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167 Results Found

  • Communication
  • Open Access
27 Citations
7,858 Views
13 Pages

Creation of a Plant Metabolite Spectral Library for Untargeted and Targeted Metabolomics

  • Yangyang Li,
  • Wei Zhu,
  • Qingyuan Xiang,
  • Jeongim Kim and ,
  • Craig Dufresne,
  • Yufeng Liu,
  • Tianlai Li and
  • Sixue Chen
  • + 3 authors+ 0 author

23 January 2023

Large-scale high throughput metabolomic technologies are indispensable components of systems biology in terms of discovering and defining the metabolite parts of the system. However, the lack of a plant metabolite spectral library limits the metaboli...

(This article belongs to the Special Issue Advances in Molecular Plant Sciences)
  • Article
  • Open Access
18 Citations
5,442 Views
17 Pages

7 January 2020

In recent years, due to the advantages of high construction efficiency and less environmental pollution, prefabricated housing has been of increasing interest and vigorously promoted. However at present, most prefabricated houses simply pursue an inc...

(This article belongs to the Special Issue Design and Management of Sustainable Products, Industrial and Manufacturing Systems)
  • Article
  • Open Access
34 Citations
9,212 Views
11 Pages

Alteration of the Donor/Acceptor Spectrum of the (S)-Amine Transaminase from Vibrio fluvialis

  • Maika Genz,
  • Clare Vickers,
  • Tom Van den Bergh,
  • Henk-Jan Joosten and ,
  • Mark Dörr,
  • Matthias Höhne and
  • Uwe T. Bornscheuer
  • + 2 authors+ 0 author

11 November 2015

To alter the amine donor/acceptor spectrum of an (S)-selective amine transaminase (ATA), a library based on the Vibrio fluvialis ATA targeting four residues close to the active site (L56, W57, R415 and L417) was created. A 3DM-derived alignment compr...

(This article belongs to the Special Issue Molecular Biocatalysis)
  • Article
  • Open Access
1,811 Views
13 Pages

25 November 2024

In this paper, the authors present the possibilities of transnational networking and developing innovative cultural routes through participatory research and creative presentations of European cultural heritage in special collections of Adriatic libr...

  • Article
  • Open Access
1,957 Views
17 Pages

Librarian: An Open-Access Web Application for High-Resolution Mass Spectral Library Assembly

  • Jacob Ahlberg Weidenfors,
  • Bénilde Bonnefille and
  • Stefano Papazian

Background: Confident chemical annotation in nontarget small-molecule mass spectrometry critically depends on the availability of high-quality tandem mass spectral (MS2) reference libraries. While community efforts have driven significant expansion o...

(This article belongs to the Special Issue Open-Source Software in Metabolomics, 2nd Edition)
  • Review
  • Open Access
735 Views
11 Pages

23 July 2026

Unlike conventional screening methods, which are limited by library size, DNA-encoded chemical library (DEL) technology enables the simultaneous interrogation of billions of compounds, each uniquely barcoded with DNA tags. These libraries can be scre...

(This article belongs to the Collection Will (Radio)Theranostics Hold Up in the 21st Century—and Why?)
  • Article
  • Open Access
2 Citations
2,550 Views
17 Pages

Academic Libraries as Partners in Data Literacy Education—An Explorative Case Study

  • Simone Fühles-Ubach,
  • Elisabeth Kaliva and
  • Martina Echtenbruck

The concept of the ‘teaching library’, which originated in the Anglo-American world, describes all activities of libraries in the field of promoting information, media, and data literacy, as well as other skills in dealing with analog and...

(This article belongs to the Special Issue Academic Libraries in Supporting Research)
  • Article
  • Open Access
145 Citations
25,232 Views
26 Pages

Improving Sexual Health Education Programs for Adolescent Students through Game-Based Learning and Gamification

  • Hussein Haruna,
  • Xiao Hu,
  • Samuel Kai Wah Chu,
  • Robin R. Mellecker and ,
  • Goodluck Gabriel and
  • Patrick Siril Ndekao
  • + 1 author+ 0 author

An effective innovative pedagogy for sexual health education is required to meet the demands of technology savvy digital natives. This study investigates the extent to which game-based learning (GBL) and gamification could improve the sexual health e...

