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5,044 Results Found

  • Article
  • Open Access
1 Citations
2,336 Views
14 Pages

15 May 2024

In this paper, a novel data transmission scheme, interference perceptual multi-modulation (IP-MM), is proposed for full-duplex (FD) systems. In order to unlink the conventional uplink (UL) data transmission using a single modulation and coding scheme...

(This article belongs to the Topic Application of Deep Learning Method in 6G Communication Technology)
  • Review
  • Open Access
2 Citations
979 Views
64 Pages

Nutrient-Driven Modulation of Microbial, Plant, and Rhizosphere Processes for Heavy Metal Remediation

  • Lixia Wang,
  • Xiaoping Zang,
  • Hafiz Faiq Bakhat,
  • Ghulam Abbas Shah and ,
  • Tao Jing,
  • Yan Zhao and
  • Yingdui He
  • + 2 authors+ 0 author

15 May 2026

Heavy metal pollution remains a major global environmental challenge due to persistent ecological risks and potential threats to food safety. Microbial remediation and phytoremediation represent sustainable alternatives to conventional treatments; ho...

(This article belongs to the Special Issue Heavy Metal Toxicity in Plants and Phytoremediation)
  • Article
  • Open Access
374 Views
17 Pages

Baicalein Attenuates Disuse-Driven Skeletal Senescence in Association with Gut Microbiota Modulation

  • Xin Zhao,
  • Tingting Ren,
  • Wei Bai,
  • Hong Wang and ,
  • Siddiq Ur Rahman,
  • Xiaoni Deng,
  • Kang Ru,
  • Genyang Zhang,
  • Wenjuan Zhang and
  • Airong Qian
  • + 5 authors+ 0 author

20 September 2026

The progression of skeletal senescence under mechanical unloading conditions elevates fracture risk, emerging as a critical health challenge for the general population and astronauts during spaceflight. Nevertheless, current therapeutic strategies de...

(This article belongs to the Special Issue Natural Bioactive Compounds: Therapeutic Potential in the Management of Chronic Diseases)
  • Article
  • Open Access
5 Citations
3,151 Views
15 Pages

A Convolutional Dynamic-Jerk-Planning Algorithm for Impedance Control of Variable-Stiffness Cable-Driven Manipulators

  • Luyang Zhang,
  • Lihui Jia,
  • Panpan Yang,
  • Zixuan Li and ,
  • Yuhuan Zhang,
  • Xiang Cheng and
  • Zonggao Mu
  • + 2 authors+ 0 author

19 November 2022

Cable-driven manipulators, characterized by slender arms, dexterous motion, and controllable stiffness, have great prospects for application to capture on-orbit satellites. However, it is difficult to achieve effective motion planning and stiffness c...

(This article belongs to the Special Issue Micro/Nano Resonators, Actuators, and Their Applications)
  • Article
  • Open Access
3 Citations
2,469 Views
22 Pages

Research on a Data-Driven Modeling Method for Precast Concrete Balcony Components

  • Jie Cai,
  • Xin Wang,
  • Junfeng Shi,
  • Xingxing Xie and ,
  • Yu Feng and
  • Yingjun Wu
  • + 1 author+ 0 author

29 December 2023

In this paper, a data-driven modeling method for precast concrete (PC) balcony components was proposed to solve the problems of low informatization and the difficult modeling of components at the design stage. Through the analysis of the characterist...

(This article belongs to the Special Issue Advanced Technologies for Urban and Architectural Design)
  • Article
  • Open Access
1 Citations
3,184 Views
18 Pages

15 March 2025

This study presents a novel dual phase-locked loop two-dimensional synchronized motion modulation (TDSMM-DPLL) system designed to enhance the low-frequency detection capability of magnetoresistive (MR) sensors by effectively mitigating 1/f noise. The...

(This article belongs to the Section Electronic Sensors)
  • Article
  • Open Access
28 Citations
8,041 Views
16 Pages

Performance Evaluation of an Autonomously Driven Agricultural Vehicle in an Orchard Environment

  • Joong-hee Han,
  • Chi-ho Park,
  • Young Yoon Jang,
  • Ja Duck Gu and
  • Chan Young Kim

24 December 2021

To address the problems of inefficient agricultural production and labor shortages, there has been active research to develop autonomously driven agricultural machines, using advanced sensors and ICT technology. Autonomously driven speed sprayers can...

