that Ha-RasV12 overexpression induces the nuclear translocation of Hippo effector Yes-associated protein (YAP) in MDCK cells via the hippo-independent pathway at the confluent stage. Ha-RasV12 overexpression leads to the downregulation...
To reduce the possibility of bacterial infection and implant-related complications, surface modification on polyurethane (PU) film is an ideal solution to endow hydrophobic PU with antibacterial and antifouling properties. In this work, a variety of...
21 November 2019
After tooth extraction, alveolar ridge loss due to resorption is almost inevitable. Most of this bone loss occurs during the first six months after the extraction procedure. Many studies have indicated that applying socket-filling biomaterials after...
Background: Influenza remains a persistent public health challenge due to antigenic drift and shift, necessitating vaccines capable of eliciting broad and durable immunity. Hemagglutinin (HA) antigen serves as the critical target for eliciting protec...
Atopic dermatitis (AD) is a skin allergy accompanied by acute and chronic dermal inflammation. In traditional oriental medicine, Laminaria japonica has been used to treat various diseases, including inflammatory diseases. Therefore, to determine the...
The use of non-standard culture conditions has proven efficient to increase cell performance and recombinant protein production in different cell hosts. However, the establishment of high-producing cell populations through adaptive laboratory evoluti...
This study proposes the use of spatial high-resolution Formosat-5 (FS5) images for estimating total suspended matter (TSM) concentrations in a coastal region. Although many atmospheric correction methods are available, none of them are proposed to ap...
The recent emergence of a new myxoma virus capable of causing disease in the Iberian hare (Lepus granatensis) has resulted in numerous outbreaks with high mortality leading to the reduction, or even the disappearance, of many local populations of thi...
Metal chelators are used for various industrial and medical purposes based on their physicochemical properties and biological activities. In biological systems, copper ions bind to certain enzymes as cofactors to confer catalytic activity or bind to...
To explore the corrosion of Q235 steel in sand containing a simulated haze aqueous solution (HA solution) under a natural air-dried state, the effect of moisture (age) on the corrosion of Q235 steel in sand was comprehensively studied by EIS, polariz...
The introduction of Shakespeare to China was through the Chinese translation of Mary and Charles Lamb’s adaptation of Shakespeare’s plays, Tales from Shakespeare. The Western missionaries’ Chinese translations of the Lambs’ ad...
Metallic biomaterials in a solid form cause stress-shielding in orthopedic applications. Such implants also suffer from limited tissue attachment to become a part of the living system. In view of that, hydroxyapatite (HA) coating reinforced with tita...
H9N2 avian influenza virus (AIV) has become endemic in many countries, causing great economic losses when co-infected with other pathogens. So far, several live vaccines based on Newcastle disease virus (NDV) vectors expressing influenza hemagglutini...
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