  • Article
  • Open Access
192 Views
21 Pages

27 October 2026

Artificial intelligence (AI) is reshaping library services worldwide, yet little is known about its integration into South African academic libraries. This study analyzed AI-assisted services and emerging practices in South African university librari...

  • Article
  • Open Access
2 Citations
8,155 Views
19 Pages

27 May 2014

A considerable amount of information, particularly in image form, is shared on the web through social networking sites. If any of this content is worthy of preservation, who decides what is to be preserved and based on what criteria. This paper explo...

(This article belongs to the Special Issue Archiving Community Memories)
  • Perspective
  • Open Access
2 Citations
3,762 Views
15 Pages

The article aims to reflect on the Lodovico media library, a digital repository preserving the digitised cultural heritage of the Emilia-Romagna region. The first part covers the project’s history and the challenges encountered during its setup...

  • Article
  • Open Access
5 Citations
2,957 Views
13 Pages

Strawberry Volatile Organic Compounds for Targeted Metabolomics: The AMDIS Strawberry User Library from Korean Germplasm

  • Eunsu Do,
  • Eungu Jee,
  • Chan Saem Gil,
  • Seolah Kim and ,
  • Sun Yi Lee and
  • Kang-Mo Ku
  • + 1 author+ 0 author

Strawberry aroma, crucial for determining quality, involves complex volatile compounds which are challenging to identify. This study explores strawberry aroma analysis using Gas Chromatography-Mass Spectrometry (GC-MS) and the Automated Mass Spectral...

(This article belongs to the Section Postharvest Biology, Quality, Safety, and Technology)
  • Article
  • Open Access
22 Citations
9,717 Views
11 Pages

1 November 2021

The work of libraries during the COVID-19 pandemic, as facilitators of reliable information on health issues, has shown that these entities can play an active role as verification agents in the fight against disinformation (false information that is...

(This article belongs to the Special Issue Fighting Fake News: A Generational Approach)
  • Article
  • Open Access
40 Citations
9,497 Views
24 Pages

16 November 2015

One of the main applications of field spectroscopy is the generation of spectral libraries of Earth’s surfaces or materials to support mapping activities using imaging spectroscopy. To enhance the reliability of these libraries, spectral signature ac...

  • Article
  • Open Access
11 Citations
8,512 Views
15 Pages

Interoperability and social implication are two current challenges in the digital library (DL) context. To resolve the problem of interoperability, our work aims to find a relationship between the main metadata schemas. In particular, we want to form...

(This article belongs to the Special Issue Human–Computer Interaction and the Social Web)
  • Article
  • Open Access
1 Citations
1,839 Views
28 Pages

22 February 2025

Rising antifungal resistance prompted the World Health Organization and the Food and Agriculture Organization to bring attention to the consequences of this threat to human, animal, and environmental health, and food security. In addition, there is a...

(This article belongs to the Section Molecular Immunology)
  • Article
  • Open Access
4 Citations
4,516 Views
43 Pages

DynPy—Python Library for Mechanical and Electrical Engineering: An Assessment with Coupled Electro-Mechanical Direct Current Motor Model

  • Damian Sierociński,
  • Bogumił Chiliński,
  • Franciszek Gawiński,
  • Amadeusz Radomski and
  • Piotr Przybyłowicz

13 January 2025

DynPy is an open-source library implemented in Python (version 3.10.12) programming language which aims to provide a versatile set of functionalities for mechanical and electrical engineers. It enables the user to model, solve, simulate, and report a...

(This article belongs to the Special Issue Linear and Nonlinear Electric Circuits: Theoretical Analysis and Applications—2nd Edition)
  • Project Report
  • Open Access
19 Citations
8,725 Views
18 Pages

As research topics become increasingly complex, large scale interdisciplinary research projects are commonly established to foster cross-disciplinary cooperation and to utilize potential synergies. In the case of the Collaborative Research Center (CR...