(This article belongs to the Special Issue Robotics and Sensors Technology in Agriculture)
  • Article
  • Open Access
614 Views
17 Pages

Resolving inverse kinematics and evaluating constrained workspace remain challenging for multi-module cable-driven robots. This paper analyzes a dual-module cable-driven hybrid robot inspired by inchworm locomotion and proposes a new configuration-ba...

(This article belongs to the Section Robotics, Mechatronics and Intelligent Machines)
  • Article
  • Open Access
1,519 Views
6 Pages

Analysis of field-stressed modules from a fuel-cell vehicle’s main inverter

  • Hye-Seong Heo,
  • Christoph Pannemann,
  • Yun-Kyu Choi,
  • Carlos Castro and
  • Achim Strass

This paper presents a reliability study of a directly cooled and an indirectly cooled IGBT module after a test drive of 85.000 Km in a fuel cell electric vehicle. In this case, the car was mainly driven on highway, only a minor part of the distance w...

  • Article
  • Open Access
14 Citations
4,810 Views
9 Pages

Optimization of Electron Beams Based on Plasma-Density Modulation in a Laser-Driven Wakefield Accelerator

  • Lintong Ke,
  • Changhai Yu,
  • Ke Feng,
  • Zhiyong Qin and ,
  • Kangnan Jiang,
  • Hao Wang,
  • Shixia Luan,
  • Xiaojun Yang,
  • Yi Xu and
  • Ruxin Li
  • + 8 authors+ 3 authors

12 March 2021

We demonstrate a simple but efficient way to optimize and improve the properties of laser-wakefield-accelerated electron beams (e beams) based on a controllable shock-induced density down-ramp injection that is achieved with an inserted tunable shock...

  • Article
  • Open Access
8 Citations
5,666 Views
19 Pages

A G316A Polymorphism in the Ornithine Decarboxylase Gene Promoter Modulates MYCN-Driven Childhood Neuroblastoma

  • Laura D. Gamble,
  • Stefania Purgato,
  • Michelle J. Henderson,
  • Simone Di Giacomo and ,
  • Amanda J. Russell,
  • Paolo Pigini,
  • Jayne Murray,
  • Emanuele Valli,
  • Giorgio Milazzo and
  • Michelle Haber
  • + 30 authors+ 25 authors

9 April 2021

Ornithine decarboxylase (ODC1), a critical regulatory enzyme in polyamine biosynthesis, is a direct transcriptional target of MYCN, amplification of which is a powerful marker of aggressive neuroblastoma. A single nucleotide polymorphism (SNP), G316A...

(This article belongs to the Section Molecular Cancer Biology)
  • Article
  • Open Access
1 Citations
4,144 Views
11 Pages

Measuring Thermally-Driven LED Emissions via Voltage Modulation near Zero Bias

  • Peter M. Orem,
  • Kyle T. Vogt,
  • Matt W. Graham and
  • Frank M. Orem

28 November 2018

This study was launched to demonstrate that LEDs at zero bias show recombination photon emissions, and to check the models for the same. A method for measuring the light emission for a LED near zero bias is presented. A large reverse bias sufficient...

(This article belongs to the Section Microelectronics)
  • Article
  • Open Access
25 Citations
5,910 Views
22 Pages

24 November 2022

With the development of the underwater acoustic (UWA) adaptive communication system, energy-efficient transmission has become a critical topic in underwater acoustic (UWA) communications. Due to the unique characteristics of the underwater environmen...

(This article belongs to the Special Issue Underwater Communication and Networking)
  • Article
  • Open Access
11 Citations
9,258 Views
20 Pages

Over the last few decades, computer-aided engineering (CAE) tools have been developed and improved in order to ensure a short time-to-market in the chip design business. Up to now, these design tools do not yet support an integrated design strategy f...

