16 May 2021
Objective: To compare the reliability of digital occlusal contacts quantification and the validity of digital occlusal contacts quantification with traditional methods used for occlusal contact determination. Subjects and Methods: Thirty participants...
Liver disease has been targeted as the fifth most common cause of death worldwide and tends to steadily rise. In the last three decades, several publications focused on the quantification of liver fibrosis by means of the estimation of the collagen p...
In this case study, we explored quantitative 1H NMR (qNMR), HPLC-DAD, and the Folin-Ciocalteu assay (TPC) as methods of quantifying the total phenolic content of a green macroalga, Ulva intestinalis, after optimized accelerated solvent extraction. Te...
While biodegradable plastics alleviate plastic pollution, their degradation-derived biodegradable microplastics (BMPs) pose new ecological risks, necessitating efficient quantification methods. This study explores a label-free approach by leveraging...
Background: The anatomy laboratory can provide the ideal setting for the preclinical phase of neurosurgical research. Our purpose is to comprehensively and critically review the preclinical anatomical quantification methods used in cranial neurosurge...
Biphasic oil/water nanoemulsions have been proposed as delivery systems for the intranasal administration of curcumin (CUR) and quercetin (QU), due to their high drug entrapment efficiency, the possibility of simultaneous drug administration and prot...
The proviral load of human T-cell lymphotropic virus type 1 (HTLV-1) is an important biomarker associated with the monitoring and risk stratification of adult T-cell leukemia/lymphoma (ATL) and HTLV-1-associated myelopathy/tropical spastic paraparesi...
Objective: The present pilot study aimed to propose an innovative scale-independent measure based on electroencephalographic (EEG) signals for the identification and quantification of the magnitude of chronic pain. Methods: EEG data were collected fr...
Lung cancer is a leading cause of cancer-related deaths globally. Early detection is crucial for improving patient survival rates. Deep learning (DL) has shown promise in the medical field, but its accuracy must be evaluated, particularly in the cont...
Muricidae are marine molluscs known for the production of Tyrian purple and bioactive precursor compounds. A validation study for the extraction and analysis of secondary metabolites found in the hypobranchial gland of the muricid Dicathais orbita is...
A phase present in small quantities within materials may not simply serve as a secondary component; it can play a crucial role in determining the integrity, properties, and performance of the material. These minor but important phases usually draw at...
Background/Objectives: Tenosynovitis is a common feature of psoriatic arthritis (PsA) and is typically assessed using semi-quantitative magnetic resonance imaging (MRI) scoring. However, visual scoring s variability. This study evaluates a fully auto...
This study aimed to investigate which of the two frequently adopted perfusion models better describes the contrast enhanced ultrasound (CEUS) perfusion signal in order to produce meaningful imaging markers with the goal of developing a machine-learni...
The quantification of the irregular morphology and distribution pattern of mineral grains is an essential but challenging task in ore-related mineralogical research, allowing for tracing the footprints of pattern-forming geological processes that are...
In this study, a concentration overvoltage model that focuses on describing variable-temperature operating condition properties for PEMFCs is established. Sensitivity analysis and a quantification study of oxygen transport resistance are carried out...
Background: Traditional neonatal assessments rely on anthropometric measures such as weight, body size, and head circumference. However, recent studies suggest that objective movement quantification may serve as a complementary clinical indicator of...
The use of plastics in agriculture and in fisheries has been vital to increase food production and meet the demands of an increasingly growing global population. However, there are several drawbacks to the use of plastics in these industries. Most pl...
Sialyllactose (SL), an acidic oligosaccharide, has immune-protective effects against pathogens and helps with the development of the immune system and intestinal microorganisms. To elucidate the pharmacokinetic characterization after oral administrat...
Arterial spin labeling (ASL) MRI allows non-invasive quantification of renal blood flow (RBF) and shows great potential for renal assessment. To our knowledge, renal ASL-MRI has not previously been performed in dogs. The aim of this pilot study was t...
An ultra-performance liquid chromatography with photodiode array (UPLC-PDA) UV detection method was developed here for the first time for simple, rapid, selective and sensitive quantification of the commonly prescribed selective cyclooxygenase-2 (COX...
Metal additive manufacturing is now taking the lead over traditional manufacturing techniques in applications such as aerospace and biomedicine, which are characterized by low production volumes and high levels of customization. While fulfilling thes...
Coastal urban areas in Indonesia commonly encounter complex environmental problems, including bad air pollution and high risk of flooding due to sea level rise and land subsidence. The existence of urban mangrove forests potentially contributes to mi...
Background/Objectives: AC02 is a novel 39-amino-acid adrenocorticotropic hormone (ACTH) analogue designed for the treatment of infantile spasms. To support its clinical study, in which porcine ACTH1–39 served as the positive-control drug, relia...
In response to the urgent need for developing super-low-energy buildings (SLEBs) under extreme climatic conditions, a critical research gap lies in scientifically quantifying the passive climate adaptation mechanisms of vernacular architecture and tr...
Introduction: Oral squamous cell carcinoma (OSCC) is one of the most common tumours worldwide. This study investigated the suitability of visible and near-infrared hyperspectral imaging compared to visual assessment and conventional digital image ana...