(This article belongs to the Special Issue Research Data Management)
  • Article
  • Open Access
28 Citations
4,242 Views
19 Pages

Artificial Intelligence Aided Design of Microtextured Surfaces: Application to Controlling Wettability

  • Andrés Díaz Lantada,
  • Francisco Franco-Martínez,
  • Stefan Hengsbach,
  • Florian Rupp and ,
  • Richard Thelen and
  • Klaus Bade
  • + 1 author+ 0 author

18 November 2020

Artificial intelligence (AI) has emerged as a powerful set of tools for engineering innovative materials. However, the AI-aided design of materials textures has not yet been researched in depth. In order to explore the potentials of AI for discoverin...

(This article belongs to the Special Issue Multifunctional 2D and 3D Nano and Microtextured Interfaces: From Medical to Environmental and Sensing Applications)
  • Article
  • Open Access
17 Citations
5,168 Views
14 Pages

A Low-Cost Interactive Writing Board for Primary Education using Distinct Augmented Reality Markers

  • Dawar Khan,
  • Inam ur Rehman,
  • Sehat Ullah,
  • Waheed Ahmad and ,
  • Zhanglin Cheng,
  • Gul Jabeen and
  • Hirokazu Kato
  • + 2 authors+ 0 author

16 October 2019

Educational institutions demand cost-effective and simple-to-use augmented reality systems. ARToolKit, an open-source computer tracking library for the creation of augmented reality applications that overlay virtual imagery on the real world, is such...

  • Article
  • Open Access
7 Citations
3,827 Views
16 Pages

7 April 2022

In this paper, we compare three different models of multilayer neural networks in terms of their success in the classification phase. These models were designed for EmguCV, ML.NET and Tensorflow.Net libraries, which are currently among the most widel...

(This article belongs to the Topic Applied Computer Vision and Pattern Recognition)
  • Article
  • Open Access
6 Citations
6,953 Views
13 Pages

11 August 2019

QuickStep is a cloning method that allows seamless point integration of a DNA sequence at any position within a target plasmid using only Q5 High-Fidelity DNA Polymerase and DpnI endonuclease. This efficient and cost-effective method consists of two...

(This article belongs to the Special Issue A Commemorative Issue to Celebrate the Nobel Success of Prof. Frances H. Arnold: Directed Evolution)
  • Article
  • Open Access
4 Citations
2,670 Views
17 Pages

Selection of Flax Genotypes for Pan-Genomic Studies by Sequencing Tagmentation-Based Transcriptome Libraries

  • Elena N. Pushkova,
  • Elena V. Borkhert,
  • Roman O. Novakovskiy,
  • Ekaterina M. Dvorianinova and ,
  • Tatiana A. Rozhmina,
  • Alexander A. Zhuchenko,
  • Daiana A. Zhernova,
  • Anastasia A. Turba,
  • Arthur G. Yablokov and
  • Alexey A. Dmitriev
  • + 9 authors+ 4 authors

30 October 2023

Flax (Linum usitatissimum L.) products are used in the food, pharmaceutical, textile, polymer, medical, and other industries. The creation of a pan-genome will be an important advance in flax research and breeding. The selection of flax genotypes tha...

(This article belongs to the Special Issue Flax: A Traditional Culture with Modern Advantages)
  • Review
  • Open Access
8 Citations
6,160 Views
17 Pages

New Frontiers of Electronic Theses and Dissertations

  • Joachim Schöpfel,
  • Michael Boock,
  • Behrooz Rasuli and
  • Brenda van Wyk

(1) Background: Since the 1990s, theses and dissertations—a key part of scientific communication—have evolved significantly with advances in information and communication technologies. (2) Methods: This study reviews 99 publications exami...

(This article belongs to the Section Arts & Humanities)
  • Article
  • Open Access
2 Citations
6,974 Views
15 Pages

Service management—the entirety of activities undertaken by an organization to design, plan, deliver, operate, and control information technology (IT) services offered to stakeholders—has long been applied successfully by the government a...

(This article belongs to the Special Issue Selected Papers from Open Repositories 2018)
  • Article
  • Open Access
4 Citations
1,865 Views
18 Pages

26 October 2024

Sodium–glucose co-transporter 1 (SGLT1) is primarily expressed on the membrane of enterocytes, a type of epithelial cell found in the intestines, where it mediates the unidirectional absorption of glucose and galactose. Beyond its well-establis...