  • Review
  • Open Access
27 Citations
5,945 Views
24 Pages

Critical Analysis of Non-Thermal Plasma-Driven Modulation of Immune Cells from Clinical Perspective

  • Barbora Smolková,
  • Adam Frtús,
  • Mariia Uzhytchak,
  • Mariia Lunova and ,
  • Šárka Kubinová,
  • Alexandr Dejneka and
  • Oleg Lunov
  • + 2 authors+ 0 author

28 August 2020

The emerged field of non-thermal plasma (NTP) shows great potential in the alteration of cell redox status, which can be utilized as a promising therapeutic implication. In recent years, the NTP field considerably progresses in the modulation of immu...

(This article belongs to the Section Molecular Biophysics)
  • Article
  • Open Access
2 Citations
1,186 Views
21 Pages

15 December 2025

The reliability of electric vehicle (EV) batteries requires detecting surface defects but also precisely locating them on the physical module for automated inspection, repair, and process optimisation. Conventional 2D computer vision methods, though...

(This article belongs to the Special Issue Convolutional Neural Network Technology for 3D Imaging and Sensing)
  • Article
  • Open Access
37 Citations
4,159 Views
20 Pages

Understanding Salinity-Driven Modulation of Microbial Interactions: Rhizosphere versus Edaphic Microbiome Dynamics

  • Rui Li,
  • Haihua Jiao,
  • Bo Sun,
  • Manjiao Song and ,
  • Gaojun Yan,
  • Zhihui Bai,
  • Jiancheng Wang,
  • Xuliang Zhuang and
  • Qing Hu
  • + 4 authors+ 0 author

Soil salinization poses a global threat to terrestrial ecosystems. Soil microorganisms, crucial for maintaining ecosystem services, are sensitive to changes in soil structure and properties, particularly salinity. In this study, contrasting dynamics...

(This article belongs to the Special Issue Advances in Soil Microbial Ecology)
  • Article
  • Open Access
3 Citations
2,140 Views
21 Pages

Niacin Modulates SIRT1-Driven Signaling to Counteract Radiation-Induced Neurocognitive and Behavioral Impairments

  • Erdinç Tunç,
  • Hatice Aygün,
  • Mümin Alper Erdoğan,
  • Yiğit Uyanıkgil and
  • Oytun Erbaş

Radiation exposure causes neuroinflammation, oxidative stress, and neuronal loss, leading to cognitive and behavioral impairments. This study aims to evaluate the effect of niacin interventions on whole-brain irradiation (WBI)-induced cognitive and b...

(This article belongs to the Section Molecular Toxicology)
  • Article
  • Open Access
1 Citations
1,161 Views
13 Pages

Targeting Inflammation: Cytosporone B Modulates Imatinib-Driven Biochemical Alterations in Rat Heart

  • Denise Börzsei,
  • András Nagy,
  • Viktória Kiss,
  • Zoltán Virág and ,
  • Gyöngyi Kis,
  • Nikoletta Almási,
  • Szilvia Török,
  • Médea Veszelka,
  • Csaba Varga and
  • Renáta Szabó
  • + 5 authors+ 0 author

15 October 2025

In recent decades, chemotherapy has significantly improved cancer survival, yet its adverse effects on non-cancerous tissues raise increasing concerns. In this context, growing attention has been focused on natural compounds that may be useful in mit...

(This article belongs to the Special Issue Molecular Mechanisms and Therapeutic Targets in Cardiovascular Health and Cardiotoxicity)
  • Review
  • Open Access
1 Citations
2,662 Views
25 Pages

21 November 2025

Protein droplets exhibit complex self-assembly and deposition behaviors driven by evaporation, which has attracted increasing attention in recent years. Under evaporation, limited volume and locally concentrated protein solutions can undergo liquid&n...

  • Article
  • Open Access
2 Citations
1,644 Views
22 Pages

Solvent-Driven Structural Modulation of Co-Ni3S2 and Impact on Electrochemical Water Splitting

  • Sagar M. Mane,
  • Komal S. Wagh,
  • Sangoh Lee,
  • Aviraj M. Teli and ,
  • Ganesh T. Chavan,
  • Jae Cheol Shin and
  • Jaewoong Lee
  • + 2 authors+ 0 author

28 October 2025

Understanding the role of synthesis parameters in tailoring catalyst morphology is crucial for enhancing performance in electrochemical water splitting. This research systematically explores how different solvent environments affect the structural ev...

