Molecular Mechanisms and Therapeutic Targets in Cardiovascular Health and Cardiotoxicity
A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Pathology, Diagnostics, and Therapeutics".
Deadline for manuscript submissions: 30 November 2025 | Viewed by 26
Special Issue Editor
Interests: proteomic; bioinformatic; body fluids; integrative analysis; pipelines
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Cardiovascular diseases remain the leading cause of morbidity and mortality worldwide, and the molecular underpinnings of these conditions are under active investigation. This Special Issue aims to provide a platform for high-quality original research and reviews focusing on the molecular mechanisms involved in cardiovascular physiology and pathophysiology, including ischemia, heart failure, arrhythmogenesis, myocardial remodeling, and endothelial dysfunction.
We particularly welcome studies elucidating the role of genes, non-coding RNAs, proteins, metabolites, oxidative stress, inflammation, and mitochondrial dynamics in cardiovascular health and disease. Another key area of focus is the molecular basis of cardiotoxicity induced by chemotherapeutic agents, environmental stressors, or novel therapeutic interventions.
This Special Issue invites contributions using molecular biology, biochemistry, pharmacology, and omics technologies to uncover new biomarkers, molecular pathways, and potential therapeutic targets in cardiology and cardio-oncology. Studies involving both in vitro and in vivo models, as well as translational approaches with molecular depth, are encouraged.
By assembling a collection of molecular-level investigations, this Special Issue will help advance our understanding of cardiovascular disease mechanisms and support the development of targeted interventions to improve clinical outcomes.
Dr. Rui Vitorino
Guest Editor
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. International Journal of Molecular Sciences is an international peer-reviewed open access semimonthly journal published by MDPI.
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Keywords
- cardiovascular
- ischemia, heart failure
- arrhythmogenesis
- myocardial remodeling
- endothelial dysfunction
- cardiology
- cardio-oncology
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