(This article belongs to the Special Issue Glycomimetics: Design, Synthesis and Bioorganic Applications)
  • Article
  • Open Access
11 Citations
5,195 Views
11 Pages

Development and Large-Scale Production of High-Oleic Acid Oil by Fermentation of Microalgae

  • Leon Parker,
  • Kevin Ward,
  • Thomas Pilarski,
  • James Price and ,
  • Paul Derkach,
  • Mona Correa,
  • Roberta Miller,
  • Veronica Benites,
  • Dino Athanasiadis and
  • Scott Franklin
  • + 13 authors+ 8 authors

Our classical strain improvement began with an isolate showing 28% palmitic and 60% oleic acids. UV and chemical mutagenesis enhanced our strain’s productivity, carbon yield, and oleic acid content. The iterative methodology we used involved th...

(This article belongs to the Special Issue Precision Fermentation: Applications in the Food and Beverage Industry)
  • Article
  • Open Access
7 Citations
5,821 Views
27 Pages

A Non-Invasive and Sustainable Characterization of Pigments in Wall Paintings: A Library of Apulian Colors

  • Giovanna Fioretti,
  • Marina Clausi,
  • Giacomo Eramo,
  • Elisabetta Longo and ,
  • Alessandro Monno,
  • Daniela Pinto and
  • Gioacchino Tempesta
  • + 2 authors+ 0 author

1 February 2023

This paper proposed a multianalytical, non-invasive, accessible and expensive (compared to traditional ones) approach for the characterization of pictorial surfaces. A set of 18 pigments and 37 mixtures widely used in the Middle Ages in the Apulia (I...

(This article belongs to the Special Issue Advances in Italian Research Applied to Cultural Heritage)
  • Article
  • Open Access
11 Citations
4,538 Views
15 Pages

10 February 2024

A continuing need to improve health, safety and wellbeing in construction has led to multiple research projects and technological innovations. One such innovation is the Safety Risk Library: a repository of data that functions in BIM environments to...

(This article belongs to the Special Issue Advancing Occupational Health and Safety in Construction: Innovations, Education, and Training for a Safer Future)
  • Article
  • Open Access
1 Citations
1,003 Views
23 Pages

This paper combines the application of AI technology in the field of architectural design to construct a “three-stage model” (imitation, exploration, and creation) centered on cultivating students’ creative thinking and innovative a...

(This article belongs to the Topic Architectural Education)
  • Article
  • Open Access
1 Citations
2,583 Views
12 Pages

Development of a Tool for Navigating the Evidence concerning Land Managers and Woodland Creation in the United Kingdom

  • Gillian Petrokofsky,
  • Michael Dunn,
  • David Edwards,
  • William J. Harvey and ,
  • Gabriel E. Hemery,
  • Harry Marshall,
  • Stephen McConnachie,
  • Leo Petrokofsky,
  • Kevin Watts and
  • Bianca Ambrose-Oji
  • + 5 authors+ 0 author

4 February 2024

Woodland creation has become an important objective for a variety of stakeholders to help tackle the climate and biodiversity crises. One of the key evidence needs is a better understanding of the multiple factors influencing the willingness and abil...

(This article belongs to the Section Forest Economics, Policy, and Social Science)
  • Article
  • Open Access
2,893 Views
18 Pages

n-Tuples on Scaffold Diversity Inspired by Drug Hybridisation to Enhance Drugability: Application to Cytarabine

  • Miguel García-Castro,
  • David Fuentes-Rios,
  • J. Manuel López-Romero,
  • Antonio Romero and ,
  • Federico Moya-Utrera,
  • Amelia Díaz-Morilla and
  • Francisco Sarabia
  • + 2 authors+ 0 author

13 December 2023

A mathematical concept, n-tuples are originally applied to medicinal chemistry, especially with the creation of scaffold diversity inspired by the hybridisation of different commercial drugs with cytarabine, a synthetic arabinonucleoside derived from...