(This article belongs to the Special Issue Featured Papers in Inorganic Materials 2025)
  • Perspective
  • Open Access
7 Citations
5,472 Views
5 Pages

29 September 2025

Aging results from the combined effects of oxidative stress, chronic low-grade inflammation, mitochondrial decline, and cellular senescence, which together drive age-related disorders. Natural products ranging from polyphenols and terpenoids to alkal...

(This article belongs to the Special Issue Research Progress on Anti-Aging with Natural Products)
  • Article
  • Open Access
1 Citations
552 Views
15 Pages

Nutrient Supply Gradients Modulate Cultivation-Driven Restructuring of Microbial Communities in Desert Soils

  • Feng Wen,
  • Xiru Chen,
  • Qiannan Chen,
  • Lianqiang Li and ,
  • Yingying Zhao,
  • Yongxia You,
  • Shihao Niu and
  • Zhanfeng Xia
  • + 3 authors+ 0 author

9 May 2026

Understanding how cultivation conditions influence the recovery of microbial diversity is critical for interpreting cultivation-derived communities in relation to in situ microbial ecology, particularly in nutrient-limited environments such as desert...

  • Article
  • Open Access
3 Citations
4,820 Views
14 Pages

Advanced Laser–Plasma Diagnostics for a Modular High-Repetition-Rate Plasma Electron Accelerator

  • Christian Greb,
  • Esin Aktan,
  • Roman Adam,
  • Alex Dickson and ,
  • Cédric Sire,
  • Viktoria E. Nefedova,
  • François Sylla,
  • Rodrigo Lopez-Martens,
  • Claus M. Schneider and
  • Markus Büscher
  • + 6 authors+ 1 author

We present a laser–plasma electron accelerator module designed to be driven by high-repetition-rate lasers for industrial applications of laser-driven electron beams. It consists of a single vacuum chamber containing all the necessary component...

  • Communication
  • Open Access
91 Citations
10,848 Views
21 Pages

Digital Twin-Driven Human Robot Collaboration Using a Digital Human

  • Tsubasa Maruyama,
  • Toshio Ueshiba,
  • Mitsunori Tada,
  • Haruki Toda and ,
  • Yui Endo,
  • Yukiyasu Domae,
  • Yoshihiro Nakabo,
  • Tatsuro Mori and
  • Kazutsugu Suita
  • + 4 authors+ 0 author

10 December 2021

Advances are being made in applying digital twin (DT) and human–robot collaboration (HRC) to industrial fields for safe, effective, and flexible manufacturing. Using a DT for human modeling and simulation enables ergonomic assessment during wor...

(This article belongs to the Special Issue Digital Twins, Sensing Technologies and Automation in Industry 4.0)
  • Article
  • Open Access
11 Citations
6,803 Views
15 Pages

Development of a Tendon-Driven Continuum Robot for Medical Applications

  • N. Yaswanth Siva Sai,
  • Prajakta Koratkar,
  • Indrajit Desai,
  • Rajkumar Bhimgonda Patil and
  • Sandip Mane

6 February 2025

This paper presents the design, kinematics, and development of a tendon-driven continuum robot for surgical applications. The continuum robot has a flexible and adaptable construction that imitates the movements of natural organisms. The robot’...

(This article belongs to the Section Electrical and Electronic Engineering)
  • Article
  • Open Access
663 Views
11 Pages

5 June 2026

Polymer–liquid crystal (polymer–LC) composites enable electrically tunable optical modulation through the coupling of molecular anisotropy and polymer-induced stabilization. However, most dual-cell LC architectures that independently cont...

(This article belongs to the Section Polymer Applications)
  • Article
  • Open Access
10 Citations
6,453 Views
10 Pages

25 April 2018

The propagation characteristics of high-power laser beams in plasma is an important research topic and has many potential applications in fields such as laser machining, laser-driven accelerators and laser-driven inertial confined fusion. The dynamic...