Analytical methods for the quantification of the new 8-aminoquinoline antimalarial tafenoquine (TQ) in human blood, plasma and urine, and the 5,6-orthoquinone tafenoquine metabolite (5,6-OQTQ) in human plasma and urine have been validated. The proced...
Unilateral spatial neglect is a common sensorimotor disorder following the occurrence of a stroke, for which prismatic adaptation is a promising rehabilitation method. However, the use of prisms for rehabilitation often requires the use of specific e...
Blood flow rate in dialysis (vascular) access is the key parameter to examine patency and to evaluate the outcomes of various endovascular interve7ntions. While angiography is extensively used for dialysis access–salvage procedures, to date, there is...
The genotoxicity, mutagenesis, and carcinogenic effects of polycyclic aromatic hydrocarbon (PAH) derivatives may exceed the parent PAHs. However, their influence on the soil environment has not been explored to a large extent. Oxygenated polycyclic a...
Background: For manual wheelchair users, overuse of the upper limbs can cause upper limb musculoskeletal disorders, which can lead to a loss of autonomy. The main objective of this study was to quantify the risk level of musculoskeletal disorders of...
Measuring biological drugs’ trough concentrations and the concentrations of anti-drug antibodies is a valuable practice for treatment optimization. ELISA techniques are the gold standard for biological drug concentration quantification, but new...
The aim of this study is to determine the total iodine content in Korean abalone (Haliotis discus hannai) and to investigate the bioavailability of iodine using an in vitro method. This research paper focuses on total iodine quantification in abalone...
Conventional approaches for badminton biomechanics assessment, such as optical motion capture, force plates, and wearable inertial sensors, are limited by occlusion, restricted coverage, or intrusiveness during high-intensity on-court movement. To ad...
Propylthiouracil (PTU) is commonly prescribed for the management of hyperthyroidism and thyrotoxicosis. Although the exact mechanism of action is not fully understood, PTU is associated with hepatoxicity in pediatric population. Glucuronidation media...
The quantification of synergistic effects of multi-combination compounds is critical in developing “cocktails” that are efficacious. In this research, a method for in silico modeling and the quantification of synergistic effects of multi-...
The massive integration of renewable electricity places significant regulatory pressure on urban power grids. This has also promoted the development of virtual power plant technology. The air conditioning systems of public buildings, as one of the ma...
In the new energy systems’ modeling paradigm with high temporal and spatial resolutions, the complexity of renewable resources and demand dynamics is a major obstacle for the scenario analysis of future energy systems and the design of sustaina...
In submerged arc welding, evaluating elemental transfer behaviors is critical for selecting and designing welding materials. Accurate assessment of O, Si, and Mn transfer behavior is essential for ensuring process quality, particularly when silicon-m...
A reliable and practical renal-lipid quantification and imaging method is needed. Here, the feasibility of an accelerated MRSI method to map renal fat fractions (FF) at 3T and its repeatability were investigated. A 2D density-weighted concentric-ring...
Volatile organic compounds (VOCs) represent one of the most important categories of pollutants, influencing the air quality and human health and well-being in indoor environments. In the present study, 12 selected VOCs were sampled using Tenax TA tub...
The stability of a new coumarin derivative, agent K-142, bearing α-pinene residue and possessing antiviral activity against respiratory syncytial virus (RSV) was studied in whole mice blood in vitro, and a method for its quantification in this...
Under China’s rural revitalization strategy, peri-urban villages function as pivotal nodes in urban–rural integration. Existing policy research predominantly emphasizes macro-level land and industrial policies, neglecting their spatial de...
Bile acids (BA) play a pivotal role in cholesterol metabolism. Their blood concentration has also been proposed as new prognostic and diagnostic indicator of hepatobiliary, intestinal, and cardiovascular disease. Liquid chromatography tandem mass spe...
This proof-of-concept study aimed to evaluate a novel method of flow cytometry-based quantification of neutrophil extracellular traps (NETs) in septic shock patients and to identify possible interactions between the number of free-circulating NETs an...
This study was conducted to support the development of a novel generic veterinary formulation by performing a comparative pharmacokinetic analysis against an approved reference product (Bravecto® Plus). Sensitive and selective liquid chromatograp...
This study aimed to establish a simple and sensitive analytical method to simultaneously quantify donepezil (DPZ) and tadalafil (TAD) in rat plasma using lansoprazole (LPZ) as an internal standard (IS) by using liquid chromatography tandem mass spect...
Obesity is a risk factor of chronic kidney disease (CKD), leading to alterations in the renal vascular structure. This study tested if renal vascular density and tortuosity was quantifiable in vivo in obese rats using microbubble-based super-resoluti...
Information regarding per- and polyfluorinated substances concentrations in biological samples from the Thai population was still lacking. A sensitive bioanalytical method was developed and validated for the quantification of perfluorooctane sulfonic...
Transthoracic echocardiography (TTE) grading of aortic stenosis (AS) is challenging when parameters are discrepant, and four-dimensional cardiac computed tomography (4D-CCT) is increasingly utilized for transcatheter intervention workup. We compared...
Background: An important determinant of mortality in AS is the presence and quantity of myocardial scar. Scar quantification using late gadolinium enhancement (LGE) on cardiovascular magnetic resonance (CMR) imaging may be a useful risk-stratificatio...
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