(This article belongs to the Section Synthesis and Medicinal Chemistry of Marine Natural Products)
  • Article
  • Open Access
31 Citations
5,634 Views
12 Pages

What Are the Best Practices for Co-Creating Patient-Facing Educational Materials? A Scoping Review of the Literature

  • Isabella R. McDonald,
  • Elizabeth S. Blocker,
  • Elizabeth A. Weyman,
  • Neil Smith and
  • Andrew A. Dwyer

23 September 2023

Co-creating patient-facing educational materials (PEMs) can enhance person-centered care by responding to patient priorities and unmet needs. Little data exist on ‘best practices’ for co-creation. We followed the Arksey and O’Malley...

(This article belongs to the Section Healthcare Quality, Patient Safety, and Self-care Management)
  • Review
  • Open Access
72 Citations
8,209 Views
13 Pages

Directed evolution was first applied to diverse libraries of DNA and RNA molecules a quarter century ago in the hope of gaining technology that would allow the creation of receptors, ligands, and catalysts on demand. Despite isolated successes, the o...

(This article belongs to the Special Issue Engineering Aptamers for Biomedical Applications)
  • Article
  • Open Access
12 Citations
8,792 Views
10 Pages

An Efficient New Route to Dihydropyranobenzimidazole Inhibitors of HCV Replication

  • Matthew A. Parker,
  • Emily Satkiewicz,
  • Thomas Hermann and
  • B. Mikael Bergdahl

30 December 2010

A class of dihydropyranobenzimidazole inhibitors was recently discovered that acts against the hepatitis C virus (HCV) in a new way, binding to the IRES-IIa subdomain of the highly conserved 5' untranslated region of the viral RNA and thus preventing...

  • Article
  • Open Access
533 Views
16 Pages

Cultural organizations, like museums, libraries, and archives, are trusted spaces for discovery, innovation, interrogation, and encouraging agency and exploration. They go beyond the physicality of objects, focusing on dissemination of knowledge as t...

(This article belongs to the Special Issue Controversial Heritage, Museums and History Education Challenges and Experiences from Democratic Culture and Critical Intersectionality)
  • Article
  • Open Access
1 Citations
835 Views
22 Pages

Optimization Techniques for Wind Turbine Power Recovery Using Average Models and Genetic Algorithms

  • Saber Hadj Abdallah,
  • Fatma Ben Salem,
  • Jaouhar Mouine and
  • Souhir Tounsi

25 November 2025

This paper presents a systemic design methodology for wind energy power systems. The foundation of this research is the creation of two average models of wind energy power systems, which are based on average value theory for power converters like rec...

  • Article
  • Open Access
23 Citations
9,932 Views
14 Pages

Recent developments in generative artificial intelligence tools have prompted immediate reactions in the academic library community. While most studies focus on the potential impact on academic integrity, this work explored constructive applications...

(This article belongs to the Special Issue 10th Anniversary Special Issue "PUBMET2023 Conference on Scholarly Communication in the Context of Open Science")
  • Article
  • Open Access
1,139 Views
22 Pages

Enhancing CuFP Library with Self-Alignment Technique

  • Fahimeh Hajizadeh,
  • Tarek Ould-Bachir and
  • Jean Pierre David

High-Level Synthesis (HLS) tools have transformed FPGA development by streamlining digital design and enhancing efficiency. Meanwhile, advancements in semiconductor technology now support the integration of hundreds of floating-point units on a singl...

  • Article
  • Open Access
3,913 Views
27 Pages

29 August 2025

Malicious actors often exploit persistence mechanisms, such as unauthorized modifications to Windows startup directories or registry keys, to achieve privilege escalation and maintain access on compromised systems. While information technology (IT) t...

(This article belongs to the Special Issue Security of Computer System and Network)
  • Article
  • Open Access
4 Citations
3,213 Views
17 Pages

The Standardization Method and Application of the BIM Model for Interchanges

  • Yiyang Zhai,
  • Chi Zhang,
  • Bo Wang,
  • Xue Wang and ,
  • Kai Liu and
  • Zhongze Tang
  • + 1 author+ 0 author

1 September 2022

Research on the standardization of interchange BIM components is required to encourage the use of BIM technology in interchange and quicken the development and improvement of relevant standards and specifications. The depth level of the model, classi...