(This article belongs to the Section Optics and Lasers)
  • Article
  • Open Access
3 Citations
3,055 Views
11 Pages

High-Linear Frequency-Swept Lasers with Data-Driven Control

  • Haohao Zhao,
  • Dachao Xu,
  • Zihan Wu,
  • Liang Sun and ,
  • Guohui Yuan and
  • Zhuoran Wang
  • + 1 author+ 0 author

18 September 2023

The frequency-swept laser (FSL) is applied widely in various sensing systems in the scientific and industrial fields, especially in the light detection and ranging (Lidar) area. However, the inherent nonlinearity limits its performance in application...

  • Article
  • Open Access
3 Citations
2,038 Views
31 Pages

Semantic-Attention Enhanced DSC-Transformer for Lymph Node Ultrasound Classification and Remote Diagnostics

  • Ying Fu,
  • Shi Tan,
  • Michel Kadoch,
  • Jinghua Zhong and ,
  • Lifeng Guo,
  • Yangan Zhang,
  • Xiaohong Huang and
  • Xueguang Yuan
  • + 3 authors+ 0 author

This study presents a novel Semantic-Attention Enhanced Dynamic Swin Convolutional Block Attention Module(CBAM) Transformer (DSC-Transformer) for lymph node ultrasound image classification. The model integrates semantic feature extraction and multi-s...

(This article belongs to the Section Biosignal Processing)
  • Article
  • Open Access
2 Citations
1,121 Views
13 Pages

23 September 2025

The filtration behaviors of dynamic membrane (DM) under gravity-driven and pump-driven modes were investigated in a pilot-scale DM bioreactor (DMBR) for domestic wastewater treatment. After DM formation, both modes achieved effective solid–liqu...

(This article belongs to the Section Wastewater Treatment and Reuse)
  • Review
  • Open Access
75 Citations
19,824 Views
46 Pages

10 July 2019

Centrosomes and primary cilia are usually considered as distinct organelles, although both are assembled with the same evolutionary conserved, microtubule-based templates, the centrioles. Centrosomes serve as major microtubule- and actin cytoskeleton...

(This article belongs to the Special Issue Molecular Regulation of Mitosis and Its Role in Disease)
  • Article
  • Open Access
9 Citations
3,254 Views
27 Pages

19 February 2025

Relocatable modular buildings (RMBs) offer significant advantages, including flexibility, mobility, and scalability, making them ideal for temporary or rapidly changing scenarios. However, as the scale and quantity of RMB modules increase, their allo...

(This article belongs to the Special Issue Advanced Technologies in Construction and Infrastructure: Theory, Methods and Applications—2nd Edition)
  • Article
  • Open Access
816 Views
20 Pages

28 February 2026

Accurate carbon price predictions are vital for supporting the effective functioning of the carbon market. Most existing studies rely on point-valued modeling, thus failing to fully explore interval-valued data and mixed-frequency information. To add...

(This article belongs to the Special Issue Data-Driven Modeling and Predictive Analysis in Business, Social, Economic, Education, and Engineering Applications (2nd Edition))
  • Article
  • Open Access
48 Citations
13,988 Views
15 Pages

Field Performance of South-Facing and East-West Facing Bifacial Modules in the Arctic

  • Christopher Pike,
  • Erin Whitney,
  • Michelle Wilber and
  • Joshua S. Stein

23 February 2021

This paper presents the first systematic comparison between south-facing monofacial and bifacial photovoltaic (PV) modules, as well as between south-facing bifacial and vertical east-west facing bifacial PV modules in Alaska. The state’s solar indust...

(This article belongs to the Special Issue Increasing the Lifetime of Photovoltaics Systems: Advanced Materials, Monitoring, O&M and Energy Modeling)
  • Article
  • Open Access
7 Citations
3,776 Views
14 Pages

Development of a Soft Robotics Module for Active Control of Sitting Comfort

  • Tjark Roozendaal,
  • Martin Verwaal,
  • Alice Buso,
  • Rob B. N. Scharff and ,
  • Yu Song and
  • Peter Vink
  • + 1 author+ 0 author

20 March 2022

Sitting comfort is an important factor for passengers in selecting cars, airlines, etc. This paper proposes a soft robotic module that can be integrated into the seat cushion to provide better comfort experiences to passengers. Building on rapid manu...

(This article belongs to the Special Issue Integrated Fabrication Approaches for Soft Robotics)
  • Article
  • Open Access
1 Citations
2,983 Views
18 Pages

2 November 2022

Variable stiffness actuators (VSA) have attracted much attention because of their potential for human-like interaction behaviors. This paper devotes to improving the VSA’s versatility. VSA with different characteristics can be obtained by shape...

(This article belongs to the Special Issue Advanced Mathematical Modeling and Numerical Solutions in Applied Mechanics and Engineering)
  • Review
  • Open Access
93 Citations
13,983 Views
28 Pages

17 August 2022

The current geometric increase in the global deployment of solar photovoltaic (PV) modules, both at utility-scale and residential roof-top systems, is majorly attributed to its affordability, scalability, long-term warranty and, most importantly, the...

(This article belongs to the Topic Solar Thermal Energy and Photovoltaic Systems)
  • Article
  • Open Access
764 Views
19 Pages

Knowledge-Driven Adaptive Direct Sampling for Reconstructing Geochemical Fields Under Sampling Bias

  • Yameng Liu,
  • Jiali Zi,
  • Yanqi Dong,
  • Nuo Xu and ,
  • Qing Zhang and
  • Feixiang Chen
  • + 1 author+ 0 author

Deriving meaningful mineralization information from raw geospatial datasets is fundamental to the sustainable evaluation and management of mineral resources. As a cornerstone of mineral resource evaluation, identifying geochemical anomalies often fac...

(This article belongs to the Special Issue Spatial Data Science and Knowledge Discovery)
  • Article
  • Open Access
333 Views
22 Pages

19 September 2026

Despite advances in digital engineering tools, early-stage sheet metal forming tooling design remains strongly dependent on the tacit knowledge of experienced engineers, making systematic knowledge reuse difficult. This study addresses the need for a...

(This article belongs to the Special Issue Innovations and Insights in Sheet Metal Forming)
  • Article
  • Open Access
11 Citations
12,679 Views
11 Pages

A Novel Docking System for Modular Self-Reconfigurable Robots

  • Tan Zhang,
  • Wenjun Zhang and
  • Madan M. Gupta

10 October 2017

Existing self-reconfigurable robots achieve connections and disconnections by a separate drive of the docking system. In this paper, we present a new docking system with which the connections and disconnections are driven by locomotion actuators, wit...

  • Article
  • Open Access
1,223 Views
17 Pages

Research on Signal Processing Methods for White-Light-Driven Resonant Fiber Optic Gyroscope

  • Wenjing Yang,
  • Hongtao Zhu,
  • Wei Gao,
  • Lingyu Li and
  • Guochen Wang

29 January 2026

In white-light-driven resonant fiber optic gyroscopes (W-RFOG), modulation and demodulation techniques are essential for signal detection. Currently, in phase modulation and synchronous demodulation, the selection of relevant modulation waveforms and...

(This article belongs to the Special Issue Optical Fiber Sensors: Design and Application)
  • Article
  • Open Access
10 Citations
3,804 Views
17 Pages

Kinematic Modelling and Experimental Validation of a Foldable Pneumatic Soft Manipulator

  • Zhuoqun Liu,
  • Xiang Zhang,
  • Hongwei Liu,
  • Yong Chen and ,
  • Yiyong Huang and
  • Xiaoqian Chen
  • + 1 author+ 0 author

20 February 2020

A foldable pneumatic soft manipulator, which has the foldability to switch between a contraction state and an expanded state, is proposed in this investigation. The soft manipulator is a structure composed of pneumatic actuators and inflatable straig...

(This article belongs to the Special Issue Modeling, Design, and Optimization of Flexible Mechanical Systems)
  • Article
  • Open Access
5 Citations
3,649 Views
18 Pages

Hypoxia-Driven TGFβ Modulation of Side Population Cells in Breast Cancer: The Potential Role of ERα

  • Paraskevi Mallini,
  • Miaojuan Chen,
  • Kamilla Mahkamova,
  • Thomas W. J. Lennard and ,
  • Yue Pan,
  • Dan Wei,
  • Katherine Stemke-Hale,
  • John A. Kirby,
  • Gendie E. Lash and
  • Annette Meeson
  • + 5 authors+ 0 author

9 February 2023

Epithelial-to-mesenchymal transition (EMT) is known to be important in regulating the behaviour of cancer cells enabling them to acquire stem cell characteristics or by enhancing the stem cell characteristics of cancer stem cells, resulting in these...