(This article belongs to the Section Transportation and Future Mobility)
  • Article
  • Open Access
45 Citations
5,507 Views
24 Pages

Revolutionizing the Garment Industry 5.0: Embracing Closed-Loop Design, E-Libraries, and Digital Twins

  • Semih Donmezer,
  • Pinar Demircioglu,
  • Ismail Bogrekci,
  • Gokcen Bas and
  • Muhammet Numan Durakbasa

10 November 2023

This study presents an innovative approach for modernizing the garment industry through the fusion of digital human modeling (DHM), virtual modeling for fit sizing, ergonomic body-size data, and e-library resources. The integration of these elements...

(This article belongs to the Special Issue Sustainable Production & Operations Management)
  • Article
  • Open Access
312 Views
14 Pages

1 October 2026

The main objective of this study is to explore how pre-service teachers retrospectively describe differences between their prior and current perspectives following participation in a Human Library. This research begins with a review of the literature...

(This article belongs to the Special Issue Civic Education in the Digital Age)
  • Article
  • Open Access
7 Citations
7,220 Views
33 Pages

13 May 2025

The past 15 years of extensive experience teaching VR system development has taught us that haptic feedback must be more sophisticatedly integrated into VR systems, alongside the already realistic high-fidelity visual and audio feedback. The third ge...

(This article belongs to the Special Issue Enhancing User Experience in Virtual Reality Environments: Innovative Interaction Design Strategies)
  • Article
  • Open Access
4 Citations
3,478 Views
15 Pages

Directed Evolution of a Glutathione Transferase for the Development of a Biosensor for Alachlor Determination

  • Fereniki Perperopoulou,
  • Maria Fragoulaki,
  • Anastassios C. Papageorgiou and
  • Nikolaos E. Labrou

12 March 2021

In the present work, DNA recombination of three homologous tau class glutathione transferases (GSTUs) allowed the creation of a library of tau class GmGSTUs. The library was activity screened for the identification of glutathione transferase (GST) va...

(This article belongs to the Section E: Life Sciences)
  • Article
  • Open Access
22 Citations
5,372 Views
16 Pages

Applied Molecular-Based Quality Control of Biobanked Samples for Multi-Omics Approach

  • Anna Michalska-Falkowska,
  • Jacek Niklinski,
  • Hartmut Juhl,
  • Anetta Sulewska and ,
  • Joanna Kisluk,
  • Radoslaw Charkiewicz,
  • Michal Ciborowski,
  • Rodryg Ramlau,
  • Robert Gryczka and
  • Joanna Reszec-Gielazyn
  • + 14 authors+ 9 authors

24 July 2023

Biobanks are vital for high-throughput translational research, but the rapid development of novel molecular techniques, especially in omics assays, poses challenges to traditional practices and recommendations. In our study, we used biospecimens from...

  • Article
  • Open Access
3 Citations
4,378 Views
25 Pages

7 February 2025

This research introduces an artificial intelligence-based strategy for improving symbol recognition within the field of library science, concentrating on the creation and application of sophisticated technological solutions. Consistent with the objec...

  • Article
  • Open Access
78 Citations
24,616 Views
22 Pages

Inundation Mapping Initiatives of the Iowa Flood Center: Statewide Coverage and Detailed Urban Flooding Analysis

  • Daniel Gilles,
  • Nathan Young,
  • Harvest Schroeder,
  • Jesse Piotrowski and
  • Yi-Jia Chang

16 January 2012

The State of Iowa, located in the Midwestern United States, has experienced an increased frequency of large floods in recent decades. After extreme flooding in the summer of 2008, the Iowa Flood Center (IFC) was established for advanced research and...

(This article belongs to the Special Issue Flood Risk Management)
  • Article
  • Open Access
9 Citations
8,963 Views
22 Pages

Development and Validation of a Latent Thermal Energy Storage Model Using Modelica

  • Dre Helmns,
  • David H. Blum,
  • Spencer M. Dutton and
  • Van P. Carey

2 January 2021

An abundance of research has been performed to understand the physics of latent thermal energy storage with phase change material. Some analytical and numerical findings have been validated by experiments, but there are few free and open-source model...

(This article belongs to the Special Issue Thermal Energy Storage in Building Integrated Thermal Systems)

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