(This article belongs to the Topic Molecular and Cellular Mechanisms of Cancers: Breast Cancer)
  • Article
  • Open Access
15 Citations
6,834 Views
12 Pages

Brain–computer interfaces (BCIs) based on code-modulated visual evoked potentials (c-VEPs) typically utilize a synchronous approach to identify targets (i.e., after preset time periods the system produces command outputs). Hence, users have onl...

  • Article
  • Open Access
2 Citations
1,890 Views
21 Pages

HER2-Driven Breast Cancer: Role of the Chaperonin HSP90 in Modulating Response to Trastuzumab-Based Therapeutic Combinations

  • Italia Falcone,
  • Elena Giontella,
  • Stefano Giuliani,
  • Giulia Borghesani and ,
  • Alessandro Valenti,
  • Valentina Zambonin,
  • Sara Monteverdi,
  • Luisa Carbognin,
  • Emilio Bria and
  • Michele Milella
  • + 20 authors+ 15 authors

Mechanistic relationships between heat shock protein 90 (HSP90) and human epidermal growth factor receptor 2 (HER2) are complex and clinical correlations in breast cancer remain inconsistent. We investigated the role of HSP90 expression in the respon...

(This article belongs to the Special Issue Predictive, Prognostic Biomarkers and Therapeutic Targets of Breast Cancer)
  • Article
  • Open Access
2 Citations
1,897 Views
23 Pages

Integrative Mechanistic Studies Identify Reticulon-3 as a Critical Modulator of Infectious Exosome-Driven Dengue Pathogenesis

  • Razieh Bitazar,
  • Clinton Njinju Asaba,
  • Saina Shegefti,
  • Tatiana Noumi and ,
  • Julien Van Grevenynghe,
  • Salim T. Islam,
  • Patrick Labonté and
  • Terence Ndonyi Bukong
  • + 3 authors+ 0 author

13 September 2025

The dengue virus (DENV) exploits host cell exosome pathways to disseminate and evade immunity. However, the host factors enabling this process remain poorly defined. Here, we demonstrate that DENV infection robustly induces expression of the short is...

(This article belongs to the Section Human Virology and Viral Diseases)
  • Communication
  • Open Access
1 Citations
1,921 Views
8 Pages

Four-Fold, Cross-Phase Modulation Driven UV Pulse Compression in a Thin Bulk Medium

  • Peter Susnjar,
  • Alexander Demidovich,
  • Gabor Kurdi,
  • Paolo Cinquegrana and ,
  • Ivaylo Nikolov,
  • Paolo Sigalotti and
  • Miltcho B. Danailov
  • + 2 authors+ 0 author

Generation of high energy few-fs pulses in the ultraviolet (UV) still represents challenges due to compression and phase control difficulties in this spectral range. Presented here is a pulse compression approach utilizing cross-phase modulation with...

(This article belongs to the Section Lasers, Light Sources and Sensors)
  • Article
  • Open Access
2 Citations
930 Views
18 Pages

PET-Driven Fluorescence Modulation in Halochromic Styryl Hemicyanine Dyes Targeting DNA Minor Groove

  • Teodora Aleksandrova,
  • Aleksandar Pashev,
  • Sonia Ilieva,
  • Raimundo Gargallo and ,
  • Diana Cheshmedzhieva and
  • Aleksey Vasilev
  • + 1 author+ 0 author

30 November 2025

A new series of styryl hemicyanine dyes featuring substituted N-phenylpiperazine end groups was synthesized using an environmentally friendly procedure. The photophysical properties of the dyes were systematically investigated in organic solvents of...

(This article belongs to the Special Issue Heterocyclic Compounds: Synthesis, Application and Theoretical Study)
  • Article
  • Open Access
21 Citations
5,080 Views
17 Pages

The recent success of machine learning has accelerated the development of data-driven lithium-ion battery state estimation and prediction. The lack of accessible battery operation data is one of the primary concerns with the data-driven approach. How...

(This article belongs to the Special Issue Recent Advances in Synthetic Data Generation)

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